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Genomes and GenesSpecies | Francesco P CappuccioSummaryAffiliation: University of Warwick Country: UK Publications
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Publications
A community programme to reduce salt intake and blood pressure in Ghana [ISRCTN88789643]Francesco P Cappuccio
Clinical Sciences Research Institute, Warwick Medical School, UHCW Campus, Clifford Bridge Road, Coventry CV2 2DX, UK
BMC Public Health 6:13. 2006..BP can be lowered by reducing salt intake. In Africa salt is added to the food by the consumer, as processed food is rare. A population-wide approach with programmes based on health education and promotion is thus possible...- Quantity and quality of sleep and incidence of type 2 diabetes: a systematic review and meta-analysisFrancesco P Cappuccio
University of Warwick, Warwick Medical School, Clinical Sciences Research Institute, Coventry, UK
Diabetes Care 33:414-20. 2010..To assess the relationship between habitual sleep disturbances and the incidence of type 2 diabetes and to obtain an estimate of the risk... - Sleep duration and all-cause mortality: a systematic review and meta-analysis of prospective studiesFrancesco P Cappuccio
University of Warwick, Warwick Medical School, Clinical Sciences Research Institute, Coventry, UK
Sleep 33:585-92. 2010..Increasing evidence suggests an association between both short and long duration of habitual sleep with adverse health outcomes... - Commentary: Controversies in NICE guidance on lipid modification for the prevention of cardiovascular diseaseFrancesco P Cappuccio
Clinical Sciences Research Institute, University of Warwick Medical School, Coventry CV2 2DX
BMJ 336:1248-9. 2008 
Sleep duration predicts cardiovascular outcomes: a systematic review and meta-analysis of prospective studiesFrancesco P Cappuccio
Warwick Medical School, University of Warwick, CSB Building, UHCW Campus, Clifford Bridge Road, Coventry, UK
Eur Heart J 32:1484-92. 2011..41, 1.19-1.68, P < 0.0001) with no evidence of publication bias (P = 0.92, P = 0.96, and P = 0.79, respectively). Conclusion Both short and long duration of sleep are predictors, or markers, of cardiovascular outcomes...
Self-monitoring of blood pressure in primary care: is it useful?Francesco P Cappuccio
Clinical Sciences Research Institute, Warwick Medical School, Coventry, United Kingdom
Am J Hypertens 18:1421. 2005- Implementing a 48 h EWTD-compliant rota for junior doctors in the UK does not compromise patients' safety: assessor-blind pilot comparisonF P Cappuccio
Sleep, Health and Society Programme, Clinical Sciences Research Institute, Warwick Medical School, Coventry, CV2 2DX, UK
QJM 102:271-82. 2009..Surveys of doctors' subjective opinions on shift work have not provided reliable objective data with which to evaluate its efficacy... - A population-based study of reduced sleep duration and hypertension: the strongest association may be in premenopausal womenSaverio Stranges
Health Sciences Research Institute, University of Warwick Medical School, Coventry, United Kingdom
J Hypertens 28:896-902. 2010..We therefore examined cross-sectional sex-specific associations of sleep duration with hypertension in a large population-based sample from the Western New York Health Study (1996<2001)... - Cross-sectional versus prospective associations of sleep duration with changes in relative weight and body fat distribution: the Whitehall II StudySaverio Stranges
Cardiovascular Medicine and Epidemiology Group, Clinical Sciences Research Institute, University of Warwick Medical School, Coventry, England
Am J Epidemiol 167:321-9. 2008..23, 1.12), nor with the incidence of obesity (odds ratio(adjusted) = 1.05, 95% CI: 0.60, 1.82). There is no temporal relation between short duration of sleep and future changes in measures of body weight and central adiposity... - Correlates of short and long sleep duration: a cross-cultural comparison between the United Kingdom and the United States: the Whitehall II Study and the Western New York Health StudySaverio Stranges
