P G Clifton

Summary

Affiliation: University of Sussex
Country: UK

Publications

  1. ncbi request reprint 5-HT1B receptor knockout mice show a compensatory reduction in 5-HT2C receptor function
    Peter G Clifton
    Experimental Psychology, University of Sussex, Brighton BN1 9QG, UK
    Eur J Neurosci 17:185-90. 2003
  2. ncbi request reprint Little and often: ingestive behavior patterns following hippocampal lesions in rats
    P G Clifton
    School of Biological Sciences, University of Sussex, Brighton, England
    Behav Neurosci 112:502-11. 1998
  3. ncbi request reprint Meal patterning in rodents: psychopharmacological and neuroanatomical studies
    P G Clifton
    Laboratory of Experimental Psychology, University of Sussex, Brighton, UK
    Neurosci Biobehav Rev 24:213-22. 2000
  4. ncbi request reprint Similarities in the action of Ro 60-0175, a 5-HT2C receptor agonist and d-fenfluramine on feeding patterns in the rat
    P G Clifton
    Laboratory of Experimental Psychology, University of Sussex, Brighton, UK
    Psychopharmacology (Berl) 152:256-67. 2000
  5. ncbi request reprint Serotonin 1B and 2C receptor interactions in the modulation of feeding behaviour in the mouse
    G L Dalton
    Department of Psychology, Sussex University, Brighton, BN1 9QG, UK
    Psychopharmacology (Berl) 185:45-57. 2006
  6. ncbi request reprint mCPP-induced hyperactivity in 5-HT2C receptor mutant mice is mediated by activation of multiple 5-HT receptor subtypes
    G L Dalton
    Department of Psychology, Sussex University, Brighton BN1 9QG, UK
    Neuropharmacology 46:663-71. 2004
  7. ncbi request reprint Behavioural evidence that d-fenfluramine-induced anorexia in the rat is not mediated by the 5-HT1A receptor subtype
    S P Vickers
    Laboratory of Experimental Psychology, University of Sussex, Brighton, UK
    Psychopharmacology (Berl) 125:168-75. 1996
  8. ncbi request reprint Partial reversal of fluoxetine anorexia by the 5-HT antagonist metergoline
    M D Lee
    Laboratory of Experimental Psychology, University of Sussex, Brighton, UK
    Psychopharmacology (Berl) 107:359-64. 1992
  9. ncbi request reprint Reduced satiating effect of d-fenfluramine in serotonin 5-HT(2C) receptor mutant mice
    S P Vickers
    Laboratory of Experimental Psychology, University of Sussex, Brighton, East Sussex, UK
    Psychopharmacology (Berl) 143:309-14. 1999
  10. doi request reprint Reduced activity at the 5-HT(2C) receptor enhances reversal learning by decreasing the influence of previously non-rewarded associations
    S R O Nilsson
    School of Psychology, University of Sussex, Brighton, BN1 9QH, UK
    Psychopharmacology (Berl) 224:241-54. 2012

