Research Topics
| N BurgessSummaryAffiliation: University College London Country: UK Publications
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Detail Information
Publications
The hippocampus, space, and viewpoints in episodic memoryNeil Burgess
Institute of Cognitive Neuroscience and Department of Anatomy, University College London, UK
Q J Exp Psychol A 55:1057-80. 2002..I speculate that the hippocampal role in episodic recollection relates to its ability to represent a viewpoint moving within a spatial framework...
Characterizing multiple independent behavioral correlates of cell firing in freely moving animalsNeil Burgess
Department of Anatomy and Developmental Biology, University College London, United Kingdom
Hippocampus 15:149-53. 2005..2004); and to demonstrate the location-independence of the directional firing of head-direction cells...
Grid cells and theta as oscillatory interference: theory and predictionsNeil Burgess
Institute of Cognitive Neuroscience, University College London
Hippocampus 18:1157-74. 2008..Qualitative predictions are given for the properties of the VCOs, and the relationship between environmental novelty, the two components of theta, grid scale and place cell remapping...
Orientational manoeuvres in the dark: dissociating allocentric and egocentric influences on spatial memoryNeil Burgess
Institute of Cognitive Neuroscience, University College London, Alexandra House, 17 Queen Square, London W1N 3AR, UK
Cognition 94:149-66. 2004..These results enable a simple egocentric model of spatial memory to be extended to address large-scale navigation, including the effects of allocentric knowledge, landmark stability and gender...
The human hippocampus and spatial and episodic memoryNeil Burgess
Institute of Cognitive Neuroscience and Department of Anatomy and Developmental Biology, University College London, 17 Queen Square, London, United Kingdom
Neuron 35:625-41. 2002....
The theta rhythmNeil Burgess
Institute of Cognitive Neuroscience, Department of Anatomy and Developmental Biology, University College of London, UK
Hippocampus 15:825-6. 2005
Computational models of working memory: putting long-term memory into contextNeil Burgess
Institute of Cognitive Neuroscience and Department of Anatomy and Developmental Biology, University College London, 17 Queen Square, London, WC1N 3AR, UK
Trends Cogn Sci 9:535-41. 2005..We review some of these models, and discuss a common mechanism capable of modelling working memory and its interaction with long-term memory, focussing on memory for verbal sequences...
An oscillatory interference model of grid cell firingNeil Burgess
Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London, United Kingdom
Hippocampus 17:801-12. 2007..Predictions of the interference model are given for the frequency composition of EEG power spectra and temporal autocorrelograms of grid cell firing as functions of the speed and direction of running and the novelty of the environment...
Memory for events and their spatial context: models and experimentsN Burgess
Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London WC1N 3AR, UK
Philos Trans R Soc Lond B Biol Sci 356:1493-503. 2001..A neuropsychological experiment suggests that the hippocampus does store an allocentric representation of spatial locations...
Spatial cognition and the brainNeil Burgess
Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London WC1N 3AR, UK
Ann N Y Acad Sci 1124:77-97. 2008....
Predictions derived from modelling the hippocampal role in navigationN Burgess
Institute of Cognitive Neuroscience and Department of Anatomy, University College London, UK
Biol Cybern 83:301-12. 2000..A series of predictions for behavioural and single-unit data in rats are derived from the input and output representations of the model...
Impaired allocentric spatial memory underlying topographical disorientationNeil Burgess
Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London WC1N 3AR, UK
Rev Neurosci 17:239-51. 2006..The specificity of our test indicates a new way of assessing topographical disorientation, with possible application to the assessment of progressive dementias such as Alzheimer's disease...
Spatial memory: how egocentric and allocentric combineNeil Burgess
Institute of Cognitive Neuroscience and Department of Anatomy, University College London, 17 Queen Square, London WC1N 3AR, UK
Trends Cogn Sci 10:551-7. 2006..Identifying the neuronal mechanisms and functional roles of each type of representation, and of their interactions, promises to provide a framework for investigation of the organization of human memory more generally...
The representation of space and the hippocampus in rats, robots and humansN Burgess
Department of Anatomy, University College London, U K
Z Naturforsch C 53:504-9. 1998..The model's behaviour is compared to electrophysiological and behavioural data in rats, and implications for the role of the hippocampus in primates are explored...
