Geoffrey Coast


Affiliation: University of London
Country: UK


  1. Coast G. Neuroendocrine control of ionic homeostasis in blood-sucking insects. J Exp Biol. 2009;212:378-86 pubmed publisher
    ..At such times, the hindgut has a negligible impact on the volume and composition of the final urine, and neurohormones acting on the Malpighian tubules have a dominant role in the control of ionic homeostasis. ..
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    Coast G, Webster S, Schegg K, Tobe S, Schooley D. The Drosophila melanogaster homologue of an insect calcitonin-like diuretic peptide stimulates V-ATPase activity in fruit fly Malpighian tubules. J Exp Biol. 2001;204:1795-804 pubmed
    ..Since the K+ concentration of the secreted urine was unchanged, it is likely that Drome-DH31 has an equal effect on K+ and Na+ entry across the basolateral membrane. ..
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    Coast G, Garside C, Webster S, Schegg K, Schooley D. Mosquito natriuretic peptide identified as a calcitonin-like diuretic hormone in Anopheles gambiae (Giles). J Exp Biol. 2005;208:3281-91 pubmed
    ..We conclude that the CT-like peptide Anoga-DH31 is the previously uncharacterised mosquito natriuretic peptide...
  4. Coast G, TeBrugge V, Nachman R, Lopez J, Aldrich J, Lange A, et al. Neurohormones implicated in the control of Malpighian tubule secretion in plant sucking heteropterans: The stink bugs Acrosternum hilare and Nezara viridula. Peptides. 2010;31:468-73 pubmed publisher
    ..prolixus. The antidiuretic activity of Rhopr-CAPA-2 has been linked with terminating the rapid diuresis, but results with stink bugs suggest it is a general feature of heteropteran MT. ..
  5. Coast G, Nachman R, Lopez J. The control of Malpighian tubule secretion in a predacious hemipteran insect, the spined soldier bug Podisus maculiventris (Heteroptera, Pentatomidae). Peptides. 2011;32:493-9 pubmed publisher
    ..On the other hand, the antidiuretic activity of members of the CAP(2b) family in all three bugs is consistent with this being a heteropteran feature rather than a specialism for hematophagy...