Phil Botha

Summary

Affiliation: University of Newcastle
Country: UK

Publications

  1. ncbi Smoking after cardiac transplantation
    P Botha
    Department of Cardiopulmonary Transplantation, Freeman Hospital, High Heaton, Newcastle upon Tyne, UK
    Am J Transplant 8:866-71. 2008
  2. ncbi Pseudomonas aeruginosa colonization of the allograft after lung transplantation and the risk of bronchiolitis obliterans syndrome
    Phil Botha
    Department of Cardiopulmonary Transplantation, Freeman Hospital, Newcastle upon Tyne, United Kingdom
    Transplantation 85:771-4. 2008
  3. ncbi Acute hemodynamic effects of intravenous sildenafil citrate in congestive heart failure: comparison of phosphodiesterase type-3 and -5 inhibition
    Phil Botha
    Department of Cardiopulmonary Transplantation, Freeman Hospital, Newcastle upon Tyne, United Kingdom
    J Heart Lung Transplant 28:676-82. 2009
  4. ncbi Sildenafil citrate augments myocardial protection in heart transplantation
    Phil Botha
    Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    Transplantation 89:169-77. 2010
  5. ncbi Inhaled nitric oxide for modulation of ischemia-reperfusion injury in lung transplantation
    Phil Botha
    Department of Cardiopulmonary Transplantation, Freeman Hospital, High Heaton, Newcastle upon Tyne, UK
    J Heart Lung Transplant 26:1199-205. 2007
  6. ncbi Marginal lung donors: A diminishing margin of safety?
    Phil Botha
    Department of Cardiopulmonary Transplantation, Freeman Hospital, Newcastle upon Tyne, United Kingdom
    Transplantation 82:1273-9. 2006
  7. ncbi Differential pulmonary vein gases predict primary graft dysfunction
    Phil Botha
    Department of Cardiopulmonary Transplantation, Freeman Hospital, High Heaton, Newcastle upon Tyne, United Kingdom
    Ann Thorac Surg 82:1998-2002. 2006
  8. ncbi Extended donor criteria in lung transplantation: impact on organ allocation
    Phil Botha
    Department of Cardio Pulmonary Transplantation, Freeman Hospital, High Heaton, Newcastle upon Tyne, United Kingdom
    J Thorac Cardiovasc Surg 131:1154-60. 2006
  9. ncbi Extended donor criteria in lung transplantation
    Phil Botha
    Department of Cardiopulmonary Transplantation, Freeman Hospital, Newcastle upon Tyne, United Kingdom
    Curr Opin Organ Transplant 14:206-10. 2009
  10. ncbi Current strategies in donor selection and management
    Phil Botha
    Department of Cardiopulmonary Transplantation, Freeman Hospital, Newcastle upon Tyne, United Kingdom
    Semin Thorac Cardiovasc Surg 20:143-51. 2008

