Gavin Clowry

Summary

Affiliation: University of Newcastle
Country: UK

Publications

  1. ncbi request reprint Expression of nitric oxide synthase by motor neurones in the spinal cord of the mutant mouse wobbler
    G J Clowry
    University of Newcastle upon Tyne, Department of Child Health, Sir James Spence Institute, Newcastie upon Tyne, UK
    Neurosci Lett 215:177-80. 1996
  2. pmc The corticofugal neuron-associated genes ROBO1, SRGAP1, and CTIP2 exhibit an anterior to posterior gradient of expression in early fetal human neocortex development
    Bui Kar Ip
    Institute of Human Genetics and Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK
    Cereb Cortex 21:1395-407. 2011
  3. pmc Progressive loss of PAX6, TBR2, NEUROD and TBR1 mRNA gradients correlates with translocation of EMX2 to the cortical plate during human cortical development
    Nadhim Bayatti
    Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK
    Eur J Neurosci 28:1449-56. 2008
  4. pmc Renewed focus on the developing human neocortex
    Gavin Clowry
    Institute of Neuroscience, Newcastle University, Framlington Place, Newcastle upon Tyne, UK
    J Anat 217:276-88. 2010
  5. ncbi request reprint The dependence of spinal cord development on corticospinal input and its significance in understanding and treating spastic cerebral palsy
    Gavin J Clowry
    Neural Development, Plasticity and Repair, School of Clinical Medical Sciences and Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK
    Neurosci Biobehav Rev 31:1114-24. 2007
  6. ncbi request reprint The effects of botulinum neurotoxin A induced muscle paresis during a critical period upon muscle and spinal cord development in the rat
    Gavin J Clowry
    Neural Development, Plasticity and Repair, School of Clinical Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
    Exp Neurol 202:456-69. 2006
  7. pmc An immunohistochemical study of the development of sensorimotor components of the early fetal human spinal cord
    Gavin J Clowry
    Neural Development, Plasticity and Repair Group, School of Clinical Medical Sciences, University of Newcastle upon Tyne, UK
    J Anat 207:313-24. 2005
  8. ncbi request reprint Spinal cord plasticity in response to unilateral inhibition of the rat motor cortex during development: changes to gene expression, muscle afferents and the ipsilateral corticospinal projection
    G J Clowry
    Neural Development, Plasticity and Repair Group, School of Clinical Medical Sciences, University of Newcastle, Newcastle upon Tyne, United Kingdom
    Eur J Neurosci 20:2555-66. 2004
  9. ncbi request reprint Brainstem motor nuclei respond differentially to degenerative disease in the mutant mouse wobbler
    G J Clowry
    Neural Development, Plasticity and Repair Group, School of Clinical Medical Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    Neuropathol Appl Neurobiol 30:148-60. 2004
  10. ncbi request reprint Developmental expression of parvalbumin by rat lower cervical spinal cord neurones and the effect of early lesions to the motor cortex
    G J Clowry
    Department of Child Health, University of Newcastle upon Tyne, Sir James Spence Institute, UK
    Brain Res Dev Brain Res 102:197-208. 1997

Collaborators

  • J A Eyre
  • Zoltan Molnar
  • Pasko Rakic
  • C Watts
  • A Guzzetta
  • C Wright
  • Nadhim Bayatti
  • Susan Lindsay
  • Bui Kar Ip
  • T Fisher
  • Aiqing Chen
  • Claire L Gibson
  • C B Dobson
  • C L Gibson
  • Nicholas J Howard
  • Philip Ambrose
  • Nicola Dimambro
  • Li Sun
  • Subrot Sarma
  • Jennifer A Moss
  • Christopher Shaw
  • Demetrius A Vouyiouklis
  • Joseph F H Ward
  • M Smith
  • S Kenwrick
  • F Villagra
  • S Miller
  • D Donnai

