Hannah F Clarke

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. pmc Orbitofrontal dopamine depletion upregulates caudate dopamine and alters behavior via changes in reinforcement sensitivity
    H F Clarke
    Departments of Physiology, Development and Neuroscience, Behavioral and Clinical Neuroscience Institute, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 34:7663-76. 2014
  2. ncbi request reprint Cognitive inflexibility after prefrontal serotonin depletion is behaviorally and neurochemically specific
    H F Clarke
    Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge, CB2 3EB, UK
    Cereb Cortex 17:18-27. 2007
  3. pmc Lesions of the medial striatum in monkeys produce perseverative impairments during reversal learning similar to those produced by lesions of the orbitofrontal cortex
    Hannah F Clarke
    Department of Experimental Psychology and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge CB23EB, United Kingdom
    J Neurosci 28:10972-82. 2008
  4. pmc Dopamine, but not serotonin, regulates reversal learning in the marmoset caudate nucleus
    Hannah F Clarke
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 31:4290-7. 2011
  5. ncbi request reprint Cognitive inflexibility after prefrontal serotonin depletion
    H F Clarke
    Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge, UK
    Science 304:878-80. 2004
  6. pmc Differential contributions of the primate ventrolateral prefrontal and orbitofrontal cortex to serial reversal learning
    Rafal Rygula
    Department of Experimental Psychology and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 30:14552-9. 2010
  7. ncbi request reprint Prefrontal serotonin depletion affects reversal learning but not attentional set shifting
    H F Clarke
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 25:532-8. 2005
  8. ncbi request reprint The role of the orbitofrontal cortex and medial striatum in the regulation of prepotent responses to food rewards
    M S Man
    Department of Physiology, Development and Neuroscience, University of Cambridge, UK
    Cereb Cortex 19:899-906. 2009

Detail Information

Publications8

  1. pmc Orbitofrontal dopamine depletion upregulates caudate dopamine and alters behavior via changes in reinforcement sensitivity
    H F Clarke
    Departments of Physiology, Development and Neuroscience, Behavioral and Clinical Neuroscience Institute, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 34:7663-76. 2014
    ..These results demonstrate that OFC dopamine depletion is sufficient to induce striatal hyperdopaminergia and changes in reinforcement learning relevant to schizophrenia. ..
  2. ncbi request reprint Cognitive inflexibility after prefrontal serotonin depletion is behaviorally and neurochemically specific
    H F Clarke
    Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge, CB2 3EB, UK
    Cereb Cortex 17:18-27. 2007
    ....
  3. pmc Lesions of the medial striatum in monkeys produce perseverative impairments during reversal learning similar to those produced by lesions of the orbitofrontal cortex
    Hannah F Clarke
    Department of Experimental Psychology and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge CB23EB, United Kingdom
    J Neurosci 28:10972-82. 2008
    ....
  4. pmc Dopamine, but not serotonin, regulates reversal learning in the marmoset caudate nucleus
    Hannah F Clarke
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 31:4290-7. 2011
    ....
  5. ncbi request reprint Cognitive inflexibility after prefrontal serotonin depletion
    H F Clarke
    Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge, UK
    Science 304:878-80. 2004
    ....
  6. pmc Differential contributions of the primate ventrolateral prefrontal and orbitofrontal cortex to serial reversal learning
    Rafal Rygula
    Department of Experimental Psychology and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 30:14552-9. 2010
    ..Together, these data demonstrate the heterogeneous but interrelated involvement of primate OFC and VLPFC in the performance of serial reversal learning...
  7. ncbi request reprint Prefrontal serotonin depletion affects reversal learning but not attentional set shifting
    H F Clarke
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 25:532-8. 2005
    ....
  8. ncbi request reprint The role of the orbitofrontal cortex and medial striatum in the regulation of prepotent responses to food rewards
    M S Man
    Department of Physiology, Development and Neuroscience, University of Cambridge, UK
    Cereb Cortex 19:899-906. 2009
    ..These findings identify the critical contribution of the OFC and MS in the regulation of responding by affective cues...