V Braud

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi Functions of nonclassical MHC and non-MHC-encoded class I molecules
    V M Braud
    Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK
    Curr Opin Immunol 11:100-8. 1999
  2. ncbi The human major histocompatibility complex class Ib molecule HLA-E binds signal sequence-derived peptides with primary anchor residues at positions 2 and 9
    V Braud
    Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, GB
    Eur J Immunol 27:1164-9. 1997
  3. ncbi TAP- and tapasin-dependent HLA-E surface expression correlates with the binding of an MHC class I leader peptide
    V M Braud
    Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, OX3 9DS, UK
    Curr Biol 8:1-10. 1998
  4. ncbi HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C
    V M Braud
    Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK
    Nature 391:795-9. 1998
  5. ncbi Differential processing of influenza nucleoprotein in human and mouse cells
    V M Braud
    Molecular Immunology Group, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, GB
    Eur J Immunol 28:625-35. 1998
  6. ncbi Tetrameric complexes of human histocompatibility leukocyte antigen (HLA)-G bind to peripheral blood myelomonocytic cells
    D S Allan
    Institute of Molecular Medicine, John Radcliffe Hospital, Oxford OX3 9DS, United Kingdom
    J Exp Med 189:1149-56. 1999
  7. ncbi The proteasome-specific inhibitor lactacystin blocks presentation of cytotoxic T lymphocyte epitopes in human and murine cells
    V Cerundolo
    Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, GB
    Eur J Immunol 27:336-41. 1997
  8. ncbi Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E
    C A O'Callaghan
    Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, United Kingdom
    Mol Cell 1:531-41. 1998
  9. ncbi HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells
    A King
    Department of Pathology, University of Cambridge
    Eur J Immunol 30:1623-31. 2000
  10. ncbi Functional characterization of HLA-F and binding of HLA-F tetramers to ILT2 and ILT4 receptors
    E J Lepin
    Centre for Nephrology, Royal Free and University College Medical School, University College London, London, GB
    Eur J Immunol 30:3552-61. 2000

Collaborators

Detail Information

Publications13

  1. ncbi Functions of nonclassical MHC and non-MHC-encoded class I molecules
    V M Braud
    Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK
    Curr Opin Immunol 11:100-8. 1999
    ....
  2. ncbi The human major histocompatibility complex class Ib molecule HLA-E binds signal sequence-derived peptides with primary anchor residues at positions 2 and 9
    V Braud
    Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, GB
    Eur J Immunol 27:1164-9. 1997
    ..Using alanine and glycine substitutions, we could define primary anchor residues at positions 2 and 9 and secondary anchor residues at position 7 and possibly 3...
  3. ncbi TAP- and tapasin-dependent HLA-E surface expression correlates with the binding of an MHC class I leader peptide
    V M Braud
    Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, OX3 9DS, UK
    Curr Biol 8:1-10. 1998
    ..We have recently shown that HLA-E binds signal-sequence-derived peptides from human MHC class I molecules in vitro...
  4. ncbi HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C
    V M Braud
    Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK
    Nature 391:795-9. 1998
    ....
  5. ncbi Differential processing of influenza nucleoprotein in human and mouse cells
    V M Braud
    Molecular Immunology Group, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, GB
    Eur J Immunol 28:625-35. 1998
    ..These results therefore demonstrate a differential processing of the influenza nucleoprotein in mouse and human cells. This polymorphism influences the repertoire of peptides presented by MHC class I molecules at the cell surface...
  6. ncbi Tetrameric complexes of human histocompatibility leukocyte antigen (HLA)-G bind to peripheral blood myelomonocytic cells
    D S Allan
    Institute of Molecular Medicine, John Radcliffe Hospital, Oxford OX3 9DS, United Kingdom
    J Exp Med 189:1149-56. 1999
    ..These results suggest that the primary role of HLA-G may be the modulation of myelomonocytic cell behavior in pregnancy...
  7. ncbi The proteasome-specific inhibitor lactacystin blocks presentation of cytotoxic T lymphocyte epitopes in human and murine cells
    V Cerundolo
    Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, GB
    Eur J Immunol 27:336-41. 1997
    ..These results demonstrate that proteasome-dependent degradation plays an important role in the cytosolic generation of CTL epitopes...
  8. ncbi Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E
    C A O'Callaghan
    Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, United Kingdom
    Mol Cell 1:531-41. 1998
    ..These molecular adaptations make HLA-E a rigorous checkpoint at the cell surface reporting on the integrity of the antigen processing pathway to CD94/NKG2 receptor-bearing natural killer cells...
  9. ncbi HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells
    A King
    Department of Pathology, University of Cambridge
    Eur J Immunol 30:1623-31. 2000
    ....
  10. ncbi Functional characterization of HLA-F and binding of HLA-F tetramers to ILT2 and ILT4 receptors
    E J Lepin
    Centre for Nephrology, Royal Free and University College Medical School, University College London, London, GB
    Eur J Immunol 30:3552-61. 2000
    ..At the cell surface it would be capable of interacting with LIR1 (ILT2) and LIR2 (ILT4) receptors and so altering the activation threshold of immune effector cells...
  11. ncbi Intramembrane proteolysis of signal peptides: an essential step in the generation of HLA-E epitopes
    M K Lemberg
    Institute of Biochemistry, Swiss Federal Institute of Technology Eidgenössiche Technische Hochschule, Zurich, Switzerland
    J Immunol 167:6441-6. 2001
    ..This cut is essential for the release of the HLA-E epitope-containing fragment from the lipid bilayer and its subsequent transport into the lumen of the endoplasmic reticulum via the TAP...
  12. ncbi Viral evasion of natural killer cells during human cytomegalovirus infection
    V M Braud
    Centre National de la Recherche Scientifique, CNRS UMR 6097, Institut de Pharmacologie Moleculaire et Cellulaire, 660 route des Lucioles, Sophia Antipolis, 06560 Valbonne, France
    Curr Top Microbiol Immunol 269:117-29. 2002
    ..We focus in particular on a newly described protein, HCMV gpUL40, that induces cell surface expression of HLA-E, a non-classical class I molecule known to regulate NK cell functions...
  13. ncbi Effects of Chlamydia trachomatis infection on the expression of natural killer (NK) cell ligands and susceptibility to NK cell lysis
    C E Hook
    Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge UK
    Clin Exp Immunol 138:54-60. 2004
    ..A candidate activating signal is MICA/B, which was shown to be expressed constitutively on epithelial cells...