Lisa Cipolotti

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi request reprint Long-term retrograde amnesia...the crucial role of the hippocampus
    L Cipolotti
    Department of Clinical Neuropsychology, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
    Neuropsychologia 39:151-72. 2001
  2. ncbi request reprint A combined neuropsychological and neuroimaging study of topographical and non-verbal memory in semantic dementia
    L Cipolotti
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, Queen Square, WC1N 3BG, London, UK
    Neuropsychologia 41:1148-59. 2003
  3. ncbi request reprint Impaired allocentric spatial memory underlying topographical disorientation
    Neil Burgess
    Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London WC1N 3AR, UK
    Rev Neurosci 17:239-51. 2006
  4. doi request reprint Distinct neuropsychological profiles correspond to distribution of cortical thinning in inherited prion disease caused by insertional mutation
    K Alner
    National Prion Clinic, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK
    J Neurol Neurosurg Psychiatry 83:109-14. 2012
  5. pmc The middle house or the middle floor: bisecting horizontal and vertical mental number lines in neglect
    Marinella Cappelletti
    Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London WC1N 3AR, UK
    Neuropsychologia 45:2989-3000. 2007
  6. ncbi request reprint Fractionation of visual memory: evidence from a case with multiple neurodevelopmental impairments
    L Cipolotti
    Department of Clinical Neuropsychology, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK
    Neuropsychologia 37:455-65. 1999
  7. ncbi request reprint Recollection and familiarity in dense hippocampal amnesia: a case study
    Lisa Cipolotti
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
    Neuropsychologia 44:489-506. 2006
  8. ncbi request reprint Amnesia and the hippocampus
    Lisa Cipolotti
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, London, UK
    Curr Opin Neurol 19:593-8. 2006
  9. doi request reprint The role of the thalamus in amnesia: a tractography, high-resolution MRI and neuropsychological study
    L Cipolotti
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom
    Neuropsychologia 46:2745-58. 2008
  10. ncbi request reprint The impact of deep dysgraphia on graphemic buffer disorders
    L Cipolotti
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, London, UK
    Neurocase 10:405-19. 2004

Detail Information

Publications82

  1. ncbi request reprint Long-term retrograde amnesia...the crucial role of the hippocampus
    L Cipolotti
    Department of Clinical Neuropsychology, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
    Neuropsychologia 39:151-72. 2001
    ..Our results are compatible with the view that retrograde amnesia is both extensive and ungraded when the damage is limited to the hippocampus...
  2. ncbi request reprint A combined neuropsychological and neuroimaging study of topographical and non-verbal memory in semantic dementia
    L Cipolotti
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, Queen Square, WC1N 3BG, London, UK
    Neuropsychologia 41:1148-59. 2003
    ..The combination of the neuropsychological and neuroimaging approaches may provide insights into the functional-anatomy of memory while having clinical utility for the assessment of residual brain tissue...
  3. ncbi request reprint Impaired allocentric spatial memory underlying topographical disorientation
    Neil Burgess
    Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London WC1N 3AR, UK
    Rev Neurosci 17:239-51. 2006
    ..The specificity of our test indicates a new way of assessing topographical disorientation, with possible application to the assessment of progressive dementias such as Alzheimer's disease...
  4. doi request reprint Distinct neuropsychological profiles correspond to distribution of cortical thinning in inherited prion disease caused by insertional mutation
    K Alner
    National Prion Clinic, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK
    J Neurol Neurosurg Psychiatry 83:109-14. 2012
    ..Here we report for the first time the neuropsychological and clinical assessments in these two groups...
  5. pmc The middle house or the middle floor: bisecting horizontal and vertical mental number lines in neglect
    Marinella Cappelletti
    Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London WC1N 3AR, UK
    Neuropsychologia 45:2989-3000. 2007
    ....
