Research Topics
| Lorenzo A CingolaniSummaryAffiliation: University College London Country: UK Publications
| Collaborators
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Detail Information
Publications
Activity-dependent regulation of synaptic AMPA receptor composition and abundance by beta3 integrinsLorenzo A Cingolani
MRC Laboratory for Molecular Cell Biology and Cell Biology Unit, University College London, Gower Street, London WC1E 6BT, UK
Neuron 58:749-62. 2008..Our findings demonstrate a key role for integrins in the feedback regulation of excitatory synaptic strength...
Differential involvement of beta3 integrin in pre- and postsynaptic forms of adaptation to chronic activity deprivationLorenzo A Cingolani
MRC Laboratory for Molecular Cell Biology and Cell Biology Unit, UCL, Gower Street, WC1E 6BT London, UK
Neuron Glia Biol 4:179-87. 2008..Our findings define the differential involvement of beta3 integrin in two forms of synaptic homeostasis...
β3 integrin interacts directly with GluA2 AMPA receptor subunit and regulates AMPA receptor expression in hippocampal neuronsKarine Pozo
Medical Research Council Laboratory for Molecular Cell Biology and Cell Biology Unit, University College London, London WC1E 6BT, United Kingdom
Proc Natl Acad Sci U S A 109:1323-8. 2012..Our findings identify an integrin family member, β3, as a direct interactor of an AMPAR subunit and provide molecular insights into how this cell-adhesion protein regulates the composition of cell-surface AMPARs...
Stabilising influence: integrins in regulation of synaptic plasticityAndrew B McGeachie
Medical Research Council Laboratory for Molecular Cell Biology and Cell Biology Unit, University College London, Gower Street, London WC1E6BT, UK
Neurosci Res 70:24-9. 2011..Moreover, recent studies have implicated integrins in AMPAR trafficking and glycine receptor lateral diffusion, highlighting their multifaceted functions at the synapse...
beta-Catenin regulates excitatory postsynaptic strength at hippocampal synapsesTakashi Okuda
Medical Research Council Laboratory for Molecular Cell Biology and Cell Biology Unit, Department of Pharmacology, University College London, Gower Street, London WC1E 6BT, United Kingdom
Proc Natl Acad Sci U S A 104:13479-84. 2007..Collectively, these findings suggest that the cadherin-beta-catenin complex is an integral component of synaptic strength regulation and plays a basic role in coupling synapse function and spine morphology...
Actin in action: the interplay between the actin cytoskeleton and synaptic efficacyLorenzo A Cingolani
MRC Laboratory for Molecular Cell Biology and MRC Cell Biology Unit, University College London, Gower Street, London, WC1E 6BT, UK
Nat Rev Neurosci 9:344-56. 2008..The aim of this Review is to highlight some of the recent progress in elucidating the role of the actin cytoskeleton in synaptic function...
The use of nanodiamond monolayer coatings to promote the formation of functional neuronal networksAgnes Thalhammer
Laboratory for Molecular Pharmacology, NPP, University College London, Gower Street, London, WC1E 6BT, UK
Biomaterials 31:2097-104. 2010..ND layering provides an excellent growth substrate on various materials for functional neuronal networks and bypasses the necessity of protein coating, which promises great potential for chronic medical implants...
Developmental regulation of small-conductance Ca2+-activated K+ channel expression and function in rat Purkinje neuronsLorenzo A Cingolani
Max-Planck-Institute for Experimental Medicine, , Germany
J Neurosci 22:4456-67. 2002..These results provide the first evidence of the developmental regulation and function of SK channels in central neurons...
