Marion K Campbell

Summary

Affiliation: University of Aberdeen
Country: UK

Publications

  1. ncbi request reprint Determinants of the intracluster correlation coefficient in cluster randomized trials: the case of implementation research
    Marion K Campbell
    Health Services Research Unit, University of Aberdeen, Foresterhill, UK
    Clin Trials 2:99-107. 2005
  2. pmc Developing the specifications of an open angle glaucoma screening intervention in the United Kingdom: a Delphi approach
    Susan E Campbell
    School of Nursing Sciences, Edith Cavell Building, University of East Anglia, Norwich Research Park, Norwich, UK
    BMC Health Serv Res 12:447. 2012
  3. pmc A pragmatic multi-centre randomised controlled trial of fluid loading in high-risk surgical patients undergoing major elective surgery--the FOCCUS study
    Brian H Cuthbertson
    Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Room D132, Toronto, ON M4N 3M5, Canada
    Crit Care 15:R296. 2011
  4. pmc A study of the perceived risks, benefits and barriers to the use of SDD in adult critical care units (the SuDDICU study)
    B H Cuthbertson
    Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Av, Toronto, Ontario, Canada
    Trials 11:117. 2010
  5. pmc A pragmatic multi-centre randomised controlled trial of fluid loading and level of dependency in high-risk surgical patients undergoing major elective surgery: trial protocol
    Brian H Cuthbertson
    Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Trials 11:41. 2010
  6. pmc A pragmatic randomised, controlled trial of intensive care follow up programmes in improving longer-term outcomes from critical illness. The PRACTICAL study
    Brian H Cuthbertson
    Health Service Research Unit, Health Sciences Building, University of Aberdeen, Foresterhill, Aberdeen, UK
    BMC Health Serv Res 7:116. 2007
  7. pmc Protocol for stage 2 of the GaP study (genetic testing acceptability for Paget's disease of bone): a questionnaire study to investigate whether relatives of people with Paget's disease would accept genetic testing and preventive treatment if they were ava
    Anne L Langston
    Edinburgh Clinical Trials Unit, University of Edinburgh, Queens Medical Research Institute, Room E1, 16, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK
    BMC Health Serv Res 8:116. 2008
  8. pmc Intracluster correlation coefficients in cluster randomized trials: empirical insights into how should they be reported
    Marion K Campbell
    Health Services Research Unit, University of Aberdeen, Aberdeen, UK
    BMC Med Res Methodol 4:9. 2004
  9. ncbi request reprint [The CONSORT statement for cluster randomised trials]
    Marion K Campbell
    Health Services Research Unit, University of Aberdeen, Aberdeen, Reino Unido
    Med Clin (Barc) 125:28-31. 2005
  10. pmc Developing a placebo-controlled trial in surgery: issues of design, acceptability and feasibility
    M K Campbell
    Health Services Research Unit, University of Aberdeen, Aberdeen, UK
    Trials 12:50. 2011

Detail Information

Publications53

  1. ncbi request reprint Determinants of the intracluster correlation coefficient in cluster randomized trials: the case of implementation research
    Marion K Campbell
    Health Services Research Unit, University of Aberdeen, Foresterhill, UK
    Clin Trials 2:99-107. 2005
    ..This study demonstrates that ICCs are sensitive to a number of trial factors, particularly setting and outcome type. These factors must be considered when planning such cluster randomized trials...
  2. pmc Developing the specifications of an open angle glaucoma screening intervention in the United Kingdom: a Delphi approach
    Susan E Campbell
    School of Nursing Sciences, Edith Cavell Building, University of East Anglia, Norwich Research Park, Norwich, UK
    BMC Health Serv Res 12:447. 2012
    ....
  3. pmc A pragmatic multi-centre randomised controlled trial of fluid loading in high-risk surgical patients undergoing major elective surgery--the FOCCUS study
    Brian H Cuthbertson
    Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Room D132, Toronto, ON M4N 3M5, Canada
    Crit Care 15:R296. 2011
    ..Fluid strategies may impact on patient outcomes in major elective surgery. We aimed to study the effectiveness and cost-effectiveness of pre-operative fluid loading in high-risk surgical patients undergoing major elective surgery...
