Guillaume Bompard

Summary

Affiliation: University of Birmingham
Country: UK

Publications

  1. ncbi request reprint Membrane targeting of protein tyrosine phosphatase PTPL1 through its FERM domain via binding to phosphatidylinositol 4,5-biphosphate
    Guillaume Bompard
    INSERM U540, Endocrinologie Moléculaire et Cellulaire des Cancers, Montpellier, France
    J Cell Sci 116:2519-30. 2003
  2. pmc Regulation of WASP/WAVE proteins: making a long story short
    Guillaume Bompard
    School of Biosciences, Division of Molecular Cell Biology, University of Birmingham, Birmingham B15 2TT, England, UK
    J Cell Biol 166:957-62. 2004
  3. ncbi request reprint Involvement of Rac in actin cytoskeleton rearrangements induced by MIM-B
    Guillaume Bompard
    School of Biosciences, Division of Molecular Cell Biology, University of Birmingham, Edgbaston, Birmingham, B15 2TT UK
    J Cell Sci 118:5393-403. 2005
  4. ncbi request reprint [PTPL1, a proapoptotic protein tyrosine phosphatase in breast cancers]
    Gilles Freiss
    INSERM U540, Endocrinologie Moléculaire et Cellulaire des Cancers, 60, rue de Navacelles, 34090 Montpellier
    Bull Cancer 91:325-32. 2004
  5. pmc Structural basis of filopodia formation induced by the IRSp53/MIM homology domain of human IRSp53
    Thomas H Millard
    School of Biosciences, The University of Birmingham, Edgbaston, Birmingham, UK
    EMBO J 24:240-50. 2005
  6. ncbi request reprint Protein-tyrosine phosphatase PTPL1/FAP-1 triggers apoptosis in human breast cancer cells
    Guillaume Bompard
    INSERM, Unit 540, Molecular and Cellular Endocrinology of Cancers, 60 rue de Navacelles, 34090 Montpellier, France
    J Biol Chem 277:47861-9. 2002
  7. ncbi request reprint The putative tumor suppressor gene PTPN13/PTPL1 induces apoptosis through insulin receptor substrate-1 dephosphorylation
    Mathilde Dromard
    INSERM U826, Contrôle de la progression des cancers hormono dépendants, Centre de Recherche en Cancerologie, Universite Montpellier I, CRLC Val d Aurelle Paul Lamarque, 34298 Montpellier, France
    Cancer Res 67:6806-13. 2007
  8. pmc Inhibition of cytokinesis by wiskostatin does not rely on N-WASP/Arp2/3 complex pathway
    Guillaume Bompard
    CRBM, CNRS UMR 5237, Universite Montpellier I et II, 1919 Route de Mende, 34293 Montpellier Cedex 5, France
    BMC Cell Biol 9:42. 2008

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Membrane targeting of protein tyrosine phosphatase PTPL1 through its FERM domain via binding to phosphatidylinositol 4,5-biphosphate
    Guillaume Bompard
    INSERM U540, Endocrinologie Moléculaire et Cellulaire des Cancers, Montpellier, France
    J Cell Sci 116:2519-30. 2003
    ..These results identify the crucial role of the FERM domain in PTPL1 intracellular targeting and demonstrate that localization of PTPL1 is regulated by phosphoinositide metabolism...
  2. pmc Regulation of WASP/WAVE proteins: making a long story short
    Guillaume Bompard
    School of Biosciences, Division of Molecular Cell Biology, University of Birmingham, Birmingham B15 2TT, England, UK
    J Cell Biol 166:957-62. 2004
    ..New data also suggest additional functions for WASP family proteins, pushing us to reconsider existing models...
  3. ncbi request reprint Involvement of Rac in actin cytoskeleton rearrangements induced by MIM-B
    Guillaume Bompard
    School of Biosciences, Division of Molecular Cell Biology, University of Birmingham, Edgbaston, Birmingham, B15 2TT UK
    J Cell Sci 118:5393-403. 2005
    ..Thus, MIM-B is unlikely to be a metastasis suppressor but acts as a scaffold protein that interacts with Rac, actin and actin-associated proteins to modulate lamellipodia formation...
  4. ncbi request reprint [PTPL1, a proapoptotic protein tyrosine phosphatase in breast cancers]
    Gilles Freiss
    INSERM U540, Endocrinologie Moléculaire et Cellulaire des Cancers, 60, rue de Navacelles, 34090 Montpellier
    Bull Cancer 91:325-32. 2004
    ..Altogether PTPL1 has to be regarded as a unique marker of mammary tumor response to antiestrogens and a potential therapeutic target to activate apoptotic stimuli in tumor cells...
  5. pmc Structural basis of filopodia formation induced by the IRSp53/MIM homology domain of human IRSp53
    Thomas H Millard
    School of Biosciences, The University of Birmingham, Edgbaston, Birmingham, UK
    EMBO J 24:240-50. 2005
    ..This study promotes an expanded view of IRSp53 as an actin regulator that integrates scaffolding and effector functions...
  6. ncbi request reprint Protein-tyrosine phosphatase PTPL1/FAP-1 triggers apoptosis in human breast cancer cells
    Guillaume Bompard
    INSERM, Unit 540, Molecular and Cellular Endocrinology of Cancers, 60 rue de Navacelles, 34090 Montpellier, France
    J Biol Chem 277:47861-9. 2002
    ..Our data therefore suggest new therapeutic routes and strengthen the importance of identifying endogenous regulators and substrates of this phosphatase in breast tumors...
  7. ncbi request reprint The putative tumor suppressor gene PTPN13/PTPL1 induces apoptosis through insulin receptor substrate-1 dephosphorylation
    Mathilde Dromard
    INSERM U826, Contrôle de la progression des cancers hormono dépendants, Centre de Recherche en Cancerologie, Universite Montpellier I, CRLC Val d Aurelle Paul Lamarque, 34298 Montpellier, France
    Cancer Res 67:6806-13. 2007
    ..Altogether, these data provide the first evidence for a direct positive role of the putative tumor suppressor gene PTPL1/PTPN13 on apoptosis and identify its target in the IRS-1/PI3K/Akt signaling pathway...
  8. pmc Inhibition of cytokinesis by wiskostatin does not rely on N-WASP/Arp2/3 complex pathway
    Guillaume Bompard
    CRBM, CNRS UMR 5237, Universite Montpellier I et II, 1919 Route de Mende, 34293 Montpellier Cedex 5, France
    BMC Cell Biol 9:42. 2008
    ..The mechanisms of contractile ring formation are not fully understood but involve recruitment of preexisting actin filaments and de novo actin polymerisation...