T J Bussey

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi request reprint Testing long-term memory in animal models of schizophrenia: suggestions from CNTRICS
    Timothy J Bussey
    Department of Experimental Psychology and The MRC and Wellcome Trust Behavioural and Clinical Neuroscience Institute, University of Cambridge, CB2 3EB, UK Electronic address
    Neurosci Biobehav Rev 37:2141-8. 2013
  2. pmc New translational assays for preclinical modelling of cognition in schizophrenia: the touchscreen testing method for mice and rats
    T J Bussey
    Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
    Neuropharmacology 62:1191-203. 2012
  3. ncbi request reprint The role of ventral and orbital prefrontal cortex in conditional visuomotor learning and strategy use in rhesus monkeys (Macaca mulatta)
    T J Bussey
    National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    Behav Neurosci 115:971-82. 2001
  4. ncbi request reprint Memory, perception, and the ventral visual-perirhinal-hippocampal stream: thinking outside of the boxes
    T J Bussey
    Department of Experimental Psychology, University of Cambridge, Cambridge, United Kingdom
    Hippocampus 17:898-908. 2007
  5. ncbi request reprint Impairments in visual discrimination after perirhinal cortex lesions: testing 'declarative' vs. 'perceptual-mnemonic' views of perirhinal cortex function
    Timothy J Bussey
    Section on the Neurobiology of Learning and Memory, Laboratory of Neuropsychology, National Institute of Mental Health, Convent Drive, Building 49, Room 1880, MSC4415, Bethesda, MD 20892, USA
    Eur J Neurosci 17:649-60. 2003
  6. ncbi request reprint Interaction of ventral and orbital prefrontal cortex with inferotemporal cortex in conditional visuomotor learning
    Timothy J Bussey
    Laboratory of Neuropsychology, National Institute of Mental Health, Bethesda, Maryland 20892 4415, USA
    Behav Neurosci 116:703-15. 2002
  7. ncbi request reprint Perirhinal cortex resolves feature ambiguity in complex visual discriminations
    Timothy J Bussey
    Section on the Neurobiology of Learning and Memory, Laboratory of Neuropsychology, National Institute of Mental Health, Convent Drive, Building 49, Room 1880, MSC4415, Bethesda, MD 20892, USA
    Eur J Neurosci 15:365-74. 2002
  8. ncbi request reprint The organization of visual object representations: a connectionist model of effects of lesions in perirhinal cortex
    Timothy J Bussey
    Section on the Neurobiology of Learning and Memory, Laboratory of Neuropsychology, National Institute of Mental Health, Bethesda, MD 20892, USA
    Eur J Neurosci 15:355-64. 2002
  9. pmc The touchscreen cognitive testing method for rodents: how to get the best out of your rat
    Timothy J Bussey
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    Learn Mem 15:516-23. 2008
  10. ncbi request reprint Object memory and perception in the medial temporal lobe: an alternative approach
    Timothy J Bussey
    Dept of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB1 3EB, UK
    Curr Opin Neurobiol 15:730-7. 2005

Detail Information

Publications58

  1. ncbi request reprint Testing long-term memory in animal models of schizophrenia: suggestions from CNTRICS
    Timothy J Bussey
    Department of Experimental Psychology and The MRC and Wellcome Trust Behavioural and Clinical Neuroscience Institute, University of Cambridge, CB2 3EB, UK Electronic address
    Neurosci Biobehav Rev 37:2141-8. 2013
    ..A number of candidate animal paradigms were discussed. Two of these - one for rodents and one for non-human primates - were recommended as particularly promising for further development. ..
  2. pmc New translational assays for preclinical modelling of cognition in schizophrenia: the touchscreen testing method for mice and rats
    T J Bussey
    Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
    Neuropharmacology 62:1191-203. 2012
    ..New tests are being continuously developed, many of which may prove particularly valuable for schizophrenia research...
  3. ncbi request reprint The role of ventral and orbital prefrontal cortex in conditional visuomotor learning and strategy use in rhesus monkeys (Macaca mulatta)
    T J Bussey
    National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    Behav Neurosci 115:971-82. 2001
    ....
