H Campbell

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. pmc A randomised controlled trial of breast cancer genetics services in South East Scotland: psychological impact
    A Fry
    Cancer Research UK, Edinburgh Oncology Unit, Western General Hospital, Crewe Road South, Edinburgh EH4 2XR, UK
    Br J Cancer 89:653-9. 2003
  2. pmc Patient satisfaction with two different models of cancer genetic services in south-east Scotland
    S Holloway
    Department of Clinical Genetics, Molecular Medicine Centre, Western General Hospital, Crewe Road South, Edinburgh EH4 2XU, UK
    Br J Cancer 90:582-9. 2004
  3. pmc The effect of Haemophilus influenzae type b and pneumococcal conjugate vaccines on childhood pneumonia incidence, severe morbidity and mortality
    Evropi Theodoratou
    Public Health Sciences, University of Edinburgh, Edinburgh, UK
    Int J Epidemiol 39:i172-85. 2010
  4. pmc Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration
    Morad Ansari
    MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK
    Hum Mol Genet 22:4857-69. 2013
  5. pmc The effect of case management on childhood pneumonia mortality in developing countries
    Evropi Theodoratou
    Public Health Sciences, University of Edinburgh, Edinburgh, UK
    Int J Epidemiol 39:i155-71. 2010
  6. pmc Systematic review of birth cohort studies in South East Asia and Eastern Mediterranean regions
    Rachel McKinnon
    Centre for Population Health Sciences and Global Health Academy, University of Edinburgh, Scotland, UK
    J Glob Health 1:59-71. 2011
  7. pmc Aetiology of community-acquired neonatal sepsis in low and middle income countries
    Donald Waters
    Centre for Population Health Sciences and Global Health Academy, The University of Edinburgh, Scotland, UK
    J Glob Health 1:154-70. 2011
  8. pmc Estimating the incidence of colorectal cancer in Sub-Saharan Africa: A systematic analysis
    Alice Graham
    Centre for Population Health Sciences and Global Health Academy, The University of Edinburgh Medical School, Edinburgh, Scotland, UK
    J Glob Health 2:20404. 2012
  9. pmc Statin use and association with colorectal cancer survival and risk: case control study with prescription data linkage
    Fatim Lakha
    Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, UK
    BMC Cancer 12:487. 2012
  10. pmc Measuring coverage in MNCH: challenges in monitoring the proportion of young children with pneumonia who receive antibiotic treatment
    Harry Campbell
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS Med 10:e1001421. 2013

Detail Information

Publications71

  1. pmc A randomised controlled trial of breast cancer genetics services in South East Scotland: psychological impact
    A Fry
    Cancer Research UK, Edinburgh Oncology Unit, Western General Hospital, Crewe Road South, Edinburgh EH4 2XR, UK
    Br J Cancer 89:653-9. 2003
    ..Therefore, decisions regarding the implementation of the novel community-based service should be based on the resources required and client satisfaction with the service...
  2. pmc Patient satisfaction with two different models of cancer genetic services in south-east Scotland
    S Holloway
    Department of Clinical Genetics, Molecular Medicine Centre, Western General Hospital, Crewe Road South, Edinburgh EH4 2XU, UK
    Br J Cancer 90:582-9. 2004
    ..The rapidly rising demand for these services suggests that the evaluation of further new models needs to continue to be given priority to guide the development of cancer genetic services...
  3. pmc The effect of Haemophilus influenzae type b and pneumococcal conjugate vaccines on childhood pneumonia incidence, severe morbidity and mortality
    Evropi Theodoratou
    Public Health Sciences, University of Edinburgh, Edinburgh, UK
    Int J Epidemiol 39:i172-85. 2010
    ....
  4. pmc Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration
    Morad Ansari
    MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK
    Hum Mol Genet 22:4857-69. 2013
    ..The results are most consistent with a regulatory locus within a 32 kb region of the CFH gene, with a major effect on plasma CFH concentration and AMD susceptibility. ..