Cardiovascular Medicine and Epidemiology Group, Clinical Sciences Research Institute, University of Warwick Medical School, University Hospital Warwickshire and Coventry Campus, Clifford Bridge Road, Coventry, United Kingdom
Am J Epidemiol 168:1353-64. 2008..97 (95% CI: 0.95, 0.99)). Being unmarried, being overweight, and having poor general health are associated with short sleep and may contribute to observed disease associations. Long sleep may represent an epiphenomenon of comorbidity... - Ethnic and sex differences in circulating endotoxin levels: A novel marker of atherosclerotic and cardiovascular risk in a British multi-ethnic populationMichelle A Miller
Clinical Sciences Research Institute, Warwick Medical School, Coventry, UK
Atherosclerosis 203:494-502. 2009..Moreover, ethnic differences in pro-inflammatory markers may be associated with ethnic differences in atherosclerotic and cardiovascular (CVD) and coronary heart disease (CHD) risk... - Gender differences in the cross-sectional relationships between sleep duration and markers of inflammation: Whitehall II studyMichelle A Miller
The University of Warwick, Clinical Sciences Research Institute, UHCW Campus, Warwick Medical School, Coventry, UK
Sleep 32:857-64. 2009..To examine the relationships between sleep and inflammatory markers because these may be important in the development of cardiovascular disease... - Gender-specific associations of short sleep duration with prevalent and incident hypertension: the Whitehall II StudyFrancesco P Cappuccio
Clinical Sciences Research Institute, Warwick Medical School, Coventry, United Kingdom
Hypertension 50:693-700. 2007..42 [95% CI: 0.94 to 2.16]; odds ratio: 1.31 [95% CI: 0.65 to 2.63], respectively). Sleep deprivation may produce detrimental cardiovascular effects among women... - Meta-analysis of short sleep duration and obesity in children and adultsFrancesco P Cappuccio
Clinical Sciences Research Institute, University of Warwick Medical School, Coventry, UK
Sleep 31:619-26. 2008..Recent epidemiological studies suggest that short sleep duration may be associated with the development of obesity from childhood to adulthood... - Relationships between sleep duration and von Willebrand factor, factor VII, and fibrinogen: Whitehall II studyMichelle A Miller
University of Warwick, Clinical Sciences Research Institute, Warwick Medical School, UHCW Campus, Clifford Bridge Road, Coventry CV2 2DX, England
Arterioscler Thromb Vasc Biol 30:2032-8. 2010..To examine the relationship between sleep duration and hemostatic factors in a well-characterized cohort... - Telomere length attrition, a marker of biological senescence, is inversely correlated with triglycerides and cholesterol in South Asian males with type 2 diabetes mellitusAlison L Harte
Clinical Sciences Research Laboratories, Division of Metabolic and Vascular Health, Warwick Medical School, University of Warwick, University Hospital Coventry and Warwickshire, Coventry CV2 2DX, UK
Exp Diabetes Res 2012:895185. 2012..This study highlights enhanced biological ageing among South Asian, T2DM men, which appears to be tracked by changes in lipids and BMI, suggesting that raised lipids and BMI may directly contribute to premature ageing... - Diarrhoea, acute respiratory infection, and fever among children in the Democratic Republic of CongoNgianga Bakwin Kandala
University of Warwick, Warwick Medical School, Clinical Sciences Research Institute, Clifford Bridge Road, Coventry, CV2 2DX, UK
Soc Sci Med 68:1728-36. 2009..Understanding these complex relationships through disease prevalence maps can facilitate design of targeted intervention programs for reconstruction and achievement of the MDGs... - Higher selenium status is associated with adverse blood lipid profile in British adultsSaverio Stranges
Health Sciences Research Institute, University of Warwick Medical School, Coventry CV47AL, UK
J Nutr 140:81-7. 2010..Randomized and mechanistic evidence is necessary to assess causality and to evaluate the impact of this association on cardiovascular risk... - Ethnic variation in levels of circulating IgG autoantibodies to oxidised low-density lipoproteinMichelle A Miller