  4. ncbi request reprint Memory, perception, and the ventral visual-perirhinal-hippocampal stream: thinking outside of the boxes
    T J Bussey
    Department of Experimental Psychology, University of Cambridge, Cambridge, United Kingdom
    Hippocampus 17:898-908. 2007
    ....
  5. ncbi request reprint Impairments in visual discrimination after perirhinal cortex lesions: testing 'declarative' vs. 'perceptual-mnemonic' views of perirhinal cortex function
    Timothy J Bussey
    Section on the Neurobiology of Learning and Memory, Laboratory of Neuropsychology, National Institute of Mental Health, Convent Drive, Building 49, Room 1880, MSC4415, Bethesda, MD 20892, USA
    Eur J Neurosci 17:649-60. 2003
    ..These and other recent findings suggest the need for a revision of prevailing views regarding the neural organization of perception and memory...
  6. ncbi request reprint Interaction of ventral and orbital prefrontal cortex with inferotemporal cortex in conditional visuomotor learning
    Timothy J Bussey
    Laboratory of Neuropsychology, National Institute of Mental Health, Bethesda, Maryland 20892 4415, USA
    Behav Neurosci 116:703-15. 2002
    ..In addition to those associations, which might be considered lower order rules for choosing a response, frontotemporal interaction also appears to be important for higher order rules, such as those involved in the matching task...
  7. ncbi request reprint Perirhinal cortex resolves feature ambiguity in complex visual discriminations
    Timothy J Bussey
    Section on the Neurobiology of Learning and Memory, Laboratory of Neuropsychology, National Institute of Mental Health, Convent Drive, Building 49, Room 1880, MSC4415, Bethesda, MD 20892, USA
    Eur J Neurosci 15:365-74. 2002
    ..These results confirm the predictions of the PMFC model, and force a reconsideration of prevailing views regarding perirhinal cortex function...
  8. ncbi request reprint The organization of visual object representations: a connectionist model of effects of lesions in perirhinal cortex
    Timothy J Bussey
    Section on the Neurobiology of Learning and Memory, Laboratory of Neuropsychology, National Institute of Mental Health, Bethesda, MD 20892, USA
    Eur J Neurosci 15:355-64. 2002
    ....
  9. pmc The touchscreen cognitive testing method for rodents: how to get the best out of your rat
    Timothy J Bussey
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    Learn Mem 15:516-23. 2008
    ..Taken together, these experiments served to optimize the touchscreen method and have demonstrated its usefulness as a high-throughput method for the cognitive testing of rodents...
  10. ncbi request reprint Object memory and perception in the medial temporal lobe: an alternative approach
    Timothy J Bussey
    Dept of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB1 3EB, UK
    Curr Opin Neurobiol 15:730-7. 2005
    ..We propose an alternative approach to understanding the functions of these brain regions in terms of what computations they perform, and what representations they contain...
  11. ncbi request reprint Perirhinal cortex and place-object conditional learning in the rat
    T J Bussey
    School of Psychology, Cardiff University, United Kingdom
    Behav Neurosci 115:776-85. 2001
    ..The results suggest that, although the perirhinal cortex and hippocampus can be functionally dissociated, their normal mode of operation includes the integration of object and spatial information...
  12. ncbi request reprint Distinct patterns of behavioural impairments resulting from fornix transection or neurotoxic lesions of the perirhinal and postrhinal cortices in the rat
    T J Bussey
    School of Psychology, Cardiff University, CF1O 3YG, Cardiff, UK
    Behav Brain Res 111:187-202. 2000
    ..It is suggested that the perirhinal/postrhinal cortex, rather than being specialised for a particular type of associative learning, is important for processing complex visual stimuli...
  13. ncbi request reprint Intact negative patterning in rats with fornix or combined perirhinal and postrhinal cortex lesions
    T J Bussey
    Laboratory of Neuropsychology, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Exp Brain Res 134:506-19. 2000
    ....