  4. pmc A study of the perceived risks, benefits and barriers to the use of SDD in adult critical care units (the SuDDICU study)
    B H Cuthbertson
    Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Av, Toronto, Ontario, Canada
    Trials 11:117. 2010
    ..Describe barriers to SDD implementation and 3. Identify what further evidence is required before full scale clinical implementation would be considered appropriate and feasible...
  5. pmc A pragmatic multi-centre randomised controlled trial of fluid loading and level of dependency in high-risk surgical patients undergoing major elective surgery: trial protocol
    Brian H Cuthbertson
    Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Trials 11:41. 2010
    ..We propose a pragmatic multi-centre randomised controlled trial of level of dependency and pre-operative fluid therapy in high-risk surgical patients undergoing major elective surgery...
  6. pmc A pragmatic randomised, controlled trial of intensive care follow up programmes in improving longer-term outcomes from critical illness. The PRACTICAL study
    Brian H Cuthbertson
    Health Service Research Unit, Health Sciences Building, University of Aberdeen, Foresterhill, Aberdeen, UK
    BMC Health Serv Res 7:116. 2007
    ....
  7. pmc Protocol for stage 2 of the GaP study (genetic testing acceptability for Paget's disease of bone): a questionnaire study to investigate whether relatives of people with Paget's disease would accept genetic testing and preventive treatment if they were ava
    Anne L Langston
    Edinburgh Clinical Trials Unit, University of Edinburgh, Queens Medical Research Institute, Room E1, 16, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK
    BMC Health Serv Res 8:116. 2008
    ..Illness representations are examined using Leventhal's Common Sense Self-Regulation Model while cognitions about treatment behaviours (acceptance of testing and treatment uptake) are conceptualised within the Theory of Planned Behaviour...
  8. pmc Intracluster correlation coefficients in cluster randomized trials: empirical insights into how should they be reported
    Marion K Campbell
    Health Services Research Unit, University of Aberdeen, Aberdeen, UK
    BMC Med Res Methodol 4:9. 2004
    ..Similarly, the need for appropriate standards of reporting of cluster trials is more widely acknowledged...
  9. ncbi request reprint [The CONSORT statement for cluster randomised trials]
    Marion K Campbell
    Health Services Research Unit, University of Aberdeen, Aberdeen, Reino Unido
    Med Clin (Barc) 125:28-31. 2005
    ..In this paper we review the CONSORT extension to cluster randomised trials, outlining the special features of the cluster randomised trial which must be considered...
  10. pmc Developing a placebo-controlled trial in surgery: issues of design, acceptability and feasibility
    M K Campbell
    Health Services Research Unit, University of Aberdeen, Aberdeen, UK
    Trials 12:50. 2011
    ....
  11. pmc CONSORT statement: extension to cluster randomised trials
    Marion K Campbell
    Health Services Research Unit, University of Aberdeen, Aberdeen, AB25 2ZD
    BMJ 328:702-8. 2004
  12. ncbi request reprint Sample size calculator for cluster randomized trials
    Marion K Campbell
    Health Services Research Unit, University of Aberdeen, Polwarth Building Foresterhill, Aberdeen, Scotland AB25 2ZD UK
    Comput Biol Med 34:113-25. 2004
    ..A sample size calculator is presented for calculating appropriate sample sizes for cluster trials, whilst allowing the implications of both methods of inflation to be considered...
  13. ncbi request reprint Cluster trials in implementation research: estimation of intracluster correlation coefficients and sample size
    M K Campbell
    Health Services Research Unit, University of Aberdeen, Aberdeen, UK
    Stat Med 20:391-9. 2001
    ....
  14. pmc Effect of multivitamin and multimineral supplementation on cognitive function in men and women aged 65 years and over: a randomised controlled trial
    Geraldine McNeill
    Department of Environmental and Occupational Medicine, University of Aberdeen, Foresterhill, Aberdeen, UK
    Nutr J 6:10. 2007
    ..We examined the effect of daily supplementation with 11 vitamins and 5 minerals on cognitive function in older adults to assess the possibility that this could help to prevent cognitive decline...
