Research Topics
| Caroline O BuckeeSummaryAffiliation: University of Oxford Country: UK Publications
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Detail Information
Publications
The effects of host contact network structure on pathogen diversity and strain structureCaroline O F Buckee
Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom
Proc Natl Acad Sci U S A 101:10839-44. 2004..These results imply that host contact network structure plays a significant role in mediating the emergence of pathogen strain structure and dynamics...
Host community structure and the maintenance of pathogen diversityCaroline Buckee
Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
Proc Biol Sci 274:1715-21. 2007....
Modelling malaria population structure and its implications for controlCaroline O Buckee
Department of Zoology, University of Oxford, South Parks Road, Oxford, UK, OX1 3PS
Adv Exp Med Biol 673:112-26. 2010..Lastly, we discuss the current sequence data on parasite antigen genes that are important for the aquisition of immunity, and the results of a new analysis of P. falciparum population structure at the genomic level...
Long-term evolution of antigen repertoires among carried meningococciCaroline O Buckee
Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
Proc Biol Sci 277:1635-41. 2010..We contrast this antigenic structure with the overlapping but relatively stable combinations of the housekeeping genes observed among the same isolates, and use a novel network approach to visualize these relationships...
Inferring malaria parasite population structure from serological networksCaroline O Buckee
Department of Zoology, University of Oxford, Tinbergen Building, South Parks Road, Oxford OX1 3PS, UK
Proc Biol Sci 276:477-85. 2009..Our analysis suggests that different levels of immune selection occur within different groups of the same multigene family leading to mixed population structures...
The effect of immune selection on the structure of the meningococcal opa protein repertoireMartin J Callaghan
Department of Paediatrics, University of Oxford, Centre for Clinical Vaccinology and Tropical Medicine CCVTM, Churchill Hospital, Oxford, United Kingdom
PLoS Pathog 4:e1000020. 2008..These data are consistent with the predictions of a mathematical model of strong immune selection upon a system where identical alleles may occupy different loci...
Role of selection in the emergence of lineages and the evolution of virulence in Neisseria meningitidisCaroline O Buckee
Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom
Proc Natl Acad Sci U S A 105:15082-7. 2008..These findings have general implications for the emergence of lineage structure and virulence in recombining bacterial populations...
The effects of a partitioned var gene repertoire of Plasmodium falciparum on antigenic diversity and the acquisition of clinical immunityMario Recker
Department of Zoology, South Parks Road, OX1 3PS, Oxford, UK
Malar J 7:18. 2008..It has recently been shown that in spite of their extreme diversity, however, these genes fall into distinct groups according to chromosomal location or sequence similarity, and that recombination may be confined within these groups...
Antigenic variation in Plasmodium falciparum malaria involves a highly structured switching patternMario Recker
Department of Zoology, University of Oxford, Oxford, United Kingdom
PLoS Pathog 7:e1001306. 2011..falciparum malaria as a balanced process of parasite-intrinsic switching and immune-mediated selection...
Opa protein repertoires of disease-causing and carried meningococciMartin J Callaghan
Dept of Paediatrics, Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Churchill Hospital, Headington, Oxford OX3 9DU, United Kingdom
J Clin Microbiol 46:3033-41. 2008..Meningococcal Opa repertoire is strongly linked to MLST genotype irrespective of epidemiological sampling and therefore correlates with invasiveness. It is not, however, strongly associated with severity of meningococcal disease...
The emergence and maintenance of sickle cell hotspots in the MediterraneanBridget S Penman
Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
Infect Genet Evol 12:1543-50. 2012....