  14. doi request reprint Hippocampal lesions in rats impair learning and memory for locations on a touch-sensitive computer screen: the "ASAT" task
    J C Talpos
    Department of Experimental Psychology, University of Cambridge, UK
    Behav Brain Res 192:216-25. 2008
    ..When combined with previously developed non-spatial cognitive tests that can also be run in the touch-screen apparatus, the result is a powerful cognitive test battery for the rodent...
  15. ncbi request reprint Hippocampal lesions that abolish spatial maze performance spare object recognition memory at delays of up to 48 hours
    S E Forwood
    Department of Experimental Psychology, University of Cambridge, Cambridge, United Kingdom
    Hippocampus 15:347-55. 2005
    ..These rats were also tested on a spatial nonmatching-to-place task. Spatial memory performance was abolished following hippocampal lesions, whereas performance on the recognition memory task was intact at all delays tested...
  16. doi request reprint A novel touchscreen-automated paired-associate learning (PAL) task sensitive to pharmacological manipulation of the hippocampus: a translational rodent model of cognitive impairments in neurodegenerative disease
    J C Talpos
    Department of Experimental Psychology, University of Cambridge, Cambridge, UK
    Psychopharmacology (Berl) 205:157-68. 2009
    ..Schizophrenic patients are also impaired on this same task. An automated rodent model of PAL would be extremely beneficial in further research into Alzheimer's disease and schizophrenia...
  17. doi request reprint Heightened susceptibility to interference in an animal model of amnesia: impairment in encoding, storage, retrieval--or all three?
    Susan J Bartko
    Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
    Neuropsychologia 48:2987-97. 2010
    ....
  18. ncbi request reprint Role of the hippocampal system in associative learning beyond the spatial domain
    P J Brasted
    Laboratory of Systems Neuroscience, National Institute of Mental Health, Bethesda, MD 20892 4401, USA
    Brain 126:1202-23. 2003
    ....
  19. pmc Trial-unique, delayed nonmatching-to-location (TUNL): a novel, highly hippocampus-dependent automated touchscreen test of location memory and pattern separation
    J C Talpos
    Department of Experimental Psychology, Downing Street, Cambridge CB2 3EB, UK
    Neurobiol Learn Mem 94:341-52. 2010
    ..Performance-enhancing mediating behaviors during the task were found to be minimal. Thus, the TUNL task has the potential to serve as a powerful tool for the study of the neurobiology of learning and memory...
  20. doi request reprint Paradoxical false memory for objects after brain damage
    Stephanie M McTighe
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, UK
    Science 330:1408-10. 2010
    ..This impairment could be rescued with the use of a visual-restriction procedure that reduces interference. Such a pattern of data can be explained in terms of a recent representational-hierarchical view of cognition...
  21. ncbi request reprint Visual perception and memory: a new view of medial temporal lobe function in primates and rodents
    Elisabeth A Murray
    Section on the Neurobiology of Learning and Memory, Laboratory of Neuropsychology, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    Annu Rev Neurosci 30:99-122. 2007
    ..In both primates and rodents, the hippocampus contributes to the memory and perception of places and paths, whereas the perirhinal cortex does so for objects and the contents of scenes...
  22. doi request reprint Muscimol, AP5, or scopolamine infused into perirhinal cortex impairs two-choice visual discrimination learning in rats
    Boyer D Winters
    Department of Experimental Psychology, University of Cambridge, Downing St, Cambridge CB2 3EB, UK
    Neurobiol Learn Mem 93:221-8. 2010
    ..The involvement of PRh in both types of tasks may be related to its role in complex visual stimulus representation...
  23. ncbi request reprint The parahippocampal region and object identification
    E A Murray
    Laboratory of Neuropsychology, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    Ann N Y Acad Sci 911:166-74. 2000
    ....
  24. ncbi request reprint Conditional motor learning in the nonspatial domain: effects of errorless learning and the contribution of the fornix to one-trial learning
    Peter J Brasted
    Laboratory of Systems Neuroscience, National Institute of Mental Health, Bethesda, MD 20892 4401, USA
    Behav Neurosci 119:662-76. 2005
    ..In addition, the authors examined the effect of errorless learning and found, in control monkeys, that errors made prior to the 1st correct response retarded 1-trial learning...