Detail Information

Publications19

  1. ncbi request reprint Expression of nitric oxide synthase by motor neurones in the spinal cord of the mutant mouse wobbler
    G J Clowry
    University of Newcastle upon Tyne, Department of Child Health, Sir James Spence Institute, Newcastie upon Tyne, UK
    Neurosci Lett 215:177-80. 1996
    ....
  2. pmc The corticofugal neuron-associated genes ROBO1, SRGAP1, and CTIP2 exhibit an anterior to posterior gradient of expression in early fetal human neocortex development
    Bui Kar Ip
    Institute of Human Genetics and Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK
    Cereb Cortex 21:1395-407. 2011
    ....
  3. pmc Progressive loss of PAX6, TBR2, NEUROD and TBR1 mRNA gradients correlates with translocation of EMX2 to the cortical plate during human cortical development
    Nadhim Bayatti
    Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK
    Eur J Neurosci 28:1449-56. 2008
    ..These data support recent reports that EMX2 but not PAX6 is more directly involved in arealization, highlighting that analysis of human development allows better spatio-temporal resolution than studies in rodents...
  4. pmc Renewed focus on the developing human neocortex
    Gavin Clowry
    Institute of Neuroscience, Newcastle University, Framlington Place, Newcastle upon Tyne, UK
    J Anat 217:276-88. 2010
    ..This review gives a flavour of the recent studies stemming from this renewed focus on the developing human brain...
  5. ncbi request reprint The dependence of spinal cord development on corticospinal input and its significance in understanding and treating spastic cerebral palsy
    Gavin J Clowry
    Neural Development, Plasticity and Repair, School of Clinical Medical Sciences and Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK
    Neurosci Biobehav Rev 31:1114-24. 2007
    ....
  6. ncbi request reprint The effects of botulinum neurotoxin A induced muscle paresis during a critical period upon muscle and spinal cord development in the rat
    Gavin J Clowry
    Neural Development, Plasticity and Repair, School of Clinical Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
    Exp Neurol 202:456-69. 2006
    ..Temporary reduction in activity did not significantly alter muscle afferent development, but temporary blockade of neuromuscular junctions did affect both muscle and motor axon, in the longer term...
  7. pmc An immunohistochemical study of the development of sensorimotor components of the early fetal human spinal cord
    Gavin J Clowry
    Neural Development, Plasticity and Repair Group, School of Clinical Medical Sciences, University of Newcastle upon Tyne, UK
    J Anat 207:313-24. 2005
    ..This investigation contributes towards a timetable for the functional development of human motor control and makes comparisons with well-studied rodent models...
  8. ncbi request reprint Spinal cord plasticity in response to unilateral inhibition of the rat motor cortex during development: changes to gene expression, muscle afferents and the ipsilateral corticospinal projection
    G J Clowry
    Neural Development, Plasticity and Repair Group, School of Clinical Medical Sciences, University of Newcastle, Newcastle upon Tyne, United Kingdom
    Eur J Neurosci 20:2555-66. 2004
    ..Unexpectedly, unilateral inhibition of the motor cortical input did not lead to an expanded muscle afferent input. Instead, this was reduced coincident with development of a bilateral corticospinal innervation...
  9. ncbi request reprint Brainstem motor nuclei respond differentially to degenerative disease in the mutant mouse wobbler
    G J Clowry
    Neural Development, Plasticity and Repair Group, School of Clinical Medical Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    Neuropathol Appl Neurobiol 30:148-60. 2004
    ..Induced CB expression may be neuroprotective but that constitutive expression of PV may not...
  10. ncbi request reprint Developmental expression of parvalbumin by rat lower cervical spinal cord neurones and the effect of early lesions to the motor cortex
    G J Clowry
    Department of Child Health, University of Newcastle upon Tyne, Sir James Spence Institute, UK
    Brain Res Dev Brain Res 102:197-208. 1997
