Aedin Cassidy

..This article outlines the evidence for exercise and dietary influences on many of the major disease risks for women around the menopause and after, including cardiovascular diseases, cancer and osteoporosis...

..To date, few studies have examined associations between the wide range of flavonoid subclasses and risk of ischemic, hemorrhagic, and total stroke...

..We present here the analyses of the PA, dietary and anthropometry data...

..These data reinforce the importance of weight maintenance and increasing consumption of diets rich in plant-based foods to prevent CVD and type 2 diabetes...

..Available data suggest isoflavones are more bioavailable than other flavonoid subclasses. This review will focus on our current understanding of factors affecting isoflavone absorption and metabolism in humans...

..Most evidence relates to soy isoflavones, but there is some evidence for lignans. Further robust studies assessing the effects of whole soy foods on cardiovascular outcomes are needed...

..Future studies should focus on high-risk post-menopausal women, especially in the areas of diabetes, CVD, breast cancer and bone health...

..Only 30% of the subjects were equol producers and no differences in equol production with age or gender were observed...

..Although a high intake of some flavonoid subclasses may reduce cardiovascular disease mortality, data regarding the in vivo mechanisms of action are limited...

..Dietary flavonoids have beneficial effects on blood pressure in intervention settings, but there is limited information on habitual intake and risk of hypertension in population-based studies...

..There is substantial interest in chocolate and flavan-3-ols for the prevention of cardiovascular disease (CVD)...

..Limited evidence suggests that there may be interactions between environmental factors at a neighborhood level and the development of obesity, with the availability and accessibility of food outlets being potentially important...

..The aim of the present study was to examine the relative impact of composition, flavonoid structure and dose...

..Dietary flavonoids exert potential beneficial effects on endothelial function in short-term trials; however, the relationship between habitual intake and risk of MI in women is unknown...

..Future obesity interventions should consider the mediating role of diet quality and activity in the relationship between EF and adiposity in children...

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..To assess the effect of dietary flavonoids on cardiovascular disease (CVD) risk in postmenopausal women with type 2 diabetes on established statin and hypoglycemic therapy...

..This study aims to examine the association between PA and rainfall in 9-10 year old children, and how it may be modified by school policies...

..In conclusion, total flavonoid intake was positively associated with BMD, with effects observed for anthocyanins and flavones at both the hip and spine, supporting a role for flavonoids present in plant-based foods on bone health. ...

..The effect of diet on bone mineral density (BMD) remains controversial, mainly because of difficulties in isolating dietary factors from the confounding influences of age, lifestyle, and genetic factors...

..The approach allows the influence of individual fetal nutrition on adult insulin resistance to be distinguished from effects that are mediated by confounding factors in the maternal environment...

..Poor diet in childhood increases risk of obesity but the relationship between access to food and children's food choice is underexplored. We determined relationships between distance to and density of food outlets on children's food choice...

..The purpose of this study was to examine placental growth factor's (PlGF) predictive value in relation to coronary heart disease (CHD) risk in healthy women...

..Future efforts to establish the biological activities of anthocyanins should therefore include the investigation of phenolic acid and aldehyde products of degradation, along with their respective metabolites...

..02). In conclusion, these data suggest that chronic consumption of 500 mg/d of elderberry extract for 12 wk is apparently safe, but ineffective in altering biomarkers of CVD risk in healthy postmenopausal women...

..These data suggest that few school factors are associated with FMI, and provide limited pointers to inform potential future school-based interventions to reduce obesity...

..Leukocyte telomere length is associated with diseases of aging, but there is limited knowledge of diet and lifestyle determinants...

..The aim of this meta-analysis was to assess the effects of isoflavone-rich foods or supplements on a biomarker of breast cancer risk, women's mammographic density...

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..The beneficial effects of flavonoid consumption on cardiovascular risk are supported by mechanistic and epidemiologic evidence...

..The relatively high heritability of specific dietary components implicates taste perception as a possible target for future genetic studies...

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..The targeted model of improving access to fruit and vegetables was effective in increasing intake; however future controlled trials are required to objectively examine potential effects on fruit and vegetable intake and health outcomes...

..These findings suggest that diet quality is independently associated with children's weight status. Future work should consider if diet quality scores could be key components of interventions designed to reduce obesity in children...

..Evidence suggests that the consumption of anthocyanin-rich foods beneficially affects cardiovascular health; however, the absorption, distribution, metabolism, and elimination (ADME) of anthocyanin-rich foods are relatively unknown...

..To investigate the association between birth weight and lipid levels in a cohort of UK female twins...

..Consequently, these compounds should be the target of future bioavailability and bioactivity studies to establish the true occurrence and impact of anthocyanins on human health...

..Taken together, these data suggest that p38 is essential in sulforaphane-mediated COX-2 suppression and provide new insights into the molecular mechanisms of sulforaphane in the chemoprevention of bladder cancer...