V Chapman

Summary

Affiliation: University College London
Country: UK

Publications

  1. pmc Electrophysiological characterization of spinal neuronal response properties in anaesthetized rats after ligation of spinal nerves L5-L6
    V Chapman
    Department of Pharmacology, University College London, Gower Street, London WC1E 6BT, UK
    J Physiol 507:881-94. 1998
  2. ncbi request reprint Effects of systemic carbamazepine and gabapentin on spinal neuronal responses in spinal nerve ligated rats
    V Chapman
    Department of Pharmacology, University College London, UK
    Pain 75:261-72. 1998
  3. ncbi request reprint A novel spinal action of mexiletine in spinal somatosensory transmission of nerve injured rats
    V Chapman
    Department of Pharmacology, University College London, UK
    Pain 77:289-96. 1998
  4. ncbi request reprint The effectiveness of spinal and systemic morphine on rat dorsal horn neuronal responses in the spinal nerve ligation model of neuropathic pain
    R Suzuki
    Department of Pharmacology, University College London, UK
    Pain 80:215-28. 1999
  5. ncbi request reprint Neuronal inhibitory effects of methadone are predominantly opioid receptor mediated in the rat spinal cord in vivo
    K J Carpenter
    Department of Pharmacology, University College, Gower Street, London, WC1E 6BT, UK
    Eur J Pain 4:19-26. 2000

Detail Information

Publications5

  1. pmc Electrophysiological characterization of spinal neuronal response properties in anaesthetized rats after ligation of spinal nerves L5-L6
    V Chapman
    Department of Pharmacology, University College London, Gower Street, London WC1E 6BT, UK
    J Physiol 507:881-94. 1998
    ..We suggest that an interplay between pathological peripheral and central mechanisms may account for some of the changes that could contribute to allodynia and hyperalgesia...
  2. ncbi request reprint Effects of systemic carbamazepine and gabapentin on spinal neuronal responses in spinal nerve ligated rats
    V Chapman
    Department of Pharmacology, University College London, UK
    Pain 75:261-72. 1998
    ..Further studies at the spinal level may shed light on the physiology and pharmacology of the aberrant processes associated with neuropathic pain...
  3. ncbi request reprint A novel spinal action of mexiletine in spinal somatosensory transmission of nerve injured rats
    V Chapman
    Department of Pharmacology, University College London, UK
    Pain 77:289-96. 1998
    ..This central action may underlie some of the clinical efficacy of mexiletine in the treatment of neuropathic pain states...
  4. ncbi request reprint The effectiveness of spinal and systemic morphine on rat dorsal horn neuronal responses in the spinal nerve ligation model of neuropathic pain
    R Suzuki
    Department of Pharmacology, University College London, UK
    Pain 80:215-28. 1999
    ..Spinal opioids may be a useful approach to pain control in neuropathic pain states where systemic routes produce inadequate analgesia...
  5. ncbi request reprint Neuronal inhibitory effects of methadone are predominantly opioid receptor mediated in the rat spinal cord in vivo
    K J Carpenter
    Department of Pharmacology, University College, Gower Street, London, WC1E 6BT, UK
    Eur J Pain 4:19-26. 2000
    ..However, the ability of naloxone to reverse the effects of d -methadone may also reflect a degree of synergy between weak NMDA antagonist and opioid agonist activity...