Martin M Brown

Summary

Affiliation: University College London
Country: UK

Publications

  1. doi request reprint Long-term outcomes after stenting versus endarterectomy for treatment of symptomatic carotid stenosis: the International Carotid Stenting Study (ICSS) randomised trial
    Leo H Bonati
    Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, University College London, London, UK Department of Neurology and Stroke Unit, University Hospital Basel, Basel University, Basel, Switzerland
    Lancet 385:529-38. 2015
  2. ncbi request reprint Carotid artery: overview on current trials - selecting the low-risk patient
    K R Czuriga-Kovács
    Department of Brain Repair and Rehabilitation, Institute of Neurology, University College London, Queen Square, London, UK
    J Cardiovasc Surg (Torino) 56:177-88. 2015
  3. pmc Incidence, impact, and predictors of cranial nerve palsy and haematoma following carotid endarterectomy in the international carotid stenting study
    D Doig
    Institute of Neurology, University College London, London, UK
    Eur J Vasc Endovasc Surg 48:498-504. 2014
  4. pmc Ipsilateral foetal-type posterior cerebral artery is associated with cognitive decline after carotid revascularisation
    Aysun Altinbas
    Utrecht Stroke Center, Departments of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    BMC Neurol 14:84. 2014
  5. doi request reprint Percutaneous transluminal balloon angioplasty and stenting for carotid artery stenosis
    Leo H Bonati
    Department ofNeurology, UniversityHospital Basel, Basel, Switzerland
    Cochrane Database Syst Rev 9:CD000515. 2012
  6. doi request reprint Carotid stenting versus endarterectomy
    David Doig
    Institute of Neurology, University College London, London WC1N 3BG, United Kingdom
    Annu Rev Med 63:259-76. 2012
  7. doi request reprint Predictors of acute and persisting ischemic brain lesions in patients randomized to carotid stenting or endarterectomy
    Ayda Rostamzadeh
    From the Department of Neurology and Stroke Unit A R, P A L, S T E, L H B, Clinical Trial Unit T Z, University Hospital Basel, Basel, Switzerland Department of Radiology L M J, W P Th M M, Department of Neurology, Rudolf Magnus Institute of Neuroscience L J K, H B v d W, University Medical Center Utrecht, Utrecht, The Netherlands Department of Neurology, Academic Medical Center Amsterdam, Amsterdam, The Netherlands P J N Department of Radiology, Freeman Hospital, Newcastle upon Tyne, United Kingdom S M and Department of Brain Repair and Rehabilitation, University College London Institute of Neurology, Queen Square, London, United Kingdom M M B, L H B
    Stroke 45:591-4. 2014
  8. pmc Long-term risk of carotid restenosis in patients randomly assigned to endovascular treatment or endarterectomy in the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS): long-term follow-up of a randomised trial
    Leo H Bonati
    Stroke Research Group, UCL Institute of Neurology, University College London, Queen Square, London, UK
    Lancet Neurol 8:908-17. 2009
  9. pmc Effect of white-matter lesions on the risk of periprocedural stroke after carotid artery stenting versus endarterectomy in the International Carotid Stenting Study (ICSS): a prespecified analysis of data from a randomised trial
    Jörg Ederle
    Stroke Research Group, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, Queen Square, London, UK
    Lancet Neurol 12:866-72. 2013
  10. doi request reprint Long-term outcome of endovascular treatment versus medical care for carotid artery stenosis in patients not suitable for surgery and randomised in the Carotid and Vertebral Artery Transluminal Angioplasty study (CAVATAS)
    Jörg Ederle
    Stroke Research Group, UCL Institute of Neurology, London, UK
    Cerebrovasc Dis 28:1-7. 2009

Detail Information

Publications38

  1. doi request reprint Long-term outcomes after stenting versus endarterectomy for treatment of symptomatic carotid stenosis: the International Carotid Stenting Study (ICSS) randomised trial
    Leo H Bonati
    Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, University College London, London, UK Department of Neurology and Stroke Unit, University Hospital Basel, Basel University, Basel, Switzerland
    Lancet 385:529-38. 2015
    ..Stenting is an alternative to endarterectomy for treatment of carotid artery stenosis, but long-term efficacy is uncertain. We report long-term data from the randomised International Carotid Stenting Study comparison of these treatments...
