F Calabi

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi The molecular biology of CD1
    F Calabi
    Institute of Child Health, 30 Guilford St, WC1N 1EH London, UK and MRC Laboratory of Molecular Biology, Hills Rd, Cambridge, CB2 2QH, UK
    Semin Immunol 12:503-9. 2000
  2. ncbi CBFA2T1, a gene rearranged in human leukemia, is a member of a multigene family
    F Calabi
    Cell and Molecular Biology Division, Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, United Kingdom
    Genomics 52:332-41. 1998
  3. ncbi Identification and comparative analysis of a second runx3 promoter
    D Rini
    Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Gene 273:13-22. 2001
  4. ncbi Alternative, out-of-frame runt/MTG8 transcripts are encoded by the derivative (8) chromosome in the t(8;21) of acute myeloid leukemia M2
    J E Tighe
    Department of Haematology, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK
    Blood 84:2115-21. 1994
  5. ncbi Expression of runt in the mouse embryo
    A Simeone
    Department of Haematology, Royal Postgraduate Medical School, Hammersmith Hospital, London, United Kingdom
    Dev Dyn 203:61-70. 1995
  6. pmc Gene targeting reveals a crucial role for MTG8 in the gut
    F Calabi
    Institute of Child Health, London WCIN 1EH, United Kingdom
    Mol Cell Biol 21:5658-66. 2001
  7. pmc Mouse CD1 is distinct from and co-exists with TL in the same thymus
    A Bradbury
    MRC Laboratory of Molecular Biology, Cambridge, UK
    EMBO J 7:3081-6. 1988
  8. ncbi Identification and chromosomal mapping of a third mouse runt-like locus
    F Calabi
    Department of Haematology, Royal Postgraduate Medical School, Hammersmith Hospital, London, United Kingdom
    Genomics 26:607-10. 1995
  9. ncbi Expression of runtB is modulated during chondrocyte differentiation
    P Castagnola
    Laboratorio di Differenziamento Cellulare, Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
    Exp Cell Res 223:215-26. 1996
  10. pmc Structure and expression of the human thymocyte antigens CD1a, CD1b, and CD1c
    L H Martin
    Medical Research Council Laboratory of Molecular Biology, Cambridge, England
    Proc Natl Acad Sci U S A 84:9189-93. 1987

Collaborators

  • A Simeone
  • P P Pompa
  • D Rini
  • R Rinaldi
  • R Chiuri
  • R Cingolani
  • G Maruccio
  • L L del Mercato
  • A Della Torre
  • A Bramanti
  • P Castagnola
  • J E Tighe
  • M Gennari
  • A Daga
  • F Rossi
  • A Gaggero
  • R Cancedda
  • M T Corsetti
  • L H Martin
  • C Milstein
  • M S Neuberger
  • A Bradbury
  • K T Belt
  • C A Bilsland
  • T M Neri
  • F A Lefebvre

