Research Topics
Genomes and Genes
Species | E J BrunnerSummaryAffiliation: University College London Country: UK Publications
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Detail Information
Publications
The association between father's social class and adult obesity is not explained by educational attainment and an unhealthy lifestyle in adulthoodAlexandros Heraclides
Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, UK
Eur J Epidemiol 23:573-9. 2008..To investigate the effect of father's social class on central and general obesity in adulthood. To test the role of educational attainment and adult health behaviours as mediators in this association...
Social epidemiology and Eastern WisdomEric Brunner
Department of Epidemiology and Public Health, University College London, London, United Kingdom
J Epidemiol 22:291-4. 2012..Exploring and debating commonalities and differences in the determinants of health in Oriental and Occidental cultures could offer fresh inspiration and insight for the next phase of social epidemiology in both regions...
Comparison of physical, public and human assets as determinants of socioeconomic inequalities in contraceptive use in Colombia - moving beyond the household wealth indexCatalina González
Department of Epidemiology and Public Health University College London, London, UK
Int J Equity Health 9:10. 2010..We tested the hypothesis that provision of Public capital compensated for low levels of Human capital...- Socioeconomic position and risk of short-term weight gain: prospective study of 14,619 middle-aged men and womenLisa R Purslow
MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
BMC Public Health 8:112. 2008..The association between socioeconomic position in middle age and risk of subsequent, short-term weight gain is unknown. We therefore assessed this association in a prospective population based cohort study in Norfolk, UK... - Fish, human health and marine ecosystem health: policies in collisionEric J Brunner
Department of Epidemiology and Public Health, University College London, London WC1E 7HB, UK
Int J Epidemiol 38:93-100. 2009..Health recommendations advocating increased fish consumption need to be placed in the context of the potential collapse of global marine capture fisheries... - Commentary: what is the best way to promote healthy eating?Eric Brunner
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Int J Epidemiol 35:415-7. 2006 
Biology and health inequalityEric Brunner
Departmentof Epidemiology and Public Health, University College London, London, United Kingdom
PLoS Biol 5:e267. 2007- Stress and the biology of inequalityE Brunner
Department of Epidemiology and Public Health, University College London
BMJ 314:1472-6. 1997..The biological effects of the psychosocial environment could explain health inequalities between relatively affluent groups... - Social inequality in walking speed in early old age in the Whitehall II studyEric Brunner
Department of Epidemiology and Public Health, University College London, UK
J Gerontol A Biol Sci Med Sci 64:1082-9. 2009..We investigated social inequalities in walking speed in early old age... - Dietary patterns and 15-y risks of major coronary events, diabetes, and mortalityEric J Brunner
Department of Epidemiology and Public Health, University College London, London, United Kingdom
Am J Clin Nutr 87:1414-21. 2008..Few studies have examined the long-term effect of habitual diet on risks of incident diabetes, coronary heart disease, and mortality... - Relation between blood glucose and coronary mortality over 33 years in the Whitehall StudyEric J Brunner
Department of Epidemiology and Public Health, University College London, UK
Diabetes Care 29:26-31. 2006..We examined the prospective relation of 2-h postload blood glucose (2hBG) with coronary and other major causes of mortality over 33 years... - Is the effect of work stress on cardiovascular mortality confounded by socioeconomic factors in the Valmet study?E J Brunner
International Centre for Health and Society, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
J Epidemiol Community Health 58:1019-20. 2004 - Arterial stiffness, physical function, and functional limitation: the Whitehall II StudyEric J Brunner
Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK
Hypertension 57:1003-9. 2011..The nature of the link between arterial stiffness and quality of life in older people merits attention... - What is an optimal diet? Relationship of macronutrient intake to obesity, glucose tolerance, lipoprotein cholesterol levels and the metabolic syndrome in the Whitehall II studyE J Brunner
International Centre for Health and Society, Department of Epidemiology and Public Health, University College, London, UK
Int J Obes Relat Metab Disord 25:45-53. 2001..Finally, we test the effect of macronutrient intake on the presence or absence of the metabolic syndrome... - Dietary assessment in Whitehall II: comparison of 7 d diet diary and food-frequency questionnaire and validity against biomarkersE Brunner
International Centre for Health and Society, Department of Epidemiology and Public Health, University College London Medical School, 1 19 Torrington Place, London WC1E 6BT, UK