Collaborators

Detail Information

Publications13

  1. ncbi Smoking after cardiac transplantation
    P Botha
    Department of Cardiopulmonary Transplantation, Freeman Hospital, High Heaton, Newcastle upon Tyne, UK
    Am J Transplant 8:866-71. 2008
    ..We hope that this information will deter cardiac transplant recipients from relapsing, and intensify efforts in improving cessation rates...
  2. ncbi Pseudomonas aeruginosa colonization of the allograft after lung transplantation and the risk of bronchiolitis obliterans syndrome
    Phil Botha
    Department of Cardiopulmonary Transplantation, Freeman Hospital, Newcastle upon Tyne, United Kingdom
    Transplantation 85:771-4. 2008
    ..We conclude that de novo colonization of the lung allograft by Pseudomonas is strongly associated with the subsequent development of BOS...
  3. ncbi Acute hemodynamic effects of intravenous sildenafil citrate in congestive heart failure: comparison of phosphodiesterase type-3 and -5 inhibition
    Phil Botha
    Department of Cardiopulmonary Transplantation, Freeman Hospital, Newcastle upon Tyne, United Kingdom
    J Heart Lung Transplant 28:676-82. 2009
    ..We contrasted the acute hemodynamic responses to intravenous PDE3 and PDE5 inhibitors in patients with congestive cardiac failure to assess their relative suitability for reversibility testing in this setting...
  4. ncbi Sildenafil citrate augments myocardial protection in heart transplantation
    Phil Botha
    Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    Transplantation 89:169-77. 2010
    ..Whether these effects could be used to enhance myocardial protection afforded by crystalloid cardioplegia, volatile anesthesia and hypothermia during cardiac transplantation remains to be established...
  5. ncbi Inhaled nitric oxide for modulation of ischemia-reperfusion injury in lung transplantation
    Phil Botha
    Department of Cardiopulmonary Transplantation, Freeman Hospital, High Heaton, Newcastle upon Tyne, UK
    J Heart Lung Transplant 26:1199-205. 2007
    ..We sought to assess the efficacy of NO in reducing neutrophil infiltration and associated injury if administered from the very onset of reperfusion in clinical lung transplantation...
  6. ncbi Marginal lung donors: A diminishing margin of safety?
    Phil Botha
    Department of Cardiopulmonary Transplantation, Freeman Hospital, Newcastle upon Tyne, United Kingdom
    Transplantation 82:1273-9. 2006
    ..We review the current literature focusing on recent developments in the pursuit of an expanded lung donor pool with acceptable outcomes...
  7. ncbi Differential pulmonary vein gases predict primary graft dysfunction
    Phil Botha
    Department of Cardiopulmonary Transplantation, Freeman Hospital, High Heaton, Newcastle upon Tyne, United Kingdom
    Ann Thorac Surg 82:1998-2002. 2006
    ..We assessed the utility of reduced pulmonary vein gas (PVG) partial pressure of oxygen (PO2) in predicting the incidence of primary graft dysfunction...
  8. ncbi Extended donor criteria in lung transplantation: impact on organ allocation
    Phil Botha
    Department of Cardio Pulmonary Transplantation, Freeman Hospital, High Heaton, Newcastle upon Tyne, United Kingdom
    J Thorac Cardiovasc Surg 131:1154-60. 2006
    ..None have evaluated how outcomes compare with the use of these organs for single and bilateral transplantation or whether this practice results in a higher incidence of early bronchiolitis obliterans syndrome...
  9. ncbi Extended donor criteria in lung transplantation
    Phil Botha
    Department of Cardiopulmonary Transplantation, Freeman Hospital, Newcastle upon Tyne, United Kingdom
    Curr Opin Organ Transplant 14:206-10. 2009
    ..Improved use of the available pool of cadaveric organ donors, therefore, represents one of few immediately available strategies to alleviate organ shortages...
  10. ncbi Current strategies in donor selection and management
    Phil Botha
    Department of Cardiopulmonary Transplantation, Freeman Hospital, Newcastle upon Tyne, United Kingdom
    Semin Thorac Cardiovasc Surg 20:143-51. 2008
    ..Algorithms based on this knowledge can be proposed with some confidence, but proving their clinical worth is a challenge for the future...
  11. ncbi Is CFTR-delF508 really absent from the apical membrane of the airway epithelium?
    Lee A Borthwick
    Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    PLoS ONE 6:e23226. 2011
    ..By sampling CF and non-CF epithelium simultaneously from the same individual, confounding factors of different airway microenvironments which may have influenced previous observations can be overcome...
  12. ncbi Exchange transfusion during extra corporeal membrane oxygenation used as a bridge to ABO-mismatch cardiac transplantation
    Phil Botha
    Department of Cardiothoracic Surgery and Transplantation, Freeman Hospital, High Heaton, Newcastle upon Tyne, United Kingdom
    Ann Thorac Surg 81:1105-7. 2006
    ..We believe our method to be a safe alternative, allowing ample time for immunological preparation for ABO-incompatible transplant...
  13. ncbi Clinical experience with assisted venous drainage cardiopulmonary bypass in elective cardiac reoperations
    Brian Nyawo
    Department of Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne, United Kingdom
    Heart Surg Forum 11:E21-3. 2008
    ..In cases in which structural damage did occur, blood loss was minimal...