Knowing where and getting there: a human navigation networkE A Maguire
Wellcome Department of Cognitive Neurology, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK
Science 280:921-4. 1998..These findings outline a network of brain areas that support navigation in humans and link the functions of these regions to physiological observations in other mammals...
Environmental novelty is signaled by reduction of the hippocampal theta frequencyA Jeewajee
Department of Anatomy and Developmental Biology, University College London, United Kingdom
Hippocampus 18:340-8. 2008....
Grid cells and theta as oscillatory interference: electrophysiological data from freely moving ratsA Jeewajee
Institute of Cognitive Neuroscience, University College London UCL, London, United Kingdom
Hippocampus 18:1175-85. 2008..They also provide specific constraints on this model of grid cell firing and have more general implications for viewing neuronal processing in terms of interfering oscillatory processes...
Bilateral hippocampal pathology impairs topographical and episodic memory but not visual pattern matchingH J Spiers
Institute of Cognitive Neuroscience, Department of Anatomy and Developmental Biology, University College London, UK
Hippocampus 11:715-25. 2001..These findings are consistent with the view that the hippocampus is involved in navigation, recall of long term allocentric spatial information and context-dependent episodic memory, but not visual pattern matching...
Attractor dynamics in the hippocampal representation of the local environmentTom J Wills
Department of Anatomy and Developmental Biology, University College London, London WC1E 6BT, UK
Science 308:873-6. 2005..This enables study of attractor dynamics in a cognitive representation and may correspond to the formation of distinct contexts in context-dependent memory...
Knowing where things are parahippocampal involvement in encoding object locations in virtual large-scale spaceE A Maguire
Wellcome Institute of Neurology, Department of Cognitive Neurology, London, UK, WC1N 3BG
J Cogn Neurosci 10:61-76. 1998....
The hippocampal role in spatial memory and the familiarity--recollection distinction: a case studyJohn A King
University College London, London, United Kingdom
Neuropsychology 18:405-17. 2004..These results are consistent with Jon having preserved matching to fixed sensory-bound representations but impaired reconstructed or manipulable representations underlying shifted-viewpoint recognition and episodic recollection...
A temporoparietal and prefrontal network for retrieving the spatial context of lifelike eventsN Burgess
Institute of Cognitive Neuroscience, Department of Anatomy, University College London, 17 Queen Square, London, WC1N 3AR, United Kingdom
Neuroimage 14:439-53. 2001..Prefrontal activations are consistent with strategic retrieval processes, including those required to overcome the interference between the highly similar events...
Experience-dependent rescaling of entorhinal gridsCaswell Barry
Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London WC1N 3AR, UK
Nat Neurosci 10:682-4. 2007..Thus grid scale reflects an interaction between intrinsic, path-integrative calculation of location and learned associations to the external environment...
Unilateral temporal lobectomy patients show lateralized topographical and episodic memory deficits in a virtual townH J Spiers
The Institute of Cognitive Neuroscience and the Department of Anatomy and Developmental Biology, University College London, London, UK
Brain 124:2476-89. 2001....
Human spatial navigation: cognitive maps, sexual dimorphism, and neural substratesE A Maguire
Wellcome Department of Cognitive Neurology, Institute of Neurology, University College London, 12 Queen Square, London, WC1N 3BG, UK
Curr Opin Neurobiol 9:171-7. 1999..Functional brain imaging, combined with the use of virtual environments, has revealed strong parallels between humans and other animals in the neural basis of navigation...
Independent rate and temporal coding in hippocampal pyramidal cellsJohn Huxter
Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK
Nature 425:828-32. 2003....
Modeling place fields in terms of the cortical inputs to the hippocampusT Hartley
Institute of Cognitive Neuroscience, University College London, UK
Hippocampus 10:369-79. 2000..The cells' behavior can be predicted for novel environments of arbitrary size and shape, or for manipulations such as introducing a barrier. The model can be extended to make behavioral predictions regarding spatial memory...
Hippocampal amnesiaH J Spiers
Institute of Cognitive Neuroscience and Department of Anatomy and Developmental Biology, 17 Queen Square, University College London, London WC1N 3AR, UK
Neurocase 7:357-82. 2001..The evidence concerning these issues is reviewed across cases...