  15. pmc Protocol for stage 1 of the GaP study (Genetic testing acceptability for Paget's disease of bone): an interview study about genetic testing and preventive treatment: would relatives of people with Paget's disease want testing and treatment if they were av
    Anne L Langston
    Health Services Research Unit, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen, AB25 2ZD, UK
    BMC Health Serv Res 6:71. 2006
    ..The Theory of Planned Behaviour is a theoretical model that predicts behaviours from people's beliefs about the consequences, social pressures and perceived control over the behaviour, including uptake of treatment...
  16. pmc Investigating the relationship between predictability and imbalance in minimisation: a simulation study
    Gladys C McPherson
    Health Services Research Unit, University of Aberdeen, Health Sciences Building, 3rd Floor Foresterhill, Aberdeen, AB25 2ZD, UK
    Trials 14:86. 2013
    ....
  17. doi request reprint Long-term follow-up for mortality and cancer in a randomized placebo-controlled trial of vitamin D(3) and/or calcium (RECORD trial)
    Alison Avenell
    Health Services Research Unit, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK
    J Clin Endocrinol Metab 97:614-22. 2012
    ..Vitamin D or calcium supplementation may have effects on vascular disease and cancer...
  18. pmc Reasons for participating in randomised controlled trials: conditional altruism and considerations for self
    Sharon K McCann
    Health Services Research Unit, University of Aberdeen, Aberdeen, UK
    Trials 11:31. 2010
    ..The idea that altruistic-type motives are important for trial participation is understandably widespread, but recent studies suggest considerations of personal benefit can influence participation decisions in various ways...
  19. pmc Simple imputation methods were inadequate for missing not at random (MNAR) quality of life data
    Shona Fielding
    Department of Public Health, University of Aberdeen, UK
    Health Qual Life Outcomes 6:57. 2008
    ..The objective was to use this unique feature to evaluate possible missingness mechanisms and to assess the accuracy of simple imputation methods...
  20. ncbi request reprint The effects of an open design on trial participant recruitment, compliance and retention--a randomized controlled trial comparison with a blinded, placebo-controlled design
    Alison Avenell
    Health Services Research Unit, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK
    Clin Trials 1:490-8. 2004
    ..In randomized trials there may be no overriding reason whether or not to have a placebo control...
  21. doi request reprint Meaning behind measurement: self-comparisons affect responses to health-related quality of life questionnaires
    Clare Robertson
    Health Services Research Unit, University of Aberdeen, Aberdeen, AB25 22D, UK
    Qual Life Res 18:221-30. 2009
    ..This study investigated how an elderly population living with a chronic metabolic bone disorder evaluated self-reported quality of life...
  22. ncbi request reprint The views of health care professionals about selective decontamination of the digestive tract: An international, theoretically informed interview study
    Eilidh M Duncan
    Aberdeen Health Psychology Group, Health Services Research Unit, University of Aberdeen, Aberdeen, UK Health Services Research Unit, University of Aberdeen, Aberdeen, UK
    J Crit Care 29:634-40. 2014
    ..Uptake of SDD is low and remains controversial. This study applied the theoretical domains framework to assess intensive care unit clinicians' views about SDD in regions with limited or no adoption of SDD...
  23. ncbi request reprint Factors influencing the participation of older people in clinical trials - data analysis from the MAVIS trial
    P Fearn
    Centre of Academic, Primary Care, University of Aberdeen, Foresterhill Health Centre, Aberdeen, AB25 2AY, UK
    J Nutr Health Aging 14:51-6. 2010
    ..Older people are less likely to be included in clinical trials. Little is known about factors influencing older people's decisions about participating in clinical trials...
  24. pmc Minimal access surgery compared with medical management for chronic gastro-oesophageal reflux disease: UK collaborative randomised trial
    Adrian M Grant
    Health Services Research Unit, Health Sciences Building, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD
    BMJ 337:a2664. 2008
    ..To determine the relative benefits and risks of laparoscopic fundoplication surgery as an alternative to long term drug treatment for chronic gastro-oesophageal reflux disease (GORD)...
