Malcolm Brodlie

Summary

Affiliation: University of Newcastle
Country: UK

Publications

  1. doi request reprint Vitamin D in children with cystic fibrosis
    Malcolm Brodlie
    Paediatric Respiratory Secretaries, Old Children s Outpatients Department, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Arch Dis Child 97:982-4. 2012
  2. ncbi request reprint Interference of electrocardiographic recordings by a mobile telephone
    Malcolm Brodlie
    Neonatal Unit, James Cook University Hospital, Middlesbrough, United Kingdom
    Cardiol Young 17:328-9. 2007
  3. doi request reprint Inflammatory myofibroblastic tumours of the respiratory tract: paediatric case series with varying clinical presentations
    M Brodlie
    Department of Respiratory Paediatrics, Newcastle upon Tyne Hospitals NHS Foundation Trust, Freeman Hospital, Newcastle upon Tyne, UK
    J Laryngol Otol 125:865-8. 2011
  4. doi request reprint Raised interleukin-17 is immunolocalised to neutrophils in cystic fibrosis lung disease
    M Brodlie
    Applied Immunobiology and Transplantation Group, Institute of Cellular Medicine, Newcastle University, and Department of Cardiopulmonary Transplantation, Newcastle upon Tyne Hospitals NHS Foundation Trust, Sir William Leech Centre for Lung Research, Freeman Hospital, Newcastle upon Tyne, NE7 7DN, UK
    Eur Respir J 37:1378-85. 2011
  5. doi request reprint Ceramide is increased in the lower airway epithelium of people with advanced cystic fibrosis lung disease
    Malcolm Brodlie
    Sir William Leech Centre for Lung Research, Freeman Hospital, Newcastle upon Tyne, UK
    Am J Respir Crit Care Med 182:369-75. 2010
  6. doi request reprint Primary bronchial epithelial cell culture from explanted cystic fibrosis lungs
    Malcolm Brodlie
    Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    Exp Lung Res 36:101-10. 2010
  7. doi request reprint Bronchomalacia occurring in monozygotic twins--further information about its inheritance
    Malcolm Brodlie
    Department of Respiratory Paediatrics, Newcastle upon Tyne Hospitals NHS Foundation Trust, Freeman Hospital, Newcastle upon Tyne, UK
    Acta Paediatr 98:1531-3. 2009
  8. doi request reprint Lymphoid bronchiolitis presenting at birth in an immunocompetent child: Chronic interstitial lung disease of unknown aetiology
    Malcolm Brodlie
    Department of Respiratory Paediatrics, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
    Pediatr Pulmonol 44:622-4. 2009
  9. pmc The critical role of TAK1 in accentuated epithelial to mesenchymal transition in obliterative bronchiolitis after lung transplantation
    Aaron Gardner
    Tissue Fibrosis and Repair Group, Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom
    Am J Pathol 180:2293-308. 2012
  10. doi request reprint Are the enzymatic methods currently being used to measure bronchoalveolar lavage bile salt levels fit for purpose?
    Shruti Parikh
    Institute for Cell and Molecular Biosciences, Newcastle University, Faculty of Medical Sciences, Newcastle upon Tyne, UK
    J Heart Lung Transplant 32:418-23. 2013

