B J Campbell
Affiliation: University of Liverpool
- Altered glycosylation in inflammatory bowel disease: a possible role in cancer developmentB J Campbell
Glycobiology Group, Henry Wellcome Laboratory of Molecular and Cellular Gastroenterology, Department of Medicine, University of Liverpool, Crown Street, Liverpool, L69 3BX, UK
Glycoconj J 18:851-8. 2001..Consequences of these changes may be relevant not only for cell-surface glycoconjugates but also for intracellular glycoconjugates...
- Increasing the intra-Golgi pH of cultured LS174T goblet-differentiated cells mimics the decreased mucin sulfation and increased Thomsen-Friedenreich antigen (Gal beta1-3GalNac alpha-) expression seen in colon cancerB J Campbell
Glycobiology Group, Gastroenterology Research Unit, Department of Medicine, University of Liverpool, Daulby Street, Liverpool, L69 3GA, UK
Glycobiology 11:385-93. 2001..Intra-Golgi alkalinization affects mucin glycosylation, resulting in decreased mucin sulfation and increased expression of TF antigen, changes that mimic those seen in cancerous and premalignant human colonic epithelium...
- Cell surface-expressed Thomsen-Friedenreich antigen in colon cancer is predominantly carried on high molecular weight splice variants of CD44R Singh
Department of Medicine, University of Liverpool, Daulby Street, Liverpool L69 3GA, UK
Glycobiology 11:587-92. 2001....
- Interaction between bacterial peptides, neutrophils and goblet cells: a possible mechanism for neutrophil recruitment and goblet cell depletion in colitisK Leiper
Gastroenterology Research Unit, Department of Medicine, University of Liverpool, Liverpool L69 3GA
Clin Sci (Lond) 101:395-402. 2001..These findings support the hypothesis that the mucosal inflammation and mucus depletion seen in ulcerative colitis could result from interaction between bacterial peptides and the mucosa...