  2. ncbi request reprint Carotid artery: overview on current trials - selecting the low-risk patient
    K R Czuriga-Kovács
    Department of Brain Repair and Rehabilitation, Institute of Neurology, University College London, Queen Square, London, UK
    J Cardiovasc Surg (Torino) 56:177-88. 2015
    ....
  3. pmc Incidence, impact, and predictors of cranial nerve palsy and haematoma following carotid endarterectomy in the international carotid stenting study
    D Doig
    Institute of Neurology, University College London, London, UK
    Eur J Vasc Endovasc Surg 48:498-504. 2014
    ....
  4. pmc Ipsilateral foetal-type posterior cerebral artery is associated with cognitive decline after carotid revascularisation
    Aysun Altinbas
    Utrecht Stroke Center, Departments of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    BMC Neurol 14:84. 2014
    ..We compared the effects of carotid revascularisation on cognition between patients with a foetal-type and those with a normal posterior cerebral artery...
  5. doi request reprint Percutaneous transluminal balloon angioplasty and stenting for carotid artery stenosis
    Leo H Bonati
    Department ofNeurology, UniversityHospital Basel, Basel, Switzerland
    Cochrane Database Syst Rev 9:CD000515. 2012
    ..This review updates a previous version first published in 1997 and subsequently updated in 2004 and 2007...
  6. doi request reprint Carotid stenting versus endarterectomy
    David Doig
    Institute of Neurology, University College London, London WC1N 3BG, United Kingdom
    Annu Rev Med 63:259-76. 2012
    ....
  7. doi request reprint Predictors of acute and persisting ischemic brain lesions in patients randomized to carotid stenting or endarterectomy
    Ayda Rostamzadeh
    From the Department of Neurology and Stroke Unit A R, P A L, S T E, L H B, Clinical Trial Unit T Z, University Hospital Basel, Basel, Switzerland Department of Radiology L M J, W P Th M M, Department of Neurology, Rudolf Magnus Institute of Neuroscience L J K, H B v d W, University Medical Center Utrecht, Utrecht, The Netherlands Department of Neurology, Academic Medical Center Amsterdam, Amsterdam, The Netherlands P J N Department of Radiology, Freeman Hospital, Newcastle upon Tyne, United Kingdom S M and Department of Brain Repair and Rehabilitation, University College London Institute of Neurology, Queen Square, London, United Kingdom M M B, L H B
    Stroke 45:591-4. 2014
    ..We investigated predictors for acute and persisting periprocedural ischemic brain lesions among patients with symptomatic carotid stenosis randomized to stenting or endarterectomy in the International Carotid Stenting Study...
  8. pmc Long-term risk of carotid restenosis in patients randomly assigned to endovascular treatment or endarterectomy in the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS): long-term follow-up of a randomised trial
    Leo H Bonati
    Stroke Research Group, UCL Institute of Neurology, University College London, Queen Square, London, UK
    Lancet Neurol 8:908-17. 2009
    ..We aimed to investigate the long-term risks of restenosis in patients included in CAVATAS...
  9. pmc Effect of white-matter lesions on the risk of periprocedural stroke after carotid artery stenting versus endarterectomy in the International Carotid Stenting Study (ICSS): a prespecified analysis of data from a randomised trial
    Jörg Ederle
    Stroke Research Group, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, Queen Square, London, UK
    Lancet Neurol 12:866-72. 2013
    ..We assessed whether white-matter lesions affect the perioperative risk of stroke in patients treated with carotid artery stenting versus carotid endarterectomy...
  10. doi request reprint Long-term outcome of endovascular treatment versus medical care for carotid artery stenosis in patients not suitable for surgery and randomised in the Carotid and Vertebral Artery Transluminal Angioplasty study (CAVATAS)
    Jörg Ederle
    Stroke Research Group, UCL Institute of Neurology, London, UK
    Cerebrovasc Dis 28:1-7. 2009
    ..The Carotid and Vertebral Artery Transluminal Angioplasty study contained a trial comparing medical and endovascular treatment in patients not suitable for surgery...
  11. ncbi request reprint Safety and efficacy of endovascular treatment of carotid artery stenosis compared with carotid endarterectomy: a Cochrane systematic review of the randomized evidence
    Lucy J Coward
    Institute of Neurology, University College London, UK
    Stroke 36:905-11. 2005
    ..To evaluate the safety and efficacy of endovascular techniques, we conducted a systematic review of randomized studies that compared endovascular treatment with surgery for carotid stenosis...