  6. ncbi request reprint Fractionation of visual memory: evidence from a case with multiple neurodevelopmental impairments
    L Cipolotti
    Department of Clinical Neuropsychology, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK
    Neuropsychologia 37:455-65. 1999
    ..These findings indicate that different domains of the visual memory system can be fractionated developmentally. In particular, it demonstrates that topographical memory can develop independently from other aspects of visual memory...
  7. ncbi request reprint Recollection and familiarity in dense hippocampal amnesia: a case study
    Lisa Cipolotti
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
    Neuropsychologia 44:489-506. 2006
    ..It also plays an appreciable role in familiarity processes for these stimuli. However, recollection and familiarity of human faces appear not to depend on this region...
  8. ncbi request reprint Amnesia and the hippocampus
    Lisa Cipolotti
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, London, UK
    Curr Opin Neurol 19:593-8. 2006
    ..Severe amnesia is usually observed following bilateral hippocampal pathology. This review addresses the precise role of the hippocampus and related medial temporal lobe structures in amnesia...
  9. doi request reprint The role of the thalamus in amnesia: a tractography, high-resolution MRI and neuropsychological study
    L Cipolotti
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom
    Neuropsychologia 46:2745-58. 2008
    ..This finding raises the possibility that fractionation of familiarity and recollection to separate thalamic nuclei may not fully capture the role of thalamic sub-regions in memory function...
  10. ncbi request reprint The impact of deep dysgraphia on graphemic buffer disorders
    L Cipolotti
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, London, UK
    Neurocase 10:405-19. 2004
    ..Thus, DA's written spelling was characterized by both deep dysgraphic and graphemic output buffer effects. It is proposed that this pattern of performance represents a new"putative functional syndrome."..
  11. doi request reprint Conceptual proposition selection and the LIFG: neuropsychological evidence from a focal frontal group
    Gail Robinson
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK
    Neuropsychologia 48:1652-63. 2010
    ..These results provide evidence that the LIFG is crucial for selecting among multiple competing conceptual propositions for language generation...
  12. pmc Social and emotional functions in three patients with medial frontal lobe damage including the anterior cingulate cortex
    Amee Baird
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, London, UK
    Cogn Neuropsychiatry 11:369-88. 2006
    ..The aim of this study was to explore social and emotional functions in patients with medial frontal damage including the anterior cingulate cortex (ACC)...
  13. doi request reprint IQ and the fronto-temporal cortex in bipolar disorder
    Leticia GutiƩrrez-Galve
    UCL Institute of Neurology, Queen Square, London, United Kingdom
    J Int Neuropsychol Soc 18:370-4. 2012
    ..The pattern of cortico-cognitive associations in BPI and BPII patients merits further consideration...
  14. doi request reprint Confabulation: damage to a specific inferior medial prefrontal system
    Martha S Turner
    Institute of Cognitive Neuroscience, University College London, London, UK
    Cortex 44:637-48. 2008
    ..Performance on tests of memory and executive functioning showed considerable variability. Although a degree of memory impairment does seem necessary, performance on traditional executive tests is less helpful in explaining confabulation...
  15. ncbi request reprint Cognitive functioning after medial frontal lobe damage including the anterior cingulate cortex: a preliminary investigation
    Amee Baird
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, London, UK
    Brain Cogn 60:166-75. 2006
    ..We speculate that our findings may be compatible with the view that the ACC integrates cognitive processing with autonomic functioning to guide behaviour...
  16. doi request reprint Numbers and time doubly dissociate
    Marinella Cappelletti
    Institute of Cognitive Neuroscience, University College London, London, UK
    Neuropsychologia 49:3078-92. 2011
    ....
  17. pmc Frontal subregions mediating Elevator Counting task performance
    Sarah E MacPherson
    Institute of Cognitive Neuroscience, University College London, London, UK
    Neuropsychologia 48:3679-82. 2010
    ..Research suggests that patients with medial lesions are susceptible to competition from task irrelevant schema; whereas the left lateral group in the current study may fail to keep track of the tones already presented...
  18. pmc The hippocampus is required for short-term topographical memory in humans
    Tom Hartley
    Institute of Cognitive Neuroscience, UCL, London, UK
    Hippocampus 17:34-48. 2007
    ....
