Affiliation: University of Southampton
- Enumeration and phenotypic assessment of human plasmacytoid and myeloid dendritic cells in whole bloodFerdousi Chowdhury
Cancer Sciences Division, CRUK Clinical Centre, Somers Cancer Research Building, University of Southampton, Southampton General Hospital, Southampton, SO16 6YD, England
Cytometry A 77:328-37. 2010..We have shown that this DC enumeration flow cytometry panel is a robust analysis system that allows the flexibility of including activation markers...
- Development, validation and application of ELISAs for pharmacokinetic and HACA assessment of a chimeric anti-CD40 monoclonal antibody in human serumF Chowdhury
Cancer Sciences Division, CRUK Clinical Centre, University of Southampton, Southampton, SO16 6YD, UK
J Immunol Methods 363:1-8. 2010..Each assay has been successfully translated for use in a clinical trial with adequate quality controls and acceptance criteria set for monitoring consistency and performance...
- Fit for purpose? A case study: validation of immunological endpoint assays for the detection of cellular and humoral responses to anti-tumour DNA fusion vaccinesAnn Mander
Cancer Sciences Division, School of Medicine, Southampton General Hospital, University of Southampton, Tremona Road, Southampton, UK
Cancer Immunol Immunother 58:789-800. 2009....
- From research to regulated: challenges in transferring methodsFerdousi Chowdhury
CRUK Clinical Centre, Somers Cancer Research Building, University of Southampton, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, UK
Bioanalysis 1:285-91. 2009..We discuss the advantages and limitations for such end point assays in early Phase clinical trials...