Warwick University, Clinical Sciences Research Institute, Clinical Sciences Building, UHCW Campus, Warwick Medical School, Clifford Bridge Road, Coventry, CV2 2DX, United Kingdom
Atherosclerosis 203:126-36. 2009..Oxidised low-density lipoprotein (Ox-LDL) plays a key role in atherosclerosis. Our aim was to determine whether serum autoantibodies against Ox-LDL (Ab Ox-LDL) differ by ethnic group... - Associations of selenium status with cardiometabolic risk factors: an 8-year follow-up analysis of the Olivetti Heart studySaverio Stranges
Health Sciences Research Institute, University of Warwick Medical School, Coventry, UK
Atherosclerosis 217:274-8. 2011..We therefore examined cross-sectional and prospective relationships of serum selenium concentrations with cardiometabolic risk factors including blood pressure, diabetes and blood lipids in the Olivetti Heart Study... - Inflammation, sleep, obesity and cardiovascular diseaseMichelle A Miller
Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, Coventry, CV2 2DX, UK
Curr Vasc Pharmacol 5:93-102. 2007..AIM: To review current evidence regarding the endocrine, metabolic, cardiovascular and immune functions and their interactions with regard to sleep, given the current evidence that sleep disturbances may affect each of these areas... - Body size and blood pressure: an analysis of Africans and the African diasporaFrancesco P Cappuccio
Clinical Sciences Research Institute, Warwick Medical School, Coventry, UK
Epidemiology 19:38-46. 2008..Blood pressure is directly and causally associated with body mass index (BMI) in populations worldwide. However, the relationship may vary across BMI in populations of African origin... - Effects of long-term selenium supplementation on the incidence of type 2 diabetes: a randomized trialSaverio Stranges
State University of New York at Buffalo and Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, New York, USA
Ann Intern Med 147:217-23. 2007..Findings from animal models suggest that selenium supplementation improves glucose metabolism... - Spatial analysis of risk factors for childhood morbidity in NigeriaNgianga Bakwin Kandala
Clinical Sciences Research Institute, Warwick Medical School, Coventry, United Kingdom
Am J Trop Med Hyg 77:770-9. 2007..Our maps are a novel and relevant tool to help local governments to improve health-care interventions and achieve Millennium Development Goals (MDG4)... - Sleep in children and adolescents: a worrying scenario: can we understand the sleep deprivation-obesity epidemic?Andrew Currie
Clinical Sciences Research Institute, Warwick Medical School, Coventry, UK
Nutr Metab Cardiovasc Dis 17:230-2. 2007 - Malnutrition among children under the age of five in the Democratic Republic of Congo (DRC): does geographic location matter?Ngianga Bakwin Kandala
University of Warwick, Warwick Medical School, Health Sciences Research Institute, Warwick Evidence, Gibbet Hill, CV4 7AL, Coventry, UK
BMC Public Health 11:261. 2011..We investigate the impact of geographic location on child nutritional status by mapping the residual net effect of malnutrition while accounting for important risk factors... - Children under pressure: an underestimated burden?Saverio Stranges
Clinical Sciences Research Institute, Warwick Medical School, Coventry, UK
Arch Dis Child 92:288-90. 2007 - HindIII(+/-) polymorphism of the Y chromosome, blood pressure, and serum lipids: no evidence of association in three white populationsPaola Russo
Unit of Epidemiology and Population Genetics, Institute of Food Sciences, CNR, Avellino, Italy
Am J Hypertens 19:331-8. 2006.... - Association between the Thr715Pro P-selectin gene polymorphism and soluble P-selectin levels in a multiethnic population in South LondonMichelle A Miller
Department of Community Health Sciences, St George s Hospital Medical School, London, UK
Thromb Haemost 92:1060-5. 2004..Lower levels of sP-selectin were not accounted for by this polymorphism in blacks, in whom the C allele was very rare... - A prospective study of change in sleep duration: associations with mortality in the Whitehall II cohortJane E Ferrie
