C A G BorehamSummaryAffiliation: University of Ulster Country: UK Publications
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Publications
A common insertion/deletion polymorphism of the thymidylate synthase (TYMS) gene is a determinant of red blood cell folate and homocysteine concentrationsCarmel Kealey
Department of Pharmacology, University of Pennsylvania School of Medicine, 153 Johnson Pavilion, 3620 Hamilton Walk, Philadelphia, PA 19104 6084, USA
Hum Genet 116:347-53. 2005....
The effect of a worksite based walking programme on cardiovascular risk in previously sedentary civil servants [NCT00284479]Marie H Murphy
Sport and Exercise Sciences Research Institute, University of Ulster, Northern Ireland, UK
BMC Public Health 6:136. 2006..This study examined the effects of 45 minutes self-paced walking, 2 d. wk(-1) on aerobic fitness, blood pressure (BP), body composition, lipids and C-Reactive Protein (CRP) in previously sedentary civil servants...
Training effects of short bouts of stair climbing on cardiorespiratory fitness, blood lipids, and homocysteine in sedentary young womenC A G Boreham
Department of Sport and Exercise Science, University of Ulster at Jordanstown, Newtownabbey, Co Antrim, Northern Ireland, UK
Br J Sports Med 39:590-3. 2005..To study the training effects of eight weeks of stair climbing on Vo2max, blood lipids, and homocysteine in sedentary, but otherwise healthy young women...- Cardiorespiratory fitness, physical activity, and arterial stiffness: the Northern Ireland Young Hearts ProjectColin A Boreham
School of Applied Medical Sciences and Sports Studies, University of Ulster, Jordanstown, Northern Ireland, BT37 0QB United Kingdom
Hypertension 44:721-6. 2004..These findings suggest that arterial stiffness-related benefits of exercise are most likely to accrue if exercise prescription in young adults targets improvements in cardiorespiratory fitness... - Tracking of energy and nutrient intakes from adolescence to young adulthood: the experiences of the Young Hearts Project, Northern IrelandA M Gallagher
Northern Ireland Centre for Food and Health NICHE, University of Ulster, Coleraine, UK
Public Health Nutr 9:1027-34. 2006..To assess tracking of energy and nutrient intakes between adolescence and young adulthood... - The effect of nutrient intake on bone mineral status in young adults: the Northern Ireland young hearts projectC E Neville
School of Applied Medical Sciences and Sports Studies, University of Ulster, Jordanstown, Northern Ireland
Calcif Tissue Int 70:89-98. 2002..Intakes of Ca reported by adolescent males also had a strong negative effect on lumbar spine BMD measured at young adulthood... - Fruit and vegetable consumption and bone mineral density: the Northern Ireland Young Hearts ProjectClaire P McGartland
Northern Ireland Center for Food and Health, University of Ulster, Coleraine, United Kingdom
Am J Clin Nutr 80:1019-23. 2004..Studies examining the relation between bone mineral density (BMD) and fruit and vegetable consumption during adolescence are rare... - The thymidylate synthase tandem repeat polymorphism is not associated with homocysteine concentrations in healthy young subjectsKaren S Brown
Department of Pharmacology and Center for Pharmacogenetics, University of Pennsylvania School of Medicine, 153 Johnson Pavilion, 3620 Hamilton Walk, Philadelphia, PA 19104 6084, USA
Hum Genet 114:182-5. 2004..Our findings indicate that the TYMS 3R3R genotype is not a determinant of homocysteine in this sample of healthy young Caucasian adults from Northern Ireland... - Genetic evidence that nitric oxide modulates homocysteine: the NOS3 894TT genotype is a risk factor for hyperhomocystenemiaKaren S Brown
Department of Pharmacology and Center for Pharmacogenetics, University of Pennsylvania School of Medicine, 153 Johnson Pavilion, 3620 Hamilton Walk, Philadelphia, PA 19104 6084, USA
Arterioscler Thromb Vasc Biol 23:1014-20. 2003..Nitric oxide may also modulate plasma homocysteine (tHcy) concentrations, either by direct inhibition of methionine synthase or via an indirect effect on folate catabolism... - The benefits of exercise for arterial stiffnessIsabel Ferreira
Department of Clinical Epidemiology and Medical Technology Assessment, Academic Hospital Maastricht, Maastricht, The Netherlands
Am J Hypertens 19:1037-8. 2006 - Association between the NAT1 1095C > A polymorphism and homocysteine concentrationAnna Stanisławska-Sachadyn
Department of Pharmacology and Center for Pharmacogenetics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6084, USA
Am J Med Genet A 140:2374-7. 2006 - Genetic and nutritional factors contributing to hyperhomocysteinemia in young adultsLeo A J Kluijtmans
Department of Pharmacology and Center for Pharmacogenetics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Blood 101:2483-8. 2003..These data underscore the potential benefits that may be gained by improving the dietary status of young adults, and provide support for the implementation of folate/B-vitamin food fortification programs... 
Evidence for sex differences in the determinants of homocysteine concentrationsAnna Stanisławska-Sachadyn
Department of Pharmacology and Center for Pharmacogenetics, University of Pennsylvania School of Medicine, 153 Johnson Pavilion, 3620 Hamilton Walk, Philadelphia, PA 19104 6084, USA
Mol Genet Metab 93:355-62. 2008..Among females, smokers (regardless of MTHFR genotype) appear to be at the highest risk, and to be the most vulnerable to a single factor (i.e. RBC folate) that is associated with homocysteine raising effects...- An insertion/deletion polymorphism of the dihydrofolate reductase (DHFR) gene is associated with serum and red blood cell folate concentrations in womenAnna Stanisławska-Sachadyn
Department of Pharmacology and Center for Pharmacogenetics, University of Pennsylvania School of Medicine, 153 Johnson Pavilion, 3620 Hamilton Walk, Philadelphia, PA, 19104 6084, USA
Hum Genet 123:289-95. 2008....