Research Topics
| Kimberley D BruceSummaryAffiliation: University of Southampton Country: UK Publications
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Detail Information
Publications
The housekeeping gene YWHAZ remains stable in a model of developmentally primed non-alcoholic fatty liver diseaseKimberley D Bruce
Human Development and Health, Institute of Developmental Sciences, University of Southampton Faculty of Medicine, Southampton, UK
Liver Int 32:1315-21. 2012..However, there is little existing data to show the effects of NAFLD on HKG expression...
Maternal high-fat feeding primes steatohepatitis in adult mice offspring, involving mitochondrial dysfunction and altered lipogenesis gene expressionKimberley D Bruce
Institute of Developmental Sciences, University of Southampton, Southampton General Hospital, Southampton, UK
Hepatology 50:1796-808. 2009..CONCLUSION: Maternal fat intake contributes toward the NAFLD progression in adult offspring, which is mediated through impaired hepatic mitochondrial metabolism and up-regulated hepatic lipogenesis...
The developmental origins, mechanisms, and implications of metabolic syndromeKimberley D Bruce
Developmental Origins of Health and Disease Division, Institute of Developmental Sciences, University of Southampton School of Medicine, Southampton General Hospital, Southampton, UK
J Nutr 140:648-52. 2010..A continued and greater understanding of these mechanisms will eventually allow specific interventions, with a favorable impact on the global incidence of cardiovascular disease and type 2 diabetes in the future...
Epigenetic priming of the metabolic syndromeKimberley D Bruce
Developmental Origins of Health and Disease Division, Institute of Developmental Sciences, University of Southampton School of Medicine, Southampton, UK
Toxicol Mech Methods 21:353-61. 2011....
Interaction between maternal and offspring diet to impair vascular function and oxidative balance in high fat fed male miceChristopher Torrens
Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
PLoS ONE 7:e50671. 2012..To determine the impact of maternal and post-weaning consumption of a high fat diet on endothelium-dependent vasorelaxation and redox regulation in adult male mouse offspring...
Metabolic disturbances in non-alcoholic fatty liver diseaseChristopher D Byrne
Endocrinology and Metabolism Unit, Institute for Developmental Sciences, University of Southampton and Southampton University Hospitals Trust, Southampton General Hospital, Southampton SO16 6YD, UK
Clin Sci (Lond) 116:539-64. 2009....
The role of the circadian clock system in nutrition and metabolismFelino R Cagampang
Institute of Developmental Sciences, Faculty of Medicine, University of Southampton, MP887 Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK
Br J Nutr 108:381-92. 2012..Thus, alterations in environmental cues could disrupt normal clock function, which may have profound effects on the health and well-being of an individual...
