Emma J Burton

Summary

Affiliation: University of Newcastle
Country: UK

Publications

  1. doi request reprint Quantitative neurodegenerative pathology does not explain the degree of hippocampal atrophy on MRI in degenerative dementia
    E J Burton
    Institute for Ageing and Health, Newcastle University, UK
    Int J Geriatr Psychiatry 27:1267-74. 2012
  2. doi request reprint Neuropathological correlates of volumetric MRI in autopsy-confirmed Lewy body dementia
    Emma J Burton
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK
    Neurobiol Aging 33:1228-36. 2012
  3. ncbi request reprint Patterns of cerebral atrophy in dementia with Lewy bodies using voxel-based morphometry
    E J Burton
    Institute for Ageing and Health, University of Newcastle upon Tyne, United Kingdom
    Neuroimage 17:618-30. 2002
  4. doi request reprint Medial temporal lobe atrophy on MRI differentiates Alzheimer's disease from dementia with Lewy bodies and vascular cognitive impairment: a prospective study with pathological verification of diagnosis
    E J Burton
    Wolfson Research Centre, Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK
    Brain 132:195-203. 2009
  5. ncbi request reprint Cerebral atrophy in Parkinson's disease with and without dementia: a comparison with Alzheimer's disease, dementia with Lewy bodies and controls
    Emma J Burton
    The Institute for Ageing and Health, University of Newcastle upon Tyne, Newcastle General Hospital, Newcastle, UK
    Brain 127:791-800. 2004
  6. ncbi request reprint Brain atrophy rates in Parkinson's disease with and without dementia using serial magnetic resonance imaging
    Emma J Burton
    Institute for Ageing and Health, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    Mov Disord 20:1571-6. 2005
  7. ncbi request reprint High resolution imaging of the medial temporal lobe in Alzheimer's disease and dementia with Lewy bodies
    Michael J Firbank
    Institute for Ageing and Health, Newcastle University, Newcastle, UK
    J Alzheimers Dis 21:1129-40. 2010
  8. ncbi request reprint Validation of a fully automated hippocampal segmentation method on patients with dementia
    Michael J Firbank
    Institute for Ageing and Health, Newcastle University, Wolfson Research Centre, Westgate Road, Newcastle upon Tyne NE4 6BE, United Kingdom
    Hum Brain Mapp 29:1442-9. 2008
  9. ncbi request reprint Progression of white matter hyperintensities in Alzheimer disease, dementia with lewy bodies, and Parkinson disease dementia: a comparison with normal aging
    Emma J Burton
    Institute for Ageing and Health, Wolfson Research Centre, Newcastle General Hospital, Newcastle upon Tyne, UK
    Am J Geriatr Psychiatry 14:842-9. 2006
  10. doi request reprint Does posterior cortical atrophy on MRI discriminate between Alzheimer's disease, dementia with Lewy bodies, and normal aging?
    James O'Donovan
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    Int Psychogeriatr 25:111-9. 2013