  19. pmc Impairments in proverb interpretation following focal frontal lobe lesions
    Patrick Murphy
    National Hospital for Neurology and Neurosurgery, Box 37 Queen Square, London WC1N 3BG, UK
    Neuropsychologia 51:2075-86. 2013
    ..We found no correlation between scores on the PIT and on the fluid intelligence task. Overall our results suggest that specific regions of the frontal lobes contribute to the performance on the PIT. ..
  20. doi request reprint Changing associations between cognitive impairment and imaging in multiple sclerosis as the disease progresses
    Sophia A Penny
    UCL Institute of Neurology, Queen Square, London, UK
    J Neuropsychiatry Clin Neurosci 25:134-40. 2013
    ..Our findings suggest that gray-matter pathology, reflected by atrophy measurements, becomes increasingly important in determining cognition as MS progresses...
  21. pmc MRI-visible perivascular spaces: relationship to cognition and small vessel disease MRI markers in ischaemic stroke and TIA
    Robert Hurford
    Stroke Research Group, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology and the National Hospital for Neurology and Neurosurgery, London, UK
    J Neurol Neurosurg Psychiatry 85:522-5. 2014
    ..We investigated the association between PVS and cognitive impairment, and other MRI markers of small vessel disease, in a patient cohort of ischaemic stroke/transient ischaemic attack (TIA) referrals...
  22. doi request reprint Diffusion MRI-based cortical complexity alterations associated with executive function in multiple sclerosis
    Nils Muhlert
    NMR Unit, Department of Neuroinflammation, UCL Institute of Neurology, London, UK
    J Magn Reson Imaging 38:54-63. 2013
    ....
  23. pmc Effect of frontal lobe lesions on the recollection and familiarity components of recognition memory
    Sarah E MacPherson
    Institute of Cognitive Neuroscience, University College London, London, UK
    Neuropsychologia 46:3124-32. 2008
    ..Both analyses led to similar conclusions where only the familiarity component of recognition memory was impaired in frontal patients compared to healthy controls whilst the recollection-type (or variance ratio) processes remained intact...
  24. ncbi request reprint The effect of adult-acquired hippocampal damage on memory retrieval: an fMRI study
    Eleanor A Maguire
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK
    Neuroimage 27:146-52. 2005
    ..We speculate that it may relate to the age at which hippocampal damage occurred reflecting plasticity within the developing brain, or to cognitive differences between VC, the developmental amnesic patient, and the control subjects...
  25. ncbi request reprint Monitoring cognitive changes: psychometric properties of six cognitive tests
    Chris M Bird
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
    Br J Clin Psychol 43:197-210. 2004
    ..In this study we document, for six cognitive tests: test-retest reliabilities, practice effects, reliable change (RC) indices corrected for practice, and the impact of premorbid IQ and age...
  26. doi request reprint Strictly lobar microbleeds are associated with executive impairment in patients with ischemic stroke or transient ischemic attack
    Simone M Gregoire
    Department of Brain Repair and Rehabilitation, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, United Kingdom
    Stroke 44:1267-72. 2013
    ..We, therefore, investigated the cognitive impact of CMBs in a cohort of patients with ischemic stroke or transient ischemic attack...
  27. ncbi request reprint Cognitive functioning in orthostatic hypotension due to pure autonomic failure
    Hannah C Heims
    Dept of Neuropsychology, Box 37, National Hospital for Neurology and Neurosurgery, Queen Square, London, WC1N 3BG, UK
    Clin Auton Res 16:113-20. 2006
    ..However, a failure in integrated bodily arousal responses during cognitive behaviours may also contribute to some of the observed deficits...
  28. ncbi request reprint Preserved knowledge of maps of countries: implications for the organization of semantic memory
    Antonio Incisa della Rocchetta
    Department of Neuropsychology, The National Hospital for Neurology and Neurosurgery, London, UK
    Neurocase 10:249-64. 2004
    ..The evolutionary model needs to envisage the possibility that some categories of knowledge, such as countries, may not be prewired, but learned during ontogenetic development...
