Andrew P Carter

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. doi request reprint Crystal clear insights into how the dynein motor moves
    Andrew P Carter
    Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK
    J Cell Sci 126:705-13. 2013
  2. pmc Crystal structure of the dynein motor domain
    Andrew P Carter
    Department of Cellular and Molecular Pharmacology, Howard Hughes Medical Institute, University of California San Francisco, 600 16th Street, San Francisco, CA 94158, USA
    Science 331:1159-65. 2011
  3. pmc Force-induced bidirectional stepping of cytoplasmic dynein
    Arne Gennerich
    The Howard Hughes Medical Institute and the Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA 94158 2200, USA
    Cell 131:952-65. 2007
  4. pmc Structure and functional role of dynein's microtubule-binding domain
    Andrew P Carter
    Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA
    Science 322:1691-5. 2008
  5. pmc Communication between the AAA+ ring and microtubule-binding domain of dynein
    Andrew P Carter
    Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA
    Biochem Cell Biol 88:15-21. 2010
  6. pmc Insights into dynein motor domain function from a 3.3-Å crystal structure
    Helgo Schmidt
    Medical Research Council Laboratory of Molecular Biology, Cambridge, UK
    Nat Struct Mol Biol 19:492-7, S1. 2012
  7. pmc A structural analysis of the AAA+ domains in Saccharomyces cerevisiae cytoplasmic dynein
    Emma S Gleave
    MRC Laboratory of Molecular Biology, Francis Crick Ave, Cambridge CB2 0QH, UK
    J Struct Biol 186:367-75. 2014
  8. pmc Single-molecule analysis of dynein processivity and stepping behavior
    Samara L Reck-Peterson
    Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA
    Cell 126:335-48. 2006

Collaborators

Detail Information

Publications8

  1. doi request reprint Crystal clear insights into how the dynein motor moves
    Andrew P Carter
    Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK
    J Cell Sci 126:705-13. 2013
    ..Even the way the two motor domains in a dynein dimer walk processively along the microtubule is unusual...
  2. pmc Crystal structure of the dynein motor domain
    Andrew P Carter
    Department of Cellular and Molecular Pharmacology, Howard Hughes Medical Institute, University of California San Francisco, 600 16th Street, San Francisco, CA 94158, USA
    Science 331:1159-65. 2011
    ..The arrangement of these elements provides clues as to how adenosine triphosphate-driven conformational changes might be transmitted across the motor domain...
  3. pmc Force-induced bidirectional stepping of cytoplasmic dynein
    Arne Gennerich
    The Howard Hughes Medical Institute and the Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA 94158 2200, USA
    Cell 131:952-65. 2007
    ..These results suggest a model for how dynein's two motor domains coordinate their activities during normal processive motility and provide new clues for understanding dynein-based motility in living cells...
  4. pmc Structure and functional role of dynein's microtubule-binding domain
    Andrew P Carter
    Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA
    Science 322:1691-5. 2008
    ..Surprisingly, functional data suggest that the MTBD, and not the ATPase domain, is the main determinant of the direction of dynein motility...
  5. pmc Communication between the AAA+ ring and microtubule-binding domain of dynein
    Andrew P Carter
    Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA
    Biochem Cell Biol 88:15-21. 2010
    ..A recent crystal structure of dynein's MTBD sheds new light on how this long-range communication along a coiled coil might occur...
  6. pmc Insights into dynein motor domain function from a 3.3-Å crystal structure
    Helgo Schmidt
    Medical Research Council Laboratory of Molecular Biology, Cambridge, UK
    Nat Struct Mol Biol 19:492-7, S1. 2012
    ..Nucleotide soaking experiments show that the main ATP hydrolysis site in dynein (AAA1) is in a low-nucleotide affinity conformation and reveal the nucleotide interactions of the other three sites (AAA2, AAA3 and AAA4)...
  7. pmc A structural analysis of the AAA+ domains in Saccharomyces cerevisiae cytoplasmic dynein
    Emma S Gleave
    MRC Laboratory of Molecular Biology, Francis Crick Ave, Cambridge CB2 0QH, UK
    J Struct Biol 186:367-75. 2014
    ..We analyse how the different AAA+ domains have diverged from each other. We discuss how this is related to the function of dynein as a motor protein and how the AAA+ domains of dynein compare to those of other AAA+ proteins. ..
  8. pmc Single-molecule analysis of dynein processivity and stepping behavior
    Samara L Reck-Peterson
    Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA
    Cell 126:335-48. 2006
    ....