Rosemary Bland

Summary

Affiliation: University of Warwick
Country: UK

Publications

  1. ncbi request reprint Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in pancreatic islets
    Rosemary Bland
    Department of Biological Sciences, Biomedical Research Institute, The University of Warwick, Coventry CV4 7AL, UK
    J Steroid Biochem Mol Biol 89:121-5. 2004
  2. ncbi request reprint High glucose up-regulates ENaC and SGK1 expression in HCD-cells
    Claire E Hills
    Molecular Physiology, Biomedical Research Institute, Department of Biological Sciences, University of Warwick, Coventry, UK
    Cell Physiol Biochem 18:337-46. 2006
  3. pmc Functional expression of TRPV4 channels in human collecting duct cells: implications for secondary hypertension in diabetic nephropathy
    Claire E Hills
    School of Life Sciences, The University of Warwick, Coventry CV4 7AL, UK
    Exp Diabetes Res 2012:936518. 2012
  4. doi request reprint Serum and glucocorticoid regulated kinase and disturbed renal sodium transport in diabetes
    Claire E Hills
    Department of Biological Sciences, Biomedical Research Institute, The University of Warwick, Coventry CV4 7AL, UK
    J Endocrinol 199:343-9. 2008
  5. doi request reprint Extracellular calcium-sensing receptor mediated signalling is involved in human vascular smooth muscle cell proliferation and apoptosis
    Guerman Molostvov
    The Clinical Sciences Research Institute, Warwick Medical School, Coventry, UK
    Cell Physiol Biochem 22:413-22. 2008
  6. pmc Reduction of the vitamin D hormonal system in kidney disease is associated with increased renal inflammation
    Daniel Zehnder
    Department of Nephrology, University Hospital Coventry and Warwickshire NHS Trust, Coventry, UK mail
    Kidney Int 74:1343-53. 2008
  7. ncbi request reprint Expression and role of the calcium-sensing receptor in the blood vessel wall
    Guerman Molostvov
    The Clinical Sciences Research Institute, Warwick Medical School and Department of Biological Sciences, The University of Warwick, Coventry, UK
    Curr Pharm Biotechnol 10:282-8. 2009
  8. ncbi request reprint Glucose-evoked alterations in connexin43-mediated cell-to-cell communication in human collecting duct: a possible role in diabetic nephropathy
    Claire E Hills
    Molecular Physiology, Biomedical Research Institute, Dept of Biological Sciences, Univ of Warwick, Coventry, CV4 7AL, UK
    Am J Physiol Renal Physiol 291:F1045-51. 2006
  9. ncbi request reprint Differential regulation of vitamin D receptor and its ligand in human monocyte-derived dendritic cells
    Martin Hewison
    Department of Medical Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom
    J Immunol 170:5382-90. 2003
  10. doi request reprint Phorbol ester-stimulated NF-kappaB-dependent transcription: roles for isoforms of novel protein kinase C
    Neil S Holden
    Airways Inflammation Group, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
    Cell Signal 20:1338-48. 2008

