Research Topics
| A E CavannaSummaryAffiliation: University College London Country: UK Publications
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Detail Information
Publications
Catatonic signs in Gilles de la Tourette syndromeAndrea E Cavanna
Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London WC1N3BG, UK
Cogn Behav Neurol 21:34-7. 2008..Originally described in association with schizophrenia, catatonic signs have been reported in a wide range of neuropsychiatric conditions...
The disaster was my fault!Mary M Robertson
Department of Mental Health Sciences, Royal Free and University College Medical School, University College London, London, UK
Neurocase 13:446-51. 2007..Prognostic and treatment implications are also presented, along with a review of the literature on the clinical and psychosocial impact of terrorist attacks and natural disasters on children suffering from neuropsychiatric disorders...
The behavioral spectrum of Gilles de la Tourette syndromeAndrea Eugenio Cavanna
Sobell Department of Movement Disorders, Institute of Neurology, London, UK
J Neuropsychiatry Clin Neurosci 21:13-23. 2009..The issue of whether Tourette's syndrome should still be considered as a unitary nosological entity is also addressed...
Brain mechanisms of altered conscious states during epileptic seizuresAndrea Eugenio Cavanna
Department of Neuropsychiatry, University of Birmingham, and Birmingham and Solihull Mental Health NHS Foundation Trust, Birmingham, UK
Nat Rev Neurol 5:267-76. 2009..This paper reviews novel insights into the brain mechanisms that underlie alterations of consciousness during epileptic seizures and the implications for clinical practice in terms of diagnosis and management...
Epileptic seizures and spirit possession in Haitian culture: report of four cases and review of the literatureA E Cavanna
Institute of Neurology, University College London, London, UK
Epilepsy Behav 19:89-91. 2010....
Disease-specific quality of life in young patients with tourette syndromeAndrea E Cavanna
Department of Neuropsychiatry, BSMHFT, and University of Birmingham, Birmingham, United Kingdom
Pediatr Neurol 48:111-4. 2013..In addition to focusing on core tic symptoms, the GTS-QOL-C&A showed sensitivity to the impact of behavioral comorbidities on health-related quality of life and can usefully complement existing nonspecific instruments...
Tolerability profile of clonidine in the treatment of adults with Tourette syndromeAndrea Eugenio Cavanna
The Michael Trimble Neuropsychiatry Research Group, BSMHFT and University of Birmingham, UK
Clin Neuropharmacol 35:269-72. 2012..Although clonidine is thought to have a low rate of adverse effects (AEs), little is known about its tolerability profile in adult patients with TS...
Predictors during childhood of future health-related quality of life in adults with Gilles de la Tourette syndromeAndrea E Cavanna
Department of Neuropsychiatry, University of Birmingham and BSMHFT, Birmingham, United Kingdom
Eur J Paediatr Neurol 16:605-12. 2012..The diagnosis of GTS is usually established in childhood but little is known about factors that predict the long-term well-being of patients, especially in the presence of co-morbid behavioural problems...
Tolerability profile of aripiprazole in patients with Tourette syndromeAndrea E Cavanna
Michael Trimble Neuropsychiatry Research Group, BSMHFT and University of Birmingham, Birmingham, UK
J Psychopharmacol 26:891-5. 2012..The discontinuation rate of 20.7% suggests that aripiprazole is safe and reasonably well tolerated for use in TS. The prevalence of adverse effects appears to increase with treatment duration...
Tourette syndromeAndrea E Cavanna
Department of Neuropsychiatry, University of Birmingham, Birmingham, UK
Adv Exp Med Biol 724:375-83. 2012..In conclusion, it appears that TS probably should no longer be considered merely a motor disorder and, most importantly, that TS is no longer a unitary condition, as it was previously thought...
Depression in women with epilepsy: clinical and neurobiological aspectsAndrea Eugenio Cavanna
Department of Neuropsychiatry, Queen Elizabeth Psychiatric Hospital, Birmingham, United Kingdom
Funct Neurol 24:83-7. 2009..This paper reviews the current knowledge on the neurobiological basis of depression in women with epilepsy. The emerging picture informs therapeutic strategies to improve the clinical management of this common comorbidity...