The hippocampus is required for short-term topographical memory in humansTom Hartley
Institute of Cognitive Neuroscience, UCL, London, UK
Hippocampus 17:34-48. 2007....
Recoding, storage, rehearsal and grouping in verbal short-term memory: an fMRI studyR N Henson
Wellcome Department of Cognitive Neurology, Institute of Neurology, 12 Queen Square, London, UK
Neuropsychologia 38:426-40. 2000....
Neural bases of autobiographical support for episodic recollection of facesIris Trinkler
Institute of Cognitive Neuroscience, University College London, United Kingdom
Hippocampus 19:718-30. 2009....
Directional control of hippocampal place fieldsK J Jeffery
Department of Anatomy and Developmental Biology, University College London, UK
Exp Brain Res 117:131-42. 1997..When room cues were present, distal visual cues predominated over internal cues in establishing place field orientation...
Impaired memory for scenes but not faces in developmental hippocampal amnesia: a case studyChris M Bird
Institute of Cognitive Neuroscience, University College London, UK
Neuropsychologia 46:1050-9. 2008..Instead, the data indicate that the hippocampus plays a preferential role in the processing of topographical memoranda over faces memoranda...
Brain oscillations and memoryEmrah Duzel
UCL Institute of Cognitive Neuroscience, University College London, WC1N 3AR London, United Kingdom
Curr Opin Neurobiol 20:143-9. 2010..This correspondence between species opens new perspectives for a mechanistic investigation of human memory function...
Intrusive images in psychological disorders: characteristics, neural mechanisms, and treatment implicationsChris R Brewin
Research Department of Clinical, Educational and Health Psychology, University College London, Gower Street, London WC1E6BT, England
Psychol Rev 117:210-32. 2010..Finally, we discuss the treatment implications of the new model and relate it to existing forms of psychological therapy...
Learning in a geometric model of place cell firingCaswell Barry
Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London, United Kingdom
Hippocampus 17:786-800. 2007..2000a) J Gen Physiol 116:191-209) observation that inconsistent rotation of cue cards produces parametric changes in place field positions. The merits of the model are discussed in terms of its extensibility and biological plausibility...
Topographical short-term memory differentiates Alzheimer's disease from frontotemporal lobar degenerationChris M Bird
UCL Institute of Cognitive Neuroscience and UCL Institute of Neurology, London, United Kingdom
Hippocampus 20:1154-69. 2010....
The hippocampus supports recognition memory for familiar words but not unfamiliar facesChris M Bird
Institute of Cognitive Neuroscience, University College London, London, UK
Curr Biol 18:1932-6. 2008..By contrast, recognition memory for some kinds of previously unfamiliar stimuli (unfamiliar faces) may be supported by extrahippocampal familiarity-based processes, at least over short intervals...
The hippocampus and memory: insights from spatial processingChris M Bird
Institute of Cognitive Neuroscience and Department of Anatomy, University College London, London, WC1N 3AR, UK
Nat Rev Neurosci 9:182-94. 2008....
Evidence for grid cells in a human memory networkChristian F Doeller
UCL Institute of Cognitive Neuroscience, London WC1N 3AR, UK
Nature 463:657-61. 2010..Our results provide evidence for grid-cell-like representations in humans, and implicate a specific type of neural representation in a network of regions which supports spatial cognition and also autobiographical memory...
Distinct error-correcting and incidental learning of location relative to landmarks and boundariesChristian F Doeller
Institute of Cognitive Neuroscience, University College London, London WC1N 3AR, United Kingdom
Proc Natl Acad Sci U S A 105:5909-14. 2008..Finally, the demonstration that reinforcement learning applies selectively to formally equivalent aspects of task-performance supports broader consideration of two-system models in analyses of learning and decision making...
Acute effects of alcohol on intrusive memory development and viewpoint dependence in spatial memory support a dual representation modelJames A Bisby
Clinical Psychopharmacology Unit, University College London, United Kingdom
Biol Psychiatry 68:280-6. 2010..We tested the model by investigating the effect of alcohol on intrusive memories and, concurrently, on egocentric and allocentric spatial memory...
Developmental trajectories for spatial frames of reference in Williams syndromeMarko Nardini
Department of Psychology, University College London, UK
Dev Sci 11:583-95. 2008..Difficulties with inhibition or mental rotation may be further components in the impaired ability to use the correct reference frame in WS...
