A Buckling

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. pmc Antagonistic coevolution between a bacterium and a bacteriophage
    Angus Buckling
    Department of Plant Sciences, University of Oxford, Oxford OX1 3RB, UK
    Proc Biol Sci 269:931-6. 2002
  2. pmc Differential impact of simultaneous migration on coevolving hosts and parasites
    Andrew D Morgan
    Department of Zoology, University of Oxford, Oxford, UK
    BMC Evol Biol 7:1. 2007
  3. pmc Cooperation and virulence in acute Pseudomonas aeruginosa infections
    Freya Harrison
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    BMC Biol 4:21. 2006
  4. pmc Resource supply and the evolution of public-goods cooperation in bacteria
    Michael A Brockhurst
    School of Biological Sciences, Biosciences Building, University of Liverpool, Crown Street, Liverpool, L69 7ZB, UK
    BMC Biol 6:20. 2008
  5. doi request reprint The Beagle in a bottle
    Angus Buckling
    Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
    Nature 457:824-9. 2009
  6. doi request reprint Kin selection and the evolution of virulence
    A Buckling
    Department of Zoology, University of Oxford, Oxford, UK
    Heredity (Edinb) 100:484-8. 2008
  7. ncbi request reprint Coevolution with viruses drives the evolution of bacterial mutation rates
    Csaba Pal
    Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
    Nature 450:1079-81. 2007
  8. ncbi request reprint Siderophore-mediated cooperation and virulence in Pseudomonas aeruginosa
    Angus Buckling
    Department of Zoology, University of Oxford, Oxford, UK
    FEMS Microbiol Ecol 62:135-41. 2007
  9. ncbi request reprint Short-term rates of parasite evolution predict the evolution of host diversity
    A Buckling
    Department of Zoology, University of Oxford, Oxford, UK
    J Evol Biol 20:1682-8. 2007
  10. ncbi request reprint The interactive effects of parasites, disturbance, and productivity on experimental adaptive radiations
    Rebecca Benmayor
    Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom
    Evolution 62:467-77. 2008

Detail Information

Publications72

  1. pmc Antagonistic coevolution between a bacterium and a bacteriophage
    Angus Buckling
    Department of Plant Sciences, University of Oxford, Oxford OX1 3RB, UK
    Proc Biol Sci 269:931-6. 2002
    ..Coevolution followed divergent trajectories between replicate communities despite establishment with isogenic bacteria and phage, and resulted in bacteria adapted to their own, compared with other, phage populations...
  2. pmc Differential impact of simultaneous migration on coevolving hosts and parasites
    Andrew D Morgan
    Department of Zoology, University of Oxford, Oxford, UK
    BMC Evol Biol 7:1. 2007
    ..However, previous studies suggest phages should benefit more from migration than bacteria; because in the absence of migration, phages are more genetically limited and have a lower evolutionary potential compared to the bacteria...
  3. pmc Cooperation and virulence in acute Pseudomonas aeruginosa infections
    Freya Harrison
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    BMC Biol 4:21. 2006
    ..We tested this hypothesis using the cooperative production of iron-scavenging siderophores by the pathogenic bacterium Pseudomonas aeruginosa in an insect host...
  4. pmc Resource supply and the evolution of public-goods cooperation in bacteria
    Michael A Brockhurst
    School of Biological Sciences, Biosciences Building, University of Liverpool, Crown Street, Liverpool, L69 7ZB, UK
    BMC Biol 6:20. 2008
    ....
  5. doi request reprint The Beagle in a bottle
    Angus Buckling
    Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
    Nature 457:824-9. 2009
    ..Potential future directions for the approach include studying microbial evolution for its own sake under the most natural conditions possible in the test tube, and testing some qualitative theories of genome evolution...
  6. doi request reprint Kin selection and the evolution of virulence
    A Buckling
    Department of Zoology, University of Oxford, Oxford, UK
    Heredity (Edinb) 100:484-8. 2008
    ..We highlight the need for further thorough experimentation on the role of kin selection in the evolution of virulence and identify additional biological complexities to these simple frameworks...
  7. ncbi request reprint Coevolution with viruses drives the evolution of bacterial mutation rates
    Csaba Pal
    Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
    Nature 450:1079-81. 2007
    ..Given their ubiquity, bacteriophages may play an important role in the evolution of bacterial mutation rates...
