Danielle Carpenter

Summary

Affiliation: University of Nottingham
Country: UK

Publications

  1. pmc Accuracy and differential bias in copy number measurement of CCL3L1 in association studies with three auto-immune disorders
    Danielle Carpenter
    Centre for Genetics and Genomics and School of Biology, University of Nottingham, UK
    BMC Genomics 12:418. 2011
  2. doi request reprint CCL3L1 copy number, CCR5 genotype and susceptibility to tuberculosis
    Danielle Carpenter
    School of Life Sciences, University of Nottingham, Nottingham NG7 2UH, UK
    BMC Med Genet 15:5. 2014
  3. pmc Functional effects of CCL3L1 copy number
    D Carpenter
    Centre for Genetics and Genomics and School of Biology, University of Nottingham, Nottingham, UK
    Genes Immun 13:374-9. 2012
  4. pmc CCL3L1 copy number and susceptibility to malaria
    Danielle Carpenter
    Centre for Genetics and Genomics, School of Biology, University of Nottingham, Nottingham NG7 2UH, UK
    Infect Genet Evol 12:1147-54. 2012
  5. pmc The role of CACNA1S in predisposition to malignant hyperthermia
    Danielle Carpenter
    MH Investigation Unit, Academic Unit of Anaesthesia, St James s University Hospital, Leeds, LS9 7TF, UK
    BMC Med Genet 10:104. 2009
  6. doi request reprint A RYR1 mutation associated with recessive congenital myopathy and dominant malignant hyperthermia in Asian families
    Danielle Carpenter
    MH Investigation Unit, Academic Unit Anaesthesia, St James s University Hospital, Leeds LS9 7TF, UK
    Muscle Nerve 40:633-9. 2009
  7. doi request reprint Genetics of susceptibility to malaria related phenotypes
    Danielle Carpenter
    Faculty of Biological Sciences, Institute of Integrative and Comparative Biology, University of Leeds, Leeds, UK
    Infect Genet Evol 9:97-103. 2009
  8. doi request reprint Analysis of RYR1 haplotype profile in patients with malignant hyperthermia
    D Carpenter
    MH Investigation Unit, Academic Unit Anaesthesia, Leeds Institute of Molecular Medicine, St James s University Hospital, Leeds LS97TF
    Ann Hum Genet 73:10-8. 2009
  9. ncbi request reprint Immunogenetic control of antibody responsiveness in a malaria endemic area
    Danielle Carpenter
    Institute of Integrative and Comparative Biology, University of Leeds, Leeds, England
    Hum Immunol 68:165-9. 2007
  10. ncbi request reprint Unique TCR beta-subunit variable gene haplotypes in Africans
    Ian J Donaldson
    Molecular Medicine Unit, Level 6, Clinical Sciences Building, St James s University Hospital, Leeds, LS9 7TF, UK
    Immunogenetics 53:884-93. 2002