Collaborators

Detail Information

Publications14

  1. ncbi request reprint 5-HT1B receptor knockout mice show a compensatory reduction in 5-HT2C receptor function
    Peter G Clifton
    Experimental Psychology, University of Sussex, Brighton BN1 9QG, UK
    Eur J Neurosci 17:185-90. 2003
    ..These results demonstrate that compensatory adaptations to the constitutive loss of 5-HT1B receptors may be an important determinant of the altered response of 5-HT1B KO mice to a variety of pharmacological challenges...
  2. ncbi request reprint Little and often: ingestive behavior patterns following hippocampal lesions in rats
    P G Clifton
    School of Biological Sciences, University of Sussex, Brighton, England
    Behav Neurosci 112:502-11. 1998
    ..The data are discussed in terms of changes in behavioral switching or a possible interoceptive agnosia following hippocampal damage...
  3. ncbi request reprint Meal patterning in rodents: psychopharmacological and neuroanatomical studies
    P G Clifton
    Laboratory of Experimental Psychology, University of Sussex, Brighton, UK
    Neurosci Biobehav Rev 24:213-22. 2000
    ..These structures may play a role in the organisation of meal patterning...
  4. ncbi request reprint Similarities in the action of Ro 60-0175, a 5-HT2C receptor agonist and d-fenfluramine on feeding patterns in the rat
    P G Clifton
    Laboratory of Experimental Psychology, University of Sussex, Brighton, UK
    Psychopharmacology (Berl) 152:256-67. 2000
    ..Activation of 5-HT2C receptors is thought to enhance satiety and to mediate the action of the prototypical anorectic drug d-fenfluramine...
  5. ncbi request reprint Serotonin 1B and 2C receptor interactions in the modulation of feeding behaviour in the mouse
    G L Dalton
    Department of Psychology, Sussex University, Brighton, BN1 9QG, UK
    Psychopharmacology (Berl) 185:45-57. 2006
    ..To examine the functional relationship between 5-HT1B receptors (5-HT1B-R) and 5-HT2C receptors (5-HT2C-R) in the control of food intake...
  6. ncbi request reprint mCPP-induced hyperactivity in 5-HT2C receptor mutant mice is mediated by activation of multiple 5-HT receptor subtypes
    G L Dalton
    Department of Psychology, Sussex University, Brighton BN1 9QG, UK
    Neuropharmacology 46:663-71. 2004
    ..By contrast, mCPP-induced hyperactivity depends on the inactivation of a separate 5-HT2C receptor population and is mediated by 5-HT2A and 5-HT1B receptor activation...
  7. ncbi request reprint Behavioural evidence that d-fenfluramine-induced anorexia in the rat is not mediated by the 5-HT1A receptor subtype
    S P Vickers
    Laboratory of Experimental Psychology, University of Sussex, Brighton, UK
    Psychopharmacology (Berl) 125:168-75. 1996
    ..The implications of these results to the utility of the behavioural satiety sequence as a measure of postprandial satiety are discussed...
  8. ncbi request reprint Partial reversal of fluoxetine anorexia by the 5-HT antagonist metergoline
    M D Lee
    Laboratory of Experimental Psychology, University of Sussex, Brighton, UK
    Psychopharmacology (Berl) 107:359-64. 1992
    ..We conclude that fluoxetine reduces food intake by enhancing satiety through a serotonergic dependent mechanism but reduces feeding rate through a separate mechanism, whose neurochemical basis remains to be established...
  9. ncbi request reprint Reduced satiating effect of d-fenfluramine in serotonin 5-HT(2C) receptor mutant mice
    S P Vickers
    Laboratory of Experimental Psychology, University of Sussex, Brighton, East Sussex, UK
    Psychopharmacology (Berl) 143:309-14. 1999
    ..d-Fenfluramine stimulates the release of serotonin (5-HT) and is a potent inhibitor of the re-uptake of 5-HT into nerve terminals. Administration of d-fenfluramine suppresses food intake in both animals and humans...
  10. doi request reprint Reduced activity at the 5-HT(2C) receptor enhances reversal learning by decreasing the influence of previously non-rewarded associations
    S R O Nilsson
    School of Psychology, University of Sussex, Brighton, BN1 9QH, UK
    Psychopharmacology (Berl) 224:241-54. 2012
    ..Successful reversal learning can be reduced to two dissociable cognitive mechanisms, to dissipate associations of previous positive (opposed by perseverance) and negative (opposed by learned non-reward) valence...
  11. ncbi request reprint Monoamine receptors in the regulation of feeding behaviour and energy balance
    P G Clifton
    Department of Psychology, Sussex University, Brighton, BN1 9QG, UK
    CNS Neurol Disord Drug Targets 5:293-312. 2006
    ..We conclude that compounds interacting with 5-HT(2C), 5-HT(6) and histamine H(3) receptors may be of particular interest as specific drug development targets for the treatment of appetite disturbance in obesity...
  12. doi request reprint Intra-accumbens baclofen, but not muscimol, mimics the effects of food withdrawal on feeding behaviour
    K G T Pulman
    Schools of Psychology, University of Sussex, Brighton, UK
    Pharmacol Biochem Behav 97:156-62. 2010
    ....
  13. ncbi request reprint Effects of dopamine D1 and dopamine D2 antagonists on the free feeding and drinking patterns of rats
    P G Clifton
    Laboratory of Experimental Psychology, University of Sussex, Brighton, United Kingdom
    Behav Neurosci 105:272-81. 1991
    ..D1 receptors, in contrast, are of greater importance in controlling water intake...
  14. doi request reprint Alpha1- and alpha2-containing GABAA receptor modulation is not necessary for benzodiazepine-induced hyperphagia
    H V Morris
    Department of Psychology, University of Sussex, Falmer, Brighton, UK
    Appetite 52:675-83. 2009
    ..These observations, together with evidence against the involvement of alpha5-containing GABA(A) receptors, suggest that alpha3-containing receptors mediate BZ-induced hyperphagia in the mouse...