  25. ncbi request reprint Discrimination of computer-graphic stimuli by mice: a method for the behavioral characterization of transgenic and gene-knockout models
    T J Bussey
    Department of Experimental Psychology, University of Cambridge, England
    Behav Neurosci 115:957-60. 2001
    ..Furthermore, the method seems particularly well suited to the comprehensive behavioral assessment of transgenic and gene-knockout models...
  26. ncbi request reprint Effects of selective thalamic and prelimbic cortex lesions on two types of visual discrimination and reversal learning
    Y Chudasama
    School of Psychology, Cardiff University, PO Box 901, Cardiff, Wales, CF10 3YG, UK
    Eur J Neurosci 14:1009-20. 2001
    ..Furthermore, they show that the functions of this thalamic nucleus can be dissociated from those of the anterior thalamus and the prelimbic cortex...
  27. ncbi request reprint Role of prefrontal cortex in a network for arbitrary visuomotor mapping
    E A Murray
    Laboratory of Neuropsychology, National Institute of Mental Health, Bethesda, MD 20892, USA
    Exp Brain Res 133:114-29. 2000
    ..However, in accord with several models, it operates mainly in the intermediate term, pending the consolidation of the relevant information in those neocortical-BG networks...
  28. doi request reprint Spontaneous object recognition and its relevance to schizophrenia: a review of findings from pharmacological, genetic, lesion and developmental rodent models
    L Lyon
    Department of Experimental Psychology, University of Cambridge, Downing St, Cambridge, CB2 3EB, UK
    Psychopharmacology (Berl) 220:647-72. 2012
    ..The opportunity for rapid data collection has made SOR a popular choice in studies that explore cognitive impairment in rodent models of schizophrenia, and that test the efficacy of drugs intended to reverse these deficits...
  29. pmc Scopolamine infused into perirhinal cortex improves object recognition memory by blocking the acquisition of interfering object information
    Boyer D Winters
    Department of Experimental Psychology, University of Cambridge, Cambridge, United Kingdom
    Learn Mem 14:590-6. 2007
    ..This finding provides further, strong evidence that acetylcholine is important for the acquisition of object information in PRh...
  30. ncbi request reprint Rats spontaneously discriminate purely visual, two-dimensional stimuli in tests of recognition memory and perceptual oddity
    Suzanna E Forwood
    Department of Experimental Psychology, University of Cambridge, Cambridge, United Kingdom
    Behav Neurosci 121:1032-42. 2007
    ..These 2 tasks are quick to administer, involve no fearful learning associations, and require a simple apparatus. They may be particularly useful for high-throughput pharmacological or genetic screening using rodent models...
  31. pmc Perirhinal cortex resolves feature ambiguity in configural object recognition and perceptual oddity tasks
    Susan J Bartko
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    Learn Mem 14:821-32. 2007
    ..These findings support the idea that PRh contains conjunctive representations for the resolution of feature ambiguity and that these representations underlie a dual role for PRh in memory and perception...
  32. ncbi request reprint Can animals recall the past and plan for the future?
    Nicola S Clayton
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    Nat Rev Neurosci 4:685-91. 2003
    ..Moreover, these birds can adjust their caching behaviour in anticipation of future needs. We suggest that some animals have elements of both episodic-like memory and future planning...
  33. ncbi request reprint Fornix transection impairs conditional visuomotor learning in tasks involving nonspatially differentiated responses
    Peter J Brasted
    Laboratory of Systems Neuroscience, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    J Neurophysiol 87:631-3. 2002
    ..These findings challenge the view that the hippocampal system participates in associative learning only when spatial information is relevant to either the stimulus or the response...
  34. pmc Impaired fear extinction learning and cortico-amygdala circuit abnormalities in a common genetic mouse strain
    Kathryn Hefner
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcoholism and Alcohol Abuse, National Institutes of Health, Rockville, Maryland 20852, USA
    J Neurosci 28:8074-85. 2008
    ..This common inbred strain provides a novel model for studying impaired fear extinction in anxiety disorders...
