Varodom Charoensawan

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. pmc Lineage-specific expansion of DNA-binding transcription factor families
    Varodom Charoensawan
    MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK
    Trends Genet 26:388-93. 2010
  2. pmc Genomic repertoires of DNA-binding transcription factors across the tree of life
    Varodom Charoensawan
    MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK
    Nucleic Acids Res 38:7364-77. 2010
  3. pmc The impact of gene expression regulation on evolution of extracellular signaling pathways
    Varodom Charoensawan
    Medical Research Council Laboratory of Molecular Biology, Cambridge CB20QH, United Kingdom
    Mol Cell Proteomics 9:2666-77. 2010
  4. pmc DNA sequence preferences of transcriptional activators correlate more strongly than repressors with nucleosomes
    Varodom Charoensawan
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK
    Mol Cell 47:183-92. 2012
  5. pmc DBD--taxonomically broad transcription factor predictions: new content and functionality
    Derek Wilson
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 0QH, UK
    Nucleic Acids Res 36:D88-92. 2008
  6. doi request reprint RNA sequencing reveals two major classes of gene expression levels in metazoan cells
    Daniel Hebenstreit
    Structural Studies Division, MRC Laboratory of Molecular Biology, Cambridge, UK
    Mol Syst Biol 7:497. 2011

Detail Information

Publications6

  1. pmc Lineage-specific expansion of DNA-binding transcription factor families
    Varodom Charoensawan
    MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK
    Trends Genet 26:388-93. 2010
    ..We found only three out of 131 (2%) DBD families shared by the three superkingdoms...
  2. pmc Genomic repertoires of DNA-binding transcription factors across the tree of life
    Varodom Charoensawan
    MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK
    Nucleic Acids Res 38:7364-77. 2010
    ..As pointed out before, prokaryotic TFs increase faster than linearly. We further observe a similar relationship in eukaryotic genomes with a slower increase in TFs...
  3. pmc The impact of gene expression regulation on evolution of extracellular signaling pathways
    Varodom Charoensawan
    Medical Research Council Laboratory of Molecular Biology, Cambridge CB20QH, United Kingdom
    Mol Cell Proteomics 9:2666-77. 2010
    ..This allows homologous extracellular receptors to attain specialized functions and become specific to tissues and/or developmental stages...
  4. pmc DNA sequence preferences of transcriptional activators correlate more strongly than repressors with nucleosomes
    Varodom Charoensawan
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK
    Mol Cell 47:183-92. 2012
    ..Consistent with this, we show that activators induce more nucleosome disruption upon transcriptional activation than repressors...
  5. pmc DBD--taxonomically broad transcription factor predictions: new content and functionality
    Derek Wilson
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 0QH, UK
    Nucleic Acids Res 36:D88-92. 2008
    ..Eukaryotes follow a slower rate of increase in TFs than prokaryotes, which could be due to the presence of splice variants or an increase in combinatorial control...
  6. doi request reprint RNA sequencing reveals two major classes of gene expression levels in metazoan cells
    Daniel Hebenstreit
    Structural Studies Division, MRC Laboratory of Molecular Biology, Cambridge, UK
    Mol Syst Biol 7:497. 2011
    ..These observations are confirmed in many other microarray and RNA-seq data sets of metazoan cell types...