Zhengming Chen

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi Indications for early aspirin use in acute ischemic stroke : A combined analysis of 40 000 randomized patients from the chinese acute stroke trial and the international stroke trial. On behalf of the CAST and IST collaborative groups
    Z M Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, Oxford, UK
    Stroke 31:1240-9. 2000
  2. ncbi China Kadoorie Biobank of 0.5 million people: survey methods, baseline characteristics and long-term follow-up
    Zhengming Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
    Int J Epidemiol 40:1652-66. 2011
  3. ncbi Early intravenous then oral metoprolol in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial
    Z M Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Richard Doll Building, Old Road Campus, Oxford OX3 7LF, UK
    Lancet 366:1622-32. 2005
  4. ncbi Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial
    Z M Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Richard Doll Building, Old Road Campus, Oxford OX3 7LF, UK
    Lancet 366:1607-21. 2005
  5. ncbi Body mass index and mortality from ischaemic heart disease in a lean population: 10 year prospective study of 220,000 adult men
    Zhengming Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Radcliffe Infirmary, University of Oxford, UK
    Int J Epidemiol 35:141-50. 2006
  6. ncbi Smoking and cardiovascular disease
    Zhengming Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, University of Oxford, UK
    Semin Vasc Med 2:243-52. 2002
  7. ncbi Cohort profile: the Kadoorie Study of Chronic Disease in China (KSCDC)
    Zhengming Chen
    Clinical Trial Service Unit (CTSU, Richard Doll Building, Old Road Campus, Roosevelt Drive, Oxford OX3 7LF, UK
    Int J Epidemiol 34:1243-9. 2005
  8. ncbi Smoking and liver cancer in China: case-control comparison of 36,000 liver cancer deaths vs. 17,000 cirrhosis deaths
    Zheng Ming Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Radcliffe Infirmary, University of Oxford, United Kingdom
    Int J Cancer 107:106-12. 2003
  9. ncbi Alcohol drinking and overall and cause-specific mortality in China: nationally representative prospective study of 220,000 men with 15 years of follow-up
    Ling Yang
    Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford, UK
    Int J Epidemiol 41:1101-13. 2012
  10. ncbi Body mass index and mortality in China: a 15-year prospective study of 220 000 men
    Zhengming Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
    Int J Epidemiol 41:472-81. 2012

