Sara J Brown

Summary

Affiliation: University of Newcastle
Country: UK

Publications

  1. ncbi Pseudoxanthoma elasticum: biopsy of clinically normal skin in the investigation of patients with angioid streaks
    S J Brown
    Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Br J Dermatol 157:748-51. 2007
  2. doi Filaggrin null mutations and childhood atopic eczema: a population-based case-control study
    Sara J Brown
    Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom
    J Allergy Clin Immunol 121:940-46.e3. 2008
  3. doi Atopic eczema and the filaggrin story
    Sara J Brown
    Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Semin Cutan Med Surg 27:128-37. 2008
  4. doi Eczema genetics: current state of knowledge and future goals
    Sara J Brown
    Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    J Invest Dermatol 129:543-52. 2009
  5. pmc Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of eczema: further delineation of the skin phenotype in a prospective epidemiological study of 792 school children
    S J Brown
    Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Br J Dermatol 161:884-9. 2009
  6. ncbi Case 3. Scarring from previous acne vulgaris. Basal cell carcinoma (BCC)
    S J Brown
    Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Clin Exp Dermatol 27:82-3. 2002
  7. ncbi The management of skin malignancy: to what extent should we rely on clinical diagnosis?
    S J Brown
    Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Br J Dermatol 155:100-3. 2006
  8. ncbi Subcorneal pustular dermatosis in association with chronic lymphocytic leukaemia
    Sara J Brown
    Acta Derm Venereol 83:306-7. 2003
  9. ncbi Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema
    Sara J Brown
    J Invest Dermatol 128:1591-4. 2008

Detail Information

Publications9

  1. ncbi Pseudoxanthoma elasticum: biopsy of clinically normal skin in the investigation of patients with angioid streaks
    S J Brown
    Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Br J Dermatol 157:748-51. 2007
    ..Biopsy of clinically normal skin or scar tissue in patients with angioid streaks may show the histological features of PXE...
  2. doi Filaggrin null mutations and childhood atopic eczema: a population-based case-control study
    Sara J Brown
    Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom
    J Allergy Clin Immunol 121:940-46.e3. 2008
    ..Null mutations within the filaggrin gene (FLG) are associated with moderate-to-severe atopic eczema; their role in mild-to-moderate eczema in the general population is unknown...
  3. doi Atopic eczema and the filaggrin story
    Sara J Brown
    Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Semin Cutan Med Surg 27:128-37. 2008
    ..Further research is needed to clarify the precise role of filaggrin in skin and systemic atopic disease, to pave the way for novel therapeutic interventions...
  4. doi Eczema genetics: current state of knowledge and future goals
    Sara J Brown
    Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    J Invest Dermatol 129:543-52. 2009
    ..Knowledge of genetic factors in eczema may translate into a clearer understanding of pathogenic mechanisms and hence more focused therapeutic strategies, but this remains at present a distant possibility...
  5. pmc Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of eczema: further delineation of the skin phenotype in a prospective epidemiological study of 792 school children
    S J Brown
    Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Br J Dermatol 161:884-9. 2009
    ..Null mutations within the filaggrin gene (FLG) cause ichthyosis vulgaris and are associated with atopic eczema. However, the dermatological features of filaggrin haploinsufficiency have not been clearly defined...
  6. ncbi Case 3. Scarring from previous acne vulgaris. Basal cell carcinoma (BCC)
    S J Brown
    Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Clin Exp Dermatol 27:82-3. 2002
  7. ncbi The management of skin malignancy: to what extent should we rely on clinical diagnosis?
    S J Brown
    Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Br J Dermatol 155:100-3. 2006
    ..Cutaneous malignancy forms a major part of the dermatologist's workload. Clinical diagnosis is an important factor in facilitating the urgent excision of squamous cell carcinomas (SCC) and malignant melanomas...
  8. ncbi Subcorneal pustular dermatosis in association with chronic lymphocytic leukaemia
    Sara J Brown
    Acta Derm Venereol 83:306-7. 2003
  9. ncbi Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema
    Sara J Brown
    J Invest Dermatol 128:1591-4. 2008