  8. ncbi request reprint Siderophore-mediated cooperation and virulence in Pseudomonas aeruginosa
    Angus Buckling
    Department of Zoology, University of Oxford, Oxford, UK
    FEMS Microbiol Ecol 62:135-41. 2007
    ..Fourth, cooperative pyoverdin production is also shown to be favoured by kin selection in vivo (caterpillars), and results in more virulent infections. Finally, we briefly outline ongoing and future work using this experimental system...
  9. ncbi request reprint Short-term rates of parasite evolution predict the evolution of host diversity
    A Buckling
    Department of Zoology, University of Oxford, Oxford, UK
    J Evol Biol 20:1682-8. 2007
    ..This study demonstrates that short-term changes in the rate of parasite evolution can predictably drive patterns of host diversity...
  10. ncbi request reprint The interactive effects of parasites, disturbance, and productivity on experimental adaptive radiations
    Rebecca Benmayor
    Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom
    Evolution 62:467-77. 2008
    ..Parasites and other natural enemies are therefore likely to have a large effect in mitigating the influence of other environmental variables on the evolution and maintenance of diversity...
  11. pmc The effect of spatial heterogeneity and parasites on the evolution of host diversity
    Michael A Brockhurst
    Department of Plant Sciences, University of Oxford, South Parks Road, Oxford OX1 3RB, UK
    Proc Biol Sci 271:107-11. 2004
    ..Such interactions between key ecological variables need to be considered when addressing diversification and coexistence in future studies...
  12. doi request reprint Effects of antagonistic coevolution on parasite-mediated host coexistence
    A D Morgan
    Department of Zoology, University of Oxford, Oxford, UK
    J Evol Biol 22:287-92. 2009
    ..These results demonstrate that the stability of parasite-mediated coexistence of resistant and susceptible species or genotypes is likely to be affected if parasites and susceptible hosts coevolve...
  13. doi request reprint No effect of host-parasite co-evolution on host range expansion
    P D Scanlan
    Department of Zoology, University of Oxford, Oxford, UK
    J Evol Biol 26:205-9. 2013
    ..fluorescens strains. Thus, parasite generalism at one genetic scale does not appear to affect generalism at other scales, suggesting fundamental genetic constraints on parasite adaptation for this virus...
  14. doi request reprint Abiotic heterogeneity drives parasite local adaptation in coevolving bacteria and phages
    L Lopez Pascua
    Department of Zoology, University of Oxford, Oxford, UK
    J Evol Biol 25:187-95. 2012
    ..These results demonstrate that the abiotic environment can play a strong and predictable role in driving patterns of local adaptation...
  15. doi request reprint The rate of environmental change drives adaptation to an antibiotic sink
    G G Perron
    Department of Zoology, University of Oxford, Oxford, UK
    J Evol Biol 21:1724-31. 2008
    ..These findings, which support recent theoretical work, have important implications for the control of antibiotic resistance because they show that rapid rates of change can produce variants with the ability to resist future treatments...
  16. ncbi request reprint Experimental adaptation to high and low quality environments under different scales of temporal variation
    A Buckling
    Department of Plant Sciences, University of Oxford, Oxford, UK
    J Evol Biol 20:296-300. 2007
    ..Populations evolved only in high or low quality media did not show fitness improvements in their nonselective media. These results indicate that cost-free generalists can evolve under a wide range of temporal variation...
  17. ncbi request reprint Chloroquine increases Plasmodium falciparum gametocytogenesis in vitro
    A Buckling
    Institute of Cell, Animal and Population Biology, Division of Biological Sciences, University of Edinburgh, UK
    Parasitology 118:339-46. 1999
    ..This was not, however, associated with chloroquine resistance. The epidemiological significance of these results is discussed...
  18. ncbi request reprint Plasmodium chabaudi: effect of antimalarial drugs on gametocytogenesis
    A Buckling
    Institute of Cell, Animal and Population Biology, Division of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, United Kingdom
    Exp Parasitol 93:45-54. 1999
    ....
  19. ncbi request reprint Phenotypic switching of antibiotic resistance circumvents permanent costs in Staphylococcus aureus
    R C Massey
    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
    Curr Biol 11:1810-4. 2001
    ..aureus with stable gentamicin resistance was greater in drug-free media, which suggests that S. aureus has evolved an inducible and reversible resistance mechanism that circumvents a permanent cost to fitness...
