Bobola N, Merabet S. Homeodomain proteins in action: similar DNA binding preferences, highly variable connectivity. Curr Opin Genet Dev. 2017;43:1-8 pubmed publisher
..Clarifying how homeodomain transcription factors work is central to our understanding of development, disease and evolution. ..
Amin S, Donaldson I, Zannino D, Hensman J, Rattray M, Losa M, et al. Hoxa2 selectively enhances Meis binding to change a branchial arch ground state. Dev Cell. 2015;32:265-77 pubmed publisher
..These findings show that Hoxa2 operates as a tissue-specific cofactor, enhancing Meis binding to specific sites that provide the IIBA with its anatomical identity. ..
Bobola N. From DNA binding to transcriptional activation: Is the TALE complete?. J Cell Biol. 2017;216:2603-2605 pubmed publisher
..In this issue, Hau et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201701154) show that the TALE TF MEIS recruits the histone modifier PARP1/ARTD1 at promoters to decompact chromatin and activate transcription. ..
Bobola N, Engist B. IGFBP5 is a potential regulator of craniofacial skeletogenesis. Genesis. 2008;46:52-9 pubmed publisher