  29. doi request reprint Spontaneous confabulation, temporal context confusion and reality monitoring: a study of three patients with anterior communicating artery aneurysms
    Martha S Turner
    Institute of Cognitive Neuroscience, University College London, London, United Kingdom
    J Int Neuropsychol Soc 16:984-94. 2010
    ....
  30. pmc Bringing the cognitive estimation task into the 21st century: normative data on two new parallel forms
    Sarah E MacPherson
    Institute of Cognitive Neuroscience, University College London, London, United Kingdom Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, London, United Kingdom
    PLoS ONE 9:e92554. 2014
    ..This study provides normative data for parallel forms of the CET for adults which are also suitable for assessing frontal lobe dysfunction on more than one occasion without practice effects. ..
  31. doi request reprint Domain-specific trends in cognitive impairment after acute ischaemic stroke
    Robert Hurford
    Stroke Research Group, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, London, UK
    J Neurol 260:237-41. 2013
    ..The domain-specific improvement patterns may help to inform long-term rehabilitation plans, which should not be based solely on cognitive assessments undertaken within the first month after stroke...
  32. ncbi request reprint Cognitive dysfunction in patients with cerebral microbleeds on T2*-weighted gradient-echo MRI
    David J Werring
    Stroke Research Group, Department of Clinical Neurology, Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK
    Brain 127:2265-75. 2004
    ..These findings have implications for the diagnosis of stroke patients with cognitive impairment, and for the appropriate use of antihypertensive and antiplatelet treatments in these patients...
  33. ncbi request reprint Bipolar I and bipolar II disorder: cognition and emotion processing
    Mary Summers
    NMR Research Unit, Institute of Neurology, University College London, London, UK
    Psychol Med 36:1799-809. 2006
    ..The same applies to deficits in emotion processing known to be present in BP...
  34. ncbi request reprint Unconscious processing of Arabic numerals in unilateral neglect
    Marinella Cappelletti
    Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London WC1N 3AR, UK
    Neuropsychologia 44:1999-2006. 2006
    ..e. quantity). These results show that patients with left unilateral neglect can still semantically process Arabic numerals unconsciously...
  35. ncbi request reprint Fractionation of memory in medial temporal lobe amnesia
    Chris M Bird
    Institute of Cognitive Neuroscience, 17 Queen Square, WC1N 3AR London, UK
    Neuropsychologia 45:1160-71. 2007
    ..Face recognition memory may be adequately subserved by areas outside of the hippocampus...
  36. ncbi request reprint The utility of the recognition memory test and the graded naming test for monitoring neurological patients
    Chris M Bird
    The Institute of Cognitive Neuroscience, University College London, UK
    Br J Clin Psychol 46:223-34. 2007
    ..In this study we document: test-retest reliability (TRR), group changes in performance and measures of intra-subject variability for two commonly used cognitive tests...
  37. ncbi request reprint Qualitatively different memory impairments across frontal lobe subgroups
    Martha S Turner
    Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London WC1N 3AR, UK
    Neuropsychologia 45:1540-52. 2007
    ..We offer two explanations for the pattern of performance in the Right Lateral group: failure of a right lateralised error detection and checking system, or an impairment in the active uncued initiation of a supervisory operation...
  38. ncbi request reprint Pure progressive amnesia and the APPV717G mutation
    William D Knight
    Department of Neurodegenerative Diseases, Dementia Research Centre, Institute of Neurology, University College London, UK
    Alzheimer Dis Assoc Disord 23:410-4. 2009
    ..The mean annual hippocampal atrophy rate, determined by volumetric magnetic resonance imaging was intermediate between values previously associated with cognitively normal individuals and those with sporadic Alzheimer disease...