Br J Nutr 86:405-14. 2001.... - Cost effectiveness of cardiovascular disease prevention strategies: a perspective on EU food based dietary guidelinesE Brunner
International Centre for Health and Society, Department of Epidemiology and Public Health, University College London Medical School, UK
Public Health Nutr 4:711-5. 2001..EU wide food based dietary guidelines are potentially the basis of large health gains in Europe, and cost-effectiveness studies tend to support their adoption... - Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome: nested case-control studyE J Brunner
International Centre for Health and Society, Department of Epidemiology and Public Health, University College London, England
Circulation 106:2659-65. 2002..We examine reversibility and the power of psychosocial and behavioral factors to explain the neuroendocrine adaptations that accompany MS... - Social and biological determinants of cognitive agingEric J Brunner
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WCIE 6BT, UK
Neurobiol Aging 26:17-20. 2005.... - Physical and cognitive function in midlife: reciprocal effects? A 5-year follow-up of the Whitehall II studyM Elovainio
International Institute for Society and Health, Department of Epidemiology and Public Health, UCL Medical School, London, UK
J Epidemiol Community Health 63:468-73. 2009..Whether cognitive function predicts physical function and whether physical function predicts cognitive function were assessed in middle-aged men and women... - Associations of C-reactive protein and interleukin-6 with cognitive symptoms of depression: 12-year follow-up of the Whitehall II studyD Gimeno
International Institute for Society and Health, Department of Epidemiology and Public Health, UCL Medical School, London, UK
Psychol Med 39:413-23. 2009..The present study sought to assess whether C-reactive protein and interleukin-6 predict cognitive symptoms of depression or whether these symptoms predict inflammatory markers... - Cumulative exposure to high-strain and active jobs as predictors of cognitive function: the Whitehall II studyM Elovainio
University College London, London, UK
Occup Environ Med 66:32-7. 2009..We tested associations between high-strain and active jobs and cognitive function in middle-aged men and women... - Biological and behavioural explanations of social inequalities in coronary heart disease: the Whitehall II studyM G Marmot
Department of Epidemiology and Public Health, University College London, London, WC1E 6BT, UK
Diabetologia 51:1980-8. 2008..We determined the degree to which metabolic syndrome components, inflammation and health behaviours account for the social gradient in CHD... - Dietary glycemic index and glycemic load are associated with high-density-lipoprotein cholesterol at baseline but not with increased risk of diabetes in the Whitehall II studyAnnhild Mosdøl
International Institute for Society and Health, Department of Epidemiology and Public Health, University College London, United Kingdom
Am J Clin Nutr 86:988-94. 2007..Findings of the effect of dietary glycemic index (GI) and glycemic load (GL) on the risk of incident diabetes are inconsistent... - Changes in C-reactive protein levels before type 2 diabetes and cardiovascular death: the Whitehall II studyA G Tabák
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6 BT, UK
Eur J Endocrinol 163:89-95. 2010..This study describes CRP trajectories prior to type 2 diabetes onset and fatal CVD... - Do the Joint British Society (JBS2) guidelines on prevention of cardiovascular disease with respect to plasma glucose improve risk stratification in the general population? Prospective cohort studyE J Brunner
Department of Epidemiology and Public Health, University College London, London, UK
Diabet Med 27:550-5. 2010.... - APOE polymorphism, socioeconomic status and cognitive function in mid-life--the Whitehall II longitudinal studyJ H Zhao
Dept of Epidemiology and Public Health, International Centre for Health and Society, 1 19 Torrington Place, London WC1E 6BT, UK
Soc Psychiatry Psychiatr Epidemiol 40:557-63. 2005.... - Association between IL6 gene variants -174G>C and -572G>C and serum IL-6 levels: interactions with social position in the Whitehall II cohortSaskia C Sanderson
Department of Epidemiology and Public Health Whitehall II, 1 19 Torrington Place, University College London, London WC1E 6BT, UK
Atherosclerosis 204:459-64. 2009..To examine the impact of -174G>C and -572G>C variants in the promoter region of the IL6 gene, and their interactions with social position, on interleukin-6 (IL-6) levels in the Whitehall II cohort... - Incidence and prognosis of angina pectoris in South Asians and Whites: 18 years of follow-up over seven phases in the Whitehall-II prospective cohort studyM J S Zaman
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
J Public Health (Oxf) 33:430-8. 2011..This study assessed cumulative incidence of chest pain in South Asians and Whites, and prognosis of chest pain... - Predictors of early retirement in British civil servantsG Mein
Department of Epidemiology and Public Health, University College London, UK
Age Ageing 29:529-36. 2000..The Whitehall II study provides an opportunity to examine the predictors of early retirement in one of the largest employers in the United Kingdom... - Performance of existing risk scores in screening for undiagnosed diabetes: an external validation studyD R Witte