Internationale Centre for Health and Society, Department of Epidemiology and Public Health, University College London Medical School, London, UK
Sleep 30:1659-66. 2007..We investigated associations of sleep duration and change in sleep duration with all-cause, cardiovascular, and non-cardiovascular mortality... - Diagnostic criteria for metabolic syndrome: a comparative analysis in an unselected sample of adult male populationPasquale Strazzullo
Department of Clinical and Experimental Medicine, Federico II University of Naples, 80131 Naples, Italy
Metabolism 57:355-61. 2008.... - Aldosterone synthase gene (CYP11B2) C-344T polymorphism, plasma aldosterone, renin activity and blood pressure in a multi-ethnic populationAntonio Barbato
Department of Community Health Sciences, St George s Hospital Medical School, London, UK
J Hypertens 22:1895-901. 2004..The aldosterone synthase gene (CYP1B2) locus is a candidate region involved in the development of hypertension... - Blood pressure control by home monitoring: meta-analysis of randomised trialsFrancesco P Cappuccio
Department of Community Health Sciences, St George s Hospital Medical School, London SW17 0RE
BMJ 329:145. 2004..To determine the effect of home blood pressure monitoring on blood pressure levels and proportion of people with essential hypertension achieving targets... - Prevalence, detection, management, and control of hypertension in Ashanti, West AfricaFrancesco P Cappuccio
Department of Community Health Sciences, St George s Hospital Medical School, Cranmer Terrace, London SW17 0RE, UK
Hypertension 43:1017-22. 2004..Detection rates are suboptimal in both men and women, especially in rural areas. Adequate treatment of high BP is at a very low level. There is an urgent need for preventive strategies on hypertension control in Ghana... - Ethnic differences in circulating soluble adhesion molecules: the Wandsworth Heart and Stroke StudyMichelle A Miller
Department of General Practice and Primary Care, St George s Hospital Medical School, Cranmer Terrace, London SW17 ORE, U K
Clin Sci (Lond) 104:591-8. 2003..These relationships may contribute to the low risk of coronary heart disease seen in people of African origin living in England... - Application of Framingham risk estimates to ethnic minorities in United Kingdom and implications for primary prevention of heart disease in general practice: cross sectional population based studyFrancesco P Cappuccio
Department of General Practice and Primary Care, St George s Hospital Medical School, London SW17 0RE, UK
BMJ 325:1271. 2002..To compare the 10 year risk of coronary heart disease (CHD), stroke, and combined cardiovascular disease (CVD) estimated from the Framingham equations... - The relationship of waist circumference to blood pressure: the Olivetti Heart StudyAlfonso Siani
Institute of Food Science and Technology, National Research Council, Avellino, Italy
Am J Hypertens 15:780-6. 2002..The aim of this study was to investigate the role of central adiposity in the association between overweight, high BP, and insulin resistance... - Interaction between the C(-344)T polymorphism of CYP11B2 and age in the regulation of blood pressure and plasma aldosterone levels: cross-sectional and longitudinal findings of the Olivetti Prospective Heart StudyPaola Russo
Epidemiology and Prevention, Institute of Food Science and Technology, National Research Council of Italy, Avellino, Italy
J Hypertens 20:1785-92. 2002..To study the interaction between the C(-344)T polymorphism and known determinants (age, body mass and dietary sodium) of blood pressure and plasma aldosterone... - Homocysteine levels in men and women of different ethnic and cultural background living in EnglandFrancesco P Cappuccio
Department of General Practice and Primary Care, St George s Hospital Medical School, Cranmer Terrace, SW17 0RE, London, UK
Atherosclerosis 164:95-102. 2002..They are in part accounted for by their vegetarianism. These differences in tHcy are large enough to be important contributors to the risk of vascular disease and may be preventable by simple targeted population strategies... - Rural and semi-urban differences in salt intake, and its dietary sources, in Ashanti, West AfricaSally M Kerry