  20. pmc High relatedness selects against hypermutability in bacterial metapopulations
    Freya Harrison
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Proc Biol Sci 274:1341-7. 2007
    ..These results may help to explain clinical distributions of mutator bacteria...
  21. ncbi request reprint Competition and dispersal in Pseudomonas aeruginosa
    Tiffany B Taylor
    Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom
    Am Nat 176:83-9. 2010
    ..Consistent with theory, the benefit of dispersal was much higher in clonal populations, and this benefit decreased with increasing growth rate costs associated with dispersal...
  22. ncbi request reprint Cooperative production of siderophores by Pseudomonas aeruginosa
    Freya Harrison
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS UK
    Front Biosci (Landmark Ed) 14:4113-26. 2009
    ..It is our hope that more realistic laboratory studies of siderophore cooperation in P. aeruginosa will eventually cast light on the roles played by social traits in long-term microbial infections...
  23. doi request reprint Hypermutability and compensatory adaptation in antibiotic-resistant bacteria
    Gabriel G Perron
    Department of Zoology, University of Oxford, United Kingdom
    Am Nat 176:303-11. 2010
    ..These results suggest that selection for mutations that offset the fitness cost associated with antibiotic resistance may help to explain the high frequency of mutator bacteria and antibiotic resistance observed in chronic infections...
  24. doi request reprint Impact of bacterial mutation rate on coevolutionary dynamics between bacteria and phages
    Andrew D Morgan
    Department of Zoology, University of Oxford, South Parks Road, Oxford, United Kingdom
    Evolution 64:2980-7. 2010
    ..More generally, the results demonstrate that coevolving enemies may escape from Red-Queen dynamics...
  25. doi request reprint The population genetics of antibiotic resistance: integrating molecular mechanisms and treatment contexts
    R Craig MacLean
    Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
    Nat Rev Genet 11:405-14. 2010
    ..However, putting these models to practical use will require extensive collaboration between mathematicians, molecular biologists, evolutionary ecologists and clinicians...
  26. doi request reprint Interspecific competition and siderophore-mediated cooperation in Pseudomonas aeruginosa
    Freya Harrison
    Department of Zoology, University of Oxford, Oxford, UK
    ISME J 2:49-55. 2008
    ..This is probably because the S. aureus had the net effect of competing for iron, rather than acting as an iron source. This study demonstrates that interspecific competition can have a marked effect on intraspecific social interactions...
  27. pmc Protists have divergent effects on bacterial diversity along a productivity gradient
    Thomas Bell
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Biol Lett 6:639-42. 2010
    ..Bodo and Cyclidium had little effect on the shape of the productivity-diversity gradient, while Spumella flattened the relationship. We explain these results in terms of the feeding preferences of these predators...
  28. doi request reprint Local adaptation of bacteriophages to their bacterial hosts in soil
    Michiel Vos
    Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
    Science 325:833. 2009
    ..This study demonstrates the importance of biotic interactions for the small-scale spatial structuring of microbial genetic diversity in soil...
  29. doi request reprint Coevolution between cooperators and cheats in a microbial system
    Quan Guo Zhang
    Department of Zoology, University of Oxford, Oxford, UK
    Evolution 63:2248-56. 2009
    ..Such coevolution may have important consequences for the maintenance of cooperation...
  30. doi request reprint A social life for discerning microbes
    Sam P Brown
    Department of Zoology, University of Oxford, Oxford, UK
    Cell 135:600-3. 2008
    ..2008; Diggle et al., 2007) and, most recently, has provided insights into the molecular mechanisms of discrimination in yeast (Smukalla et al., 2008)...
  31. pmc The distribution of fitness effects of beneficial mutations in Pseudomonas aeruginosa
    R Craig MacLean
    Department of Zoology, University of Oxford, Oxford, United Kingdom
    PLoS Genet 5:e1000406. 2009
    ....
  32. ncbi request reprint The effect of migration on local adaptation in a coevolving host-parasite system
    Andrew D Morgan
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Nature 437:253-6. 2005
    ..However, in accord with our model, parasite migration results in parasite local adaptation, but host migration alone has no significant effect...
  33. ncbi request reprint Hypermutability impedes cooperation in pathogenic bacteria
    Freya Harrison
    Department of Zoology, University of Oxford, United Kingdom
    Curr Biol 15:1968-71. 2005
    ..Cheats appeared and increased in frequency more rapidly in mutator populations. The presence of cheats was costly to the group, as shown by a negative correlation between cheat frequency and population density...
