F Buss

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi Myosin VI is required for targeted membrane transport during cytokinesis
    Susan D Arden
    Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 2XY, United Kingdom
    Mol Biol Cell 18:4750-61. 2007
  2. ncbi How are the cellular functions of myosin VI regulated within the cell?
    Folma Buss
    Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Hills Road, Cambridge CB2 2XY, UK
    Biochem Biophys Res Commun 369:165-75. 2008
  3. ncbi Myosin VI: cellular functions and motor properties
    Folma Buss
    Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 2XY, United Kingdom
    Annu Rev Cell Dev Biol 20:649-76. 2004
  4. ncbi The localization of myosin VI at the golgi complex and leading edge of fibroblasts and its phosphorylation and recruitment into membrane ruffles of A431 cells after growth factor stimulation
    F Buss
    Department of Clinical Biochemistry, University of Cambridge, Addenbrooke s Hospital, Cambridge, CB2 2QR, United Kingdom
    J Cell Biol 143:1535-45. 1998
  5. ncbi Myosin VI, an actin motor for membrane traffic and cell migration
    Folma Buss
    Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Hills Road, Cambridge CB2 2XY, UK
    Traffic 3:851-8. 2002
  6. ncbi Myosin VI, a new force in clathrin mediated endocytosis
    F Buss
    Department of Clinical Biochemistry, University of Cambridge, UK
    FEBS Lett 508:295-9. 2001
  7. ncbi Myosin VI isoform localized to clathrin-coated vesicles with a role in clathrin-mediated endocytosis
    F Buss
    Department of Clinical Biochemistry and Wellcome Trust Centre for the Study of Molecular Mechanisms in Disease, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke s Hospital, Cambridge CB2 2XY, UK
    EMBO J 20:3676-84. 2001
  8. ncbi Overexpression of myosin VI in prostate cancer cells enhances PSA and VEGF secretion, but has no effect on endocytosis
    C Puri
    Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Cambridge, UK
    Oncogene 29:188-200. 2010
  9. ncbi Localization of myosin Va is dependent on the cytoskeletal organization in the cell
    C Lionne
    Medical Research Centre, Laboratory of Molecular Biology, Structural Studies Division, Cambridge, UK
    Biochem Cell Biol 79:93-106. 2001
  10. ncbi Myosin VI: a multifunctional motor
    I Lister
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Biochem Soc Trans 32:685-8. 2004

