Neil O Carragher

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. doi request reprint Advancing cancer drug discovery towards more agile development of targeted combination therapies
    Neil O Carragher
    Edinburgh Cancer Research UK Centre, University of Edinburgh, Western General Hospital, Crewe Road South, Edinburgh, UK
    Future Med Chem 4:87-105. 2012
  2. ncbi request reprint Combining imaging and pathway profiling: an alternative approach to cancer drug discovery
    Neil O Carragher
    Edinburgh Cancer Research UK Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, UK
    Drug Discov Today 17:203-14. 2012
  3. doi request reprint Extracellular palladium-catalysed dealkylation of 5-fluoro-1-propargyl-uracil as a bioorthogonally activated prodrug approach
    Jason T Weiss
    Edinburgh Cancer Research UK Centre, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, UK
    Nat Commun 5:3277. 2014
  4. doi request reprint Real-time study of E-cadherin and membrane dynamics in living animals: implications for disease modeling and drug development
    Alan Serrels
    Edinburgh Cancer Research Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom
    Cancer Res 69:2714-9. 2009

Collaborators

Detail Information

Publications4

  1. doi request reprint Advancing cancer drug discovery towards more agile development of targeted combination therapies
    Neil O Carragher
    Edinburgh Cancer Research UK Centre, University of Edinburgh, Western General Hospital, Crewe Road South, Edinburgh, UK
    Future Med Chem 4:87-105. 2012
    ....
  2. ncbi request reprint Combining imaging and pathway profiling: an alternative approach to cancer drug discovery
    Neil O Carragher
    Edinburgh Cancer Research UK Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, UK
    Drug Discov Today 17:203-14. 2012
    ..The implementation of such approaches at early stages of the drug discovery process enables more informed decisions on candidate drug selection and how to maximise and predict efficacy before clinical development...
  3. doi request reprint Extracellular palladium-catalysed dealkylation of 5-fluoro-1-propargyl-uracil as a bioorthogonally activated prodrug approach
    Jason T Weiss
    Edinburgh Cancer Research UK Centre, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, UK
    Nat Commun 5:3277. 2014
    ..The in vitro efficacy shown by this masking/activation strategy underlines its potential to develop a bioorthogonally activated prodrug approach and supports further in vivo investigations. ..
  4. doi request reprint Real-time study of E-cadherin and membrane dynamics in living animals: implications for disease modeling and drug development
    Alan Serrels
    Edinburgh Cancer Research Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom
    Cancer Res 69:2714-9. 2009
    ..Furthermore, this work highlights critical differences in molecular dynamics in vitro and in vivo, which have important implications for the use of cultured disease models as surrogates for living tissue...