F Buss

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. pmc Myosin VI is required for targeted membrane transport during cytokinesis
    Susan D Arden
    Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 2XY, United Kingdom
    Mol Biol Cell 18:4750-61. 2007
  2. pmc Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis
    Daniela A Sahlender
    Cambridge Institute for Medical Research, University of Cambridge, England, UK
    J Cell Biol 169:285-95. 2005
  3. pmc Myosin VI is required for sorting of AP-1B-dependent cargo to the basolateral domain in polarized MDCK cells
    Josephine Sui Yan Au
    Medical Research Council Laboratory of Molecular Biology, Cambridge CB2 2QH, England, UK
    J Cell Biol 177:103-14. 2007
  4. pmc Overexpression of myosin VI in prostate cancer cells enhances PSA and VEGF secretion, but has no effect on endocytosis
    C Puri
    Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Cambridge, UK
    Oncogene 29:188-200. 2010
  5. pmc Myosin VI and optineurin are required for polarized EGFR delivery and directed migration
    Margarita V Chibalina
    Cambridge Institute for Medical Research, Department of Clinical Biochemistry, University of Cambridge, Wellcome Trust MRC Building, Hills Road, Cambridge, CB2 0XY, UK
    Traffic 11:1290-303. 2010
  6. pmc Dynamic exchange of myosin VI on endocytic structures
    Lisa M Bond
    Laboratory of Molecular Physiology, NHLBI, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 287:38637-46. 2012
  7. pmc Molecular roles of Myo1c function in lipid raft exocytosis
    Hemma Brandstaetter
    Cambridge Institute for Medical Research University of Cambridge Cambridge, UK
    Commun Integr Biol 5:508-10. 2012
  8. pmc Functional roles for myosin 1c in cellular signaling pathways
    Lisa M Bond
    Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Hills Road, Cambridge, CB2 0XY, United Kingdom
    Cell Signal 25:229-35. 2013
  9. pmc How are the cellular functions of myosin VI regulated within the cell?
    Folma Buss
    Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Hills Road, Cambridge CB2 2XY, UK
    Biochem Biophys Res Commun 369:165-75. 2008
  10. ncbi request reprint Myosin VI, a new force in clathrin mediated endocytosis
    F Buss
    Department of Clinical Biochemistry, University of Cambridge, UK
    FEBS Lett 508:295-9. 2001