Department of Community Health Sciences, St. George's Hospital Medical School, Cranmer Terrace, London
Ethn Dis 15:33-9. 2005..While no significant differences were in the amount of salt consumed, the sources of salt differed between rural and semi-urban settings. Finally, rural villagers ate more potassium than semi-urban participants... - Reducing selection bias in a cluster randomized trial in West African villagesSally M Kerry
Department of Community Health Sciences, St George's Hospital Medical School, London, UK
Clin Trials 2:125-9. 2005.... - Calcium urolithiasis, blood pressure and salt intakeFrancesca Timio
Department of Community Health Sciences, St George's Hospital Medical School, London, UK
Blood Press 12:122-7. 2003..However, the "relative" hypercalciuria seen in stone-formers is independent of salt intake and may well reflect an underlying genetic predisposition... - Race-specific differences in antioxidant enzyme activity in patients with type 2 diabetes: a potential association with the risk of developing nephropathyKarima Zitouni
Department of Cellular and Molecular Medicine, St. George's Hospital NHS Trust, Thomas Addison Diabetes Centre, London SW17 ORE, UK
Diabetes Care 28:1698-703. 2005..CONCLUSIONS: SOD and GPx enzyme activities vary according to race and could account for differences in lipid hydroperoxide. In patients of African origin, susceptibility to renal disease may be associated with lowered GPx activity... - Circulating soluble E-selectin levels and the Ser 128Arg polymorphism in individuals from different ethnic groupsMichelle A Miller
Department of Community Health Sciences, St George s Hospital Medical School, Cranmer Terrace, London SW17 ORE, UK
Nutr Metab Cardiovasc Dis 15:65-70. 2005..The aim of this study was to investigate whether the Ser128 Arg polymorphism of the E-selectin gene is associated with soluble E-selectin levels in individuals from a multiethnic population... - Blood pressure and body mass index in lean rural and semi-urban subjects in West AfricaSally M Kerry
Department of Community Health Sciences, St George's, University of London, UK
J Hypertens 23:1645-51. 2005..CONCLUSIONS: The relationship between BP and BMI is not linear, and is possibly sigmoid, but this may vary between subgroups... - Do statins reduce blood pressure?: a meta-analysis of randomized, controlled trialsPasquale Strazzullo
Department of Clinical and Experimental Medicine, Federico II University Medical School, Naples, Italy
Hypertension 49:792-8. 2007..In conclusion, statin therapy has a relatively small but statistically significant and clinically meaningful effect on blood pressure... - Incidence of hypertension in individuals with different blood pressure salt-sensitivity: results of a 15-year follow-up studyGianvincenzo Barba
Epidemiology and Population Genetics, Institute of Food Sciences, CNR, Avellino, Italy
J Hypertens 25:1465-71. 2007.... - Abnormalities of renal sodium handling in the metabolic syndrome. Results of the Olivetti Heart StudyPasquale Strazzullo
Department of Clinical and Experimental Medicine, Federico II Medical School, University of Naples, Italy
J Hypertens 24:1633-9. 2006.... - Pilot study of potential barriers to blood pressure control in patients with inadequately controlled hypertensionSally C Dean
Department of Community Health Sciences, St George s, University of London, London, UK
Fam Pract 24:259-62. 2007..Most people with high blood pressure (BP) are managed in primary care, but BP control is often inadequate... - Energy cannot be created nor destroyedFrancesco P Cappuccio
Nutr Metab Cardiovasc Dis 16:e11; author reply e13-4. 2006 - Variant of SCN5A sodium channel implicated in risk of cardiac arrhythmiaIgor Splawski
Department of Cardiology, Children s Hospital, Harvard Medical School and Howard Hughes Medical Institute, Boston, MA 02115, USA