  25. ncbi request reprint Low dietary potassium intakes and high dietary estimates of net endogenous acid production are associated with low bone mineral density in premenopausal women and increased markers of bone resorption in postmenopausal women
    Helen M Macdonald
    Department of Medicine and Therapeutics, University of Aberdeen, Medical School Buildings, Aberdeen, United Kingdom
    Am J Clin Nutr 81:923-33. 2005
    ..Algorithms based on dietary intakes of key nutrients can be used to approximate net endogenous acid production (NEAP) and to explore the association between dietary acidity and bone health...
  26. ncbi request reprint Influence of weight and weight change on bone loss in perimenopausal and early postmenopausal Scottish women
    Helen M Macdonald
    Department of Medicine and Therapeutics, University of Aberdeen, Medical School Buildings, Foresterhill, Aberdeen, AB25 2ZD, UK
    Osteoporos Int 16:163-71. 2005
    ..Postmenopausal women not taking HRT should be made aware that low body weight or losing weight during this particularly vulnerable period may worsen bone loss...
  27. ncbi request reprint Nutritional associations with bone loss during the menopausal transition: evidence of a beneficial effect of calcium, alcohol, and fruit and vegetable nutrients and of a detrimental effect of fatty acids
    Helen M Macdonald
    Department of Medicine and Therapeutics, University of Aberdeen, United Kingdom
    Am J Clin Nutr 79:155-65. 2004
    ..The menopausal transition is characterized by rapid bone loss. Few data exist on the role of nutrition...
  28. ncbi request reprint Age-restricted cervical screening: HPV testing at age 50 identifies a high risk group for cervical disease
    M E Cruickshank
    Wellbeing Center for the Prevention of Cervical Cancer, Aberdeen Maternity Hospital, University of Aberdeen, Aberdeen, UK
    Int J Gynecol Cancer 12:735-40. 2002
    ..These findings suggest that HPV testing could be a valuable means of identifying the small proportion of women still at risk after 50, and of releasing health care resources...
  29. ncbi request reprint Comparing outcomes in renal replacement therapy: how should we correct for case mix?
    I H Khan
    Department of Medicine and Therapeutics and the Renal Unit, Foresterhill, Aberdeen, Scotland
    Am J Kidney Dis 31:473-8. 1998
    ....
  30. pmc Neonatal examination and screening trial (NEST): a randomised, controlled, switchback trial of alternative policies for low risk infants
    C M Glazener
    Health Services Research Unit, Polwarth Building, Aberdeen AB25 2ZD
    BMJ 318:627-31. 1999
    ..To evaluate the effectiveness of one rather than two hospital neonatal examinations in detection of abnormalities. Design: Randomised controlled switchback trial...
  31. ncbi request reprint Systematic review of the long-term effects and economic consequences of treatments for obesity and implications for health improvement
    A Avenell
    Heath Services Unit, University of Aberdeen, UK
    Health Technol Assess 8:iii-iv, 1-182. 2004
    ..To undertake a systematic review of the long-term effects of obesity treatments on body weight, risk factors for disease, and disease...
  32. ncbi request reprint What interventions should we add to weight reducing diets in adults with obesity? A systematic review of randomized controlled trials of adding drug therapy, exercise, behaviour therapy or combinations of these interventions
    A Avenell
    Health Services Research Unit, University of Aberdeen, Foresterhill, Aberdeen, UK
    J Hum Nutr Diet 17:293-316. 2004
    ..Evidence is needed for the effectiveness of interventions given with reducing diets for obese adults: drug therapy, exercise, or behaviour therapy...
  33. ncbi request reprint What are the long-term benefits of weight reducing diets in adults? A systematic review of randomized controlled trials
    A Avenell
    Health Services Research Unit, University of Aberdeen, Foresterhill, Aberdeen, UK
    J Hum Nutr Diet 17:317-35. 2004
    ..Evidence is needed for the best long-term diet for weight loss, and improvement in cardiac risk and disease in obese adults...