Collaborators

Detail Information

Publications11

  1. doi request reprint Vitamin D in children with cystic fibrosis
    Malcolm Brodlie
    Paediatric Respiratory Secretaries, Old Children s Outpatients Department, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Arch Dis Child 97:982-4. 2012
    ..In 2008 we found that only 10% of pancreatic insufficient (PI) children met this target. An increase in supplementation was implemented and a repeat audit performed in 2010...
  2. ncbi request reprint Interference of electrocardiographic recordings by a mobile telephone
    Malcolm Brodlie
    Neonatal Unit, James Cook University Hospital, Middlesbrough, United Kingdom
    Cardiol Young 17:328-9. 2007
    ..This is likely to be a common reason for poor quality electrocardiographic recordings...
  3. doi request reprint Inflammatory myofibroblastic tumours of the respiratory tract: paediatric case series with varying clinical presentations
    M Brodlie
    Department of Respiratory Paediatrics, Newcastle upon Tyne Hospitals NHS Foundation Trust, Freeman Hospital, Newcastle upon Tyne, UK
    J Laryngol Otol 125:865-8. 2011
    ..To highlight the clinical importance of inflammatory myofibroblastic tumours of the respiratory tract in children, and to present a case series of three children which illustrates this tumour's variable clinical presentation...
  4. doi request reprint Raised interleukin-17 is immunolocalised to neutrophils in cystic fibrosis lung disease
    M Brodlie
    Applied Immunobiology and Transplantation Group, Institute of Cellular Medicine, Newcastle University, and Department of Cardiopulmonary Transplantation, Newcastle upon Tyne Hospitals NHS Foundation Trust, Sir William Leech Centre for Lung Research, Freeman Hospital, Newcastle upon Tyne, NE7 7DN, UK
    Eur Respir J 37:1378-85. 2011
    ..IL-17 increases production of pro-neutrophilic mediators by CF epithelial cells, suggesting potential for a positive feedback element in airway inflammation...
  5. doi request reprint Ceramide is increased in the lower airway epithelium of people with advanced cystic fibrosis lung disease
    Malcolm Brodlie
    Sir William Leech Centre for Lung Research, Freeman Hospital, Newcastle upon Tyne, UK
    Am J Respir Crit Care Med 182:369-75. 2010
    ..Ceramide accumulates in the airway epithelium of mice deficient in cystic fibrosis transmembrane conductance regulator, resulting in susceptibility to Pseudomonas aeruginosa infection and inflammation...
  6. doi request reprint Primary bronchial epithelial cell culture from explanted cystic fibrosis lungs
    Malcolm Brodlie
    Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    Exp Lung Res 36:101-10. 2010
    ..This provides an important cellular model to elucidate the pathogenic mechanisms in cystic fibrosis lung disease and to investigate potential therapeutic targets...
  7. doi request reprint Bronchomalacia occurring in monozygotic twins--further information about its inheritance
    Malcolm Brodlie
    Department of Respiratory Paediatrics, Newcastle upon Tyne Hospitals NHS Foundation Trust, Freeman Hospital, Newcastle upon Tyne, UK
    Acta Paediatr 98:1531-3. 2009
    ..Conclusion: Left main-stem bronchomalacia occurring in monozygotic twins suggests that there may be a significant genetic component in some cases and provides further information about the inheritance of this condition...
  8. doi request reprint Lymphoid bronchiolitis presenting at birth in an immunocompetent child: Chronic interstitial lung disease of unknown aetiology
    Malcolm Brodlie
    Department of Respiratory Paediatrics, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
    Pediatr Pulmonol 44:622-4. 2009
    ....
  9. pmc The critical role of TAK1 in accentuated epithelial to mesenchymal transition in obliterative bronchiolitis after lung transplantation
    Aaron Gardner
    Tissue Fibrosis and Repair Group, Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom
    Am J Pathol 180:2293-308. 2012
    ..These data identify factors leading to and affected by accentuated and extended TAK1 phosphorylations potential novel therapeutic targets in inflammation-driven fibrotic diseases...
  10. doi request reprint Are the enzymatic methods currently being used to measure bronchoalveolar lavage bile salt levels fit for purpose?
    Shruti Parikh
    Institute for Cell and Molecular Biosciences, Newcastle University, Faculty of Medical Sciences, Newcastle upon Tyne, UK
    J Heart Lung Transplant 32:418-23. 2013
    ..2 ╬╝mol/liter, and the levels used to inform clinical decisions. This study assessed the sensitivity of detection by 2 enzymatic assay kits compared with tandem mass spectrometry...
  11. doi request reprint The oral corticosteroid-sparing effect of omalizumab in children with severe asthma
    Malcolm Brodlie
    Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK
    Arch Dis Child 97:604-9. 2012
    ..To report the oral corticosteroid-sparing effect of omalizumab in children with severe asthma...