J Bryant

Summary

Affiliation: University of Southampton
Country: UK

Publications

  1. pmc Clinical and cost-effectiveness of cardioprotection against the toxic effects of anthracyclines given to children with cancer: a systematic review
    J Bryant
    Southampton Health Technology Assessments Centre SHTAC, Wessex Institute for Health Research and Development, University of Southampton, Southampton SO16 7PX, UK
    Br J Cancer 96:226-30. 2007
  2. doi request reprint A systematic review of the clinical validity and clinical utility of DNA testing for hereditary haemochromatosis type 1 in at-risk populations
    J Bryant
    Southampton Health Technology Assessments Centre, Mailpoint 728, Boldrewood, University of Southampton, Southampton SO167PX, UK
    J Med Genet 45:513-8. 2008
  3. ncbi request reprint Use of cardiac markers to assess the toxic effects of anthracyclines given to children with cancer: a systematic review
    J Bryant
    Southampton Health Technology Assessments Centre, Wessex Institute for Health Research and Development, Mailpoint 728, Boldrewood, University of Southampton, Southampton SO16 7PX, United Kingdom
    Eur J Cancer 43:1959-66. 2007
  4. pmc Payment to healthcare professionals for patient recruitment to trials: a systematic review
    J Bryant
    Wessex Institute for Health Research and Development, Boldrewood, University of Southampton, Southampton SO16 7PX
    BMJ 331:1377-8. 2005
  5. ncbi request reprint Systematic review of the Sugarbaker procedure for pseudomyxoma peritonei
    J Bryant
    Southampton Health Technology Assessments Centre, Wessex Institute for Health Research and Development, University of Southampton, Southampton, UK
    Br J Surg 92:153-8. 2005
  6. doi request reprint The clinical effectiveness and cost-effectiveness of bortezomib and thalidomide in combination regimens with an alkylating agent and a corticosteroid for the first-line treatment of multiple myeloma: a systematic review and economic evaluation
    J Picot
    Southampton Health Technology Assessments Centre, Southampton, UK
    Health Technol Assess 15:1-204. 2011
  7. ncbi request reprint Cardioprotection against the toxic effects of anthracyclines given to children with cancer: a systematic review
    J Bryant
    Southampton Health Technology Assessments Centre, Wessex Institute for Health Research and Development, University of Southampton, UK
    Health Technol Assess 11:iii, ix-x, 1-84. 2007
  8. doi request reprint Diagnostic strategies using DNA testing for hereditary haemochromatosis in at-risk populations: a systematic review and economic evaluation
    J Bryant
    Southampton Health Technology Assessments Centre, Wessex Institute for Health Research and Development, University of Southampton, UK
    Health Technol Assess 13:iii, ix-xi, 1-126. 2009
  9. doi request reprint The safety and effectiveness of different methods of earwax removal: a systematic review and economic evaluation
    A J Clegg
    Southampton Health Technology Assessments Centre, University of Southampton, UK
    Health Technol Assess 14:1-192. 2010
  10. ncbi request reprint Clinical effectiveness and costs of the Sugarbaker procedure for the treatment of pseudomyxoma peritonei
    J Bryant
    Southampton Health Technology Assessments Centre, Wessex Institute for Health Research and Development, Southampton, UK
    Health Technol Assess 8:iii, 1-54. 2004

