Zhengming Chen

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi request reprint Indications for early aspirin use in acute ischemic stroke : A combined analysis of 40 000 randomized patients from the chinese acute stroke trial and the international stroke trial. On behalf of the CAST and IST collaborative groups
    Z M Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, Oxford, UK
    Stroke 31:1240-9. 2000
  2. ncbi request reprint Smoking and liver cancer in China: case-control comparison of 36,000 liver cancer deaths vs. 17,000 cirrhosis deaths
    Zheng Ming Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Radcliffe Infirmary, University of Oxford, United Kingdom
    Int J Cancer 107:106-12. 2003
  3. pmc Exhaled carbon monoxide and its associations with smoking, indoor household air pollution and chronic respiratory diseases among 512,000 Chinese adults
    Qiuli Zhang
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, University of Oxford, Oxford, UK, School of Public Health, Peking University Health Science Center, Beijing, China, Chinese Academy of Medical Sciences, Dong Cheng District, Beijing, China, China National Center for Food Safety Risk Assessment, Chaoyang District, Beijing, China, Licang Center for Disease Control and Prevention, Qingdao, Shandong, China, Heilongjiang Center for Disease Control and Prevention, Harbin, Heilongjiang, China, Meilan Center for Disease Control and Prevention, Haikou, Hainan, China, Guangxi Center for Disease Control and Prevention, Nanning, Guangxi, China and Liuyang Center for Disease Control and Prevention, Changsha, Hunan, China
    Int J Epidemiol 42:1464-75. 2013
  4. pmc China Kadoorie Biobank of 0.5 million people: survey methods, baseline characteristics and long-term follow-up
    Zhengming Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
    Int J Epidemiol 40:1652-66. 2011
  5. ncbi request reprint Early intravenous then oral metoprolol in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial
    Z M Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Richard Doll Building, Old Road Campus, Oxford OX3 7LF, UK
    Lancet 366:1622-32. 2005
  6. ncbi request reprint Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial
    Z M Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Richard Doll Building, Old Road Campus, Oxford OX3 7LF, UK
    Lancet 366:1607-21. 2005
  7. ncbi request reprint Body mass index and mortality from ischaemic heart disease in a lean population: 10 year prospective study of 220,000 adult men
    Zhengming Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Radcliffe Infirmary, University of Oxford, UK
    Int J Epidemiol 35:141-50. 2006
  8. ncbi request reprint Smoking and cardiovascular disease
    Zhengming Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, University of Oxford, UK
    Semin Vasc Med 2:243-52. 2002
  9. ncbi request reprint Cohort profile: the Kadoorie Study of Chronic Disease in China (KSCDC)
    Zhengming Chen
    Clinical Trial Service Unit CTSU, Richard Doll Building, Old Road Campus, Roosevelt Drive, Oxford OX3 7LF, UK
    Int J Epidemiol 34:1243-9. 2005
  10. pmc Alcohol consumption in 0.5 million people from 10 diverse regions of China: prevalence, patterns and socio-demographic and health-related correlates
    Iona Y Millwood
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Nuffield Department of Population Health, University of Oxford, UK
    Int J Epidemiol 42:816-27. 2013

Detail Information

Publications28

  1. ncbi request reprint Indications for early aspirin use in acute ischemic stroke : A combined analysis of 40 000 randomized patients from the chinese acute stroke trial and the international stroke trial. On behalf of the CAST and IST collaborative groups
    Z M Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, Oxford, UK
    Stroke 31:1240-9. 2000
    ..However, some uncertainty remains about the effects of early aspirin in particular categories of patient with acute stroke...
  2. ncbi request reprint Smoking and liver cancer in China: case-control comparison of 36,000 liver cancer deaths vs. 17,000 cirrhosis deaths
    Zheng Ming Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Radcliffe Infirmary, University of Oxford, United Kingdom
    Int J Cancer 107:106-12. 2003
    ..09, 95% CI 0.94-1.25). These associations indicate that tobacco is currently responsible for about 50,000 liver cancer deaths each year in China, chiefly among men with chronic HBV infection...
  3. pmc Exhaled carbon monoxide and its associations with smoking, indoor household air pollution and chronic respiratory diseases among 512,000 Chinese adults
    Qiuli Zhang
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, University of Oxford, Oxford, UK, School of Public Health, Peking University Health Science Center, Beijing, China, Chinese Academy of Medical Sciences, Dong Cheng District, Beijing, China, China National Center for Food Safety Risk Assessment, Chaoyang District, Beijing, China, Licang Center for Disease Control and Prevention, Qingdao, Shandong, China, Heilongjiang Center for Disease Control and Prevention, Harbin, Heilongjiang, China, Meilan Center for Disease Control and Prevention, Haikou, Hainan, China, Guangxi Center for Disease Control and Prevention, Nanning, Guangxi, China and Liuyang Center for Disease Control and Prevention, Changsha, Hunan, China
    Int J Epidemiol 42:1464-75. 2013
    ..Relatively little is known about its determinants in China despite the population having a high prevalence of smoking and use of biomass/coal...
