Caroline O Buckee

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. pmc The effects of host contact network structure on pathogen diversity and strain structure
    Caroline O F Buckee
    Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom
    Proc Natl Acad Sci U S A 101:10839-44. 2004
  2. ncbi request reprint Modelling malaria population structure and its implications for control
    Caroline O Buckee
    Department of Zoology, University of Oxford, South Parks Road, Oxford, UK, OX1 3PS
    Adv Exp Med Biol 673:112-26. 2010
  3. pmc Long-term evolution of antigen repertoires among carried meningococci
    Caroline O Buckee
    Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
    Proc Biol Sci 277:1635-41. 2010
  4. pmc Inferring malaria parasite population structure from serological networks
    Caroline O Buckee
    Department of Zoology, University of Oxford, Tinbergen Building, South Parks Road, Oxford OX1 3PS, UK
    Proc Biol Sci 276:477-85. 2009
  5. pmc Host community structure and the maintenance of pathogen diversity
    Caroline Buckee
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Proc Biol Sci 274:1715-21. 2007
  6. pmc The effect of immune selection on the structure of the meningococcal opa protein repertoire
    Martin J Callaghan
    Department of Paediatrics, University of Oxford, Centre for Clinical Vaccinology and Tropical Medicine CCVTM, Churchill Hospital, Oxford, United Kingdom
    PLoS Pathog 4:e1000020. 2008
  7. pmc Role of selection in the emergence of lineages and the evolution of virulence in Neisseria meningitidis
    Caroline O Buckee
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom
    Proc Natl Acad Sci U S A 105:15082-7. 2008
  8. pmc The effects of a partitioned var gene repertoire of Plasmodium falciparum on antigenic diversity and the acquisition of clinical immunity
    Mario Recker
    Department of Zoology, South Parks Road, OX1 3PS, Oxford, UK
    Malar J 7:18. 2008
  9. pmc Antigenic variation in Plasmodium falciparum malaria involves a highly structured switching pattern
    Mario Recker
    Department of Zoology, University of Oxford, Oxford, United Kingdom
    PLoS Pathog 7:e1001306. 2011
  10. pmc Opa protein repertoires of disease-causing and carried meningococci
    Martin J Callaghan
    Dept of Paediatrics, Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Churchill Hospital, Headington, Oxford OX3 9DU, United Kingdom
    J Clin Microbiol 46:3033-41. 2008

Detail Information

Publications13

  1. pmc The effects of host contact network structure on pathogen diversity and strain structure
    Caroline O F Buckee
    Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom
    Proc Natl Acad Sci U S A 101:10839-44. 2004
    ..These results imply that host contact network structure plays a significant role in mediating the emergence of pathogen strain structure and dynamics...
  2. ncbi request reprint Modelling malaria population structure and its implications for control
    Caroline O Buckee
    Department of Zoology, University of Oxford, South Parks Road, Oxford, UK, OX1 3PS
    Adv Exp Med Biol 673:112-26. 2010
    ..Lastly, we discuss the current sequence data on parasite antigen genes that are important for the aquisition of immunity, and the results of a new analysis of P. falciparum population structure at the genomic level...
  3. pmc Long-term evolution of antigen repertoires among carried meningococci
    Caroline O Buckee
    Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
    Proc Biol Sci 277:1635-41. 2010
    ..We contrast this antigenic structure with the overlapping but relatively stable combinations of the housekeeping genes observed among the same isolates, and use a novel network approach to visualize these relationships...
  4. pmc Inferring malaria parasite population structure from serological networks
    Caroline O Buckee
    Department of Zoology, University of Oxford, Tinbergen Building, South Parks Road, Oxford OX1 3PS, UK
    Proc Biol Sci 276:477-85. 2009
    ..Our analysis suggests that different levels of immune selection occur within different groups of the same multigene family leading to mixed population structures...
  5. pmc Host community structure and the maintenance of pathogen diversity
    Caroline Buckee
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Proc Biol Sci 274:1715-21. 2007
    ....
  6. pmc The effect of immune selection on the structure of the meningococcal opa protein repertoire
    Martin J Callaghan
    Department of Paediatrics, University of Oxford, Centre for Clinical Vaccinology and Tropical Medicine CCVTM, Churchill Hospital, Oxford, United Kingdom
    PLoS Pathog 4:e1000020. 2008
    ..These data are consistent with the predictions of a mathematical model of strong immune selection upon a system where identical alleles may occupy different loci...
  7. pmc Role of selection in the emergence of lineages and the evolution of virulence in Neisseria meningitidis
    Caroline O Buckee
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom
    Proc Natl Acad Sci U S A 105:15082-7. 2008
    ..These findings have general implications for the emergence of lineage structure and virulence in recombining bacterial populations...
  8. pmc The effects of a partitioned var gene repertoire of Plasmodium falciparum on antigenic diversity and the acquisition of clinical immunity
    Mario Recker
    Department of Zoology, South Parks Road, OX1 3PS, Oxford, UK
    Malar J 7:18. 2008
    ..It has recently been shown that in spite of their extreme diversity, however, these genes fall into distinct groups according to chromosomal location or sequence similarity, and that recombination may be confined within these groups...
  9. pmc Antigenic variation in Plasmodium falciparum malaria involves a highly structured switching pattern
    Mario Recker
    Department of Zoology, University of Oxford, Oxford, United Kingdom
    PLoS Pathog 7:e1001306. 2011
    ..falciparum malaria as a balanced process of parasite-intrinsic switching and immune-mediated selection...
  10. pmc Opa protein repertoires of disease-causing and carried meningococci
    Martin J Callaghan
    Dept of Paediatrics, Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Churchill Hospital, Headington, Oxford OX3 9DU, United Kingdom
    J Clin Microbiol 46:3033-41. 2008
    ..Meningococcal Opa repertoire is strongly linked to MLST genotype irrespective of epidemiological sampling and therefore correlates with invasiveness. It is not, however, strongly associated with severity of meningococcal disease...
  11. pmc Pathogen selection drives nonoverlapping associations between HLA loci
    Bridget S Penman
    Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom
    Proc Natl Acad Sci U S A 110:19645-50. 2013
    ..In a wider coevolutionary context, our framework also shows that the inclusion of memory immunity can lead to robust cyclical dynamics across a range of host-pathogen systems. ..
  12. pmc Plasmodium falciparum var gene expression homogeneity as a marker of the host-parasite relationship under different levels of naturally acquired immunity to malaria
    George M Warimwe
    Pathogen, Vector and Human Biology Department, Kenya Medical Research Institute Wellcome Trust Research Programme, Kilifi, Kenya
    PLoS ONE 8:e70467. 2013
    ..We discuss this in relation to the potential role of host antibodies in promoting chronicity of infection and parasite survival through the low transmission season. ..
  13. pmc The emergence and maintenance of sickle cell hotspots in the Mediterranean
    Bridget S Penman
    Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
    Infect Genet Evol 12:1543-50. 2012
    ....