Collaborators

Detail Information

Publications29

  1. pmc Clinical and cost-effectiveness of cardioprotection against the toxic effects of anthracyclines given to children with cancer: a systematic review
    J Bryant
    Southampton Health Technology Assessments Centre SHTAC, Wessex Institute for Health Research and Development, University of Southampton, Southampton SO16 7PX, UK
    Br J Cancer 96:226-30. 2007
    ..Further long-term research, which includes relevant outcome measures, is needed to determine whether technologies influence the development of cardiac damage without limiting the antitumour efficacy of anthracyclines...
  2. doi request reprint A systematic review of the clinical validity and clinical utility of DNA testing for hereditary haemochromatosis type 1 in at-risk populations
    J Bryant
    Southampton Health Technology Assessments Centre, Mailpoint 728, Boldrewood, University of Southampton, Southampton SO167PX, UK
    J Med Genet 45:513-8. 2008
    ..To evaluate the clinical validity and clinical utility of DNA testing in people suspected of having hereditary haemochromatosis and in family members of those diagnosed with the disorder...
  3. ncbi request reprint Use of cardiac markers to assess the toxic effects of anthracyclines given to children with cancer: a systematic review
    J Bryant
    Southampton Health Technology Assessments Centre, Wessex Institute for Health Research and Development, Mailpoint 728, Boldrewood, University of Southampton, Southampton SO16 7PX, United Kingdom
    Eur J Cancer 43:1959-66. 2007
    ..To evaluate the effectiveness of cardiac markers to quantify anthracycline-induced cardiotoxicity in children with cancer...
  4. pmc Payment to healthcare professionals for patient recruitment to trials: a systematic review
    J Bryant
    Wessex Institute for Health Research and Development, Boldrewood, University of Southampton, Southampton SO16 7PX
    BMJ 331:1377-8. 2005
  5. ncbi request reprint Systematic review of the Sugarbaker procedure for pseudomyxoma peritonei
    J Bryant
    Southampton Health Technology Assessments Centre, Wessex Institute for Health Research and Development, University of Southampton, Southampton, UK
    Br J Surg 92:153-8. 2005
    ..The aim of this article is to assess the clinical effectiveness and costs of the Sugarbaker procedure for pseudomyxoma peritonei...
  6. doi request reprint The clinical effectiveness and cost-effectiveness of bortezomib and thalidomide in combination regimens with an alkylating agent and a corticosteroid for the first-line treatment of multiple myeloma: a systematic review and economic evaluation
    J Picot
    Southampton Health Technology Assessments Centre, Southampton, UK
    Health Technol Assess 15:1-204. 2011
    ..More recently, combination therapies have incorporated drugs such as thalidomide (Thalidomide CelgeneĀ®, Celgene) and bortezomib (VelcadeĀ®, Janssen-Cilag)...
  7. ncbi request reprint Cardioprotection against the toxic effects of anthracyclines given to children with cancer: a systematic review
    J Bryant
    Southampton Health Technology Assessments Centre, Wessex Institute for Health Research and Development, University of Southampton, UK
    Health Technol Assess 11:iii, ix-x, 1-84. 2007
    ..To evaluate the technologies used to reduce anthracycline-induced cardiotoxicity in children. Also to evaluate cardiac markers to quantify cardiotoxicity, and identify cost-effectiveness studies and future research priorities...
  8. doi request reprint Diagnostic strategies using DNA testing for hereditary haemochromatosis in at-risk populations: a systematic review and economic evaluation
    J Bryant
    Southampton Health Technology Assessments Centre, Wessex Institute for Health Research and Development, University of Southampton, UK
    Health Technol Assess 13:iii, ix-xi, 1-126. 2009
    ..To evaluate DNA testing for detecting hereditary haemochromatosis (HHC) in subgroups of patients suspected of having the disorder and in family members of those diagnosed with HHC...
  9. doi request reprint The safety and effectiveness of different methods of earwax removal: a systematic review and economic evaluation
    A J Clegg
    Southampton Health Technology Assessments Centre, University of Southampton, UK
    Health Technol Assess 14:1-192. 2010