Collaborators

Detail Information

Publications27

  1. pmc Myosin VI is required for targeted membrane transport during cytokinesis
    Susan D Arden
    Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 2XY, United Kingdom
    Mol Biol Cell 18:4750-61. 2007
    ..Our results suggest that myosin VI has novel functions in mitosis and that it plays an essential role in targeted membrane transport during cytokinesis...
  2. pmc Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis
    Daniela A Sahlender
    Cambridge Institute for Medical Research, University of Cambridge, England, UK
    J Cell Biol 169:285-95. 2005
    ..These results show that optineurin links myosin VI to the Golgi complex and plays a central role in Golgi ribbon formation and exocytosis...
  3. pmc Myosin VI is required for sorting of AP-1B-dependent cargo to the basolateral domain in polarized MDCK cells
    Josephine Sui Yan Au
    Medical Research Council Laboratory of Molecular Biology, Cambridge CB2 2QH, England, UK
    J Cell Biol 177:103-14. 2007
    ..Our results suggest that myosin VI is a crucial component in the AP-1B-dependent biosynthetic sorting pathway to the basolateral surface in polarized epithelial cells...
  4. pmc Overexpression of myosin VI in prostate cancer cells enhances PSA and VEGF secretion, but has no effect on endocytosis
    C Puri
    Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Cambridge, UK
    Oncogene 29:188-200. 2010
    ..Our results suggest that in prostate cancer cells, myosin VI regulates protein secretion, but the overexpression of myosin VI has no major impact on clathrin-mediated endocytosis...
  5. pmc Myosin VI and optineurin are required for polarized EGFR delivery and directed migration
    Margarita V Chibalina
    Cambridge Institute for Medical Research, Department of Clinical Biochemistry, University of Cambridge, Wellcome Trust MRC Building, Hills Road, Cambridge, CB2 0XY, UK
    Traffic 11:1290-303. 2010
    ..In summary, we identified a specific role for myosin VI and optineurin in directionally persistent cell migration, which involves the polarized delivery of vesicles containing EGFR into the leading edge of the cell...
  6. pmc Dynamic exchange of myosin VI on endocytic structures
    Lisa M Bond
    Laboratory of Molecular Physiology, NHLBI, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 287:38637-46. 2012
    ..Taken together, these FRAP results offer insight into both the basic turnover dynamics and the monomer/dimer nature of myosin VI...
  7. pmc Molecular roles of Myo1c function in lipid raft exocytosis
    Hemma Brandstaetter
    Cambridge Institute for Medical Research University of Cambridge Cambridge, UK
    Commun Integr Biol 5:508-10. 2012
    ..Here we present a model suggesting Myo1c's possible molecular functions in lipid raft recycling and discuss its wider implications for important cellular functions...
  8. pmc Functional roles for myosin 1c in cellular signaling pathways
    Lisa M Bond
    Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Hills Road, Cambridge, CB2 0XY, United Kingdom
    Cell Signal 25:229-35. 2013
    ..This review provides an overview of the functional involvement of myosin 1c in cellular signaling and discusses the possible potential for myosin 1c as a target for drug-based treatments for human diseases...
  9. pmc How are the cellular functions of myosin VI regulated within the cell?
    Folma Buss
    Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Hills Road, Cambridge CB2 2XY, UK
    Biochem Biophys Res Commun 369:165-75. 2008
    ..Understanding the functions of myosin VI within the cell and how it is regulated is now of utmost importance given the recent observations that it is associated with a number of human disorders such as deafness and cancers...
  10. ncbi request reprint Myosin VI, a new force in clathrin mediated endocytosis
    F Buss
    Department of Clinical Biochemistry, University of Cambridge, UK
    FEBS Lett 508:295-9. 2001
    ..The possible role(s) of myosin VI in the sequential steps involved in receptor mediated endocytosis are discussed...
  11. pmc Myosin VI isoform localized to clathrin-coated vesicles with a role in clathrin-mediated endocytosis
    F Buss
    Department of Clinical Biochemistry and Wellcome Trust Centre for the Study of Molecular Mechanisms in Disease, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke s Hospital, Cambridge CB2 2XY, UK
    EMBO J 20:3676-84. 2001
    ..Myosin VI is the first motor protein to be identified associated with clathrin-coated pits/vesicles and shown to modulate clathrin-mediated endocytosis...
  12. ncbi request reprint Myosin VI: cellular functions and motor properties
    Folma Buss
    Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 2XY, United Kingdom
    Annu Rev Cell Dev Biol 20:649-76. 2004
    ....
  13. pmc The localization of myosin VI at the golgi complex and leading edge of fibroblasts and its phosphorylation and recruitment into membrane ruffles of A431 cells after growth factor stimulation
    F Buss
    Department of Clinical Biochemistry, University of Cambridge, Addenbrooke s Hospital, Cambridge, CB2 2QR, United Kingdom
    J Cell Biol 143:1535-45. 1998
    ..These results strongly support a role for myosin VI in membrane traffic on secretory and endocytic pathways...