Detail Information

Publications23

  1. doi request reprint Quantitative neurodegenerative pathology does not explain the degree of hippocampal atrophy on MRI in degenerative dementia
    E J Burton
    Institute for Ageing and Health, Newcastle University, UK
    Int J Geriatr Psychiatry 27:1267-74. 2012
    ..The purpose of this study was to investigate the neuropathological substrates underlying in vivo hippocampal atrophy on magnetic resonance imaging (MRI) in autopsy confirmed neurodegenerative dementia cases...
  2. doi request reprint Neuropathological correlates of volumetric MRI in autopsy-confirmed Lewy body dementia
    Emma J Burton
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK
    Neurobiol Aging 33:1228-36. 2012
    ....
  3. ncbi request reprint Patterns of cerebral atrophy in dementia with Lewy bodies using voxel-based morphometry
    E J Burton
    Institute for Ageing and Health, University of Newcastle upon Tyne, United Kingdom
    Neuroimage 17:618-30. 2002
    ..Comparison of dementia groups showed preservation of the medial temporal lobe, hippocampus, and amygdala in DLB relative to AD. Significant gray matter loss was also observed in the thalamus of AD patients compared to DLB...
  4. doi request reprint Medial temporal lobe atrophy on MRI differentiates Alzheimer's disease from dementia with Lewy bodies and vascular cognitive impairment: a prospective study with pathological verification of diagnosis
    E J Burton
    Wolfson Research Centre, Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK
    Brain 132:195-203. 2009
    ..Pathologically, it is more strongly related to tangle rather than plaque or Lewy body pathology in the temporal lobe. It may have utility as a means for stratifying samples in vivo on the basis of putative differences in pathology...
  5. ncbi request reprint Cerebral atrophy in Parkinson's disease with and without dementia: a comparison with Alzheimer's disease, dementia with Lewy bodies and controls
    Emma J Burton
    The Institute for Ageing and Health, University of Newcastle upon Tyne, Newcastle General Hospital, Newcastle, UK
    Brain 127:791-800. 2004
    ..This provides important information about the pattern of cerebral atrophy in Parkinson's disease and PDD...
  6. ncbi request reprint Brain atrophy rates in Parkinson's disease with and without dementia using serial magnetic resonance imaging
    Emma J Burton
    Institute for Ageing and Health, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    Mov Disord 20:1571-6. 2005
    ..Serial MRI may be a useful tool for monitoring disease progression in PDD and further studies should investigate its utility for early diagnosis...
  7. ncbi request reprint High resolution imaging of the medial temporal lobe in Alzheimer's disease and dementia with Lewy bodies
    Michael J Firbank
    Institute for Ageing and Health, Newcastle University, Newcastle, UK
    J Alzheimers Dis 21:1129-40. 2010
    ..Future studies should investigate whether subiculum thickness or the hypointense line could be a diagnostic feature to help discriminate AD from DLB...
  8. ncbi request reprint Validation of a fully automated hippocampal segmentation method on patients with dementia
    Michael J Firbank
    Institute for Ageing and Health, Newcastle University, Wolfson Research Centre, Westgate Road, Newcastle upon Tyne NE4 6BE, United Kingdom
    Hum Brain Mapp 29:1442-9. 2008
    ..Linear regression between manual and automated volume gave V(auto) = V(manual) x 0.83 + 401 ml. The method provides an acceptable automated alternative to manual segmentation which may be of value in large studies...
  9. ncbi request reprint Progression of white matter hyperintensities in Alzheimer disease, dementia with lewy bodies, and Parkinson disease dementia: a comparison with normal aging
    Emma J Burton
    Institute for Ageing and Health, Wolfson Research Centre, Newcastle General Hospital, Newcastle upon Tyne, UK
    Am J Geriatr Psychiatry 14:842-9. 2006
    ..The objective of this study was to investigate cross-sectional and longitudinal white matter hyperintensity (WMH) changes in older subjects with clinically diagnosed dementia...
  10. doi request reprint Does posterior cortical atrophy on MRI discriminate between Alzheimer's disease, dementia with Lewy bodies, and normal aging?
    James O'Donovan
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    Int Psychogeriatr 25:111-9. 2013
    ..Therefore, we assessed whether visual rating scales for assessing posterior atrophy (PA), medial temporal lobe atrophy (MTA), and ventricular enlargement (VEn) aid in the discrimination between AD, DLB, and normal aging...
  11. pmc Neuroimaging predictors of death and dementia in a cohort of older stroke survivors
    Michael J Firbank
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK
    J Neurol Neurosurg Psychiatry 83:263-7. 2012
    ..Stroke is a risk factor for subsequent death and dementia. Being able to identify subjects at particular risk would be beneficial to inform treatment and patient management...
  12. ncbi request reprint Brain atrophy and white matter hyperintensity change in older adults and relationship to blood pressure. Brain atrophy, WMH change and blood pressure