  5. pmc The effect of case management on childhood pneumonia mortality in developing countries
    Evropi Theodoratou
    Public Health Sciences, University of Edinburgh, Edinburgh, UK
    Int J Epidemiol 39:i155-71. 2010
    ....
  6. pmc Systematic review of birth cohort studies in South East Asia and Eastern Mediterranean regions
    Rachel McKinnon
    Centre for Population Health Sciences and Global Health Academy, University of Edinburgh, Scotland, UK
    J Glob Health 1:59-71. 2011
    ..This review summarises the methodologies and main outcomes of longitudinal studies of pre-school children (0 to 59 months) in the World Health Organization's South East Asia (SEA) and Eastern Mediterranean (EM) Regions...
  7. pmc Aetiology of community-acquired neonatal sepsis in low and middle income countries
    Donald Waters
    Centre for Population Health Sciences and Global Health Academy, The University of Edinburgh, Scotland, UK
    J Glob Health 1:154-70. 2011
    ..This review describes and analyses the bacterial aetiology of community-acquired neonatal sepsis in developing countries...
  8. pmc Estimating the incidence of colorectal cancer in Sub-Saharan Africa: A systematic analysis
    Alice Graham
    Centre for Population Health Sciences and Global Health Academy, The University of Edinburgh Medical School, Edinburgh, Scotland, UK
    J Glob Health 2:20404. 2012
    ..This study analyses the data available to produce an estimate of the incidence of colorectal cancer in Sub-Saharan Africa (SSA)...
  9. pmc Statin use and association with colorectal cancer survival and risk: case control study with prescription data linkage
    Fatim Lakha
    Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, UK
    BMC Cancer 12:487. 2012
    ..Epidemiological studies have reported conflicting associations between statins and CRC risk and there is one published report of the association between statins and CRC survival...
  10. pmc Measuring coverage in MNCH: challenges in monitoring the proportion of young children with pneumonia who receive antibiotic treatment
    Harry Campbell
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS Med 10:e1001421. 2013
    ....
  11. pmc Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis
    Harish Nair
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, Edinburgh, UK
    Lancet 375:1545-55. 2010
    ..We aimed to estimate the global incidence of and mortality from episodes of acute lower respiratory infection (ALRI) due to RSV in children younger than 5 years in 2005...
  12. pmc An evaluation of the emerging vaccines and immunotherapy against staphylococcal pneumonia in children
    Tanvir Huda
    International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    BMC Public Health 11:S27. 2011
    ..Currently there are at least seven vaccine and immunotherapy candidates against S. aureus in the developmental phase targeting both active and passive immunization...
  13. pmc An evaluation of emerging vaccines for childhood meningococcal disease
    Debajeet Choudhuri
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, UK
    BMC Public Health 11:S29. 2011
    ..We aimed to perform a structured assessment of these emerging meningococcal vaccines as a means of reducing global meningococcal disease burden among children under 5 years of age...
  14. pmc An evaluation of oxygen systems for treatment of childhood pneumonia
    Alastair G Catto
    Centre for Population Health Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, UK
    BMC Public Health 11:S28. 2011
    ..This review aims to assess the utility of oxygen systems as a method for reducing childhood mortality from pneumonia...
  15. pmc An evaluation of emerging vaccines for childhood pneumococcal pneumonia
    Julia Webster
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, UK
    BMC Public Health 11:S26. 2011
    ....
  16. pmc An evaluation of the emerging interventions against Respiratory Syncytial Virus (RSV)-associated acute lower respiratory infections in children
    Harish Nair
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, UK
    BMC Public Health 11:S30. 2011
    ..Currently there are several vaccine and immunoprophylaxis candidates against RSV in the developmental phase targeting active and passive immunization...
  17. pmc Preventive zinc supplementation in developing countries: impact on mortality and morbidity due to diarrhea, pneumonia and malaria
    Mohammad Yawar Yakoob
    Division of Women and Child Health, The Aga Khan University, Karachi, Pakistan
    BMC Public Health 11:S23. 2011
    ....
