John Brognard

Summary

Affiliation: University of Manchester
Country: UK

Publications

  1. ncbi Protein kinase signaling networks in cancer
    John Brognard
    Signalling Networks in Cancer Group, Cancer Research UK, Paterson Institute for Cancer Research, The University of Manchester, Manchester, UK
    Curr Opin Genet Dev 21:4-11. 2011
  2. ncbi Cancer-associated loss-of-function mutations implicate DAPK3 as a tumor-suppressing kinase
    John Brognard
    Signalling Networks in Cancer Group, Cancer Research UK, Paterson Institute for Cancer Research, The University of Manchester, Manchester, United Kingdom
    Cancer Res 71:3152-61. 2011

Collaborators

Detail Information

Publications2

  1. ncbi Protein kinase signaling networks in cancer
    John Brognard
    Signalling Networks in Cancer Group, Cancer Research UK, Paterson Institute for Cancer Research, The University of Manchester, Manchester, UK
    Curr Opin Genet Dev 21:4-11. 2011
    ..This review will highlight recent insights into known pathways essential for tumorigenesis and discuss exciting new pathways for therapeutic intervention...
  2. ncbi Cancer-associated loss-of-function mutations implicate DAPK3 as a tumor-suppressing kinase
    John Brognard
    Signalling Networks in Cancer Group, Cancer Research UK, Paterson Institute for Cancer Research, The University of Manchester, Manchester, United Kingdom
    Cancer Res 71:3152-61. 2011
    ..Our results suggest that DAPK3 is a tumor suppressor in which loss-of-function mutations promote increased cell survival, proliferation, cellular aggregation, and increased resistance to chemotherapy...