Science 297:1333-6. 2002..However, Y1102 may be a useful molecular marker for the prediction of arrhythmia susceptibility in the context of additional acquired risk factors such as the use of certain medications... - Behavioural counselling to increase consumption of fruit and vegetables in low income adults: randomised trialAndrew Steptoe
Department of Epidemiology and Public Health, University College London, London WC1E 6BT
BMJ 326:855. 2003..To measure the effect of brief behavioural counselling in general practice on patients' consumption of fruit and vegetables in adults from a low income population... - Soluble adhesion molecules and coronary heart diseaseFrancesco P Cappuccio
Lancet 359:526-7. 2002 - Commentary: epidemiological transition, migration, and cardiovascular diseaseFrancesco P Cappuccio
Department of Community Health Sciences, St George's Hospital Medical School, Cranmer Terrace, London SW17 0RE, UK
Int J Epidemiol 33:387-8. 2004 - Cellular adhesion molecules and blood pressure: interaction with sex in a multi-ethnic populationMichelle A Miller
Department of Community Health Sciences, St George s Hospital Medical School, London, UK
J Hypertens 22:705-11. 2004..To clarify the association between blood pressure and four different adhesion molecules, adjusting for potential confounders, in men and women from different ethnic origins... - Common variants in the TCF7L2 gene and predisposition to type 2 diabetes in UK European Whites, Indian Asians and Afro-Caribbean men and womenSteve E Humphries
Department of Medicine, Centre for Cardiovascular Genetics, British Heart Foundation Laboratories, Royal Free and University College Medical School, London, WC1E 6JF, UK
J Mol Med (Berl) 84:1005-14. 2006..17) and haplotype frequencies differed markedly in this group. These results extend previous observations to other ethnic groups, and strongly confirm that TCF7L2 genotype is a major risk factor for development of T2D... - The challenges of cross-national research in primary health care across EuropeSally C Dean
Department of Community Health Sciences, St George's Hospital Medical School, London, UK
Fam Pract 22:341-6. 2005 - Salt and cardiovascular diseaseFrancesco P Cappuccio
BMJ 334:859-60. 2007 - Genetic variants of Y chromosome are associated with a protective lipid profile in black menPaola Russo
Unit of Epidemiology and Population Genetics, Institute of Food Sciences, CNR, via Roma 52A C, 83100, Avellino, Italy
Arterioscler Thromb Vasc Biol 28:1569-74. 2008.... - Does the effect of behavioral counseling on fruit and vegetable intake vary with stage of readiness to change?Linda Perkins-Porras
Department of Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK
Prev Med 40:314-20. 2005..We tested the hypothesis that behavioral counseling would overcome the greater obstacles to change in precontemplators and contemplators compared with those initially in the preparation stage... - Brief lifestyle interventions for hypertension: opportunity to provide useful information has been missedFrancesco P Cappuccio
BMJ 329:111; author reply 111-2. 2004 - Quality of life and self-rated health in relation to changes in fruit and vegetable intake and in plasma vitamins C and E in a randomised trial of behavioural and nutritional education counsellingAndrew Steptoe
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Br J Nutr 92:177-84. 2004..Increases in fruit and vegetable intake and plasma vitamin levels may stimulate beneficial changes in physical health status in socio-economically deprived adults... - Genetic variations at the endocannabinoid type 1 receptor gene (CNR1) are associated with obesity phenotypes in menPaola Russo
Unit of Epidemiology and Population Genetics, Institute of Food Sciences, Consiglio Nazionale delle Ricerche, via Roma 52A C, Avellino, Italy
J Clin Endocrinol Metab 92:2382-6. 2007..The endocannabinoid system modulates food intake and body weight in animal models. Treatment with the cannabinoid type 1 receptor blocker, rimonabant, reduces body weight in obese individuals... - For the patient. How much salt is used in Ashanti, West Africa?Sally M Kerry
Ethn Dis 15:150-1. 2005