  39. pmc Dissociations and interactions between time, numerosity and space processing
    Marinella Cappelletti
    Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London WC1N 3AR, UK
    Neuropsychologia 47:2732-48. 2009
    ..These data suggest a partly shared mechanism between time, numbers and space which may be involved in magnitude processing or may be recruited to perform cognitive operations on magnitude dimensions...
  40. ncbi request reprint Selective impairments for addition, subtraction and multiplication. implications for the organisation of arithmetical facts
    N J van Harskamp
    Neuropsychology Department, National Hospital for Neurology and Neurosurgery, London, UK
    Cortex 37:363-88. 2001
    ..We will argue that our findings are problematic for Dehaene's model and in good accord with McCloskey's view...
  41. ncbi request reprint Auditory temporal processing deficits in patients with insular stroke
    D E Bamiou
    Neuro Otology Department, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
    Neurology 67:614-9. 2006
    ..To assess central auditory function in a series of patients with stroke of the insula and adjacent areas...
  42. doi request reprint Cognitive and social cognitive functioning in spinocerebellar ataxia : a preliminary characterization
    P Garrard
    Institute of Cognitive Neuroscience, 17 Queen Square, London, WC1N 3AR, UK
    J Neurol 255:398-405. 2008
    ....
  43. doi request reprint A preliminary characterisation of cognition and social cognition in spinocerebellar ataxia types 2, 1, and 7
    N Sokolovsky
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK
    Behav Neurol 23:17-29. 2010
    ..Moreover, these patients may also have social cognition impairments. Overall, we suggest that there is a degree of heterogeneity in the types of cognitive and social cognitive impairments in SCA patients...
  44. ncbi request reprint Selective sparing of verb naming in a case of severe Alzheimer's disease
    G Robinson
    National Hospital for Neurology and Neurosurgery London, Department of Clinical Neuropsychology, UK
    Cortex 35:443-50. 1999
    ..The implications for the notion of an intrinsic vulnerability of verb naming in AD and for the current knowledge of anatomical correlates of noun/verb processing are discussed...
  45. ncbi request reprint Social and motivational functioning is not critically dependent on feedback of autonomic responses: neuropsychological evidence from patients with pure autonomic failure
    H C Heims
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, Box 37, Queen Square, London WC1N 3BG, UK
    Neuropsychologia 42:1979-88. 2004
    ....
  46. ncbi request reprint Impaired social response reversal. A case of 'acquired sociopathy'
    R J Blair
    Institute of Cognitive Neuroscience and Department of Psychology, University College London, UK
    Brain 123:1122-41. 2000
    ..Moreover, it is proposed that the orbitofrontal cortex may be implicated specifically either in the generation of these expectations or the use of these expectations to suppress inappropriate behaviour...
  47. ncbi request reprint Knight's move thinking? Mild cognitive impairment in a chess player
    H A Archer
    The Dementia Research Centre, The National Hospital for Neurology and Neurosurgery, London, UK
    Neurocase 11:26-31. 2005
    ....
  48. ncbi request reprint Fractionation of visual memory: agency detection and its impairment in autism
    R J R Blair
    Institute of Cognitive Neuroscience, University College London, Alexandra House, 17 Queen Square, WC1H 3AR, London, UK
    Neuropsychologia 40:108-18. 2002
    ..The data is interpreted in terms of reduced sensitivity to agency cues in individuals with autism and general information processing capacity...
  49. ncbi request reprint The selective preservation of colour naming in semantic dementia
    G Robinson
    Department of Clinical Neuropsychology, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
    Neurocase 7:65-75. 2001
    ..These findings are discussed in the light of current theoretical accounts of category-specific effects and the possible contribution of imageability to this selective preservation of colours...
  50. ncbi request reprint Distinct neural systems for the encoding and recognition of topography and faces
    E A Maguire
    Wellcome Department of Cognitive Neurology, Institute of Neurology, University College London, 12 Queen Square, London, WC1N 3BG, United Kingdom
    Neuroimage 13:743-50. 2001
    ....