  4. pmc China Kadoorie Biobank of 0.5 million people: survey methods, baseline characteristics and long-term follow-up
    Zhengming Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
    Int J Epidemiol 40:1652-66. 2011
    ..Large blood-based prospective studies can provide reliable assessment of the complex interplay of lifestyle, environmental and genetic factors as determinants of chronic disease...
  5. ncbi request reprint Early intravenous then oral metoprolol in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial
    Z M Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Richard Doll Building, Old Road Campus, Oxford OX3 7LF, UK
    Lancet 366:1622-32. 2005
    ....
  6. ncbi request reprint Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial
    Z M Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Richard Doll Building, Old Road Campus, Oxford OX3 7LF, UK
    Lancet 366:1607-21. 2005
    ..The antiplatelet agent clopidogrel adds to the benefit of aspirin in acute coronary syndromes without ST-segment elevation, but its effects in patients with ST-elevation MI were unclear...
  7. ncbi request reprint Body mass index and mortality from ischaemic heart disease in a lean population: 10 year prospective study of 220,000 adult men
    Zhengming Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Radcliffe Infirmary, University of Oxford, UK
    Int J Epidemiol 35:141-50. 2006
    ..Substantial uncertainty remains, however, about the relationship between BMI and IHD in populations with lower BMI levels...
  8. ncbi request reprint Smoking and cardiovascular disease
    Zhengming Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, University of Oxford, UK
    Semin Vasc Med 2:243-52. 2002
    ..Although the smoking prevalence has declined dramatically over the last few decades in many Western populations, it is increasing rapidly in most developing countries, with an emerging epidemic of tobacco related death...
  9. ncbi request reprint Cohort profile: the Kadoorie Study of Chronic Disease in China (KSCDC)
    Zhengming Chen
    Clinical Trial Service Unit CTSU, Richard Doll Building, Old Road Campus, Roosevelt Drive, Oxford OX3 7LF, UK
    Int J Epidemiol 34:1243-9. 2005
  10. pmc Alcohol consumption in 0.5 million people from 10 diverse regions of China: prevalence, patterns and socio-demographic and health-related correlates
    Iona Y Millwood
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Nuffield Department of Population Health, University of Oxford, UK
    Int J Epidemiol 42:816-27. 2013
    ..Drinking alcohol has a long tradition in Chinese culture. However, data on the prevalence and patterns of alcohol consumption in China, and its main correlates, are limited...
  11. ncbi request reprint Alcohol drinking and overall and cause-specific mortality in China: nationally representative prospective study of 220,000 men with 15 years of follow-up
    Ling Yang
    Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford, UK
    Int J Epidemiol 41:1101-13. 2012
    ..Regular alcohol drinking contributes both favourably and adversely to health in the Western populations, but its effects on overall and cause-specific mortality in China are still poorly understood...
  12. doi request reprint Peak flow as a predictor of cause-specific mortality in China: results from a 15-year prospective study of ~170,000 men
    Margaret Smith
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Nuffield Department of Clinical Medicine, University of Oxford, UK
    Int J Epidemiol 42:803-15. 2013
    ....
  13. ncbi request reprint Body mass index and mortality in China: a 15-year prospective study of 220 000 men
    Zhengming Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
    Int J Epidemiol 41:472-81. 2012
    ....
  14. doi request reprint Body mass index and chronic obstructive pulmonary disease-related mortality: a nationally representative prospective study of 220,000 men in China
    Ling Yang
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, University of Oxford, Oxford, UK
    Int J Epidemiol 39:1027-36. 2010
    ..Substantial uncertainty remains about the relationship in populations with lower mean BMI levels, and about the relevance to it of the effects of smoking or of reverse causality...
  15. ncbi request reprint Physical activity and sedentary leisure time and their associations with BMI, waist circumference, and percentage body fat in 0.5 million adults: the China Kadoorie Biobank study
    Huaidong Du
    Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
    Am J Clin Nutr 97:487-96. 2013
    ..Few large studies in China have investigated total physical activity and sedentary leisure time and their associations with adiposity...
  16. ncbi request reprint Body mass index and mortality from lung cancer in smokers and nonsmokers: a nationally representative prospective study of 220,000 men in China
    Ling Yang
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, University of Oxford, Oxford, United Kingdom
    Int J Cancer 125:2136-43. 2009
    ..In this relatively lean Chinese male population, low BMI was strongly associated with increased risk of lung cancer only among current smokers...
  17. ncbi request reprint Esophageal cancer and body mass index: results from a prospective study of 220,000 men in China and a meta-analysis of published studies
    Margaret Smith
    Clinical Trial Service Unit, University of Oxford, United Kingdom
    Int J Cancer 122:1604-10. 2008
    ..Together, these data provide reliable evidence that in many populations low BMI is associated with an increased risk of squamous cell carcinoma of the esophagus...
