- Glycosylation of surface Ig creates a functional bridge between human follicular lymphoma and microenvironmental lectinsVania Coelho
Molecular Immunology Group, Cancer Sciences Division, University of Southampton, School of Medicine, Southampton SO16 6YD, United Kingdom
Proc Natl Acad Sci U S A 107:18587-92. 2010..This unique lymphoma-specific interaction of sIg with lectins of innate immunity reveals a potential route for microenvironmental support of tumor cells, mediated via the key B-cell receptor...
- Surface IgM of CLL cells displays unusual glycans indicative of engagement of antigen in vivoSergey Krysov
Molecular Immunology Group, Cancer Sciences Division, University of Southampton School of Medicine, Southampton, United Kingdom
Blood 115:4198-205. 2010..Strikingly, this is reminiscent of follicular lymphoma, where mannosylated Ig is expressed constitutively via N-glycosylation sites in the variable region, suggesting a functional asset for this glycoform...