Department of Epidemiology and Public Health, University College London, London, UK
Diabet Med 27:46-53. 2010..To compare the performance of nine published strategies for the selection of individuals prior to screening for undiagnosed diabetes... - Prospective effect of job strain on general and central obesity in the Whitehall II StudyEric J Brunner
Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, England
Am J Epidemiol 165:828-37. 2007..This study provides prospective, population-based evidence that chronic work stress predicts general and central obesity... - Education attenuates the association between dietary patterns and cognitionTasnime N Akbaraly
Department of Epidemiology and Public Health, University College London, London, UK
Dement Geriatr Cogn Disord 27:147-54. 2009..As individual food items are not consumed in isolation, we examined the association between dietary patterns and cognitive function, with special attention to the role of education in this association... - Socioeconomic gradient in body size and obesity among women: the role of dietary restraint, disinhibition and hunger in the Whitehall II studyJ Dykes
Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, UK
Int J Obes Relat Metab Disord 28:262-8. 2004..Hunger and disinhibition explain a moderate amount of the gradient in body size across employment grade and may be useful concepts for future work on the socio-economic gradient in obesity and overweight... - Low serum adiponectin predicts 10-year risk of type 2 diabetes and HbA1c independently of obesity, lipids, and inflammation: Whitehall II studyA G Tabák
Department of Epidemiology and Public Health, University College London, London WCE1 6BT, UK
Horm Metab Res 41:626-9. 2009..05). The observed robust, prospective associations support that adiponectin is an independent predictor of diabetes and the degree of glycaemic impairment... - Methodological problems in genetic association studies of longevity--the apolipoprotein E gene as an exampleSarah J Lewis
International Centre for Health and Society, Department of Epidemiology and Public Health, University College London, London, UK
Int J Epidemiol 33:962-70. 2004..Such studies are based on two assumptions; (a) initial relative allele frequencies in the different age cohorts are similar, and (b) the risk of mortality conferred by genotypes does not depend on year of birth... - Dietary pattern and depressive symptoms in middle ageTasnime N Akbaraly
Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK
Br J Psychiatry 195:408-13. 2009..Studies of diet and depression have focused primarily on individual nutrients... - Socio-demographic influences on trends of fish consumption during later adult life in the Whitehall II studyTasnime N Akbaraly
Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK
Br J Nutr 100:1116-27. 2008..Such information is valuable for food policies that seek to promote health equity... - Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort studyPhilippa J Talmud
Centre of Cardiovascular Genetics, Department of Medicine, University College London, London WC1E 6JF
BMJ 340:b4838. 2010.... - No APOEepsilon4 effect on coronary heart disease risk in a cohort with low smoking prevalence: the Whitehall II studyPhilippa J Talmud
British Heart Foundation Laboratories, Department of Medicine, Centre for Cardiovascular Genetics, Rayne Building, University College London, 5 University Street, London WC1E 6JF, UK
Atherosclerosis 177:105-12. 2004..This supports the context dependency of the epsilon4 risk effect, but the low smoking incidence in the Whitehall men reduced our ability to examine a smoking:genotype interaction... - Deprivation and the development of obesity a multilevel, longitudinal study in EnglandMai Stafford
Department of Epidemiology and Public Health, University College London, United Kingdom
Am J Prev Med 39:130-9. 2010..Evidence indicates that the rising trend in overweight and obesity may be stronger for people from more socioeconomically advantaged backgrounds... - Association between change in body composition and change in inflammatory markers: an 11-year follow-up in the Whitehall II StudyEleonor I Fransson
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, United Kingdom
J Clin Endocrinol Metab 95:5370-4. 2010..Obesity is associated with low-grade inflammation, but the long-term effects of weight change on inflammation are unknown... - Decline in low-density lipoprotein cholesterol concentration: lipid-lowering drugs, diet, or physical activity? Evidence from the Whitehall II studyKim Bouillon
Department of Epidemiology and Public Health, University College London, London, UK
Heart 97:923-30. 2011..To examine the association of lipid-lowering drugs, change in diet and physical activity with a decline in low-density lipoprotein (LDL) cholesterol in middle age... - Prospective study of physical activity and physical function in early old ageMelvyn M Hillsdon
International Centre for Health and Society, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, England