Collaborators

Detail Information

Publications11

  1. pmc Accuracy and differential bias in copy number measurement of CCL3L1 in association studies with three auto-immune disorders
    Danielle Carpenter
    Centre for Genetics and Genomics and School of Biology, University of Nottingham, UK
    BMC Genomics 12:418. 2011
    ..As the products of CCL3L1 and CCL4L1 potentially play a role in autoimmunity we performed case control association studies with Crohn's disease, rheumatoid arthritis and psoriasis clinical cohorts...
  2. doi request reprint CCL3L1 copy number, CCR5 genotype and susceptibility to tuberculosis
    Danielle Carpenter
    School of Life Sciences, University of Nottingham, Nottingham NG7 2UH, UK
    BMC Med Genet 15:5. 2014
    ..The three populations include patients with clinically diagnosed pulmonary TB, as well as other, less prevalent forms of extrapulmonary TB...
  3. pmc Functional effects of CCL3L1 copy number
    D Carpenter
    Centre for Genetics and Genomics and School of Biology, University of Nottingham, Nottingham, UK
    Genes Immun 13:374-9. 2012
    ..The data also provide evidence that expression of CCL3 predominates in both protein and mRNA, and therefore the observed variation of CCL3 is potentially more important biologically than that of CNV of CCL3L1...
  4. pmc CCL3L1 copy number and susceptibility to malaria
    Danielle Carpenter
    Centre for Genetics and Genomics, School of Biology, University of Nottingham, Nottingham NG7 2UH, UK
    Infect Genet Evol 12:1147-54. 2012
    ..We identified a high level of copy number haplotype diversity and find some evidence for an association of low CCL3L1 copy number with protection from anaemia...
  5. pmc The role of CACNA1S in predisposition to malignant hyperthermia
    Danielle Carpenter
    MH Investigation Unit, Academic Unit of Anaesthesia, St James s University Hospital, Leeds, LS9 7TF, UK
    BMC Med Genet 10:104. 2009
    ..This study focuses on the gene CACNA1S which encodes the alpha1 subunit of the DHPR, in order to establish whether CACNA1S plays a major role in MH susceptibility in the UK...
  6. doi request reprint A RYR1 mutation associated with recessive congenital myopathy and dominant malignant hyperthermia in Asian families
    Danielle Carpenter
    MH Investigation Unit, Academic Unit Anaesthesia, St James s University Hospital, Leeds LS9 7TF, UK
    Muscle Nerve 40:633-9. 2009
    ..One individual from each of these families was fully sequenced for RYR1 and presented with the non-synonymous change c.11315G>A/p.R3772Q. When present in the homozygous state c.11315*A is associated with myopathic symptoms...
  7. doi request reprint Genetics of susceptibility to malaria related phenotypes
    Danielle Carpenter
    Faculty of Biological Sciences, Institute of Integrative and Comparative Biology, University of Leeds, Leeds, UK
    Infect Genet Evol 9:97-103. 2009
    ..There was no evidence for association with polymorphisms in the IL10 promoter, IL1 gene cluster, or from the IL4/IL13 region...
  8. doi request reprint Analysis of RYR1 haplotype profile in patients with malignant hyperthermia
    D Carpenter
    MH Investigation Unit, Academic Unit Anaesthesia, Leeds Institute of Molecular Medicine, St James s University Hospital, Leeds LS97TF
    Ann Hum Genet 73:10-8. 2009
    ..G2434R/c.7300G>A. These results demonstrate the applicability of this new and practical method for population based association analysis...
  9. ncbi request reprint Immunogenetic control of antibody responsiveness in a malaria endemic area
    Danielle Carpenter
    Institute of Integrative and Comparative Biology, University of Leeds, Leeds, England
    Hum Immunol 68:165-9. 2007
    ..There was a significant association between the IL1RN alleles and total IgE. Weak evidence for association was present between polymorphisms in the IL10 promoter region and both anti-P falciparum IgE and IgG4 antibodies...
  10. ncbi request reprint Unique TCR beta-subunit variable gene haplotypes in Africans
    Ian J Donaldson
    Molecular Medicine Unit, Level 6, Clinical Sciences Building, St James s University Hospital, Leeds, LS9 7TF, UK
    Immunogenetics 53:884-93. 2002
    ..Evidence suggests that malaria is not responsible for selection of these haplotypes. Overall, this study highlights large differences in the genetic constitution of the TCRB locus between Africans and other populations...
  11. doi request reprint Accurate measurement of gene copy number for human alpha-defensin DEFA1A3
    Fayeza F Khan
    School of Biology, Queen s Medical Centre, University of Nottingham, Nottingham NG7 2UH, UK
    BMC Genomics 14:719. 2013
    ..The copy-variable alpha-defensin locus DEFA1A3 on human chromosome 8 commonly varies between 4 and 10 copies per diploid genome, and presents considerable challenges for accurate high-throughput typing...