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in pancreatic islets
    Rosemary Bland
    Department of Biological Sciences, Biomedical Research Institute, The University of Warwick, Coventry CV4 7AL, UK
    J Steroid Biochem Mol Biol 89:121-5. 2004
    ..Therefore, we would postulate that local production of 1alpha,25(OH)(2)D(3) maybe an important autocrine link between Vitamin D status and pancreatic function...
  2. ncbi request reprint High glucose up-regulates ENaC and SGK1 expression in HCD-cells
    Claire E Hills
    Molecular Physiology, Biomedical Research Institute, Department of Biological Sciences, University of Warwick, Coventry, UK
    Cell Physiol Biochem 18:337-46. 2006
    ..However, the mechanisms by which glucose alters sodium re-uptake have not been fully characterised...
  3. pmc Functional expression of TRPV4 channels in human collecting duct cells: implications for secondary hypertension in diabetic nephropathy
    Claire E Hills
    School of Life Sciences, The University of Warwick, Coventry CV4 7AL, UK
    Exp Diabetes Res 2012:936518. 2012
    ..In the current study, we examine the functional expression of TRPV4 channels in cell volume regulation in cells of the human collecting duct...
  4. doi request reprint Serum and glucocorticoid regulated kinase and disturbed renal sodium transport in diabetes
    Claire E Hills
    Department of Biological Sciences, Biomedical Research Institute, The University of Warwick, Coventry CV4 7AL, UK
    J Endocrinol 199:343-9. 2008
    ..This short commentary considers the evidence that supports the involvement of SGK1 in diabetic hypertension, but also discusses how aberrant sodium reabsorption may account for the cellular changes seen in the nephron...
  5. doi request reprint Extracellular calcium-sensing receptor mediated signalling is involved in human vascular smooth muscle cell proliferation and apoptosis
    Guerman Molostvov
    The Clinical Sciences Research Institute, Warwick Medical School, Coventry, UK
    Cell Physiol Biochem 22:413-22. 2008
    ..05). In conclusion, stimulation of CaSR leads to activation of MEK1/ERK1,2 and PLC pathways and up-regulation of cell proliferation. CaSR-mediated PLC activation is important for SMC survival and protection against apoptosis...
  6. pmc Reduction of the vitamin D hormonal system in kidney disease is associated with increased renal inflammation
    Daniel Zehnder
    Department of Nephrology, University Hospital Coventry and Warwickshire NHS Trust, Coventry, UK mail
    Kidney Int 74:1343-53. 2008
    ..Our study indicates that renal inflammation is associated with decreased serum vitamin D metabolites and involves activation of the paracrine/autocrine vitamin D system...
  7. ncbi request reprint Expression and role of the calcium-sensing receptor in the blood vessel wall
    Guerman Molostvov
    The Clinical Sciences Research Institute, Warwick Medical School and Department of Biological Sciences, The University of Warwick, Coventry, UK
    Curr Pharm Biotechnol 10:282-8. 2009
    ..Further detailed analysis will clarify the role the vascular CaSR plays as a therapeutic target for complex disease conditions such as hypertension, tissue hypoperfusion, atherosclerosis and vascular calcification...
  8. ncbi request reprint Glucose-evoked alterations in connexin43-mediated cell-to-cell communication in human collecting duct: a possible role in diabetic nephropathy
    Claire E Hills
    Molecular Physiology, Biomedical Research Institute, Dept of Biological Sciences, Univ of Warwick, Coventry, CV4 7AL, UK
    Am J Physiol Renal Physiol 291:F1045-51. 2006
    ..Cx43 expression and cell-to-cell communication increased in response to high glucose and may protect the collecting duct from renal damage associated with more established diabetic nephropathy...
  9. ncbi request reprint Differential regulation of vitamin D receptor and its ligand in human monocyte-derived dendritic cells
    Martin Hewison
    Department of Medical Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom
    J Immunol 170:5382-90. 2003
    ..In conclusion, differential regulation of endogenous 1 alpha 25(OH)(2)D(3) ligand and its nuclear receptor appear to be important regulators of DC biology and represent potential targets for the manipulation of DC function...
  10. doi request reprint Phorbol ester-stimulated NF-kappaB-dependent transcription: roles for isoforms of novel protein kinase C
    Neil S Holden
    Airways Inflammation Group, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
    Cell Signal 20:1338-48. 2008
    ....
  11. ncbi request reprint Extracellular calcium-sensing receptor is functionally expressed in human artery
    Guerman Molostvov
    Clinical Sciences Research Institute, University of Warwick, Coventry, UK
    Am J Physiol Renal Physiol 293:F946-55. 2007
    ..Expression was significantly lower in arteries from ESRD patients. In conclusion, these data not only demonstrate the presence of a functional CaSR in human artery but show a correlation between CaSR expression and progression of CKD...
  12. ncbi request reprint Clonal differences in expression of 25-hydroxyvitamin D(3)-1alpha-hydroxylase, of 25-hydroxyvitamin D(3)-24-hydroxylase, and of the vitamin D receptor in human colon carcinoma cells: effects of epidermal growth factor and 1alpha,25-dihydroxyvitamin D(3)
    Petra Bareis
    Department of Pathophysiology, University of Vienna Medical School, Austria
    Exp Cell Res 276:320-7. 2002
    ....
  13. ncbi request reprint Synthesis of 1,25-dihydroxyvitamin D(3) by human endothelial cells is regulated by inflammatory cytokines: a novel autocrine determinant of vascular cell adhesion
    Daniel Zehnder
    Division of Medical Sciences, The University of Birmingham, Queen Elizabeth Hospital, Birmingham, UK
    J Am Soc Nephrol 13:621-9. 2002
    ..The rapid induction of endothelial 1alpha-OHase activity by inflammatory cytokines suggests a novel autocrine/paracrine role for the enzyme, possibly as a modulator of endothelial cell adhesion...