Am J Prev Med 28:245-50. 2005..In this study, we test the hypothesis that physical activity earlier in the life course preserves high physical function over an extended period of time, before the onset of major age-related declines in physical function... - Hyperglycemia, type 2 diabetes, and depressive symptoms: the British Whitehall II studyMika Kivimaki
Department of Epidemiology and Public Health, University College London, London, UK
Diabetes Care 32:1867-9. 2009..To examine the recent suggestion that impaired fasting glucose may protect against depression, whereas a diagnosis of diabetes might then result in depression... - Inflammation, insulin resistance, and diabetes--Mendelian randomization using CRP haplotypes points upstreamEric J Brunner
Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, United Kingdom
PLoS Med 5:e155. 2008..Our objective was to examine the nature of the association between CRP phenotype and diabetes development using CRP haplotypes as instrumental variables... - Adult socioeconomic position, C-reactive protein and interleukin-6 in the Whitehall II prospective studyDavid Gimeno
International Institute for Society and Health, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London, WC1E 6BT, UK
Eur J Epidemiol 22:675-83. 2007..Thus, the question of whether socioeconomic differences in CRP and IL-6 change over time remains unanswered. We examined the relationship between SEP and changes over 12 years in CRP and IL-6... - Estimated prevalence and predictors of vitamin C deficiency within UK's low-income populationAnnhild Mosdøl
Department of Epidemiology and Public Health, University College London, UK
J Public Health (Oxf) 30:456-60. 2008..The Low Income Diet and Nutrition Survey (2003-05) of a representative sample of the low-income/materially deprived UK population included a plasma vitamin C measurement... - Prospective study of coffee and tea consumption in relation to risk of type 2 diabetes mellitus among men and women: the Whitehall II studyMark Hamer
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Br J Nutr 100:1046-53. 2008..The limited range of exposure and beverage consumption according to socio-economic class may explain these conflicting findings... - Association between metabolic syndrome and depressive symptoms in middle-aged adults: results from the Whitehall II studyTasnime N Akbaraly
Department of Epidemiology and Public Health, University College London, London, UK
Diabetes Care 32:499-504. 2009..We examined whether the metabolic syndrome is associated with the onset of depressive symptoms in a cohort of middle-aged British civil servants... - Trajectories of glycaemia, insulin sensitivity, and insulin secretion before diagnosis of type 2 diabetes: an analysis from the Whitehall II studyAdam G Tabak
Department of Epidemiology and Public Health, University College London, London, UK
Lancet 373:2215-21. 2009..We aimed to characterise trajectories of fasting and postload glucose, insulin sensitivity, and insulin secretion in individuals who develop type 2 diabetes... - Psychosocial stress at work doubles the risk of type 2 diabetes in middle-aged women: evidence from the Whitehall II studyAlexandros Heraclides
Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, UK
Diabetes Care 32:2230-5. 2009..To investigate the effect of psychosocial stress at work on risk of type 2 diabetes, adjusting for conventional risk factors, among a sample of British, white-collar, middle-aged men and women... - Organizational justice and sleeping problems: The Whitehall II studyMarko Elovainio
Department of Epidemiology and Public Health, UCL Medical School, London, England, UK
Psychosom Med 71:334-40. 2009..To test the hypothesis that organizational injustice contributes to sleeping problems. Poor sleep quality can be a marker of prolonged emotional stress and has been shown to have serious effects on the immune system and metabolism... - Gender-specific associations of short sleep duration with prevalent and incident hypertension: the Whitehall II StudyFrancesco P Cappuccio
Clinical Sciences Research Institute, Warwick Medical School, Coventry, United Kingdom
Hypertension 50:693-700. 2007..42 [95% CI: 0.94 to 2.16]; odds ratio: 1.31 [95% CI: 0.65 to 2.63], respectively). Sleep deprivation may produce detrimental cardiovascular effects among women... - Cross-sectional versus prospective associations of sleep duration with changes in relative weight and body fat distribution: the Whitehall II StudySaverio Stranges
Cardiovascular Medicine and Epidemiology Group, Clinical Sciences Research Institute, University of Warwick Medical School, Coventry, England
Am J Epidemiol 167:321-9. 2008..23, 1.12), nor with the incidence of obesity (odds ratio(adjusted) = 1.05, 95% CI: 0.60, 1.82). There is no temporal relation between short duration of sleep and future changes in measures of body weight and central adiposity... - Dietary patterns, insulin resistance, and incidence of type 2 diabetes in the Whitehall II StudySarah A McNaughton
School of Exercise and Nutrition Sciences, Deakin University, Melbourne, Australia
Diabetes Care 31:1343-8. 2008..The aim of this study was to identify a dietary pattern associated with insulin resistance and investigate whether this pattern was prospectively associated with type 2 diabetes...