Keith J Buckler


Affiliation: University of Oxford
Country: UK


  1. Buckler K, Vaughan Jones R. Effects of mitochondrial uncouplers on intracellular calcium, pH and membrane potential in rat carotid body type I cells. J Physiol. 1998;513 ( Pt 3):819-33 pubmed
    ..These effects are unlikely to be caused by cell acidification. The inhibition of background K+ current may be related to the uncoupling of oxidative phosphorylation. ..
  2. Buckler K. Two-pore domain k(+) channels and their role in chemoreception. Adv Exp Med Biol. 2010;661:15-30 pubmed publisher
    ..Moreover these channels seem often (albeit not exclusively) to be involved in pH and nutrient/metabolic sensing. ..
  3. Buckler K, Williams B, Honore E. An oxygen-, acid- and anaesthetic-sensitive TASK-like background potassium channel in rat arterial chemoreceptor cells. J Physiol. 2000;525 Pt 1:135-42 pubmed
    ..Using in situ hybridisation TASK-1 mRNA was found to be expressed in type-I cells. We conclude that the oxygen- and acid-sensitive background K+ channel of carotid body type-I cells is likely to be an endogenous TASK-1-like channel. ..