  18. pmc An evaluation of respiratory administration of measles vaccine for prevention of acute lower respiratory infections in children
    Daisy Higginson
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, UK
    BMC Public Health 11:S31. 2011
    ..Aerosolised measles vaccines are now under development with the hope of challenging the delivery factors currently limiting the coverage of the existing vaccine...
  19. pmc Rhegmatogenous retinal detachment in Scotland: research design and methodology
    Danny Mitry
    Princess Alexandra Eye Pavilion, Chalmers Street, Edinburgh, UK
    BMC Ophthalmol 9:2. 2009
    ..The aim of this study is to obtain a first estimate incidence of RRD in Scotland, to estimate the incidence of familial RRD and to describe the known associations of RRD within the study population...
  20. pmc Generation Scotland: the Scottish Family Health Study; a new resource for researching genes and heritability
    Blair H Smith
    University of Aberdeen, Department of General Practice and Primary Care, Foresterhill Health Centre, Westburn Road, Aberdeen, UK
    BMC Med Genet 7:74. 2006
    ....
  21. pmc A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2 with serum creatinine level
    Cristian Pattaro
    Institute of Genetic Medicine, European Academy Bozen Bolzano EURAC, Bolzano, Italy
    BMC Med Genet 11:41. 2010
    ..A substantial proportion of the inter-individual variability in S CR level is explicable by genetic factors...
  22. pmc The Lothian Birth Cohort 1936: a study to examine influences on cognitive ageing from age 11 to age 70 and beyond
    Ian J Deary
    Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, UK
    BMC Geriatr 7:28. 2007
    ..A limitation of many studies is the lack of a sufficiently long period between cognitive assessments to examine determinants. Here, the aim is to examine influences on cognitive ageing between childhood and old age...
  23. pmc Comparative assessment of methods for estimating individual genome-wide homozygosity-by-descent from human genomic data
    Ozren Polasek
    Public Health Sciences, University of Edinburgh, Edinburgh, UK
    BMC Genomics 11:139. 2010
    ..0625) were included in this study. All individuals were genotyped with the Illumina HumanHap300 array with 317,503 SNP markers...
  24. pmc Global initiatives for improving hospital care for children: state of the art and future prospects
    Harry Campbell
    Public Health Sciences, Institute of Genomics and Molecular Medicine, College of Medicine and Vet Medicine University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, United Kingdom
    Pediatrics 121:e984-92. 2008
    ..The challenges remain to bring these and other strategies to scale and to support research into their use, impact, and sustainability in different environments...
  25. ncbi request reprint Commentary: rare alleles, modest genetic effects and the need for collaboration
    H Campbell
    Division of Community Health Sciences, Public Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, UK
    Int J Epidemiol 36:445-8. 2007
  26. ncbi request reprint Effects of genome-wide heterozygosity on a range of biomedically relevant human quantitative traits
    Harry Campbell
    Department of Public Health Sciences, University of Edinburgh, Edinburgh, UK
    Hum Mol Genet 16:233-41. 2007
    ..Other traits, such as age at menarche, IQ and lifespan, which have been changing during the decades of urbanization, may also have been influenced by demographic factors...
  27. pmc Human population structure, genome autozygosity and human health
    Harry Campbell
    Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, UK
    Genome Med 1:91. 2009
    ..The overall outcome is expected to be beneficial for a range of traits associated with human health and disease that show dominance variance...
  28. pmc Referrals of women with a family history of breast cancer from primary care to cancer genetics services in South East Scotland
    H Campbell
    Department of Public Health Sciences, University of Edinburgh Medical School, Teviot Place, Edinburgh EH8 9AG, UK
    Br J Cancer 89:1650-6. 2003
    ..The provision of the clinics within general practice did not result in higher levels of confidence among GPs in managing these women...
  29. pmc Incidence of invasive pneumococcal disease in Scotland, 1988-99
    M H Kyaw
    University of Edinburgh, Public Health Sciences
    Epidemiol Infect 128:139-47. 2002
    ....