  12. doi request reprint New ischaemic brain lesions on MRI after stenting or endarterectomy for symptomatic carotid stenosis: a substudy of the International Carotid Stenting Study (ICSS)
    Leo H Bonati
    Department of Neurology and Stroke Unit, University Hospital Basel, Basel, Switzerland
    Lancet Neurol 9:353-62. 2010
    ..We aimed to compare the rate of ischaemic brain injury detectable on MRI between the two groups...
  13. doi request reprint Strictly lobar microbleeds are associated with executive impairment in patients with ischemic stroke or transient ischemic attack
    Simone M Gregoire
    Department of Brain Repair and Rehabilitation, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, United Kingdom
    Stroke 44:1267-72. 2013
    ..We, therefore, investigated the cognitive impact of CMBs in a cohort of patients with ischemic stroke or transient ischemic attack...
  14. pmc Length of carotid stenosis predicts peri-procedural stroke or death and restenosis in patients randomized to endovascular treatment or endarterectomy
    Leo H Bonati
    Stroke Research Group, UCL Institute of Neurology, London, UK Department of Neurology and Stroke Unit, University Hospital Basel, Basel, Switzerland
    Int J Stroke 9:297-305. 2014
    ..Whether anatomy favors one treatment over the other in terms of safety or efficacy has not been investigated in randomized trials...
  15. doi request reprint Carotid stenting: is there an operator effect? A pooled analysis from the carotid stenting trialists' collaboration
    David Calvet
    From the Department of Neurology, Hopital Sainte Anne, Universite Paris Descartes, Inserm UMR894, Paris, France D C, J L M Department of Neurology and Julius Centre for Health Sciences and Patient Care A A and Department of Radiology W P M, University Medical Centre Utrecht, Utrecht, The Netherlands Department of Vascular Surgery, University Hospital Henri Mondor, Creteil, France J P B Department of Neurology and Stroke Unit, University Hospital Basel, Basel, Switzerland L H B Department of Brain Repair and Rehabilitation, Institute of Neurology, University College London, London, United Kingdom L H B, M M B Medical Statistics Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom J D Department of Vascular Surgery, Medical University, Innsbruck, Austria G F Department of Neuroradiology, Schleswig Holstein University Hospital, Kiel, Germany O J Department of Neurology, University Hospital Heidelberg, Heidelberg, Germany P A R and Clinical Research Unit, Hopital Europeen Georges Pompidou, Universite Rene Descartes, Paris, France G C
    Stroke 45:527-32. 2014
    ..We examined whether operator experience is associated with 30-day risk of stroke or death in the Carotid Stenting Trialists' Collaboration database...
  16. doi request reprint Vascular intervention in stroke prevention: endarterectomy and angioplasty
    Jörg Ederle
    Stroke Research Group, UCL Institute of Neurology, London, UK
    Cerebrovasc Dis 27:134-9. 2009
    ..More data from ongoing randomised trials of stenting versus endarterectomy are needed to determine the role of stenting in the treatment of carotid stenosis...
  17. pmc Carotid artery stenting compared with endarterectomy in patients with symptomatic carotid stenosis (International Carotid Stenting Study): an interim analysis of a randomised controlled trial
    Jörg Ederle
    Institute of Neurology, University College London, Box 6, The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
    Lancet 375:985-97. 2010
    ..We compared the safety of carotid artery stenting with that of carotid endarterectomy...
  18. ncbi request reprint Circulating reticulated platelets in the early and late phases after ischaemic stroke and transient ischaemic attack
    Dominick J H McCabe
    Stroke Research Group, Institute of Neurology, The National Hospital for Neurology and Neurosurgery, University College London, London, UK
    Br J Haematol 126:861-9. 2004
    ....
  19. doi request reprint Association of cerebral microbleeds in acute ischemic stroke with high serum levels of vascular endothelial growth factor
    Pooja Dassan
    Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, Box 6, National Hospital of Neurology and Neurosurgery, Queen Square, London WC1N 3BG, England
    Arch Neurol 69:1186-9. 2012
    ..To determine whether vascular endothelial growth factor (VEGF) levels are associated with the presence of cerebral microbleeds (CMBs) in patients after acute ischemic stroke...