Establishing the boundaries: the hippocampal contribution to imagining scenesChris M Bird
UCL Institute of Cognitive Neuroscience and UCL Institute of Neurology, University College London, London, United Kingdom
J Neurosci 30:11688-95. 2010..Our findings identify a specific computational role for the hippocampus in mental imagery and episodic recollection...
Development of the hippocampal cognitive map in preweanling ratsTom J Wills
Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK
Science 328:1573-6. 2010..Stable grid cell firing appears later but matures rapidly to adult levels. Our results demonstrate the presence of three neuronal representations of space before extensive experience and show how they develop with age...
Parallel striatal and hippocampal systems for landmarks and boundaries in spatial memoryChristian F Doeller
Institute of Cognitive Neuroscience, University College London, London WC1N 3AR, United Kingdom
Proc Natl Acad Sci U S A 105:5915-20. 2008....
Navigation expertise and the human hippocampus: a structural brain imaging analysisEleanor A Maguire
Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, London, United Kingdom
Hippocampus 13:250-9. 2003....
Selective interference with verbal short-term memory for serial order information: a new paradigm and tests of a timing-signal hypothesisRichard Henson
Institute of Cognitive Neuroscience, University College London, London, UK
Q J Exp Psychol A 56:1307-34. 2003..Results are generally consistent with the timing-signal hypothesis but suggest further factors that need to be explored to distinguish it from other accounts...
Geometric determinants of human spatial memoryTom Hartley
Institute of Cognitive Neuroscience, London, UK
Cognition 94:39-75. 2004....
Theta-modulated place-by-direction cells in the hippocampal formation in the ratFrancesca Cacucci
Department of Anatomy and Developmental Biology, University College London, WC1N 3AR, London, United Kingdom
J Neurosci 24:8265-77. 2004....
The well-worn route and the path less traveled: distinct neural bases of route following and wayfinding in humansTom Hartley
Institute of Cognitive Neuroscience and Department of Anatomy and Developmental Biology, University College London, University College London, London, United Kingdom
Neuron 37:877-88. 2003..We argue that the type of representation used influences both performance and concomitant fMRI activation patterns...
Dual phase and rate coding in hippocampal place cells: theoretical significance and relationship to entorhinal grid cellsJohn O'Keefe
Department of Anatomy and Developmental Biology, University College London
Hippocampus 15:853-66. 2005..Finally, we propose a model of the firing of the recently discovered "grid cells" in entorhinal cortex as part of a path-integration system, in combination with place cells and head-direction cells...
Doing the right thing: a common neural circuit for appropriate violent or compassionate behaviorJohn A King
Institute of Cognitive Neuroscience and Department of Anatomy, University College London, 17 Queen Square, London WC1N 3AR, UK
Neuroimage 30:1069-76. 2006..The findings indicate a common system that guides behavioral expression appropriate to social or societal context irrespective of its aggressive or compassionate nature...
A metric for the cognitive map: found at last?Kathryn J Jeffery
Institute of Behavioural Neuroscience, Department of Psychology, University College London, 26 Bedford Way, London WC1H OAP, UK
Trends Cogn Sci 10:1-3. 2006..These "grid cells" might be the basis of a metric used for calculating position, and their discovery could greatly advance our understanding of how navigational computations are performed...
The boundary vector cell model of place cell firing and spatial memoryCaswell Barry
Institute of Cognitive Neuroscience, University College London, UK
Rev Neurosci 17:71-97. 2006..Simulations are compared to experimental data on the firing of place cells under geometrical manipulations to their environment. The relationship between neurophysiological results in rats and spatial behaviour in humans is discussed...
Human hippocampus and viewpoint dependence in spatial memoryJohn A King
Institute of Cognitive Neuroscience and Department of Anatomy, University College, London, United Kingdom
Hippocampus 12:811-20. 2002..In addition, they suggest an extremely sensitive test for human hippocampal damage, and hint at the nature of the hippocampal role in episodic recollection...
What can the hippocampal representation of environmental geometry tell us about Hebbian learning?Colin Lever
Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK
Biol Cybern 87:356-72. 2002..Our results identify a potential neural basis for long-term incidental learning of environments and provide strong constraints for the way the unsupervised learning in cell assemblies envisaged by Hebb might occur within the hippocampus...