    ..Early cortical lesions disrupt this transient phase of expression but also alter mature patterns of PV localisation. This suggests a critical role for corticospinal pathways in guiding maturation of segmental spinal cord circuitry...
  11. ncbi request reprint Changing pattern of expression of parvalbumin immunoreactivity during human fetal spinal cord development
    G J Clowry
    Developmental Neuroscience Group, Department of Child Health, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom
    J Comp Neurol 423:727-35. 2000
    ..The extent to which expression of PV immunoreactivity can be taken to indicate landmarks in human development will be discussed...
  12. ncbi request reprint N-methyl-D-aspartate receptor blockade during development induces short-term but not long-term changes in c-Jun and parvalbumin expression in the rat cervical spinal cord
    C L Gibson
    Developmental Neuroscience Group, Department of Child Health, University of Newcastle, Newcastle upon Tyne, United Kingdom
    Exp Neurol 170:380-4. 2001
    ....
  13. doi request reprint Elimination of muscle afferent boutons from the cuneate nucleus of the rat medulla during development
    T Fisher
    Institute of Neuroscience, Medical School, Newcastle University, Newcastle upon Tyne, UK
    Neuroscience 161:787-93. 2009
    ..Corticocuneate fibers invade the nucleus during the same period and may influence reorganization of its muscle afferent input, making it another potential site for aberrant reflex development in cerebral palsy...
  14. ncbi request reprint Functional corticospinal projections are established prenatally in the human foetus permitting involvement in the development of spinal motor centres
    J A Eyre
    Developmental Neuroscience Group, Department of Child Health, University of Newcastle upon Tyne, UK
    Brain 123:51-64. 2000
    ..The possibility therefore exists to promote regeneration of disrupted corticospinal projections during the perinatal period with the double benefit of restoring corticospinal connectivity and normal development of spinal motor centres...
  15. ncbi request reprint Abnormal corticospinal function but normal axonal guidance in human L1CAM mutations
    C B Dobson
    Developmental Neuroscience, Department of Child Health, University of Newcastle upon Tyne, UK
    Brain 124:2393-406. 2001
    ..These data support a role for L1CAM in corticospinal tract development in hemizygous males and 'carrier' females, but do not support a critical role for L1CAM in corticospinal axonal guidance...
  16. doi request reprint A comparison of behavioural and histological outcomes of periventricular injection of ibotenic acid in neonatal rats at postnatal days 5 and 7
    Aiqing Chen
    Institute of Neuroscience and School of Clinical Medical Sciences Child Health, Newcastle University, Newcastle upon Tyne, UK
    Brain Res 1201:187-95. 2008
    ..We conclude that IBA induced lesions provide a satisfactory model of PVWMI, particularly when made at P5...
  17. ncbi request reprint The effect on motor cortical neuronal development of focal lesions to the sub-cortical white matter in the neonatal rat: a model for periventricular leukomalacia
    Claire L Gibson
    Brain Development, Plasticity and Repair Group, School of Clinical Medical Sciences Child Health, University of Newcastle upon Tyne, UK
    Int J Dev Neurosci 21:171-82. 2003
    ..Changes in expression of Bax, cJun and non-phosphorylated neurofilaments during normal development are also described...
  18. ncbi request reprint Is hemiplegic cerebral palsy equivalent to amblyopia of the corticospinal system?
    Janet A Eyre
    Department of Developmental Neuroscience, School of Clinical Medical Sciences, University of Newcastle, Newcastle upon Tyne, United Kingdom
    Ann Neurol 62:493-503. 2007
    ....
  19. pmc A molecular neuroanatomical study of the developing human neocortex from 8 to 17 postconceptional weeks revealing the early differentiation of the subplate and subventricular zone
    Nadhim Bayatti
    School of Clinical Medical Sciences, Department of Child Health, Royal Victoria Infirmary, Newcastle upon Tyne, NE1 4LP, UK
    Cereb Cortex 18:1536-48. 2008
    ..PAX6 was extensively expressed in the proliferative zones such that the human outer SVZ contained a large reservoir of PAX6-positive potential progenitor cells...