Cognitive functioning in Tourette syndromeAndrea Eugenio Cavanna
Department of Neuropsychiatry, University of Birmingham and Birmingham and Solihull Mental Health NHS Foundation Trust, United Kingdom
Discov Med 8:191-5. 2009..These cognitive difficulties are likely to reflect dysfunction with frontostriatal pathways involving the anterior cingulate circuit...
Corpus callosum abnormalities in Tourette syndrome: an MRI-DTI study of monozygotic twinsAndrea E Cavanna
Department of Neurology, Amedeo Avogadro University, Novara, Italy
J Neurol Neurosurg Psychiatry 81:533-5. 2010....
The "imprisoned illness:" motor tic disorder in Rainer Maria Rilke's Notebooks of Malte Laurids BriggeAndrea Eugenio Cavanna
Department of Neuropsychiatry, University of Birmingham and BSMHFT, Birmingham, United Kingdom
Mov Disord 25:1980-2. 2010..In this article, we report his description of a Parisian character displaying multiple motor tic symptoms, along with a brief commentary...
Pathological laughter in Gilles de la Tourette syndrome: an unusual phonic ticAndrea E Cavanna
Department of Neuropsychiatry, University of Birmingham and BSMHFT, Birmingham, UK
Mov Disord 25:2233-9. 2010..We suggest that the pathophysiological mechanisms underlying the expression of PL as a tic could involve a dissociation between frontostriatal and limbic networks...
An approach to deep brain stimulation for severe treatment-refractory Tourette syndrome: the UK perspectiveAndrea E Cavanna
Department of Neuropsychiatry, University of Birmingham and BSMHFT, Birmingham, UK
Br J Neurosurg 25:38-44. 2011..The present article illustrates the UK perspective on DBS in TS and proposes consensus-based recommendations for double-blind controlled trials...
Dissecting the Gilles de la Tourette spectrum: a factor analytic study on 639 patientsAndrea E Cavanna
Department of Neuropsychiatry, Birmingham and Solihull Mental Health NHS Foundation Trust, University of Birmingham, Barberry Building, 25 Vincent Drive, Edgbaston, Birmingham B15 2FG, UK
J Neurol Neurosurg Psychiatry 82:1320-3. 2011....
Consciousness: a neurological perspectiveAndrea E Cavanna
Department of Neuropsychiatry, University of Birmingham and BSMHFT, Birmingham, United Kingdom
Behav Neurol 24:107-16. 2011....
Clinical correlates of pathological gambling symptoms in patients with epilepsyAndrea E Cavanna
Department of Neurology, Amedeo Avogadro University, Novara, Italy
Epilepsia 49:1460-4. 2008..Alterations in the mesolimbic reward system could represent the putative neuropathological substrate for this multifaceted clinical picture...
Schizotypal personality traits in Gilles de la Tourette syndromeA E Cavanna
Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, London, UK
Acta Neurol Scand 116:385-91. 2007..The aim of this study was to quantify the prevalence of schizotypal traits in GTS and to detail the relationship between schizotypy and comorbid psychopathology...
The Gilles de la Tourette syndrome-quality of life scale (GTS-QOL): development and validationA E Cavanna
Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WC1N3BG, UK
Neurology 71:1410-6. 2008..However, no patient-reported HR-QOL measures have been developed for this population...
The precuneus and consciousnessAndrea E Cavanna
Institute of Neurology, Queen Square, London, United Kingdom
CNS Spectr 12:545-52. 2007..Specifically, its activity seems to correlate with self-reflection processes, possibly involving mental imagery and episodic/autobiographical memory retrieval...
Measuring the level and content of consciousness during epileptic seizures: the Ictal Consciousness InventoryA E Cavanna
Department of Neurology, Amedeo Avogadro University, Novara, Italy
Epilepsy Behav 13:184-8. 2008..The ICI is proposed as a user-friendly and clinically sound instrument for the measurement of ictal alterations of consciousness in patients with epilepsy...
What makes a simple partial seizure complex?Andrea E Cavanna
The Michael Trimble Neuropsychiatry Research Group, Department of Neuropsychiatry, University of Birmingham and BSMHFT, Birmingham, UK
Epilepsy Behav 22:651-8. 2011..These data, along with the localization information they provide, should be taken into account in the formulation of new criteria for the classification of seizures with focal onset...