  51. ncbi request reprint Patterns of temporal lobe atrophy in semantic dementia and Alzheimer's disease
    D Chan
    Department of Clinical Neurology, Institute of Neurology, The National Hospital for Neurology and Neurosurgery, London, UK
    Ann Neurol 49:433-42. 2001
    ..In addition, the pattern of atrophy in semantic dementia suggests that semantic memory is subserved by anterior temporal lobe structures, within which the middle and inferior temporal gyri may play a key role...
  52. ncbi request reprint A decade of pre-diagnostic assessment in a case of familial Alzheimer's disease: tracking progression from asymptomatic to MCI and dementia
    A K Godbolt
    Dementia Research Group, Institute of Neurology, Queen Square, London, UK
    Neurocase 11:56-64. 2005
    ..Longitudinal MRI, neuropsychological and clinical data are presented over the decade preceding this man's diagnosis, through the asymptomatic and prodromal preludes to his presentation with MCI and on to eventual conversion to AD...
  53. ncbi request reprint Does the left inferior parietal lobule contribute to multiplication facts?
    Natasja J van Harskamp
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, London, UK
    Cortex 41:742-52. 2005
    ..2002). The previously suggested crucial role of the SMG/AG in the retrieval of simple multiplication facts is therefore poorly supported (Cohen et al., 2000; Lee, 2000)...
  54. doi request reprint Cerebral microbleeds and vascular cognitive impairment
    David J Werring
    Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, London WC1N 3BG, UK
    J Neurol Sci 299:131-5. 2010
    ..CMBs may therefore play a role in understanding the underlying mechanisms of vascular cognitive impairment, in diagnosis, and in assessing its severity and prognosis; this review considers recent evidence on this topic...
  55. ncbi request reprint Dynamic aphasia in progressive supranuclear palsy: a deficit in generating a fluent sequence of novel thought
    Gail Robinson
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
    Neuropsychologia 44:1344-60. 2006
    ..We interpret our patients' impairment as being underpinned by a deficit in one set of mechanisms involved in discourse generation; namely the generation of a fluent sequence of novel thought...
  56. ncbi request reprint Test-retest reliability, practice effects and reliable change indices for the recognition memory test
    Chris M Bird
    Department of Neuropsychology, The National Hospital for Neurology and Neurosurgery Group, London, UK
    Br J Clin Psychol 42:407-25. 2003
    ..In this study, we document for the first time test-retest reliabilities, practice effects, and Reliable Change (RC) indices for this test...
  57. pmc Mapping the onset and progression of atrophy in familial frontotemporal lobar degeneration
    J C Janssen
    Dementia Research Group, Institute of Neurology, Queen Square, London WC1N 3BG, UK
    J Neurol Neurosurg Psychiatry 76:162-8. 2005
    ..Frontotemporal lobar degeneration (FTLD) may be inherited as an autosomal dominant disease. Studying patients "at risk" for developing FTLD can provide insights into the earliest onset and evolution of the disease...
  58. ncbi request reprint Clinical-anatomical correlation in a selective phonemic speech production impairment
    A J Larner
    Dementia Research Group, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK
    J Neurol Sci 219:23-9. 2004
    ....
  59. ncbi request reprint Human cingulate cortex and autonomic control: converging neuroimaging and clinical evidence
    Hugo D Critchley
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, London WC1N 3BG, UK
    Brain 126:2139-52. 2003
    ..Thus, converging neuroimaging and clinical findings suggest that ACC function mediates context-driven modulation of bodily arousal states...
  60. ncbi request reprint Attributional style in a case of Cotard delusion
    Ryan McKay
    Department of Neuropsychology, The National Hospital for Neurology and Neurosurgery, London, UK
    Conscious Cogn 16:349-59. 2007
    ..The potential brain basis of Cotard delusion is discussed...
  61. ncbi request reprint Memory function after resolution of post-traumatic amnesia
    A Baird
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, London, UK
    Brain Inj 19:811-7. 2005
    ....
