P J Brasted
Affiliation: University of Cambridge
- Striatal lesions produce distinctive impairments in reaction time performance in two different operant chambersP J Brasted
MRC Cambridge Centre for Brain Repair, University of Cambridge, UK
Brain Res Bull 46:487-93. 1998..Rather, the pattern of reaction time deficit after striatal lesions depends critically on the apparatus used and the precise response requirements for each task...
- Distinct roles for striatal subregions in mediating response processing revealed by focal excitotoxic lesionsP J Brasted
Medical Research Council Centre for Brain Repair, University of Cambridge, United Kingdom
Behav Neurosci 113:253-64. 1999..Discrete striatal areas are thus functionally dissociable, but both have a crucial role in the organization of responding in space...
- Embryonic donor age and dissection influences striatal graft development and functional integration in a rodent model of Huntington's diseaseC Watts
MRC Cambridge Centre for Brain Repair, University of Cambridge, Cambridge, United Kingdom
Exp Neurol 163:85-97. 2000..These results suggest that MGE tissue as well as LGE plays a role in the structural and functional integration of striatal grafts...
- Medial prefrontal and neostriatal lesions disrupt performance in an operant delayed alternation task in ratsS B Dunnett
MRC Cambridge Centre for Brain Repair and Department of Experimental Psychology, University of Cambridge, UK
Behav Brain Res 106:13-28. 1999..We conclude that the operant delayed alternation task should assist analysis of fronto-striatal function in rats as well as be useful for the analysis of strategies for fronto-striatal repair...
- The morphology, integration, and functional efficacy of striatal grafts differ between cell suspensions and tissue piecesC Watts
MRC Cambridge Centre for Brain Repair, Department of Neurosurgery, University of Cambridge, UK
Cell Transplant 9:395-407. 2000..No relationship was observed between functional effect and the graft anatomy. These results suggest that local graft host interaction may also be involved in graft-mediated functional recovery...