  20. pmc Ischemic brain lesions after carotid artery stenting increase future cerebrovascular risk
    Henrik Gensicke
    Department of Neurology and Stroke Center, University Hospital Basel, Basel, Switzerland
    J Am Coll Cardiol 65:521-9. 2015
    ..Brain lesions on diffusion-weighted imaging (DWI) are frequently found after carotid artery stenting (CAS), but their clinical relevance remains unclear...
  21. pmc Endovascular treatment with angioplasty or stenting versus endarterectomy in patients with carotid artery stenosis in the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS): long-term follow-up of a randomised trial
    Jörg Ederle
    Stroke Research Group, UCL Institute of Neurology, University College London, Queen Square, London, UK
    Lancet Neurol 8:898-907. 2009
    ..We therefore report the long-term results of the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS)...
  22. ncbi request reprint Long-term outcome after angioplasty and stenting for symptomatic vertebral artery stenosis compared with medical treatment in the Carotid And Vertebral Artery Transluminal Angioplasty Study (CAVATAS): a randomized trial
    Lucy J Coward
    Stroke Research Group, UCL Institute of Neurology, University College London, London, UK
    Stroke 38:1526-30. 2007
    ..We therefore compared these treatments in a randomized trial with long-term follow-up...
  23. doi request reprint Periprocedural hemodynamic depression is associated with a higher number of new ischemic brain lesions after stenting in the International Carotid Stenting Study-MRI Substudy
    Aysun Altinbas
    From the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus A Altinbas, A Algra, L J K, H B v d W, Julius Center for Health Sciences and Primary Care A Algra, I v d T, Department of Vascular Surgery G J d B, and Department of Radiology J H, University Medical Center Utrecht, Utrecht, The Netherlands Department of Brain Repair and Rehabilitation, Institute of Neurology, University College London, London, United Kingdom L H B, M M B and Department of Neurology and Stroke Unit, University Hospital Basel, Basel, Switzerland L H B
    Stroke 45:146-51. 2014
    ..We assessed whether the occurrence of hemodynamic depression is associated with these lesions in patients with symptomatic carotid stenosis treated by CAS or CEA in the randomized International Carotid Stenting Study (ICSS)-MRI substudy...
  24. doi request reprint MRI detection of new microbleeds in patients with ischemic stroke: five-year cohort follow-up study
    Simone M Gregoire
    Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, London, UK
    Stroke 41:184-6. 2010
    ..We studied the incidence of new microbleeds in a cohort of patients with ischemic stroke or transient ischemic attack screened for microbleeds at baseline...
  25. doi request reprint Value of measuring serum vascular endothelial growth factor levels in diagnosing acute ischemic stroke
    Pooja Dassan
    Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, UK
    Int J Stroke 7:454-9. 2012
    ..The aim of this prospective study was to ascertain whether serum vascular endothelial growth factor measurements could be used to distinguish between acute ischemic stroke and common stroke mimics in the emergency room...
  26. doi request reprint Randomized controlled trials comparing endarterectomy and endovascular treatment for carotid artery stenosis: a Cochrane systematic review
    Jörg Ederle
    UCL Institute of Neurology, University College London, UK
    Stroke 40:1373-80. 2009
    ..Endovascular treatment of carotid stenosis may be an alternative to surgical endarterectomy. We conducted a systematic review of the randomized evidence to assess the benefits and risks of endovascular treatment compared to surgery...
  27. ncbi request reprint International carotid stenting study: protocol for a randomised clinical trial comparing carotid stenting with endarterectomy in symptomatic carotid artery stenosis
    Roland L Featherstone
    Institute of Neurology, University College London, London, UK
    Cerebrovasc Dis 18:69-74. 2004
    ..The objectives of the ICSS are to compare the risks, benefits and cost-effectiveness of a treatment policy of referral for carotid stenting compared with referral for carotid endarterectomy...
  28. ncbi request reprint The evidence for medicine versus surgery for carotid stenosis
    Jörg Ederle
    Stroke Research Group, UCL Institute of Neurology, London, UK
    Eur J Radiol 60:3-7. 2006
    ..Those that opt for medical management alone should be advised to seek urgent medical attention should they become symptomatic in the future...