  62. pmc Identification without naming: a functional neuroimaging study of an anomic patient
    M Gorno-Tempini
    Wellcome Department of Cognitive Neurology, Institute of Neurology, 12 Queen Square, London WC1N 3BG, UK
    J Neurol Neurosurg Psychiatry 70:397-400. 2001
    ..Both the patient and the controls activated the left ATC when famous stimuli were compared with non-famous stimuli. This result supports the hypothesis of a predominantly semantic function of the left ATC...
  63. doi request reprint Early imaging predicts later cognitive impairment in primary progressive multiple sclerosis
    S Penny
    Department of Neuroinflammation, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK
    Neurology 74:545-52. 2010
    ..Using a cohort/case control methodology, we explore the ability of MRI abnormalities, including those in the normal-appearing brain tissue, to predict future cognitive dysfunction in PPMS...
  64. ncbi request reprint Cognitive and social impairments in patients with superficial siderosis
    N J van Harskamp
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, London, UK
    Brain 128:1082-92. 2005
    ..They are consistent with the recently proposed role of the cerebellum as a modulator of cognitive, social and emotional functions...
  65. ncbi request reprint Clinical features of frontotemporal dementia due to the intronic tau 10(+16) mutation
    J C Janssen
    Dementia Research Group, Institute of Neurology, London, UK
    Neurology 58:1161-8. 2002
    ..To describe the clinical features of nine British families with neuropathologically verified frontotemporal dementia (FTD) due to the intronic tau exon 10(+16) mutation...
  66. pmc The neuropsychology of variant CJD: a comparative study with inherited and sporadic forms of prion disease
    R J Cordery
    Dementia Research Group, The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
    J Neurol Neurosurg Psychiatry 76:330-6. 2005
    ....
  67. doi request reprint Cognitive impairment in multiple sclerosis can be predicted by imaging early in the disease
    M Summers
    Institute of Neurology, University College London, Queen Square, London, UK
    J Neurol Neurosurg Psychiatry 79:955-8. 2008
    ..Cognitive impairment is common in multiple sclerosis (MS) and adds significantly to the burden of the disease. The ability to predict future cognitive impairment from imaging obtained at disease onset has not been investigated...
  68. ncbi request reprint Cognitive dysfunction and depression in Fabry disease: a systematic review
    Fay E Bolsover
    Charles Dent Metabolic Unit, National Hospital for Neurology and Neurosurgery, 8 11 Queen Square, Internal Mailbox 92, London, WC1N 3BG, UK
    J Inherit Metab Dis 37:177-87. 2014
    ..However, the prevalence and pattern of associated cognitive dysfunction is not well understood...
  69. ncbi request reprint Delineating the sites and progression of in vivo atrophy in multiple system atrophy using fluid-registered MRI
    Jonathan M Schott
    Dementia Research Group, Institute of Neurology, London, United Kingdom
    Mov Disord 18:955-8. 2003
    ..The in vivo findings were consistent with those found at postmortem, including significant supratentorial atrophy concurrent with an unusual degree of cognitive impairment for MSA...
  70. ncbi request reprint Are multiplication facts implemented by the left supramarginal and angular gyri?
    Natasja J van Harskamp
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
    Neuropsychologia 40:1786-93. 2002
    ..In addition, this case contradicts the predicted association between subtraction and quantity manipulation, proposed by Dehaene's triple-code model [Cortex 33 (1997) 219]...
  71. doi request reprint Cognitive, biochemical, and imaging profile of patients suffering from idiopathic normal pressure hydrocephalus
    Andrew Tarnaris
    Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, United Kingdom
    Alzheimers Dement 7:501-8. 2011
    ..It has still not been clearly established whether the cognitive deficits of idiopathic normal pressure hydrocephalus (iNPH) are caused by a disturbance in cerebrospinal fluid (CSF) dynamics or an underlying metabolic disturbance...
  72. ncbi request reprint Cognitive impairment in relapsing-remitting multiple sclerosis can be predicted by imaging performed several years earlier
    Mm Summers
    NMR Research Unit, Institute of Neurology, University College London, London, UK
    Mult Scler 14:197-204. 2008
    ..Neuroaxonal loss is likely to affect commissural and association fibres that subserve the cognitive processes impaired in MS...