    ..Current practice for earwax removal generally involves the use of a softening agent, followed by irrigation of the ear if required. However, the safety and benefits of the different methods of removal are not known for certain...
  10. ncbi request reprint Clinical effectiveness and costs of the Sugarbaker procedure for the treatment of pseudomyxoma peritonei
    J Bryant
    Southampton Health Technology Assessments Centre, Wessex Institute for Health Research and Development, Southampton, UK
    Health Technol Assess 8:iii, 1-54. 2004
    ..This systematic review examines the clinical and cost-effectiveness of the Sugarbaker procedure for treating pseudomyxoma peritonei (PMP) and the costs of the procedure in the UK...
  11. doi request reprint A decision analysis model for diagnostic strategies using DNA testing for hereditary haemochromatosis in at risk populations
    K Cooper
    Southampton Health Technology Assessments Centre, Boldrewood, University of Southampton, Southampton, SO16 7PX
    QJM 101:631-41. 2008
    ..New techniques for diagnosing hereditary haemochromatosis (HHC) have become available alongside traditional tests such as liver biopsy and serum iron studies...
  12. doi request reprint The clinical effectiveness and cost-effectiveness of long-term weight management schemes for adults: a systematic review
    E Loveman
    Southampton Health Technology Assessments Centre, UK
    Health Technol Assess 15:1-182. 2011
    ..To assess the long-term clinical effectiveness and cost-effectiveness of multicomponent weight management schemes for adults in terms of weight loss and maintenance of weight loss...
  13. doi request reprint Dasatinib, high-dose imatinib and nilotinib for the treatment of imatinib-resistant chronic myeloid leukaemia: a systematic review and economic evaluation
    E Loveman
    Southampton Health Technology Assessments Centre SHTAC, University of Southampton, Southampton, UK
    Health Technol Assess 16:iii-xiii, 1-137. 2012
    ....
  14. ncbi request reprint Payment to healthcare professionals for patient recruitment to trials: systematic review and qualitative study
    J Raftery
    Wessex Institute for Health Research and Development, University of Southampton, UK
    Health Technol Assess 12:1-128, iii. 2008
    ..To review UK guidelines regarding the use of financial incentives for healthcare professionals to become involved in clinical trials, and to survey perceptions and current practice...
  15. doi request reprint Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation
    A Takeda
    Southampton Health Technology Assessments Centre, Southampton, UK
    Health Technol Assess 14:1-209, iii-iv. 2010
    ....
  16. ncbi request reprint The clinical and cost-effectiveness of left ventricular assist devices for end-stage heart failure: a systematic review and economic evaluation
    A J Clegg
    Southampton Health Technology Assessments Centre, Wessex Institute for Health Research and Development, University of Southampton, UK
    Health Technol Assess 9:1-132, iii-iv. 2005
    ....
  17. ncbi request reprint The clinical and cost-effectiveness of implantable cardioverter defibrillators: a systematic review
    J Bryant
    Southampton Health Technology Assessments Centre, Wessex Institute for Health Research and Development, University of Southampton, UK
    Health Technol Assess 9:1-150, iii. 2005
    ..To consider the clinical effectiveness and cost-effectiveness of implantable cardioverter defibrillators (ICDs) for arrhythmias...
  18. doi request reprint Bortezomib for the treatment of multiple myeloma patients
    C Green
    Southampton Health Technology Assessments Centre, Wessex Institute for Health Research and Development, University of Southampton, UK
    Health Technol Assess 13:29-33. 2009
    ....
  19. ncbi request reprint Endocrinology trial design: adverse event reporting in randomised controlled trials of recombinant human GH in GH-deficient adults
    J Bryant
    Southampton Health Technology Assessment Centre, Wessex Institute for Health Research and Development, University of Southampton, Bassett Crescent East, UK
    J Endocrinol 175:545-52. 2002
    ..Therefore those conducting endocrinology trials in the future need to pay attention to the reporting of withdrawals due to adverse events and specific adverse events...
  20. pmc Implantable cardioverter-defibrillators in arrhythmias: a rapid and systematic review of effectiveness
    J Parkes