  29. doi request reprint A clinical rule (sex, contralateral occlusion, age, and restenosis) to select patients for stenting versus carotid endarterectomy: systematic review of observational studies with validation in randomized trials
    Emmanuel Touze
    From the Université Paris Descartes, Sorbonne Paris Cité, INSERM UMR S894, Service de Neurologie, Hopital Sainte Anne, Paris, France E T, G M, J L M Université de Caen Basse Normandie, Inserm UMR S U919, Service de Neurologie, CHU Cote de Nacre, Caen, France E T French Cochrane Centre, Universite Paris Descartes, Sorbonne Paris Cité, INSERM U738, Assistance Publique Hopitaux de Paris, Hopital Hotel Dieu, Centre d Epidemiologie Clinique, Paris, France L T Neurology Department, Hospital Santo Antonio, Centro Hospitalar do Porto, Largo Professor Abel Salazar, Porto, Portugal R F Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand K R Department of Neurology and Stroke Unit, University Hospital Basel, Switzerland L H B Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, Queen Square, London, UK L H B, M M B Department of Neurology
    Stroke 44:3394-400. 2013
    ..However, after the perioperative period, risk is similar with both treatments, suggesting that CAS could be an acceptable option in selected patients...
  30. ncbi request reprint Restenosis after carotid angioplasty, stenting, or endarterectomy in the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS)
    Dominick J H McCabe
    Stroke Research Group, Institute of Neurology, University College London, UK
    Stroke 36:281-6. 2005
    ..The rates of residual severe stenosis and restenosis and their contribution to recurrent symptoms was unclear...
  31. doi request reprint Should carotid stenting replace carotid endarterectomy in routine clinical practice?
    Martin M Brown
    UCL Institute of Neurology, Box 6, The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
    Pract Neurol 8:39-45. 2008
    ..We therefore need more data from the ongoing randomised trials before recommending that stenting should in general replace endarterectomy for either symptomatic or asymptomatic carotid stenosis...
  32. doi request reprint Criteria for a clinically informative serum biomarker in acute ischaemic stroke: a review of S100B
    Pooja Dassan
    Stroke Research Group, UCL Institute of Neurology, National Hospital of Neurology and Neurosurgery, London, UK
    Cerebrovasc Dis 27:295-302. 2009
    ..Serum S100B has been widely studied as a biomarker in acute ischaemic stroke. The main objective of this review was to appraise the published literature on S100B and determine its clinical applicability...
  33. doi request reprint Stroke prevention
    Jörg Ederle
    Stroke Research Group, UCL Institute of Neurology, London, UK
    Herz 33:518-23. 2008
    ..Symptomatic carotid stenosis should be treated by carotid endarterectomy. Stenting should be reserved for patients with contraindications to surgery or in the setting of clinical randomized trials...
  34. doi request reprint Ultrasonic plaque echolucency and emboli signals predict stroke in asymptomatic carotid stenosis
    R Topakian
    Clinical Neuroscience, St Georges University of London, London, UK
    Neurology 77:751-8. 2011
    ..We explored the predictive value of a score based on these 2 measures in the prospective, observational, international multicenter Asymptomatic Carotid Emboli Study...
  35. pmc Longitudinal changes in cerebral response to proprioceptive input in individual patients after stroke: an FMRI study
    Nick S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, London, UK
    Neurorehabil Neural Repair 20:398-405. 2006
    ..The authors set out to demonstrate the feasibility of using fMRI to investigate mechanisms of recovery in individual patients presenting with severe motor impairment...
  36. ncbi request reprint Cognitive dysfunction in patients with cerebral microbleeds on T2*-weighted gradient-echo MRI
    David J Werring
    Stroke Research Group, Department of Clinical Neurology, Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK
    Brain 127:2265-75. 2004
    ..These findings have implications for the diagnosis of stroke patients with cognitive impairment, and for the appropriate use of antihypertensive and antiplatelet treatments in these patients...
  37. ncbi request reprint Platelet degranulation and monocyte-platelet complex formation are increased in the acute and convalescent phases after ischaemic stroke or transient ischaemic attack
    Dominick J H McCabe
    Stroke Research Unit, Department of Headache, Brain Injury and Rehabilitation, Institute of Neurology, The National Hospital for Neurology and Neurosurgery, University College London, London, UK
    Br J Haematol 125:777-87. 2004
    ..This study provides evidence for ongoing excessive platelet and/or endothelial activation in ischaemic CVD patients despite treatment with antithrombotic therapy...
  38. ncbi request reprint Carotid artery stenting:the need for randomised trials
    Martin M Brown
    Institute of Neurology, University College London, London, UK
    Cerebrovasc Dis 18:57-61. 2004
    ..The result should determine whether carotid stenting truly rivals carotid endarterectomy as the treatment of choice for carotid stenosis...