Lorenza Ciani

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi WNTs in the vertebrate nervous system: from patterning to neuronal connectivity
    Lorenza Ciani
    Department of Anatomy and Developmental Biology, University College London, London WC1E 6BT, UK
    Nat Rev Neurosci 6:351-62. 2005
  2. ncbi c-Jun N-terminal kinase (JNK) cooperates with Gsk3beta to regulate Dishevelled-mediated microtubule stability
    Lorenza Ciani
    Department of Anatomy and Developmental Biology, University College London, London, UK
    BMC Cell Biol 8:27. 2007
  3. ncbi Signaling across the synapse: a role for Wnt and Dishevelled in presynaptic assembly and neurotransmitter release
    Azlina Ahmad-Annuar
    Department of Anatomy and Developmental Biology, University College London, London WC1E 6BT, England, UK
    J Cell Biol 174:127-39. 2006
  4. ncbi From neuronal activity to the actin cytoskeleton: a role for CaMKKs and betaPIX in spine morphogenesis
    Lorenza Ciani
    Department of Anatomy and Developmental Biology, University College London, University Street, London WC1E 6BT, UK
    Neuron 57:3-4. 2008
  5. ncbi A divergent canonical WNT-signaling pathway regulates microtubule dynamics: dishevelled signals locally to stabilize microtubules
    Lorenza Ciani
    Department of Biological Sciences, Imperial College London, London SW7 2AZ, England, UK
    J Cell Biol 164:243-53. 2004
  6. ncbi Wnt regulates axon behavior through changes in microtubule growth directionality: a new role for adenomatous polyposis coli
    Silvia A Purro
    Research Department of Cell and Developmental Biology, University College London, London WC1E 6BT, United Kingdom
    J Neurosci 28:8644-54. 2008

Collaborators

Detail Information

Publications6

  1. ncbi WNTs in the vertebrate nervous system: from patterning to neuronal connectivity
    Lorenza Ciani
    Department of Anatomy and Developmental Biology, University College London, London WC1E 6BT, UK
    Nat Rev Neurosci 6:351-62. 2005
    ..This knowledge provides a framework for the study of the mechanisms by which WNTs regulate diverse neuronal functions. Manipulation of the WNT pathways could provide new strategies for nerve regeneration and neuronal circuit modulation...
  2. ncbi c-Jun N-terminal kinase (JNK) cooperates with Gsk3beta to regulate Dishevelled-mediated microtubule stability
    Lorenza Ciani
    Department of Anatomy and Developmental Biology, University College London, London, UK
    BMC Cell Biol 8:27. 2007
    ..A divergent Wnt-Dvl canonical pathway which bifurcates downstream of Gsk3beta regulates MT dynamics...
  3. ncbi Signaling across the synapse: a role for Wnt and Dishevelled in presynaptic assembly and neurotransmitter release
    Azlina Ahmad-Annuar
    Department of Anatomy and Developmental Biology, University College London, London WC1E 6BT, England, UK
    J Cell Biol 174:127-39. 2006
    ..These findings demonstrate that Wnts signal across the synapse on Dvl-expressing presynaptic terminals to regulate synaptic assembly and suggest a potential novel function for Wnts in neurotransmitter release...
  4. ncbi From neuronal activity to the actin cytoskeleton: a role for CaMKKs and betaPIX in spine morphogenesis
    Lorenza Ciani
    Department of Anatomy and Developmental Biology, University College London, University Street, London WC1E 6BT, UK
    Neuron 57:3-4. 2008
    ..In this issue of Neuron, Saneyoshi et al. identify a new signaling complex containing CaMKK/CaMKI/betaPIX/Rac that regulates the morphogenesis of spines in an activity-dependent manner...
  5. ncbi A divergent canonical WNT-signaling pathway regulates microtubule dynamics: dishevelled signals locally to stabilize microtubules
    Lorenza Ciani
    Department of Biological Sciences, Imperial College London, London SW7 2AZ, England, UK
    J Cell Biol 164:243-53. 2004
    ..Our data indicate a bifurcation in the so-called canonical WNT-signaling pathway to regulate microtubule stability...
  6. ncbi Wnt regulates axon behavior through changes in microtubule growth directionality: a new role for adenomatous polyposis coli
    Silvia A Purro
    Research Department of Cell and Developmental Biology, University College London, London WC1E 6BT, United Kingdom
    J Neurosci 28:8644-54. 2008
    ..Consistently, short hairpin RNA knockdown of APC mimics Wnt3a function. Together, our findings define APC as a key Wnt signaling target in the regulation of microtubule growth direction...