Long-term plasticity in hippocampal place-cell representation of environmental geometryColin Lever
Department of Anatomy and Developmental Biology, University College London, WC1E 6BT, UK
Nature 416:90-4. 2002..These results indicate that place cells may be a neural substrate for long-term incidental learning, and demonstrate the long-term stability of an experience-dependent firing pattern in the hippocampal formation...
Effects of pre-experimental knowledge on recognition memoryChris M Bird
UCL Institute of Neurology and UCL Institute of Cognitive Neuroscience, University College London, London WC1N 3AR, United Kingdom
Learn Mem 18:11-4. 2011..Thus, pre-experimental knowledge has profound effects on the multiple, interacting processes that subserve recognition memory, and likely in the neural systems that underpin them...
Visual influence on path integration in darkness indicates a multimodal representation of large-scale spaceLili Tcheang
UCL Institute of Cognitive Neuroscience, University College London, London WC1N 3AR, United Kingdom
Proc Natl Acad Sci U S A 108:1152-7. 2011..Overall, our findings suggest that a combined multimodal representation guides large-scale navigation, consistent with a role for visual imagery or a cognitive map...
Anterior prefrontal involvement in episodic retrieval reflects contextual interferenceJ A King
Institute of Cognitive Neuroscience and Department of Anatomy and Developmental Biology, University College London, UK
Neuroimage 28:256-67. 2005....
Differential developmental trajectories for egocentric, environmental and intrinsic frames of reference in spatial memoryMarko Nardini
Department of Psychology, University College London, Gower Street, London WC1E 6BT, UK
Cognition 101:153-72. 2006..These are supplemented by later-developing object-referenced representations...
Complementary memory systems: competition, cooperation and compensationTom Hartley
Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London WC1N 3AR, UK
Trends Neurosci 28:169-70. 2005..g. finding new shortcuts), and depends on the hippocampus. Voermans and colleagues explore the interaction between these two systems using functional neuroimaging and behavioural measures in a clinical population...
Parallel memory systems for talking about location and age in precuneus, caudate and Broca's regionMikkel Wallentin
Center for Functionally Integrative Neuroscience, Aarhus University Hospital, Nørrebrogade, 8000 Aarhus C, Denmark
Neuroimage 32:1850-64. 2006..These findings indicate that multiple parallel memory systems are available during language processing, appropriate for different tasks, with performance reflecting which system is selected trial-by-trial and subject-by-subject...
Performance on a virtual reality spatial memory navigation task in depressed patientsNeda F Gould
Laboratory of Molecular Pathophysiology, Mood and Anxiety Disorders Program, NIMH, Mark O Hatfield Clinical Research Center, 10 Center Dr, Bethesda, MD 20892, USA
Am J Psychiatry 164:516-9. 2007..Findings on spatial memory in depression have been inconsistent. A navigation task based on virtual reality may provide a more sensitive and consistent measure of the hippocampal-related spatial memory deficits associated with depression...
Frontal eye fields involved in shifting frame of reference within working memory for scenesMikkel Wallentin
Center for Functionally Integrative Neuroscience, Aarhus University Hospital, Nørrebrogade, 8000 Aarhus C, Denmark
Neuropsychologia 46:399-408. 2008..Thus, the FEF machinery for directing eye movements may also be involved in changing reference frames within WM...
Neurodevelopmental aspects of spatial navigation: a virtual reality fMRI studyDaniel S Pine
Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Building 10, Room 4N-222 [MSC1381, Bethesda, Maryland 20892-1381, USA
Neuroimage 15:396-406. 2002..Consistent with developmental models, these findings relate maturation in the coding of spatial information to functional changes in a distributed, left-lateralized neural network...
Children reorient using the left/right sense of coloured landmarks at 18-24 monthsMarko Nardini
Department of Experimental Psychology, Oxford University, South Parks Road, Oxford OX1 3UD, UK
Cognition 106:519-27. 2008..The relatively poor use of colour in previous studies may be explained partly by a bias in their design, and partly by children's limited ability to discriminate the left/right sense of nongeometric features...
Remembering the past and imagining the future: a neural model of spatial memory and imageryPatrick Byrne
Department of Psychology, Neuroscience and Behaviour, McMaster University, Hamilton, ON, Canada
Psychol Rev 114:340-75. 2007....