  34. ncbi request reprint Longitudinal changes in weight in perimenopausal and early postmenopausal women: effects of dietary energy intake, energy expenditure, dietary calcium intake and hormone replacement therapy
    H M Macdonald
    Department of Medicine and Therapeutics, University of Aberdeen, Medical School Buildings, Foresterhill, Aberdeen, UK
    Int J Obes Relat Metab Disord 27:669-76. 2003
    ....
  35. pmc Use of randomisation in clinical trials: a survey of UK practice
    Gladys C McPherson
    Health Services Research Unit, University of Aberdeen, 3rd Floor, Foresterhill, Aberdeen, AB25 2ZD, UK
    Trials 13:198. 2012
    ..However, there is uncertainty as to which is the most preferred method of randomisation in any given setting and to what extent more complex methods are actually being implemented in the field...
  36. pmc Using a business model approach and marketing techniques for recruitment to clinical trials
    Alison M McDonald
    Health Services Research Unit, University of Aberdeen, Health Sciences Building, Foresterhill, Aberdeen AB252ZD, UK
    Trials 12:74. 2011
    ..We review what is known about interventions to improve recruitment to trials. We describe a proposed business approach to trials and discuss the implementation of using a business model, using insights gained from three case studies...
  37. pmc A centralised public information resource for randomised trials: a scoping study to explore desirability and feasibility
    Anne L Langston
    University of Aberdeen, Aberdeen, UK
    BMC Health Serv Res 5:39. 2005
    ..An information resource about on-going clinical trials designed for potential and current participants could help overcome some of these problems...
  38. ncbi request reprint An integrated approach to consumer representation and involvement in a multicentre randomized controlled trial
    Anne L Langston
    Health Services Research Unit, University of Aberdeen, Aberdeen, UK
    Clin Trials 2:80-7. 2005
    ..Adoption of such an approach in other trials may yield significant improvements in recruitment and quality of participant information flow. There are, however, resource implications for both parties...
  39. doi request reprint A cost-utility analysis of microwave endometrial ablation versus thermal balloon endometrial ablation
    Mary M Kilonzo
    Health Economics Research Unit, University of Aberdeen, UK
    Value Health 13:528-34. 2010
    ..To evaluate the cost-effectiveness of microwave endometrial ablation (MEA) and thermal balloon endometrial ablation (TBALL) for heavy menstrual bleeding...
  40. ncbi request reprint COL1A1 Sp1 polymorphism predicts perimenopausal and early postmenopausal spinal bone loss
    H M Macdonald
    Department of Medicine and Therapeutics, University of Aberdeen, Foresterhill, United Kingdom
    J Bone Miner Res 16:1634-41. 2001
    ..0%), weight (5.0%), and baseline BMD (2.8%). We conclude that women homozygous for the Sp1 polymorphism are at significantly increased risk of excess rates of bone loss at the spine, but this effect may be nullified by the use of HRT...
  41. ncbi request reprint The method of minimization for allocation to clinical trials. a review
    Neil W Scott
    Department of Public Health, University of Aberdeen, Aberdeen, UK
    Control Clin Trials 23:662-74. 2002
    ..From the evidence presented in this review, we believe minimization to be a highly effective allocation method and recommend its wider adoption in the conduct of randomized controlled trials...
  42. pmc Effect of multivitamin and multimineral supplements on morbidity from infections in older people (MAVIS trial): pragmatic, randomised, double blind, placebo controlled trial
    Alison Avenell
    Health Services Research Unit, School of Medicine, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD
    BMJ 331:324-9. 2005
    ..To examine whether supplementation with multivitamins and multiminerals influences self reported days of infection, use of health services, and quality of life in people aged 65 or over...
  43. ncbi request reprint Comparison of four methods for assessing the importance of attitudinal beliefs: an international Delphi study in intensive care settings
    Jill J Francis
    Health Psychology Group, University of Aberdeen, UK Health Services Research Unit, University of Aberdeen, UK
    Br J Health Psychol 19:274-91. 2014
    ..SDD improves infection rates among critically ill patients, yet uptake in intensive care units is low internationally...