    University of Southampton, Southampton, UK
    Heart 87:438-42. 2002
    ..To review the effectiveness of implantable cardioverter-defibrillators (ICDs) in the management of risk factors for sudden cardiac death...
  21. doi request reprint Clinical effectiveness and cost-effectiveness of depth of anaesthesia monitoring (E-Entropy, Bispectral Index and Narcotrend): a systematic review and economic evaluation
    J Shepherd
    Southampton Health Technology Assessments Centre SHTAC, University of Southampton, Southampton, UK
    Health Technol Assess 17:1-264. 2013
    ..This may also prolong recovery times, potentially increasing health-care costs. If anaesthesia is too light, patients may not be fully unconscious and could be at risk of intraoperative awareness...
  22. ncbi request reprint Clinical effectiveness and cost-effectiveness of growth hormone in children: a systematic review and economic evaluation
    J Bryant
    Southampton Health Technology Assessments Centre, Wessex Institute for Health Research and Development, University of Southampton, Southampton SO16 7PX, UK
    Health Technol Assess 6:1-168. 2002
  23. doi request reprint Non-occupational postexposure prophylaxis for HIV: a systematic review
    J Bryant
    Southampton Health Technology Assessments Centre, Wessex Institute for Health Research and Development, University of Southampton, Southampton, UK
    Health Technol Assess 13:iii, ix-x, 1-60. 2009
    ..To review the evidence on the clinical effectiveness and cost-effectiveness of non-occupational postexposure prophylaxis (PEP) for HIV...
  24. ncbi request reprint Immunomodulatory drugs for multiple sclerosis: a systematic review of clinical and cost effectiveness
    A Clegg
    Southampton Health Technology Assessments Centre, Wessex Institute for Health Research and Development, University of Southampton, Biomedical Sciences Building, Bassett Crescent East, Southampton SO16 7PX, UK
    Expert Opin Pharmacother 2:623-39. 2001
    ..The inadequacies in the evidence of clinical and cost effectiveness on some immunomodulatory drugs for the treatment of people with MS necessitate further rigorous RCTs and comparative economic evaluations of different alternatives...
  25. pmc Systematic review of immunomodulatory drugs for the treatment of people with multiple sclerosis: Is there good quality evidence on effectiveness and cost?
    J Bryant
    Wessex Institute for Health Research and Development, University of Southampton, Biomedical Sciences Building Mailpoint 728, Bassett Crescent East, Southampton SO16 7PX, UK
    J Neurol Neurosurg Psychiatry 70:574-9. 2001
    ..To review the clinical effectiveness and costs of a range of disease modifying drugs in multiple sclerosis. Drugs included are azathioprine, cladribine, cyclophosphamide, intravenous immunoglobulin, methotrexate, and mitoxantrone...
  26. ncbi request reprint Clinical and cost-effectiveness of donepezil, rivastigmine and galantamine for Alzheimer's disease: a rapid and systematic review
    A Clegg
    Wessex Institute for Health Research and Development, University of Southampton, UK
    Health Technol Assess 5:1-137. 2001
    ..Statistically significant improvements in tests such as ADAS-cog (Alzheimer's Disease Assessment Scale cognitive subscale) may not be reflected in changes in daily life. (ABSTRACT TRUNCATED)..
  27. ncbi request reprint Clinical effectiveness and cost-effectiveness of growth hormone in adults in relation to impact on quality of life: a systematic review and economic evaluation
    J Bryant
    Southampton Health Technology Assessments Centre, Wessex Institute for Health Research and Development, University of Southampton, UK
    Health Technol Assess 6:1-106. 2002
  28. pmc Apolipoprotein E (ApoE), a novel heparin-binding protein inhibits the development of Kaposi's sarcoma-like lesions in BALB/c nu/nu mice
    P J Browning
    Laboratory of Tumor Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892
    J Exp Med 180:1949-54. 1994
    ..ApoE-3 also inhibited the formation of neoangiogenic lesions induced in BALB/c nu/nu mice by AIDS-KS cells. These findings represent a novel and potentially less toxic therapeutic approach for the treatment of AIDS-KS...
  29. pmc A study of familial hypercholesterolaemia in Iceland using RFLPs
    R Taylor
    Charing Cross Sunley Research Centre, Hammersmith, London
    J Med Genet 26:494-8. 1989
    ....