Research Topics
| Angela B BrueggemannSummaryAffiliation: University of Oxford Country: UK Publications
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Detail Information
Publications
Chloramphenicol treatment for acute infective conjunctivitis in children in primary care: a randomised double-blind placebo-controlled trialPeter W Rose
Department of Primary Health Care, University of Oxford, Oxford, UK
Lancet 366:37-43. 2005..We undertook a randomised double-blind trial to compare the effectiveness of chloramphenicol eye drops with placebo in children with infective conjunctivitis in primary care...
Antibiotic resistance mechanisms among pediatric respiratory and enteric pathogens: A current updateAngela B Brueggemann
Department of Zoology, University of Oxford, Oxford, UK
Pediatr Infect Dis J 25:969-73. 2006..The most recently published literature is used wherever possible, and the reader is encouraged to explore specific topics of interest further by reviewing the referenced literature...
Invasive pneumococcal disease: epidemiology in children and adults prior to implementation of the conjugate vaccine in the Oxfordshire region, EnglandDona Foster
Nuffield Department of Clinical Laboratory Science, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK
J Med Microbiol 57:480-7. 2008..The data provide a baseline against which the impact of the pneumococcal conjugate vaccine introduced in the UK in 2006 could be measured...
Vaccine escape recombinants emerge after pneumococcal vaccination in the United StatesAngela B Brueggemann
Department of Zoology, University of Oxford, Oxford, United Kingdom
PLoS Pathog 3:e168. 2007..Vaccine escape by genetic recombination at the capsular locus has the potential to reduce PCV7 effectiveness in the longer term...
Respiratory infections for which general practitioners consider prescribing an antibiotic: a prospective studyAnthony Harnden
Department of Primary Health Care, University of Oxford, Oxford, UK
Arch Dis Child 92:594-7. 2007..To determine the viral aetiology of respiratory infections in children presenting to primary care with "more than a simple cold"...
Temporal and geographic stability of the serogroup-specific invasive disease potential of Streptococcus pneumoniae in childrenAngela B Brueggemann
Academic Department of Microbiology and Infectious Disease, University of Oxford, Oxford, United Kingdom
J Infect Dis 190:1203-11. 2004..There was no evidence of any temporal change or major geographical differences in serotype- or serogroup-specific invasive disease potential...
Geographic distribution and clonal diversity of Streptococcus pneumoniae serotype 1 isolatesAngela B Brueggemann
Academic Department of Microbiology and Infectious Disease, University of Oxford, Oxford, United Kingdom
J Clin Microbiol 41:4966-70. 2003..There was no clear association between the presence of individual clones within a country and the prevalence of serotype 1 disease...
Molecular typing methods for outbreak detection and surveillance of invasive disease caused by Neisseria meningitidis, Haemophilus influenzae and Streptococcus pneumoniae, a reviewOdile B Harrison
Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
Microbiology 157:2181-95. 2011..meningitidis and which could be more widely deployed in clinical laboratories for S. pneumoniae and H. influenzae...
Clonal relationships between invasive and carriage Streptococcus pneumoniae and serotype- and clone-specific differences in invasive disease potentialAngela B Brueggemann
Academic Department of Microbiology and Infectious Disease, John Radcliffe Hospital and Department of Public Health and Primary Care, University of Oxford, Oxford, United Kingdom
J Infect Dis 187:1424-32. 2003....
Whooping cough in school age children with persistent cough: prospective cohort study in primary careAnthony Harnden
Department of Primary Health Care, University of Oxford, Oxford OX3 7LF
BMJ 333:174-7. 2006..To estimate the proportion of school age children with a persistent cough who have evidence of a recent Bordetella pertussis infection...
Pneumococcal genome sequencing tracks a vaccine escape variant formed through a multi-fragment recombination eventTanya Golubchik
Department of Statistics, University of Oxford, UK
Nat Genet 44:352-5. 2012....
Fluoroquinolone resistance in Streptococcus pneumoniae in United States since 1994-1995Angela B Brueggemann
Department of Zoology, University of Oxford, Oxford, United Kingdom
Antimicrob Agents Chemother 46:680-8. 2002....
Effect of antibiotic prescribing on antibiotic resistance in individual children in primary care: prospective cohort studyAngela Chung
Department of Primary Health Care, NIHR School of Primary Care Research, University of Oxford, Oxford OX3 7LF
BMJ 335:429. 2007..To assess the effect of community prescribing of an antibiotic for acute respiratory infection on the prevalence of antibiotic resistant bacteria in an individual child...
Presence of nonhemolytic pneumolysin in serotypes of Streptococcus pneumoniae associated with disease outbreaksJohanna M C Jefferies
Institute of Biomedical and Life Sciences, Division of Infection and Immunity, University of Glasgow, Glasgow, United Kingdom
J Infect Dis 196:936-44. 2007..Serotype 1 and 8 pneumococci are known to be associated with outbreaks of invasive disease. The nonhemolytic pneumolysin allele is therefore associated with the dominant clones of outbreak-associated serotypes of S. pneumoniae...
Stability of serotypes during nasopharyngeal carriage of Streptococcus pneumoniaeEmma Meats
Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, St. Mary's Hospital Campus, London W2 1PG, United Kingdom
J Clin Microbiol 41:386-92. 2003..There was therefore no evidence in this study for any change of serotype due to recombinational replacements at the capsular locus among the pneumococci carried within the nasopharynges of the children...
Population snapshot of emergent Streptococcus pneumoniae serotype 19A in the United States, 2005Matthew R Moore
Respiratory Diseases Branch, Centers for Disease Control and Prevention, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA
J Infect Dis 197:1016-27. 2008..To understand this increase, we characterized serotype 19A isolates recovered during 2005...
Molecular typing of pneumococci causing parapneumonic empyema in Spanish children using multilocus sequence typing directly on pleural fluid samplesIgnacio Obando
Pediatr Infect Dis J 25:962-3. 2006
Characterization of German penicillin non-susceptible serotype 23F pneumococci using multilocus sequence typingRalf Rene Reinert
Institute of Medical Microbiology, National Reference Center for Streptococci, University Hospital, D 52057 Aachen, Germany
J Med Microbiol 52:981-7. 2003..4 %) have sequence types that have not been reported to date from other countries (STs 353-362). The major penicillin-resistant clones are present in Germany, a country with relatively low levels of beta-lactam resistance...
Liquid ventilation with perflubron in the treatment of rats with pneumococcal pneumoniaEric W Dickson
Department of Physiology, University of Massachusetts Medical Center, Worcester, MA 01655, USA
Crit Care Med 30:393-5. 2002..To determine the efficacy of liquid ventilation using a medical-grade perfluorocarbon (perflubron) combined with parenteral or intratracheal antibiotics in a rat model of pneumonia...