  30. doi request reprint Surgical outcome and risk stratification for primary retinal detachment repair: results from the Scottish Retinal Detachment study
    D Mitry
    Clinical Research Fellow in Ophthalmology, Department of Public Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, UK
    Br J Ophthalmol 96:730-4. 2012
    ..To report the early surgical outcome, risk of failure and predictive value of rhegmatogenous retinal detachment (RRD) classification based on all participants in the Scottish Retinal Detachment study...
  31. ncbi request reprint Germline mutation prevalence in the base excision repair gene, MYH, in patients with endometrial cancer
    R A Barnetson
    Colon Cancer Genetics Group, University of Edinburgh Cancer Research Centre and MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK
    Clin Genet 72:551-5. 2007
    ..While not conclusive, this novel and interesting finding provides evidence that bi-allelic germline mutations in MYH may increase susceptibility to endometrial cancer...
  32. doi request reprint The fellow eye in retinal detachment: findings from the Scottish Retinal Detachment Study
    D Mitry
    Department of Public Health Sciences, Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK
    Br J Ophthalmol 96:110-3. 2012
    ..To characterise the predisposing pathology and clinical features in the fellow eyes of patients recruited as part of the Scottish Retinal Detachment Study...
  33. ncbi request reprint Prevalence of family history of colorectal cancer in the general population
    R J Mitchell
    Colon Cancer Genetics Group, University of Edinburgh, Division of Clinical and Molecular Medicine and Medical Research Council Human Genetics Unit, Western General Hospital, Edinburgh, UK
    Br J Surg 92:1161-4. 2005
    ..However, there is a paucity of high-quality data...
  34. pmc Accuracy of reporting of family history of colorectal cancer
    R J Mitchell
    Public Health Sciences, Department of Community Health Sciences, University of Edinburgh, Edinburgh, Scotland, UK
    Gut 53:291-5. 2004
    ..Hence we systematically assessed the accuracy of family history reported at interview compared with actual cancer experience in relatives...
  35. doi request reprint Common genetic variants at the MC4R locus are associated with obesity, but not with dietary energy intake or colorectal cancer in the Scottish population
    A Tenesa
    Colon Cancer Genetics Group, MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, University of Edinburgh, Edinburgh, UK
    Int J Obes (Lond) 33:284-8. 2009
    ..Obesity is a known risk factor for colorectal cancer (CRC) and we hypothesized that there might be a common inherited genetic component...
  36. doi request reprint SNP mistyping in genotyping arrays--an important cause of spurious association in case-control studies
    D Mitry
    Department of Public Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, United Kingdom
    Genet Epidemiol 35:423-6. 2011
    ....
  37. doi request reprint Cascade genetic testing for mismatch repair gene mutations
    R J Mitchell
    Public Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH89AG, UK
    Fam Cancer 7:293-301. 2008
    ..In the absence of robust data from epidemiological studies, these findings can inform decisions about the use of cascade genetic testing for mismatch repair gene mutations...
  38. pmc A survey of vaccine coverage and antibiotic prophylaxis in splenectomised patients in Scotland
    M H Kyaw
    Public Health Sciences, University of Edinburgh, Teviot Place, EH 8 9AG, UK
    J Clin Pathol 55:472-4. 2002
    ..To determine the coverage of vaccine and antibiotic prophylaxis in splenectomised patients in Scotland...
  39. pmc Is it acceptable to approach colorectal cancer patients at diagnosis to discuss genetic testing? A pilot study
    M Porteous
    Department of Clinical Genetics, Molecular Medicine Centre, Western General Hospital, Crewe Road South, Edinburgh EH4 2XU, UK
    Br J Cancer 89:1400-2. 2003
    ..A total of 78% of participants found it highly acceptable to have the information about HNPCC brought to their attention at that time...