  44. doi request reprint Determining information for inclusion in a decision-support intervention for clinical trial participation: a modified Delphi approach
    Katie Gillies
    aHealth Services Research Unit, University of Aberdeen, Aberdeen, UK
    Clin Trials 10:967-76. 2013
    ..There is a lack of evidence about what information is deemed important to support decisions about informed consent for clinical trials, and whether different groups agree on the information for inclusion...
  45. ncbi request reprint Low back pain: influence of early MR imaging or CT on treatment and outcome--multicenter randomized trial
    Fiona J Gilbert
    Department of Radiology, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, Scotland
    Radiology 231:343-51. 2004
    ..To establish whether early use of magnetic resonance (MR) imaging or computed tomography (CT) influences treatment and outcome of patients with low back pain (LBP) and whether it is cost-effective...
  46. pmc Promoting public awareness of randomised clinical trials using the media: the 'Get Randomised' campaign
    Isla S Mackenzie
    Medicines Monitoring Unit MEMO, University of Dundee, Dundee and Health Services Research Unit, University of Aberdeen, Aberdeen, UK
    Br J Clin Pharmacol 69:128-35. 2010
    ..8, 3.1%; P= 0.92]. CONCLUSIONS It is possible to raise public awareness of clinical research using the media, but further efforts may be required to influence individuals' decisions to take part in clinical research...
  47. ncbi request reprint Issues in data monitoring and interim analysis of trials
    A M Grant
    Health Services Research Unit, University of Aberdeen, UK
    Health Technol Assess 9:1-238, iii-iv. 2005
    ..To address issues about data monitoring committees (DMCs) for randomised controlled trials (RCTs)...
  48. ncbi request reprint Clinical determinants of quality of life in Paget's disease of bone
    A L Langston
    Health Services Research Unit, University of Aberdeen, Aberdeen, AB25 22D, United Kingdom
    Calcif Tissue Int 80:1-9. 2007
    ..The lack of correlation between ALP and quality of life observed in this study emphasizes the importance of addressing quality-of-life issues when treating PDB and not just focussing on response of ALP levels...
  49. ncbi request reprint Does early imaging influence management and improve outcome in patients with low back pain? A pragmatic randomised controlled trial
    F J Gilbert
    Department of Radiology, University of Aberdeen, UK
    Health Technol Assess 8:iii, 1-131. 2004
    ..To establish whether the early use of sophisticated imaging techniques influences the clinical management and outcome of patients with low back pain (LBP) and whether it is cost-effective...
  50. ncbi request reprint The prevalence of prophylaxis for deep vein thrombosis in acute hospital trusts
    S E Campbell
    Health Services Research Unit, University of Aberdeen, UK
    Int J Qual Health Care 13:309-16. 2001
    ..Further research is needed to establish whether rates are equally high in other conditions, and whether the high prophylaxis rates are due to clinical effectiveness initiatives...
  51. doi request reprint Effectiveness and cost-effectiveness of arthroscopic lavage in the treatment of osteoarthritis of the knee: a mixed methods study of the feasibility of conducting a surgical placebo-controlled trial (the KORAL study)
    M K Campbell
    Health Services Research Unit, University of Aberdeen, Aberdeen, UK
    Health Technol Assess 14:1-180. 2010
    ....
  52. ncbi request reprint Lower estimates of net endogenous non-carbonic acid production are positively associated with indexes of bone health in premenopausal and perimenopausal women
    Susan A New
    Centre for Nutrition and Food Safety, School of Biomedical and Molecular Sciences, University of Surrey, Guildford, United Kingdom
    Am J Clin Nutr 79:131-8. 2004
    ..Estimation of the net rate of endogenous non-carbonic acid production (NEAP) from dietary protein and potassium content enables exploration of the effects of dietary acidity or alkalinity on bone...
  53. ncbi request reprint The key role of micronutrients
    Alison Avenell
    Clin Nutr 26:159; author reply 160. 2007