  34. ncbi request reprint Environmental regulation of mutation rates at specific sites
    Ruth C Massey
    Nuffield Dept of Clinical Laboratory Sciences, University of Oxford, Level 4, John Radcliffe Hospital, UK
    Trends Microbiol 10:580-4. 2002
    ..Here, we review these findings and discuss the circumstances under which these mechanisms might prove advantageous...
  35. pmc Source-sink dynamics shape the evolution of antibiotic resistance and its pleiotropic fitness cost
    Gabriel G Perron
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Proc Biol Sci 274:2351-6. 2007
    ....
  36. pmc Wider access to genotypic space facilitates loss of cooperation in a bacterial mutator
    Freya Harrison
    Department of Zoology, University of Oxford, Oxford, United Kingdom
    PLoS ONE 6:e17254. 2011
    ..This may represent a novel cost of hypermutability...
  37. doi request reprint Genetic basis of infectivity evolution in a bacteriophage
    Pauline D Scanlan
    Department of Zoology, South Parks Road, University of Oxford, Oxford OX1 3PS, UK
    Mol Ecol 20:981-9. 2011
    ..An understanding of the molecular genetics of phage infectivity has helped to explain the complex phenotypic coevolutionary dynamics in this system...
  38. doi request reprint Bacteria-phage antagonistic coevolution in soil
    Pedro Gomez
    Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
    Science 332:106-9. 2011
    ..These results suggest that rapid coevolution between bacteria and phage is likely to play a key role in structuring natural microbial communities...
  39. doi request reprint Bacteria-phage coevolution and the emergence of generalist pathogens
    Alex R Hall
    Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom
    Am Nat 177:44-53. 2011
    ....
  40. ncbi request reprint Relative number of generations of hosts and parasites does not influence parasite local adaptation in coevolving populations of bacteria and phages
    A D Morgan
    Department of Zoology, University of Oxford, Oxford, UK
    J Evol Biol 19:1956-63. 2006
    ..Taken together, these data suggest that the relative generation times of hosts and parasites may not be an important determinant of local adaptation in this system...
  41. ncbi request reprint Disturbance and diversity in experimental microcosms
    A Buckling
    Department of Plant Sciences, University of Oxford, UK
    Nature 408:961-4. 2000
    ..Our results show that disturbance can modulate the effect of spatial heterogeneity on biological diversity in natural environments...
  42. doi request reprint Antagonistic coevolution across productivity gradients: an experimental test of the effects of dispersal
    L d C Lopez-Pascua
    Department of Zoology, University of Oxford, Oxford, UK
    J Evol Biol 23:207-11. 2010
    ..Coevolutionary interactions in high-productivity environments are therefore likely to have a disproportionate impact on coevolution across the landscape as a whole...
  43. doi request reprint Increasing productivity accelerates host-parasite coevolution
    L d C Lopez-Pascua
    Department of Zoology, University of Oxford, Oxford, UK
    J Evol Biol 21:853-60. 2008
    ..The data further suggest that variation in productivity can generate variation in selection for resistance across landscapes, a result that is crucial to the geographic mosaic theory of coevolution...
  44. pmc Spite and virulence in the bacterium Pseudomonas aeruginosa
    R Fredrik Inglis
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom
    Proc Natl Acad Sci U S A 106:5703-7. 2009
    ..These results suggest that spiteful interactions may play an important role in the population dynamics and virulence of natural bacterial infections...
  45. ncbi request reprint Epidemiology. Keep it local
    Angus Buckling
    Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
    Science 315:1227-8. 2007
  46. pmc The effect of a bacteriophage on diversification of the opportunistic bacterial pathogen, Pseudomonas aeruginosa
    Michael A Brockhurst
    Department of Plant Sciences, University of Oxford, South Parks Road, Oxford OX1 3RB, UK
    Proc Biol Sci 272:1385-91. 2005
    ..Further assays revealed there to be two distinct types of resistant bacteria; these had very different ecological phenotypes, yet each carried a cost of resistance...