    Michael J Firbank
    Institute for Ageing and Health, Wolfson Research Centre, Newcastle upon Tyne, NE4 6BE, UK
    J Neurol 254:713-21. 2007
    ..These changes are independent. Successful hypertension treatment was associated with reduced risk of WMH progression and possibly brain atrophy...
  13. doi request reprint A volumetric magnetic resonance imaging study of entorhinal cortex volume in dementia with lewy bodies. A comparison with Alzheimer's disease and Parkinson's disease with and without dementia
    Eva R Kenny
    Institute for Ageing and Health, Newcastle University, Wolfson Research Centre, Campus for Ageing and Vitality, Newcastle upon Tyne, UK
    Dement Geriatr Cogn Disord 26:218-25. 2008
    ....
  14. ncbi request reprint Cognitive associations of subcortical white matter lesions in older people
    John T O'Brien
    Institute for Ageing and Health, Wolfson Research Centre, University of Newcastle upon Tyne, Westgate Road, Newcastle upon Tyne NE4 6BE, UK
    Ann N Y Acad Sci 977:436-44. 2002
    ....
  15. ncbi request reprint The application of serial MRI analysis techniques to the study of cerebral atrophy in late-onset dementia
    S M Paling
    Institute for Ageing and Health, Newcastle General Hospital, Newcastle upon Tyne, UK
    Med Image Anal 8:69-79. 2004
    ..001) compared to controls. In general the analysis technique is shown to be a robust, accurate and transferable tool of potential value for future studies of dementia and related neuro-degenerative disorders...
  16. ncbi request reprint Atrophy of the putamen in dementia with Lewy bodies but not Alzheimer's disease: an MRI study
    D A Cousins
    Institute for Ageing and Health, Wolfson Research Centre, Newcastle General Hospital, Newcastle upon Tyne, UK
    Neurology 61:1191-5. 2003
    ....
  17. ncbi request reprint Medial temporal atrophy rather than white matter hyperintensities predict cognitive decline in stroke survivors
    Michael J Firbank
    Institute for Ageing and Health, University of Newcastle, Wolfson Research Centre, Newcastle upon Tyne NE4 6BE, UK
    Neurobiol Aging 28:1664-9. 2007
    ..The association of MTA but not WMH with subsequent cognitive decline and increasing brain atrophy suggests a greater role for Alzheimer type than vascular pathology in delayed cognitive impairment after stroke...
  18. ncbi request reprint Dementia with Lewy bodies and AD are not associated with occipital lobe atrophy on MRI
    H A Middelkoop
    Institute for Ageing and Health, University of Newcastle upon Tyne, UK
    Neurology 57:2117-20. 2001
    ..There were no significant differences between groups in occipital lobe volume. The authors conclude gross structural changes in the occipital lobe do not occur in patients with mild to moderate DLB or AD...
  19. ncbi request reprint High resolution imaging of the medial temporal lobe in Alzheimer's disease and dementia with lewy bodies
    Michael J Firbank
    Institute for Ageing and Health, Newcastle University, Newcastle, UK
    J Alzheimers Dis 21:1129-40. 2010
    ..Future studies should investigate whether subiculum thickness or the hypointense line could be a diagnostic feature to help discriminate AD from DLB...
  20. ncbi request reprint Hippocampal atrophy, whole brain volume, and white matter lesions in older hypertensive subjects
    R M Wiseman
    Institute for Aging and Health, University of Newcastle upon Tyne, UK
    Neurology 63:1892-7. 2004
    ..To determine the potential role of whole brain atrophy, hippocampal atrophy, or both, and small vessel disease/white matter lesions as mechanisms underlying the cognitive impairment associated with hypertension...
  21. ncbi request reprint White matter hyperintensities are associated with impairment of memory, attention, and global cognitive performance in older stroke patients
    Emma J Burton
    Institute for Ageing and Health, Newcastle General Hospital, Newcastle, UK
    Stroke 35:1270-5. 2004
    ..We hypothesized that processing speed and executive dysfunction will be associated with frontal WMH whereas impaired memory will be associated with temporal WMH...
  22. ncbi request reprint Comparing gray matter loss profiles between dementia with Lewy bodies and Alzheimer's disease using cortical pattern matching: diagnosis and gender effects
    Martina Ballmaier
    Laboratory of Neuroimaging, Department of Neurology, David Geffen UCLA School of Medicine, Los Angeles, CA 90095 1769, USA
    Neuroimage 23:325-35. 2004
    ..Further investigation of the influence of gender might provide a more comprehensive understanding of the pathophysiological differences underlying the two forms of dementia...
  23. ncbi request reprint MRI study of caudate nucleus volume in Parkinson's disease with and without dementia with Lewy bodies and Alzheimer's disease
    Osvaldo P Almeida
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Nedlands, Australia
    Dement Geriatr Cogn Disord 16:57-63. 2003
    ..To examine the relationship between caudate volume and cognitive impairment, depression and movement disorder...