- Changes in rat n-3 and n-6 fatty acid composition during pregnancy are associated with progesterone concentrations and hepatic FADS2 expressionC E Childs
Human Development and Health Academic Unit, University of Southampton, Southampton SO16 6YD, United Kingdom
Prostaglandins Leukot Essent Fatty Acids 86:141-7. 2012..05). Changes in progesterone and oestradiol during pregnancy may promote the synthesis of LC PUFA via increased FADS2 expression...
- The polyunsaturated fatty acid composition of hepatic and plasma lipids differ by both sex and dietary fat intake in ratsCaroline E Childs
Institute of Human Nutrition and Developmental Origins of Health and Disease Division, School of Medicine, University of Southampton, Southampton SO16 6YD, UK
J Nutr 140:245-50. 2010..Together, these findings show that sex is an important determinant of the effect of variations in fat and fatty acid intake on LCPUFA status, which may have implications for recommendations for fat and fatty acid intake in humans...
- Maternal diet during pregnancy has tissue-specific effects upon fetal fatty acid composition and alters fetal immune parametersCaroline E Childs
Department of Food and Nutritional Sciences, The University of Reading, Whiteknights, P O Box 226, Reading, Berkshire RG6 6AP, United Kingdom
Prostaglandins Leukot Essent Fatty Acids 83:179-84. 2010..These data indicate that dietary ALA supplementation may confer some of the benefits of LC (n-3) PUFA during pregnancy. This should be examined in suitably designed human studies...
- Gender differences in the n-3 fatty acid content of tissuesCaroline E Childs
School of Medicine, University of Southampton, Southampton SO16 6YD, UK
Proc Nutr Soc 67:19-27. 2008..These findings suggest that sex hormones act to modify plasma and tissue n-3 PUFA content, possibly by altering the expression of desaturase and elongase enzymes in the liver, which is currently under investigation...