  14. ncbi request reprint Myosin VI, an actin motor for membrane traffic and cell migration
    Folma Buss
    Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Hills Road, Cambridge CB2 2XY, UK
    Traffic 3:851-8. 2002
    ..These diverse functions of myosin VI are mediated by interaction with a range of different binding partners...
  15. ncbi request reprint Myosin VI: a multifunctional motor
    I Lister
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Biochem Soc Trans 32:685-8. 2004
    ..Using an optical tweezers force transducer, we showed that monomeric myosin VI is a non-processive motor with a large working stroke of 18 nm. Potential roles for myosin VI in cells are discussed...
  16. ncbi request reprint Localization of myosin Va is dependent on the cytoskeletal organization in the cell
    C Lionne
    Medical Research Centre, Laboratory of Molecular Biology, Structural Studies Division, Cambridge, UK
    Biochem Cell Biol 79:93-106. 2001
    ..In polarized epithelial cells (WIF-B), where the microtubule-organizing region is close to the actin-rich apical surface, one single pool of myosin V, sensitive to the integrity of both microtubules and actin filaments, was observed...
  17. pmc Myosin VI and its interacting protein LMTK2 regulate tubule formation and transport to the endocytic recycling compartment
    Margarita V Chibalina
    Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Hills Road, Cambridge, CB2 2XY, UK
    J Cell Sci 120:4278-88. 2007
    ....
  18. pmc Myosin VI: cellular functions and motor properties
    Rhys Roberts
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Philos Trans R Soc Lond B Biol Sci 359:1931-44. 2004
    ..Whether monomer and/or dimer forms of myosin VI exist in cells and their possible functions will be discussed...
  19. pmc T6BP and NDP52 are myosin VI binding partners with potential roles in cytokine signalling and cell adhesion
    Brooke Morriswood
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK
    J Cell Sci 120:2574-85. 2007
    ..Thus myosin VI-T6BP interactions may link membrane trafficking pathways with cell adhesion and cytokine-dependent cell signalling...
  20. pmc Mistargeting of SH3TC2 away from the recycling endosome causes Charcot-Marie-Tooth disease type 4C
    Rhys C Roberts
    Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK
    Hum Mol Genet 19:1009-18. 2010
    ..Our data therefore implicate mistargeting of SH3TC2 away from the recycling endosome as the fundamental molecular defect that leads to CMT4C...
  21. pmc Potential roles of myosin VI in cell motility
    Margarita V Chibalina
    Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Hills Road, Cambridge, UK
    Biochem Soc Trans 37:966-70. 2009
    ..Myosins exist as a large superfamily of diverse ATP-dependent motors, and in the present review, we focus on the unique minus-end-directed myosin VI, briefly discussing its potential functions in cell motility...
  22. pmc Macromolecular interactions in the nucleoporin p62 complex of rat nuclear pores: binding of nucleoporin p54 to the rod domain of p62
    F Buss
    Medical Research Council Laboratory of Molecular Biology, Cambridge, England
    J Cell Biol 128:251-61. 1995
    ..This model is consistent with data that indicate that the analogous coiled-coil region of yeast nucleoporin NSP1 may function in a similar way...
  23. pmc Myosin VI targeting to clathrin-coated structures and dimerization is mediated by binding to Disabled-2 and PtdIns(4,5)P2
    Giulietta Spudich
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Nat Cell Biol 9:176-83. 2007
    ..In vivo targeting and recruitment of myosin VI to clathrin-coated structures (CCSs) at the plasma membrane is mediated by Dab2 and PtdIns(4,5)P2 binding...
  24. pmc Rab8-optineurin-myosin VI: analysis of interactions and functions in the secretory pathway
    Margarita V Chibalina
    Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom
    Methods Enzymol 438:11-24. 2008
    ..We describe a secretion assay that was used in combination with RNA interference technology to analyze the function of myosin VI, optineurin, and Rab8 in exocytic membrane trafficking pathways...
  25. pmc A monomeric myosin VI with a large working stroke
    Ida Lister
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, UK
    EMBO J 23:1729-38. 2004
    ..A possible model to explain the large working stroke of myosin VI is presented...
  26. pmc Loss of myosin VI reduces secretion and the size of the Golgi in fibroblasts from Snell's waltzer mice
    Claire L Warner
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    EMBO J 22:569-79. 2003
    ..Rescue experiments showed that fully functional myosin VI was able to restore Golgi complex morphology and protein secretion in Snell's waltzer cells to the same level as that observed in wild-type cells...
  27. ncbi request reprint Myosin VI binds to and localises with Dab2, potentially linking receptor-mediated endocytosis and the actin cytoskeleton
    Shelli M Morris
    Fred Hutchinson Cancer Research Center, Division of Basic Sciences, 1100 Fairview Avenue North, Seattle, WA 98109 1024, USA
    Traffic 3:331-41. 2002
    ..These results suggest that the myosin VI-Dab2 interaction may be one link between the actin cytoskeleton and receptors undergoing endocytosis...