Quality of life in young people with Tourette syndrome: a controlled studyC M Eddy
Department of Neuropsychiatry, The Barberry National Centre for Mental Health, Birmingham and Solihull Mental Health NHS Foundation Trust, Barberry Building, Birmingham, B152FG, UK
J Neurol 258:291-301. 2011..Although social aspects of QoL may be more vulnerable to TS in general, co-morbid conditions make an important contribution in determining which aspects of QoL are most affected in the individual...
Health-related quality of life measures and psychiatric comorbidity in patients with migraineM Mula
Department of Neurology, Amedeo Avogadro University, Novara, Italy
Eur J Neurol 16:1017-21. 2009..This study aimed at investigating associations between HRQoL and comorbid mood and anxiety disorders...
Quality of life in young people with treatment-responsive epilepsy: A controlled studyC M Eddy
Department of Neuropsychiatry, Birmingham and Solihull Mental Health NHS Foundation Trust, Birmingham, UK
Epilepsy Behav 19:623-6. 2010..This study investigated the effects of epilepsy on QoL in persons with treatment-responsive seizures, beyond factors directly related to the presence of seizures...
Air swallowing as a ticRimona S Weil
Institute of Neurology, Queen Square, London, UK
J Psychosom Res 65:497-500. 2008..The authors present a patient with Gilles de la Tourette syndrome who developed abdominal distension and bloating due to air swallowing. We suggest that this air swallowing may have been due to a tic...
The neural correlates of altered consciousness during epileptic seizuresAndrea E Cavanna
Department of Neuropsychiatry, University of Birmingham and Birmingham and Solihull Mental Health NHS Foundation Trust, Birmingham B15 2FG, United Kingdom
Discov Med 8:31-6. 2009..The differences in ictal semiology between patients with epilepsy offer unique avenues for understanding the relationship between pathological brain function and altered conscious states...
Phenomenology of obsessive compulsive disorder in patients with temporal lobe epilepsy or tourette syndromeMarco Mula
The Neuropsychiatry Research Group, Department of Clinical and Experimental Medicine, Section of Neurology, Amedeo Avogadro University, C so Mazzini, 18, Novara 28100, Italy
J Neuropsychiatry Clin Neurosci 20:223-6. 2008..Content of obsessive-compulsive themes focuses on sexuality and impulsiveness in Tourette syndrome and existential thoughts in temporal lobe epilepsy...
Altered Attribution of Intention in Tourette's SyndromeClare M Eddy
The Barberry, 25 Vincent Drive, Edgbaston, Birmingham, B15 2FG, United Kingdom
J Neuropsychiatry Clin Neurosci 22:348-51. 2010..Here the authors report evidence for theory of minddifficulties: patients exhibit deficits in recognizing faux pas and understanding intentionality...
Neuropsychological aspects of Tourette syndrome: a reviewClare M Eddy
Department of Psychology, University of Birmingham, Birmingham, UK
J Psychosom Res 67:503-13. 2009..These impairments may reflect dysfunction of the anterior cingulate network within the frontostriatal pathway...
The Gilles de la Tourette syndrome: a principal component factor analytic study of a large pedigreeMary M Robertson
Department of Mental Health Sciences, University College London, UK
Psychiatr Genet 17:143-52. 2007..Factor analytic studies suggest that there are more than one Gilles de la Tourette syndrome phenotype and it is not a unitary condition...
The precuneus: a review of its functional anatomy and behavioural correlatesAndrea E Cavanna
Institute of Neurology, Queen Square, London WC1N3BG, UK
Brain 129:564-83. 2006....
Consciousness, epilepsy, and emotional qualiaFrancesco Monaco
Department of Neurology, Amedeo Avogadro University, Novara, Italy
Epilepsy Behav 7:150-60. 2005..Epilepsy is confirmed to represent a privileged window over basic neurobiological mechanisms of consciousness...
Hassler and Dieckmann's seminal paper on stereotactic thalamotomy for Gilles de la Tourette syndrome: translation and critical reappraisalHugh Rickards
Department of Neuropsychiatry, Queen Elizabeth Psychiatric Hospital, Birmingham, United Kingdom
Mov Disord 23:1966-72. 2008..We present a translation of this paper and discussion in English...