Collaborators

Detail Information

Publications22

  1. ncbi Myosin VI is required for targeted membrane transport during cytokinesis
    Susan D Arden
    Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 2XY, United Kingdom
    Mol Biol Cell 18:4750-61. 2007
    ..Our results suggest that myosin VI has novel functions in mitosis and that it plays an essential role in targeted membrane transport during cytokinesis...
  2. ncbi How are the cellular functions of myosin VI regulated within the cell?
    Folma Buss
    Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Hills Road, Cambridge CB2 2XY, UK
    Biochem Biophys Res Commun 369:165-75. 2008
    ..Understanding the functions of myosin VI within the cell and how it is regulated is now of utmost importance given the recent observations that it is associated with a number of human disorders such as deafness and cancers...
  3. ncbi Myosin VI: cellular functions and motor properties
    Folma Buss
    Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 2XY, United Kingdom
    Annu Rev Cell Dev Biol 20:649-76. 2004
    ....
  4. ncbi The localization of myosin VI at the golgi complex and leading edge of fibroblasts and its phosphorylation and recruitment into membrane ruffles of A431 cells after growth factor stimulation
    F Buss
    Department of Clinical Biochemistry, University of Cambridge, Addenbrooke s Hospital, Cambridge, CB2 2QR, United Kingdom
    J Cell Biol 143:1535-45. 1998
    ..These results strongly support a role for myosin VI in membrane traffic on secretory and endocytic pathways...
  5. ncbi Myosin VI, an actin motor for membrane traffic and cell migration
    Folma Buss
    Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Hills Road, Cambridge CB2 2XY, UK
    Traffic 3:851-8. 2002
    ..These diverse functions of myosin VI are mediated by interaction with a range of different binding partners...
  6. ncbi Myosin VI, a new force in clathrin mediated endocytosis
    F Buss
    Department of Clinical Biochemistry, University of Cambridge, UK
    FEBS Lett 508:295-9. 2001
    ..The possible role(s) of myosin VI in the sequential steps involved in receptor mediated endocytosis are discussed...
  7. ncbi Myosin VI isoform localized to clathrin-coated vesicles with a role in clathrin-mediated endocytosis
    F Buss
    Department of Clinical Biochemistry and Wellcome Trust Centre for the Study of Molecular Mechanisms in Disease, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke s Hospital, Cambridge CB2 2XY, UK
    EMBO J 20:3676-84. 2001
    ..Myosin VI is the first motor protein to be identified associated with clathrin-coated pits/vesicles and shown to modulate clathrin-mediated endocytosis...
  8. ncbi Overexpression of myosin VI in prostate cancer cells enhances PSA and VEGF secretion, but has no effect on endocytosis
    C Puri
    Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Cambridge, UK
    Oncogene 29:188-200. 2010
    ..Our results suggest that in prostate cancer cells, myosin VI regulates protein secretion, but the overexpression of myosin VI has no major impact on clathrin-mediated endocytosis...
  9. ncbi Localization of myosin Va is dependent on the cytoskeletal organization in the cell
    C Lionne
    Medical Research Centre, Laboratory of Molecular Biology, Structural Studies Division, Cambridge, UK
    Biochem Cell Biol 79:93-106. 2001
    ..In polarized epithelial cells (WIF-B), where the microtubule-organizing region is close to the actin-rich apical surface, one single pool of myosin V, sensitive to the integrity of both microtubules and actin filaments, was observed...
  10. ncbi Myosin VI: a multifunctional motor
    I Lister
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Biochem Soc Trans 32:685-8. 2004
    ..Using an optical tweezers force transducer, we showed that monomeric myosin VI is a non-processive motor with a large working stroke of 18 nm. Potential roles for myosin VI in cells are discussed...
  11. ncbi Myosin VI and its interacting protein LMTK2 regulate tubule formation and transport to the endocytic recycling compartment
    Margarita V Chibalina
    Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Hills Road, Cambridge, CB2 2XY, UK
    J Cell Sci 120:4278-88. 2007
    ....
  12. ncbi Myosin VI: cellular functions and motor properties
    Rhys Roberts
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Philos Trans R Soc Lond B Biol Sci 359:1931-44. 2004
    ..Whether monomer and/or dimer forms of myosin VI exist in cells and their possible functions will be discussed...
  13. ncbi T6BP and NDP52 are myosin VI binding partners with potential roles in cytokine signalling and cell adhesion
    Brooke Morriswood
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK
    J Cell Sci 120:2574-85. 2007
    ..Thus myosin VI-T6BP interactions may link membrane trafficking pathways with cell adhesion and cytokine-dependent cell signalling...
  14. ncbi Potential roles of myosin VI in cell motility
    Margarita V Chibalina
    Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Hills Road, Cambridge, UK
    Biochem Soc Trans 37:966-70. 2009
    ..Myosins exist as a large superfamily of diverse ATP-dependent motors, and in the present review, we focus on the unique minus-end-directed myosin VI, briefly discussing its potential functions in cell motility...
  15. ncbi Mistargeting of SH3TC2 away from the recycling endosome causes Charcot-Marie-Tooth disease type 4C
    Rhys C Roberts
    Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK
    Hum Mol Genet 19:1009-18. 2010
    ..Our data therefore implicate mistargeting of SH3TC2 away from the recycling endosome as the fundamental molecular defect that leads to CMT4C...
  16. ncbi Myosin VI targeting to clathrin-coated structures and dimerization is mediated by binding to Disabled-2 and PtdIns(4,5)P2
    Giulietta Spudich
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Nat Cell Biol 9:176-83. 2007
    ..In vivo targeting and recruitment of myosin VI to clathrin-coated structures (CCSs) at the plasma membrane is mediated by Dab2 and PtdIns(4,5)P2 binding...
  17. ncbi Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis
    Daniela A Sahlender
    Cambridge Institute for Medical Research, University of Cambridge, England, UK
    J Cell Biol 169:285-95. 2005
    ..These results show that optineurin links myosin VI to the Golgi complex and plays a central role in Golgi ribbon formation and exocytosis...
  18. ncbi A monomeric myosin VI with a large working stroke
    Ida Lister
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, UK
    EMBO J 23:1729-38. 2004
    ..A possible model to explain the large working stroke of myosin VI is presented...
  19. ncbi Rab8-optineurin-myosin VI: analysis of interactions and functions in the secretory pathway
    Margarita V Chibalina
    Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom
    Methods Enzymol 438:11-24. 2008
    ..We describe a secretion assay that was used in combination with RNA interference technology to analyze the function of myosin VI, optineurin, and Rab8 in exocytic membrane trafficking pathways...
  20. ncbi Loss of myosin VI reduces secretion and the size of the Golgi in fibroblasts from Snell's waltzer mice
    Claire L Warner
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    EMBO J 22:569-79. 2003
    ..Rescue experiments showed that fully functional myosin VI was able to restore Golgi complex morphology and protein secretion in Snell's waltzer cells to the same level as that observed in wild-type cells...
  21. ncbi Myosin VI binds to and localises with Dab2, potentially linking receptor-mediated endocytosis and the actin cytoskeleton
    Shelli M Morris
    Fred Hutchinson Cancer Research Center, Division of Basic Sciences, 1100 Fairview Avenue North, Seattle, WA 98109 1024, USA
    Traffic 3:331-41. 2002
    ..These results suggest that the myosin VI-Dab2 interaction may be one link between the actin cytoskeleton and receptors undergoing endocytosis...
  22. ncbi Myosin VI is required for sorting of AP-1B-dependent cargo to the basolateral domain in polarized MDCK cells
    Josephine Sui Yan Au
    Medical Research Council Laboratory of Molecular Biology, Cambridge CB2 2QH, England, UK
    J Cell Biol 177:103-14. 2007
    ..Our results suggest that myosin VI is a crucial component in the AP-1B-dependent biosynthetic sorting pathway to the basolateral surface in polarized epithelial cells...