U Cheema

Summary

Affiliation: University College London
Country: UK

Publications

  1. pmc Evolution of oxygen utilization in multicellular organisms and implications for cell signalling in tissue engineering
    Katerina Stamati
    Stanmore Campus, UCL, London, UK
    J Tissue Eng 2:2041731411432365. 2011
  2. pmc A novel tissue engineered three-dimensional in vitro colorectal cancer model
    Agata Nyga
    Centre for Nanotechnology and Regenerative Medicine, University College London, London, UK
    Acta Biomater 9:7917-26. 2013
  3. ncbi request reprint Spatially defined oxygen gradients and vascular endothelial growth factor expression in an engineered 3D cell model
    U Cheema
    Tissue Repair and Engineering Centre, Institute of Orthopaedics and Musculoskeletal Sciences, University College London, Stanmore Campus, London, HA7 4LP, UK
    Cell Mol Life Sci 65:177-86. 2008
  4. doi request reprint Oxygen diffusion through collagen scaffolds at defined densities: implications for cell survival in tissue models
    Umber Cheema
    Tissue Repair and Engineering Centre, Institute of Orthopaedics and Musculoskeletal Sciences, UCL Division of Surgery and Interventional Science, University College London, UK
    J Tissue Eng Regen Med 6:77-84. 2012
  5. doi request reprint First implantable device for hypoxia-mediated angiogenic induction
    E Hadjipanayi
    UCL, Tissue Repair and Engineering Centre, Institute of Orthopaedics, Stanmore Campus, London, HA7 4LP, UK
    J Control Release 153:217-24. 2011
  6. ncbi request reprint Controlling physiological angiogenesis by hypoxia-induced signaling
    E Hadjipanayi
    UCL Division of Surgery and Interventional Sciences, Tissue Repair and Engineering Centre, Brockley Hill, Stanmore Campus, London HA74LP, UK
    J Control Release 146:309-17. 2010
  7. ncbi request reprint Switching off angiogenic signalling: creating channelled constructs for adequate oxygen delivery in tissue engineered constructs
    U Cheema
    Tissue Repair and Engineering Centre, Institute of Orthopaedics and Musculoskeletal Sciences, UCL Division of Surgery and Interventional Science, University College London, London, UK
    Eur Cell Mater 20:274-80; discussion 280-1. 2010
  8. ncbi request reprint 3-D in vitro model of early skeletal muscle development
    U Cheema
    Tissue Repair and Engineering Centre, University College London, RFUCMS, Institute of Orthopaedics, RNOH, Stanmore, Middlesex, United Kingdom
    Cell Motil Cytoskeleton 54:226-36. 2003
  9. doi request reprint Oxygen consumption rate of cells in 3D culture: the use of experiment and simulation to measure kinetic parameters and optimise culture conditions
    Ian Streeter
    Insitute of Orthopaedics and Musculoskeletal Science, University College London, Brockley Hill, Stanmore, United Kingdom HA7 4LP
    Analyst 136:4013-9. 2011

Collaborators

  • R A Brown
  • W Liu
  • Zimei Rong
  • E Hadjipanayi
  • Agata Nyga
  • Ian Streeter
  • Katerina Stamati
  • V Mudera
  • D Deng
  • Mark Emberton
  • Marilena Loizidou
  • Vivek Mudera

Detail Information

Publications9

  1. pmc Evolution of oxygen utilization in multicellular organisms and implications for cell signalling in tissue engineering
    Katerina Stamati
    Stanmore Campus, UCL, London, UK
    J Tissue Eng 2:2041731411432365. 2011
    ....
  2. pmc A novel tissue engineered three-dimensional in vitro colorectal cancer model
    Agata Nyga
    Centre for Nanotechnology and Regenerative Medicine, University College London, London, UK
    Acta Biomater 9:7917-26. 2013
    ..This characterization is fundamental in establishing a reproducible, complex model that could be used to advance our understanding of cancer pathology and will facilitate therapeutic drug testing. ..
  3. ncbi request reprint Spatially defined oxygen gradients and vascular endothelial growth factor expression in an engineered 3D cell model
    U Cheema
    Tissue Repair and Engineering Centre, Institute of Orthopaedics and Musculoskeletal Sciences, University College London, Stanmore Campus, London, HA7 4LP, UK
    Cell Mol Life Sci 65:177-86. 2008
    ..A VEGF response was elicited by cells exposed to low oxygen levels (20 mmHg), primarily within the construct core...
  4. doi request reprint Oxygen diffusion through collagen scaffolds at defined densities: implications for cell survival in tissue models
    Umber Cheema
    Tissue Repair and Engineering Centre, Institute of Orthopaedics and Musculoskeletal Sciences, UCL Division of Surgery and Interventional Science, University College London, UK
    J Tissue Eng Regen Med 6:77-84. 2012
    ..The high diffusion coefficients of these collagen scaffolds, as well as their material properties, render them viable tissue-engineering matrices for tissue replacement...
  5. doi request reprint First implantable device for hypoxia-mediated angiogenic induction
    E Hadjipanayi
    UCL, Tissue Repair and Engineering Centre, Institute of Orthopaedics, Stanmore Campus, London, HA7 4LP, UK
    J Control Release 153:217-24. 2011
    ....
  6. ncbi request reprint Controlling physiological angiogenesis by hypoxia-induced signaling
    E Hadjipanayi
    UCL Division of Surgery and Interventional Sciences, Tissue Repair and Engineering Centre, Brockley Hill, Stanmore Campus, London HA74LP, UK
    J Control Release 146:309-17. 2010
    ..These findings establish the angiogenic potential of HIS cells applicable to in vitro tissue modeling, implant vascularization and engineering predictable angiogenic therapies...
  7. ncbi request reprint Switching off angiogenic signalling: creating channelled constructs for adequate oxygen delivery in tissue engineered constructs
    U Cheema
    Tissue Repair and Engineering Centre, Institute of Orthopaedics and Musculoskeletal Sciences, UCL Division of Surgery and Interventional Science, University College London, London, UK
    Eur Cell Mater 20:274-80; discussion 280-1. 2010
    ..Simple static micro-channelling gives adequate perfusion and can be used to control cell generated hypoxia-induced signalling...
  8. ncbi request reprint 3-D in vitro model of early skeletal muscle development
    U Cheema
    Tissue Repair and Engineering Centre, University College London, RFUCMS, Institute of Orthopaedics, RNOH, Stanmore, Middlesex, United Kingdom
    Cell Motil Cytoskeleton 54:226-36. 2003
    ..MGF gene expression was increased 77-fold on day 3, compared to a 36-fold increase with IGF-1 on day 3. This indicates an important role for MGF in either differentiation or, more likely, a response to mechanical or tensional cues...
  9. doi request reprint Oxygen consumption rate of cells in 3D culture: the use of experiment and simulation to measure kinetic parameters and optimise culture conditions
    Ian Streeter
    Insitute of Orthopaedics and Musculoskeletal Science, University College London, Brockley Hill, Stanmore, United Kingdom HA7 4LP
    Analyst 136:4013-9. 2011
    ..These values will dictate 3D culture parameters, including maximum cell-seeding density and maximum size of the constructs, for long-term viability of tissue models...