  40. ncbi request reprint Estimating human inbreeding coefficients: comparison of genealogical and marker heterozygosity approaches
    A D Carothers
    MRC Human Genetics Unit, Western General Hospital, Edinburgh EH4 2XU, UK
    Ann Hum Genet 70:666-76. 2006
    ..This method could provide useful estimates of average F-values for groups of individuals in population-based studies of the effects of inbreeding/homozygosity on quantitative traits...
  41. ncbi request reprint Prevention of pneumococcal disease in children. Pneumococcal conjugate vaccines: their use globally could have a major impact on public health
    M H Kyaw
    University of Edinburgh, Public Health Sciences, Scotland
    Acta Paediatr 90:473-6. 2001
    ..Thus widespread use of pneumococcal conjugate vaccine could substantially reduce the burden of invasive disease and would have the potential to control the global spread of antibiotic resistance in pneumococci...
  42. ncbi request reprint Mismatch repair genes hMLH1 and hMSH2 and colorectal cancer: a HuGE review
    R J Mitchell
    Department of Public Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, United Kingdom
    Am J Epidemiol 156:885-902. 2002
    ..Population screening for mutation carriers is not currently a feasible option, and mutation analysis remains restricted to either relatives of mutation carriers or colorectal cancer cases selected on the basis of phenotype...
  43. pmc A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants
    E Theodoratou
    Colon Cancer Genetics Group and Academic Coloproctology, MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK
    Br J Cancer 103:1875-84. 2010
    ..We report a large collaborative meta-analysis to assess and refine CRC risk estimates associated with bi-allelic and mono-allelic MUTYH variants and investigate age and sex influence on risk...
  44. pmc Association of MUTYH and colorectal cancer
    A Tenesa
    Colon Cancer Genetics Group, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, UK
    Br J Cancer 95:239-42. 2006
    ..This study underscores the need for large sample sizes in order to identify small gene effects when the disease allele frequency is low...
  45. pmc Non-invasive pneumococcal disease and antimicrobial resistance: vaccine implications
    M H Kyaw
    University of Edinburgh, Public Health Sciences
    Epidemiol Infect 128:21-7. 2002
    ..The availability of conjugated vaccines reinforces the importance of systematic surveillance to determine accurately and regularly the coverage of pneumococcal serogroups and types causing both invasive and non-invasive disease...
  46. ncbi request reprint A capture-recapture model to estimate prevalence of children born in Scotland with developmental eye defects
    H Campbell
    Department of Community Health Sciences, University of Edinburgh, UK
    J Cancer Epidemiol Prev 7:21-8. 2002
    ..Despite this effort, it was recognised that some cases would remain unidentified. Capture-recapture methods could improve the accuracy of the study's birth prevalence estimate...
  47. pmc National study of microphthalmia, anophthalmia, and coloboma (MAC) in Scotland: investigation of genetic aetiology
    D Morrison
    Public Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK
    J Med Genet 39:16-22. 2002
    ..No pathogenic mutations were identified in the OFCD cases. A single PAX6 homeodomain missense mutation was identified in a subject with partial aniridia that had been initially misclassified as coloboma...
  48. ncbi request reprint The epidemiology of rhegmatogenous retinal detachment: geographical variation and clinical associations
    D Mitry
    Princess Alexandra Eye Pavilion, Edinburgh, UK
    Br J Ophthalmol 94:678-84. 2010
    ..Rhegmatogenous retinal detachment (RRD) is a potentially blinding condition. Obtaining an accurate estimate of RRD incidence in the population is essential in understanding the healthcare burden related to this disorder...
  49. ncbi request reprint Guidelines and care pathways for genetic diseases: the Scottish collaborative project on tuberous sclerosis
    N Bradshaw
    Department of Clinical Genetics, Western General Hospital, Edinburgh, Scotland
    Eur J Hum Genet 6:445-58. 1998
    ..In order to facilitate the audit and use of these guidelines a 'Care Pathway' was devised to form the patient records. We describe the process of guideline development for TS and our TS Care Pathway...