  18. ncbi request reprint Temporal trends of main reproductive characteristics in ten urban and rural regions of China: the China Kadoorie Biobank study of 300 000 women
    Sarah Lewington
    Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford, UK, School of Public Health, Peking University Health Science Center, Beijing, China, Chinese Academy of Medical Sciences, Dong Cheng District, Beijing, China, Chinese National Center for Food Safety Risk Assessment, Beijing, China, Nangang Center for Disease Control, Haerbin, Heilongjiang, China, Jiangsu Centre for Disease Control, Nanjing, Jiangsu, China, Huixian Centre for Disease Control, Huixian, Hennan, China, Gansu Centre for Disease Control, Lanzhou, Gansu, China and Liuzhou Centre for Disease Control, Liuzhou, Guangxi, China
    Int J Epidemiol 43:1252-62. 2014
    ..Chinese women's reproductive patterns have changed significantly over the past several decades. However, relatively little is known about the pace and characteristics of these changes either overall or by region and socioeconomic status...
  19. doi request reprint Seasonal variation in blood pressure and its relationship with outdoor temperature in 10 diverse regions of China: the China Kadoorie Biobank
    Sarah Lewington
    Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, UK
    J Hypertens 30:1383-91. 2012
    ..Substantial uncertainty exists, however, about the strength of the relationship in other populations and its relevance to age, adiposity, medical treatment, climate and housing conditions...
  20. pmc Prevalence and correlates of airflow obstruction in ∼317,000 never-smokers in China
    Margaret Smith
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, University of Oxford, Oxford, UK
    Eur Respir J 44:66-77. 2014
    ..Associations were similar for males. AFO is prevalent in Chinese never-smokers, particularly among those with low socioeconomic status or prior tuberculosis, and in rural males. ..
  21. pmc Use of drug treatment for secondary prevention of cardiovascular disease in urban and rural communities of China: China Kadoorie Biobank Study of 0.5 million people
    YiPing Chen
    Clinical Trial Service Unit and Epidemiological Studies Unit CTSU, Nuffield Department of Population Health, University of Oxford, Oxford, UK Electronic address
    Int J Cardiol 172:88-95. 2014
    ..Relatively little is known about the use of medication for the secondary prevention of cardiovascular disease (CVD) events in China, and the relevance to it of socioeconomic, lifestyle and health-related factors...
  22. doi request reprint Reproductive history, oral contraceptive use, and the risk of ischemic and hemorrhagic stoke in a cohort study of middle-aged Swedish women
    Ling Yang
    Clinical Trials Service Unit, Richard Doll Building, Oxford, UK
    Stroke 40:1050-8. 2009
    ..Controversy persists as to whether oral contraceptive (OC) use and reproductive history play a role in the etiology of stroke, particularly ischemic stroke. Our aim was to investigate this question in a cohort of middle-aged Swedish women...
  23. pmc The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial
    Colin Baigent
    Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford, UK
    Lancet 377:2181-92. 2011
    ..The SHARP trial aimed to assess the efficacy and safety of the combination of simvastatin plus ezetimibe in such patients...
  24. ncbi request reprint Body mass index, blood pressure, and mortality from stroke: a nationally representative prospective study of 212,000 Chinese men
    Maigeng Zhou
    Disease Surveillance Points Central Office, Chinese Center for Disease Control, Beijing, People s Republic of China
    Stroke 39:753-9. 2008
    ..Despite previous investigations, substantial uncertainty remains about the relation between body mass index (BMI) and stroke, especially in populations with a relatively low BMI but a high stroke rate...
  25. ncbi request reprint Antithrombotic therapy in patients with any form of intracranial haemorrhage: a systematic review of the available controlled studies
    Sarah L Keir
    Department of Clinical Neurosciences, Western General Hospital NHS Trust, Edinburgh, UK
    Cerebrovasc Dis 14:197-206. 2002
    ..Antithrombotic agents should be avoided where possible in patients with acute intracerebral haemorrhage...
  26. ncbi request reprint Cidea-deficient mice have lean phenotype and are resistant to obesity
    Zhihong Zhou
    Laboratories of Apoptosis Regulation, Institute of Molecular and Cell Biology, 30 Medical Dr, Singapore 117609, Singapore
    Nat Genet 35:49-56. 2003
    ..Our data thus indicate a role for Cidea in regulating energy balance and adiposity...
  27. pmc Global burden of cardiovascular disease
    John E Sanderson
    Heart 93:1175. 2007
  28. pmc Poverty and chronic diseases in Asia: challenges and opportunities
    Prabhat Jha
    Centre for Global Health Research, St Michael s Hospital, University of Toronto, Toronto, Ont
    CMAJ 177:1059-62. 2007