  35. doi request reprint A new touchscreen test of pattern separation: effect of hippocampal lesions
    Stephanie M McTighe
    Department of Experimental Psychology, University of Cambridge, Cambridge, UK
    Neuroreport 20:881-5. 2009
    ..This test provides an automated test of pattern separation, which adds to an expanding battery of cognitive tests that can be carried out using the touchscreen testing method...
  36. ncbi request reprint No effect of hippocampal lesions on perirhinal cortex-dependent feature-ambiguous visual discriminations
    Lisa M Saksida
    Department of Experimental Psychology, University of Cambridge, Cambridge, UK
    Hippocampus 16:421-30. 2006
    ..The findings support the perceptual-mnemonic/feature conjunction model of perirhinal cortex function, and provide further evidence for heterogeneity of function within the putative medial temporal lobe memory system...
  37. doi request reprint The representational-hierarchical view of amnesia: translation from animal to human
    Lisa M Saksida
    Department of Experimental Psychology, University of Cambridge, Cambridge, UK
    Neuropsychologia 48:2370-84. 2010
    ..Finally, we provide evidence from animal and human studies that even the hippocampus-almost universally regarded as a module for memory-may be better understood within the representational-hierarchical paradigm...
  38. ncbi request reprint Double dissociation between the effects of peri-postrhinal cortex and hippocampal lesions on tests of object recognition and spatial memory: heterogeneity of function within the temporal lobe
    Boyer D Winters
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 24:5901-8. 2004
    ..These results provide strong evidence in favor of heterogeneity and independence of function within the temporal lobe...
  39. ncbi request reprint Transient inactivation of perirhinal cortex disrupts encoding, retrieval, and consolidation of object recognition memory
    Boyer D Winters
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 25:52-61. 2005
    ....
  40. ncbi request reprint Specialization in the medial temporal lobe for processing of objects and scenes
    Andy C H Lee
    MRC Cognition and Brain Sciences Unit, 15 Chaucer Road, Cambridge, UK
    Hippocampus 15:782-97. 2005
    ..These observations provide compelling evidence that the human hippocampus and perirhinal cortex are critical to processes beyond long-term declarative memory and may subserve spatial and object perception, respectively...
  41. ncbi request reprint The perceptual-mnemonic/feature conjunction model of perirhinal cortex function
    Timothy J Bussey
    Department of Experimental Psychology, University of Cambridge, UK
    Q J Exp Psychol B 58:269-82. 2005
    ....
  42. ncbi request reprint Functional specialization in the human medial temporal lobe
    Morgan D Barense
    Medical Research Council Cognition and Brain Sciences Unit, Cambridge CB2 2EF, United Kingdom
    J Neurosci 25:10239-46. 2005
    ..These findings resolve contradictions between published studies in humans and animals and introduce a new way of characterizing the impairments that arise after damage to the MTL...
  43. ncbi request reprint Removal of cholinergic input to perirhinal cortex disrupts object recognition but not spatial working memory in the rat
    Boyer D Winters
    Department of Experimental Psychology, University of Cambridge, Downing St, Cambridge CB2 3EB, UK
    Eur J Neurosci 21:2263-70. 2005
    ....
  44. ncbi request reprint Impairment and facilitation of transverse patterning after lesions of the perirhinal cortex and hippocampus, respectively
    Lisa M Saksida
    Department of Experimental Psychology, University of Cambridge, Cambridge, UK
    Cereb Cortex 17:108-15. 2007
    ..These results are, however, compatible with a view that perirhinal cortex, and not the hippocampus, contains complex configural representations of visual stimuli critical to the solution of the transverse-patterning task...
  45. ncbi request reprint Glutamate receptors in perirhinal cortex mediate encoding, retrieval, and consolidation of object recognition memory
    Boyer D Winters
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 25:4243-51. 2005
    ....
  46. doi request reprint Object recognition memory: neurobiological mechanisms of encoding, consolidation and retrieval
    Boyer D Winters
    Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
    Neurosci Biobehav Rev 32:1055-70. 2008
    ..Recent studies in rodents have begun to indicate the remarkable complexity of the neural substrates underlying this seemingly simple aspect of declarative memory...