  47. doi request reprint Multiplicity of infection does not accelerate infectivity evolution of viral parasites in laboratory microcosms
    A R Hall
    Department of Zoology, University of Oxford, Oxford, UK College of Life and Environmental Sciences, University of Exeter, Cornwall Campus, Penryn, UK
    J Evol Biol 25:409-15. 2012
    ..This suggests that MOI does not have a net effect of accelerating parasite adaptation to hosts through recombination, or slowing adaptation to hosts through between-parasite conflict in this system...
  48. ncbi request reprint In vitro tests of natural allelic variation of innate immune genes (avian β-defensins) reveal functional differences in microbial inhibition
    O Hellgren
    Department of Zoology, Edward Grey Institute, University of Oxford, Oxford, UK
    J Evol Biol 23:2726-30. 2010
    ..Our data demonstrate functional allelic variation in natural defensin genes, and we discuss how differences in efficacy against microbial species might contribute to maintaining this variation...
  49. pmc Antagonistic coevolution with parasites increases the cost of host deleterious mutations
    Angus Buckling
    Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
    Proc Biol Sci 273:45-9. 2006
    ..These data suggest that coevolution with parasites increases the rate at which deleterious mutations are purged from host populations...
  50. doi request reprint Siderophore production and biofilm formation as linked social traits
    Freya Harrison
    Department of Zoology, University of Oxford, Oxford, UK
    ISME J 3:632-4. 2009
    ..Reduced biofilm formation therefore represents a pleiotropic cost of defection from siderophore production...
  51. pmc Identification of factors contributing to T-cell toxicity of Staphylococcus aureus clinical isolates
    James Collins
    Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom
    J Clin Microbiol 46:2112-4. 2008
    ..We found that the beta and delta hemolysins are involved and that methicillin-resistant S. aureus strains are less toxic than methicillin-susceptible S. aureus strains...
  52. ncbi request reprint Spatial heterogeneity and the stability of host-parasite coexistence
    M A Brockhurst
    Department of Plant Sciences, University of Oxford, South Parks Road, Oxford, UK
    J Evol Biol 19:374-9. 2006
    ..These results suggest that spatial heterogeneity can stabilize an otherwise unstable host-parasite interaction even in the absence of permanent spatial refuges...
  53. pmc Clonal distribution and phase-variable expression of a major histocompatibility complex analogue protein in Staphylococcus aureus
    Angus Buckling
    Department of Zoology, University of Oxford, South Parks Rd, Oxford OX1 3PS, UK
    J Bacteriol 187:2917-9. 2005
    ..This study demonstrates that mapW is an allelic variant of the map/eap genes found in other strains and that the variation in the length of this poly(A) tract suggests that it is a contingency locus...
  54. doi request reprint Host mixing and disease emergence
    Rebecca Benmayor
    Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
    Curr Biol 19:764-7. 2009
    ..These results suggest that adaptation to novel hosts can occur only under very specific ecological conditions, and that small changes in contact rates between host species might help to mitigate disease emergence...
  55. pmc Mechanisms linking diversity, productivity and invasibility in experimental bacterial communities
    David J Hodgson
    Ecology Group, CEH Oxford, Mansfield Road, Oxford OX1 3SR, UK
    Proc Biol Sci 269:2277-83. 2002
    ..In the absence of the dominance effect, which may be an experimental artefact, decreasing diversity can have unexpected or no effects on ecosystem properties...
  56. ncbi request reprint The role of parasites in sympatric and allopatric host diversification
    Angus Buckling
    Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK
    Nature 420:496-9. 2002
    ..These results show that exploiters can drive diversification between populations, but may inhibit diversification within populations by opposing diversifying selection that arises from resource competition...
  57. pmc Cooperation, virulence and siderophore production in bacterial parasites
    Stuart A West
    Institute of Cell, Animal and Population Biology, University of Edinburgh, King s Buildings, West Mains Road, Edinburgh EH9 3JT, UK
    Proc Biol Sci 270:37-44. 2003
    ....
  58. ncbi request reprint The impact of migration from parasite-free patches on antagonistic host-parasite coevolution
    Michael A Brockhurst
    School of Biological Sciences, Biosciences Building, University of Liverpool, Crown Street, Liverpool L69 7ZB, United Kingdom
    Evolution 61:1238-43. 2007
    ....
  59. pmc Interference competition and parasite virulence
    Ruth C Massey
    Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, UK
    Proc Biol Sci 271:785-8. 2004
    ..The ubiquity and diversity of bacteriocins among pathogenic bacteria suggest mixed infections will be, on average, less virulent than single infections...