  73. ncbi request reprint MRS shows abnormalities before symptoms in familial Alzheimer disease
    A K Godbolt
    Dementia Research Centre, Institute of Neurology, University College of London, London, UK
    Neurology 66:718-22. 2006
    ..Presenilin 1 (PS1) and amyloid precursor protein (APP) mutation carriers have a nearly 100% risk of developing AD and may be studied prior to symptom onset...
  74. ncbi request reprint To play 'B' but not to say 'B': selective loss of letter names
    A Bevan
    Institute of Cognitive Neuroscience, University College London, London, UK
    Neurocase 9:118-28. 2003
    ..By contrast, instrumental sightreading and matching of written letters and single notes were both well preserved. This complex pattern of impairments can be explained in terms of a selective deficit in the letter name system...
  75. ncbi request reprint Autopsy-confirmed familial early-onset Alzheimer disease caused by the l153V presenilin 1 mutation
    J C Janssen
    Dementia Research Group, Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, England
    Arch Neurol 58:953-8. 2001
    ..CONCLUSIONS: The PSEN1 L153V mutation lies in the main mutation cluster of PSEN1 in the second transmembrane domain. It causes early-onset FAD with clinical features similar to those of other reported FAD pedigrees...
  76. ncbi request reprint A second family with familial AD and the V717L APP mutation has a later age at onset
    A K Godbolt
    Dementia Research Centre, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK
    Neurology 66:611-2. 2006
  77. ncbi request reprint The hippocampus and remote autobiographical memory
    Lisa Cipolotti
    Lancet Neurol 4:792-3. 2005
  78. ncbi request reprint The natural history of Alzheimer disease: a longitudinal presymptomatic and symptomatic study of a familial cohort
    Alison K Godbolt
    Dementia Research Group, Institute of Neurology, London, England
    Arch Neurol 61:1743-8. 2004
    ..Knowledge of the evolution of cognitive deficits in Alzheimer disease is important for our understanding of disease progression. Previous reports, however, have either lacked detail or have not covered the presymptomatic stages...
  79. ncbi request reprint Mechanisms underlying perseveration in aphasia: evidence from a single case study
    Stephen J Gotts
    Department of Psychology Baker Hall, Carnegie Mellon University and Center for the Neural Basis of Cognition, Pittsburgh, PA 15213, USA
    Neuropsychologia 40:1930-47. 2002
    ..7 (1994) 13] is capable of accounting for all aspects of E.B.'s perseverative behavior...
  80. ncbi request reprint Sporadic and familial dementia with ubiquitin-positive tau-negative inclusions: clinical features of one histopathological abnormality underlying frontotemporal lobar degeneration
    Alison K Godbolt
    Dementia Research Centre, Institute of Neurology, University College London, England
    Arch Neurol 62:1097-101. 2005
    ..Familial disease occurs in up to 50% of frontotemporal lobar degeneration cases. One of several underlying histopathological abnormalities is of ubiquitin-positive tau-negative inclusions, similar to those in motor neuron disease...
  81. ncbi request reprint Diagnosis, treatment, and analysis of long-term outcomes in idiopathic normal-pressure hydrocephalus
    Andrew Tarnaris
    Neurosurgery 60:E208; author reply E208. 2007
  82. ncbi request reprint Coiling versus clipping for the treatment of aneurysmal subarachnoid hemorrhage: a longitudinal investigation into cognitive outcome
    Duncan Frazer
    Department of Clinical Neuropsychology, and Therapy and Rehabilitation Services, The National Hospital for Neurology and Neurosurgery London, England
    Neurosurgery 60:434-41; discussion 441-2. 2007
    ..The aim of the present study was to provide a prospective, longitudinal investigation into cognitive function in patients with aneurysmal subarachnoid hemorrhage treated with either neurosurgical clipping or endovascular coiling...