  47. ncbi request reprint Perceptual functions of perirhinal cortex in rats: zero-delay object recognition and simultaneous oddity discriminations
    Susan J Bartko
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 27:2548-59. 2007
    ..These findings provide support for the idea that PRh in the rat is important for the perceptual processing of complex objects, in addition to its well established role in memory...
  48. ncbi request reprint Abnormal categorization and perceptual learning in patients with hippocampal damage
    Kim S Graham
    Medical Research Council Cognition and Brain Sciences Unit, Cambridge CB2 2EF, United Kingdom
    J Neurosci 26:7547-54. 2006
    ....
  49. ncbi request reprint Why does brain damage impair memory? A connectionist model of object recognition memory in perirhinal cortex
    Rosemary A Cowell
    Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, United Kingdom
    J Neurosci 26:12186-97. 2006
    ....
  50. ncbi request reprint Paradoxical facilitation of object recognition memory after infusion of scopolamine into perirhinal cortex: implications for cholinergic system function
    Boyer D Winters
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 26:9520-9. 2006
    ..Rather, the cholinergic input to the perirhinal cortex may facilitate acquisition by enhancing the cortical processing of incoming stimulus information...
  51. ncbi request reprint Consolidation and the medial temporal lobe revisited: methodological considerations
    E A Murray
    Laboratory of Neuropsychology, National Institute of Mental Health, Bethesda, Maryland 20892 4415, USA
    Hippocampus 11:1-7. 2001
    ....
  52. pmc Assessment of glutamate transporter GLAST (EAAT1)-deficient mice for phenotypes relevant to the negative and executive/cognitive symptoms of schizophrenia
    Rose Marie Karlsson
    Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, NIH, 10 Center Drive, 10 Room 1E 5330, Bethesda, MD 20892, USA
    Neuropsychopharmacology 34:1578-89. 2009
    ..These findings demonstrate that gene deletion of GLAST produces select phenotypic abnormalities related to the negative and cognitive symptoms of schizophrenia...
  53. pmc Impaired discrimination learning in mice lacking the NMDA receptor NR2A subunit
    Jonathan L Brigman
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute on Alcoholism and Alcohol Abuse, National Institutes of Health, Rockville, Maryland 20852, USA
    Learn Mem 15:50-4. 2008
    ..The present findings demonstrate a significant and selective deficit in discrimination learning following loss of NR2A...
  54. ncbi request reprint Role of the anterior cingulate cortex in the control over behavior by Pavlovian conditioned stimuli in rats
    Rudolf N Cardinal
    Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, United Kingdom
    Behav Neurosci 117:566-87. 2003
    ..It is suggested that the ACC is not critical for stimulus-reward learning per se, but is required to discriminate multiple stimuli on the basis of their association with reward...
  55. ncbi request reprint Discrimination of multidimensional visual stimuli by mice: intra- and extradimensional shifts
    Jonathan L Brigman
    Department of Psychology, George Washington University, Washington, DC 20052, USA
    Behav Neurosci 119:839-42. 2005
    ..The fact that mice can be tested with stimuli and task sequences similar to those used with primates suggests that this method can be used to directly compare higher cognitive functions in diverse species...
  56. ncbi request reprint Genetic and dopaminergic modulation of reversal learning in a touchscreen-based operant procedure for mice
    Alicia Izquierdo
    Section on Behavioral Science and Genetics, Laboratory for Integrative Neuroscience, National Institute of Alcohol Abuse and Alcoholism, NIH, Rockville, USA
    Behav Brain Res 171:181-8. 2006
    ..When combined with emerging molecular techniques uniquely suited to this species such as genetic engineering and RNA modification this paradigm could provide a powerful new tool for behavioral neuroscience...
  57. ncbi request reprint Measuring cognitive deficits in disabled mice using an automated interactive touchscreen system
    A Jennifer Morton
    Nat Methods 3:767. 2006
  58. ncbi request reprint Perirhinal cortex and feature-ambiguous discriminations
    Timothy J Bussey
    Learn Mem 13:103-5; author reply 106-7. 2006