Detail Information

Publications22

  1. ncbi Indications for early aspirin use in acute ischemic stroke : A combined analysis of 40 000 randomized patients from the chinese acute stroke trial and the international stroke trial. On behalf of the CAST and IST collaborative groups
    Z M Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, Oxford, UK
    Stroke 31:1240-9. 2000
    ..However, some uncertainty remains about the effects of early aspirin in particular categories of patient with acute stroke...
  2. ncbi China Kadoorie Biobank of 0.5 million people: survey methods, baseline characteristics and long-term follow-up
    Zhengming Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
    Int J Epidemiol 40:1652-66. 2011
    ..Large blood-based prospective studies can provide reliable assessment of the complex interplay of lifestyle, environmental and genetic factors as determinants of chronic disease...
  3. ncbi Early intravenous then oral metoprolol in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial
    Z M Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Richard Doll Building, Old Road Campus, Oxford OX3 7LF, UK
    Lancet 366:1622-32. 2005
    ....
  4. ncbi Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial
    Z M Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Richard Doll Building, Old Road Campus, Oxford OX3 7LF, UK
    Lancet 366:1607-21. 2005
    ..The antiplatelet agent clopidogrel adds to the benefit of aspirin in acute coronary syndromes without ST-segment elevation, but its effects in patients with ST-elevation MI were unclear...
  5. ncbi Body mass index and mortality from ischaemic heart disease in a lean population: 10 year prospective study of 220,000 adult men
    Zhengming Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Radcliffe Infirmary, University of Oxford, UK
    Int J Epidemiol 35:141-50. 2006
    ..Substantial uncertainty remains, however, about the relationship between BMI and IHD in populations with lower BMI levels...
  6. ncbi Smoking and cardiovascular disease
    Zhengming Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, University of Oxford, UK
    Semin Vasc Med 2:243-52. 2002
    ..Although the smoking prevalence has declined dramatically over the last few decades in many Western populations, it is increasing rapidly in most developing countries, with an emerging epidemic of tobacco related death...
  7. ncbi Cohort profile: the Kadoorie Study of Chronic Disease in China (KSCDC)
    Zhengming Chen
    Clinical Trial Service Unit (CTSU, Richard Doll Building, Old Road Campus, Roosevelt Drive, Oxford OX3 7LF, UK
    Int J Epidemiol 34:1243-9. 2005
  8. ncbi Smoking and liver cancer in China: case-control comparison of 36,000 liver cancer deaths vs. 17,000 cirrhosis deaths
    Zheng Ming Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Radcliffe Infirmary, University of Oxford, United Kingdom
    Int J Cancer 107:106-12. 2003
    ..09, 95% CI 0.94-1.25). These associations indicate that tobacco is currently responsible for about 50,000 liver cancer deaths each year in China, chiefly among men with chronic HBV infection...
  9. ncbi Alcohol drinking and overall and cause-specific mortality in China: nationally representative prospective study of 220,000 men with 15 years of follow-up
    Ling Yang
    Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford, UK
    Int J Epidemiol 41:1101-13. 2012
    ..Regular alcohol drinking contributes both favourably and adversely to health in the Western populations, but its effects on overall and cause-specific mortality in China are still poorly understood...
  10. ncbi Body mass index and mortality in China: a 15-year prospective study of 220 000 men
    Zhengming Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
    Int J Epidemiol 41:472-81. 2012
    ....
  11. ncbi Body mass index and chronic obstructive pulmonary disease-related mortality: a nationally representative prospective study of 220,000 men in China
    Ling Yang
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, University of Oxford, Oxford, UK
    Int J Epidemiol 39:1027-36. 2010
    ..Substantial uncertainty remains about the relationship in populations with lower mean BMI levels, and about the relevance to it of the effects of smoking or of reverse causality...
  12. ncbi Body mass index and mortality from lung cancer in smokers and nonsmokers: a nationally representative prospective study of 220,000 men in China
    Ling Yang
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, University of Oxford, Oxford, United Kingdom
    Int J Cancer 125:2136-43. 2009
    ..In this relatively lean Chinese male population, low BMI was strongly associated with increased risk of lung cancer only among current smokers...
  13. ncbi Esophageal cancer and body mass index: results from a prospective study of 220,000 men in China and a meta-analysis of published studies
    Margaret Smith
    Clinical Trial Service Unit, University of Oxford, United Kingdom
    Int J Cancer 122:1604-10. 2008
    ..Together, these data provide reliable evidence that in many populations low BMI is associated with an increased risk of squamous cell carcinoma of the esophagus...
  14. ncbi Seasonal variation in blood pressure and its relationship with outdoor temperature in 10 diverse regions of China: the China Kadoorie Biobank
    Sarah Lewington
    Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, UK
    J Hypertens 30:1383-91. 2012
    ..Substantial uncertainty exists, however, about the strength of the relationship in other populations and its relevance to age, adiposity, medical treatment, climate and housing conditions...
  15. ncbi Physical activity and sedentary leisure time and their associations with BMI, waist circumference, and percentage body fat in 0.5 million adults: the China Kadoorie Biobank study
    Huaidong Du
    Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
    Am J Clin Nutr 97:487-96. 2013
    ..Few large studies in China have investigated total physical activity and sedentary leisure time and their associations with adiposity...
  16. ncbi Reproductive history, oral contraceptive use, and the risk of ischemic and hemorrhagic stoke in a cohort study of middle-aged Swedish women
    Ling Yang
    Clinical Trials Service Unit, Richard Doll Building, Oxford, UK
    Stroke 40:1050-8. 2009
    ..Controversy persists as to whether oral contraceptive (OC) use and reproductive history play a role in the etiology of stroke, particularly ischemic stroke. Our aim was to investigate this question in a cohort of middle-aged Swedish women...
  17. ncbi The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial
    Colin Baigent
    Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford, UK
    Lancet 377:2181-92. 2011
    ..The SHARP trial aimed to assess the efficacy and safety of the combination of simvastatin plus ezetimibe in such patients...
  18. ncbi Body mass index, blood pressure, and mortality from stroke: a nationally representative prospective study of 212,000 Chinese men
    Maigeng Zhou
    Disease Surveillance Points Central Office, Chinese Center for Disease Control, Beijing, People s Republic of China
    Stroke 39:753-9. 2008
    ..Despite previous investigations, substantial uncertainty remains about the relation between body mass index (BMI) and stroke, especially in populations with a relatively low BMI but a high stroke rate...
  19. ncbi Cidea-deficient mice have lean phenotype and are resistant to obesity
    Zhihong Zhou
    Laboratories of Apoptosis Regulation, Institute of Molecular and Cell Biology, 30 Medical Dr, Singapore 117609, Singapore
    Nat Genet 35:49-56. 2003
    ..Our data thus indicate a role for Cidea in regulating energy balance and adiposity...
  20. ncbi Antithrombotic therapy in patients with any form of intracranial haemorrhage: a systematic review of the available controlled studies
    Sarah L Keir
    Department of Clinical Neurosciences, Western General Hospital NHS Trust, Edinburgh, UK
    Cerebrovasc Dis 14:197-206. 2002
    ..Antithrombotic agents should be avoided where possible in patients with acute intracerebral haemorrhage...
  21. ncbi Poverty and chronic diseases in Asia: challenges and opportunities
    Prabhat Jha
    Centre for Global Health Research, St. Michael's Hospital, University of Toronto, Toronto, Ont
    CMAJ 177:1059-62. 2007
  22. ncbi Global burden of cardiovascular disease
    John E Sanderson
    Heart 93:1175. 2007