  50. ncbi request reprint The contribution of DNA mismatch repair gene defects to the burden of gynecological cancer
    A C Drake
    University of Edinburgh, Edinburgh, United Kingdom
    Int J Gynecol Cancer 13:262-77. 2003
  51. doi request reprint Genetic epidemiology
    J K Dunbar
    Public Health Medicine, Public Health Directorate, NHS Tayside, Kings Cross Hospital, Dundee, Scotland, UK
    J R Coll Physicians Edinb 42:139-41; quiz 142. 2012
    ..Currently large resources for research, such as the UK Biobank project, are being developed which will allow detailed exploration of not only genes but the way their actions are controlled...
  52. pmc Prevalence of autistic spectrum disorders in Lothian, Scotland: an estimate using the "capture-recapture" technique
    M J Harrison
    Dept of Public Health Sciences and Child Life and Health, Reproductive and Developmental Sciences, University of Edinburgh, UK
    Arch Dis Child 91:16-9. 2006
  53. ncbi request reprint Gene-environment interactions--the BioBank UK study
    A F Wright
    MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK
    Pharmacogenomics J 2:75-82. 2002
  54. ncbi request reprint Nucleotide excision repair gene XPD polymorphisms and genetic predisposition to melanoma
    D Tomescu
    Sir Alastair Currie CRC Laboratories, Molecular Medicine Centre, Edinburgh University, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK
    Carcinogenesis 22:403-8. 2001
    ....
  55. ncbi request reprint Primary osteosarcoma of the breast
    K Irshad
    Department of Surgery, Wishaw General Hospital, Scotland, UK
    Breast 12:72-4. 2003
    ..Because there was no evidence of metastasis and adequate local excision, no further treatment was considered necessary and she remains disease free at 39 months...
  56. ncbi request reprint Cancer incidence in eastern Adriatic isolates, Croatia: examples from the islands of Krk, Cres, Losinj, Rab and Pag
    I Rudan
    Department of Medical Statistics, Epidemiology and Medical Informatics, School of Public Health Andrija Stampar, University Medical School, Zagreb, Croatia
    Coll Antropol 23:547-56. 1999
    ..However, it is possible that genetic isolation and inbreeding are important factors. Further investigations of cancer in these isolate populations are warranted to explore these findings further...
  57. ncbi request reprint Inbreeding and nephrolithiasis in Croatian island isolates
    I Rudan
    School of Public Health A Stampar, University Medical School, Zagreb, Croatia
    Coll Antropol 26:11-21. 2002
    ..45 (p<0.05). The study showed that a large number of predominantly recessive genetic factors might mediate the susceptibility to formation of renal stones in humans...
  58. pmc A cross-sectional survey to estimate the prevalence of family history of colorectal, breast and ovarian cancer in a Scottish general practice population
    E Wallace
    Public Health Department, Fife NHS Board, Springfield House, Cupar, Fife, Scotland
    Br J Cancer 91:1575-9. 2004
    ..A simple family history chart or pedigree is one way that a GP can, within the constraints of a GP consultation, determine which patients should be reassured and which referred to the local cancer genetic clinic...
  59. ncbi request reprint Effect of inbreeding and endogamy on occlusal traits in human isolates
    T Lauc
    Institute for Anthropological Research, Zagreb, Croatia
    J Orthod 30:301-8; discussion 297. 2003
    ..Subjects and methods: The sample comprised dental casts of 224 children, aged 7-14 years, from 15 villages of the Island of Hvar, Croatia...
  60. ncbi request reprint Review of the effect of measles vaccination on the epidemiology of SSPE
    H Campbell
    Immunisation Department, Health Protection Agency Centre for Infections, 61 Colindale Avenue, London NW9 5EQ, UK
    Int J Epidemiol 36:1334-48. 2007
    ..We conducted a comprehensive review of the impact of measles immunization on the epidemiology of SSPE and examined epidemiological evidence on whether there was any vaccine-associated risk...