Detail Information

Publications15

  1. ncbi The molecular biology of CD1
    F Calabi
    Institute of Child Health, 30 Guilford St, WC1N 1EH London, UK and MRC Laboratory of Molecular Biology, Hills Rd, Cambridge, CB2 2QH, UK
    Semin Immunol 12:503-9. 2000
    ..In this review, we summarize some key results from the molecular study of CD1, with particular reference to their relationship to MHC antigens, and to the existence of two distinct groups of CD1 molecules...
  2. ncbi CBFA2T1, a gene rearranged in human leukemia, is a member of a multigene family
    F Calabi
    Cell and Molecular Biology Division, Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, United Kingdom
    Genomics 52:332-41. 1998
    ..The most NH2-terminal of these is proportionately more conserved among the human polypeptides, presumably due to specific structural/functional constraints...
  3. ncbi Identification and comparative analysis of a second runx3 promoter
    D Rini
    Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Gene 273:13-22. 2001
    ..The conservation of a two-promoter structure and their distinctive pattern of activity support the hypothesis that alternative 5' isoforms subserve unique functions...
  4. ncbi Alternative, out-of-frame runt/MTG8 transcripts are encoded by the derivative (8) chromosome in the t(8;21) of acute myeloid leukemia M2
    J E Tighe
    Department of Haematology, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK
    Blood 84:2115-21. 1994
    ..Thus, runt truncation per se, rather than its fusion to MTG8, may be the crucial leukemogenic event...
  5. ncbi Expression of runt in the mouse embryo
    A Simeone
    Department of Haematology, Royal Postgraduate Medical School, Hammersmith Hospital, London, United Kingdom
    Dev Dyn 203:61-70. 1995
    ..Unambiguous expression in the haemopoietic system could be established for the thymus. The data suggest a pleiotropic role for mammalian runt in embryogenesis...
  6. pmc Gene targeting reveals a crucial role for MTG8 in the gut
    F Calabi
    Institute of Child Health, London WCIN 1EH, United Kingdom
    Mol Cell Biol 21:5658-66. 2001
    ..Levels of factors known to be involved in gut morphogenesis were also unchanged. MTG8 is expressed in the outermost layers of the developing gut from at least E9.5. Thus, MTG8 plays a novel, essential role in the gastrointestinal system...
  7. pmc Mouse CD1 is distinct from and co-exists with TL in the same thymus
    A Bradbury
    MRC Laboratory of Molecular Biology, Cambridge, UK
    EMBO J 7:3081-6. 1988
    ..It is paradoxical that despite the structural similarity between mouse and human CD1, the tissue distribution of human CD1 is closer to TL. The possibility of a functional convergence between MHC molecules and CD1 is discussed...
  8. ncbi Identification and chromosomal mapping of a third mouse runt-like locus
    F Calabi
    Department of Haematology, Royal Postgraduate Medical School, Hammersmith Hospital, London, United Kingdom
    Genomics 26:607-10. 1995
    ..By using a panel of somatic cell hybrids and interspecific backcross mice, we map the novel locus to the telomeric region of mouse chromosome 4...
  9. ncbi Expression of runtB is modulated during chondrocyte differentiation
    P Castagnola
    Laboratorio di Differenziamento Cellulare, Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
    Exp Cell Res 223:215-26. 1996
    ..Moreover, runt polypeptides were demonstrated in chondrocytes both in vivo and in vitro. These results suggest that runt plays a role in chondrogenic differentiation...
  10. pmc Structure and expression of the human thymocyte antigens CD1a, CD1b, and CD1c
    L H Martin
    Medical Research Council Laboratory of Molecular Biology, Cambridge, England
    Proc Natl Acad Sci U S A 84:9189-93. 1987
    ..The general relatedness to major histocompatibility complex class I and class II molecules is significant but low, with no section of higher homology to mouse Tla...
  11. ncbi Reciprocal chromosome translocation between c-myc and immunoglobulin gamma 2b genes
    M S Neuberger
    Nature 305:240-3. 1983
    ..This reciprocal translocation was analysed in DNA from a mouse hybridoma cell line but is shown to be characteristic of the X63Ag8 myeloma parent...
  12. pmc Chromosome translocation activates heterogeneously initiated, bipolar transcription of a mouse c-myc gene
    F Calabi
    EMBO J 4:667-74. 1985
    ..We propose that chromosome translocation activates a cryptic promoter in the first intron and that the heterogeneously initiated, bipolar transcription reflects the absence of a suitably placed TATA box element...
  13. pmc Isolation of CD1 genes: a family of major histocompatibility complex-related differentiation antigens
    L H Martin
    Proc Natl Acad Sci U S A 83:9154-8. 1986
    ..This is the same degree of homology as between either of them and the class II beta 2 domain, which does not bind beta 2-microglobulin. The evolutionary implications of these results are discussed...
  14. ncbi A novel family of human major histocompatibility complex-related genes not mapping to chromosome 6
    F Calabi
    Nature 323:540-3. 1986
    ..We report the isolation of complementary DNA (cDNA) clones encoding a CD1 antigen. These clones reveal a novel family of genes which are MHC-related but are neither equivalent to mouse TL antigens nor linked to the MHC...
  15. ncbi Charge transport in disordered films of non-redox proteins
    P P Pompa
    National Nanotechnology Laboratories of CNR INFM, Technological District ISUFI, University of Lecce, Via per Arnesano, 73100 Lecce, Italy
    J Chem Phys 125:21103. 2006
    ..These results may lead to the implementation of protein-based three-terminal nanodevices and open important new perspectives for a wide range of bioelectronic/biosensing applications...