  60. ncbi request reprint Cooperation peaks at intermediate disturbance
    Michael A Brockhurst
    School of Biological Sciences, Biosciences Building, University of Liverpool, Crown Street, Liverpool, L69 7ZB, UK
    Curr Biol 17:761-5. 2007
    ..Given the ubiquity of disturbances in nature, these results suggest that they may play a major role in the evolution of social traits in microbes...
  61. ncbi request reprint The evolution of specificity in evolving and coevolving antagonistic interactions between a bacteria and its phage
    Virginie Poullain
    Institut des Sciences de l Evolution UM2 CNRS, Universite Montpellier II, Place Eugene Bataillon, 34095, Montpellier, France
    Evolution 62:1-11. 2008
    ....
  62. ncbi request reprint Character displacement promotes cooperation in bacterial biofilms
    Michael A Brockhurst
    School of Biological Sciences, Biosciences Building, University of Liverpool, Crown Street, Liverpool L69 7ZB, United Kingdom
    Curr Biol 16:2030-4. 2006
    ..These results demonstrate that diversification into different ecological niches can minimize selection against cooperation in the face of local resource competition...
  63. ncbi request reprint Microbiology: RAMP resistance
    Angus Buckling
    Nature 438:170-1. 2005
  64. ncbi request reprint Microbial experiments on adaptive landscapes
    Nick Colegrave
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, UK
    Bioessays 27:1167-73. 2005
    ..Laboratory populations of microbes allow evolution to be observed in real time and, as such, provide key insights into the topology of adaptive landscapes...
  65. ncbi request reprint Cooperation and competition in pathogenic bacteria
    Ashleigh S Griffin
    Institute of Cell, Animal and Population Biology, University of Edinburgh, King s Buildings, West Mains Road, Edinburgh EH9 3JT, UK
    Nature 430:1024-7. 2004
    ....
  66. ncbi request reprint Adaptation limits diversification of experimental bacterial populations
    Angus Buckling
    Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK
    Science 302:2107-9. 2003
    ..Subsequent experiments demonstrated that niche generalists and reductions in intrinsic evolvability were not responsible for our data. These results show that niche specialization may come with a cost of reduced potential to diversify...
  67. pmc Bacteriocins, spite and virulence
    Andy Gardner
    Institute of Cell, Animal and Population Biology, University of Edinburgh, King s Buildings, West Mains Road, Edinburgh EH9 3JT, UK
    Proc Biol Sci 271:1529-35. 2004
    ..This emphasizes how biological details can fundamentally alter the qualitative nature of theoretical predictions made by models of parasite virulence...
  68. ncbi request reprint Experimental coevolution with bacteria and phage. The Pseudomonas fluorescens--Phi2 model system
    Michael A Brockhurst
    School of Biological Sciences, Biosciences Building, University of Liverpool, Liverpool L69 7ZB, UK
    Infect Genet Evol 7:547-52. 2007
    ..In this article we describe this model system and synthesise recent findings that address the causes and consequences of antagonistic coevolution...
  69. ncbi request reprint DDT resistance in flies carries no cost
    Caroline McCart
    Curr Biol 15:R587-9. 2005
  70. pmc Surface plasmon resonance shows that type IV pili are important in surface attachment by Pseudomonas aeruginosa
    A Toby A Jenkins
    Departments of Chemistry and Biology, University of Bath, Bath BA2 7AY, UK
    J R Soc Interface 2:255-9. 2005
    ..These results highlight the power of SPR in monitoring bacterial attachment in real time and also demonstrate an additional role for type IV pili beyond bacterial aggregation and micro-colony formation...
  71. pmc Agr interference between clinical Staphylococcus aureus strains in an insect model of virulence
    Vicki Fleming
    Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom
    J Bacteriol 188:7686-8. 2006
    ..Here, using the insect Manduca sexta, we show for the first time that this interference also occurs in vivo within a mixed population...
  72. ncbi request reprint Study of the attachment of Pseudomonas aeruginosa on gold and modified gold surfaces using surface plasmon resonance
    A Toby A Jenkins
    Department of Chemistry and Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, U K
    Biotechnol Prog 20:1233-6. 2004
    ..Finally, a qualitative correlation between results from SPR with a crystal violet staining assay for different mutant bacteria was observed...