  61. ncbi request reprint Genetic epidemiological studies of eastern Adriatic Island isolates, Croatia: objective and strategies
    I Rudan
    Department of Medical Statistics, Epidemiology and Medical Informatics, School of Public Health Andrija Stampar, University Medical School, Zagreb, Croatia
    Coll Antropol 23:531-46. 1999
    ....
  62. pmc Inbreeding and risk of late onset complex disease
    I Rudan
    J Med Genet 40:925-32. 2003
  63. ncbi request reprint The evidence of mtDNA haplogroup F in a European population and its ethnohistoric implications
    H V Tolk
    Department of Evolutionary Biology, Institute for Molecular and Cell Biology, University of Tartu, Riia 23, 51010 Tartu, Estonia
    Eur J Hum Genet 9:717-23. 2001
    ..The first published phylogenetic analysis of haplogroup F worldwide is presented, applying the median network method, suggesting several scenarios how this maternal lineage may have been added to the Croatian mtDNA pool...
  64. ncbi request reprint Haematological malignancies in childhood in Croatia: investigating the theories of depleted uranium, chemical plant damage and 'population mixing'
    B Labar
    Faculty of Medicine, University of Zagreb, Croatia
    Eur J Epidemiol 19:55-60. 2004
    ..In those counties, the incidence of Hodgkin's lymphoma decreased during and after the war. In Croatia as a whole, decreases in incidence of myeloid leukaemias during war and non-Hodgkin lymphoma after the war were noted...
  65. ncbi request reprint New developments in genetics-knowledge, attitudes and information needs of practice nurses
    C Bankhead
    CRC Primary Care Education Research Group, University of Oxford, UK
    Fam Pract 18:475-86. 2001
    ..There is a need for further education for practice nurses regarding family history information and the new genetics so that this information is managed appropriately...
  66. ncbi request reprint First steps in developing a managed clinical network for vascular services in Lanarkshire
    D Moir
    Lanarkshire Health Board, 14 Beckford Street, Hamilton
    Health Bull (Edinb) 59:405-11. 2001
    ..Further research is required to determine the most appropriate form of leadership for the network, and to identify, more clearly, what is understood by a managed network and what accountability there should be...
  67. pmc Prevalence of moderate penicillin resistant invasive Neisseria meningitidis infection in Scotland, 1994-9
    M H Kyaw
    Scottish Centre for Infection and Environmental Health, Glasgow, UK
    Epidemiol Infect 128:149-56. 2002
    ..Constant surveillance is necessary to monitor the emergence and spread of resistance and to guide appropriate public health interventions in preventing drug resistant meningococci...
  68. ncbi request reprint Inbreeding and learning disability in Croatian island isolates
    I Rudan
    School of Public Health A Stampar, School of Medicine, University of Zagreb, Zagreb, Croatia
    Coll Antropol 26:421-8. 2002
    ..6%. A review of the literature and the results of this study lead to a conclusion that a very large number of predominantly recessive genetic factors might mediate the genetic susceptibility to various forms of LD in these populations...
  69. pmc Influenza and pneumococcal vaccine distribution and use in primary care and hospital settings in Scotland: coverage, practice and policies
    M H Kyaw
    University of Edinburgh, Department of Public Health Services
    Epidemiol Infect 128:445-55. 2002
    ..Forty-five percent of GPs reported having a written policy with set target for influenza vaccination and 11% for pneumococcal vaccination...
  70. pmc Potential interventions for the prevention of childhood pneumonia in developing countries: a systematic review
    B R Kirkwood
    Department of Epidemiology and Population Sciences, London School of Hygiene and Tropical Medicine, England
    Bull World Health Organ 73:793-8. 1995
    ..Calculation of the potential impacts is illustrated and the expected outcomes are also described...
  71. ncbi request reprint Cost-effectiveness of using prognostic information to select women with breast cancer for adjuvant systemic therapy
    C Williams
    Bristol Haematology and Oncology Centre, UK
    Health Technol Assess 10:iii-iv, ix-xi, 1-204. 2006
    ..To investigate the cost-effectiveness of using prognostic information to identify patients with breast cancer who should receive adjuvant therapy...