Ewan W Blanch

Summary

Affiliation: University of Manchester
Country: UK

Publications

  1. pmc Raman and Raman optical activity (ROA) analysis of RNA structural motifs in Domain I of the EMCV IRES
    Alison J Hobro
    Manchester Interdisciplinary Biocentre, Faculty of Life Sciences, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK
    Nucleic Acids Res 35:1169-77. 2007
  2. ncbi request reprint Selective DMSO-induced conformational changes in proteins from Raman optical activity
    Andrea N L Batista
    Manchester Institute of Biotechnology and Faculty of Life Sciences, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK
    Phys Chem Chem Phys 15:20147-52. 2013
  3. doi request reprint Detecting the early onset of shear-induced fibril formation of insulin in situ
    Grant T Webster
    Manchester Interdisciplinary Biocentre and Faculty of Life Sciences, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK
    J Phys Chem B 115:2617-26. 2011
  4. doi request reprint Multiobjective evolutionary optimisation for surface-enhanced Raman scattering
    Roger M Jarvis
    School of Chemistry, University of Manchester, Manchester Interdisciplinary Biocentre, 131 Princess Street, Manchester, M1 7DN, UK
    Anal Bioanal Chem 397:1893-901. 2010
  5. pmc Shear-induced unfolding of lysozyme monitored in situ
    Lorna Ashton
    Manchester Interdisciplinary Biocentre and Faculty of Life Sciences, University of Manchester, Manchester M1 7DN, United Kingdom
    Biophys J 96:4231-6. 2009
  6. doi request reprint Enhancing surface enhanced Raman scattering (SERS) detection of propranolol with multiobjective evolutionary optimization
    Clare Levene
    Faculty of Life Sciences, Manchester Institute of Biotechnology, University of Manchester, UK
    Anal Chem 84:7899-905. 2012
  7. ncbi request reprint Quantification of casein phosphorylation with conformational interpretation using Raman spectroscopy
    Roger M Jarvis
    Manchester Interdisciplinary Biocentre, 131 Princess Street, Manchester, UKM1 7ND
    Analyst 132:1053-60. 2007
  8. pmc Determination of protein fold class from Raman or Raman optical activity spectra using random forests
    Myra Kinalwa
    Manchester Interdisciplinary Biocentre, The University of Manchester, 131 Princess Street, Manchester M1 7DN, United Kingdom
    Protein Sci 20:1668-74. 2011
  9. doi request reprint Phosphorylation detection and characterization in ribonucleotides using Raman and Raman optical activity (ROA) spectroscopies
    Saeideh Ostovarpour
    Manchester Interdisciplinary Biocentre and Faculty of Life Sciences, The University of Manchester, 131 Princess Street, Manchester M1 7DN, UK
    Appl Spectrosc 66:289-93. 2012
  10. doi request reprint A new route to carbohydrate secondary and tertiary structure using Raman spectroscopy and Raman optical activity
    Nicola R Yaffe
    Manchester Interdisciplinary Biocentre, The University of Manchester, 131 Princess Street, Manchester M1 7DN, UK
    J Am Chem Soc 132:10654-5. 2010

Collaborators

Detail Information

Publications13

  1. pmc Raman and Raman optical activity (ROA) analysis of RNA structural motifs in Domain I of the EMCV IRES
    Alison J Hobro
    Manchester Interdisciplinary Biocentre, Faculty of Life Sciences, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK
    Nucleic Acids Res 35:1169-77. 2007
    ....
  2. ncbi request reprint Selective DMSO-induced conformational changes in proteins from Raman optical activity
    Andrea N L Batista
    Manchester Institute of Biotechnology and Faculty of Life Sciences, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK
    Phys Chem Chem Phys 15:20147-52. 2013
    ....
  3. doi request reprint Detecting the early onset of shear-induced fibril formation of insulin in situ
    Grant T Webster
    Manchester Interdisciplinary Biocentre and Faculty of Life Sciences, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK
    J Phys Chem B 115:2617-26. 2011
    ....
  4. doi request reprint Multiobjective evolutionary optimisation for surface-enhanced Raman scattering
    Roger M Jarvis
    School of Chemistry, University of Manchester, Manchester Interdisciplinary Biocentre, 131 Princess Street, Manchester, M1 7DN, UK
    Anal Bioanal Chem 397:1893-901. 2010
    ..Real experiments applying the evolutionary method to the SERS optimisation problem led to a 32% improvement in enhancement and reproducibility compared with the FF method, using far fewer evaluations...
  5. pmc Shear-induced unfolding of lysozyme monitored in situ
    Lorna Ashton
    Manchester Interdisciplinary Biocentre and Faculty of Life Sciences, University of Manchester, Manchester M1 7DN, United Kingdom
    Biophys J 96:4231-6. 2009
    ....
  6. doi request reprint Enhancing surface enhanced Raman scattering (SERS) detection of propranolol with multiobjective evolutionary optimization
    Clare Levene
    Faculty of Life Sciences, Manchester Institute of Biotechnology, University of Manchester, UK
    Anal Chem 84:7899-905. 2012
    ..36 ng/mL (7.97 nM) propranolol, and this is significantly lower (>25 times) than previous SERS studies aimed at detecting this β-blocker...
  7. ncbi request reprint Quantification of casein phosphorylation with conformational interpretation using Raman spectroscopy
    Roger M Jarvis
    Manchester Interdisciplinary Biocentre, 131 Princess Street, Manchester, UKM1 7ND
    Analyst 132:1053-60. 2007
    ..In addition, we have used these data in conjunction with Raman optical activity (ROA) spectra and NMR to assess the structural changes that occur upon phosphorylation...
  8. pmc Determination of protein fold class from Raman or Raman optical activity spectra using random forests
    Myra Kinalwa
    Manchester Interdisciplinary Biocentre, The University of Manchester, 131 Princess Street, Manchester M1 7DN, United Kingdom
    Protein Sci 20:1668-74. 2011
    ..The method also shows which spectral regions are most valuable in assigning fold class...
  9. doi request reprint Phosphorylation detection and characterization in ribonucleotides using Raman and Raman optical activity (ROA) spectroscopies
    Saeideh Ostovarpour
    Manchester Interdisciplinary Biocentre and Faculty of Life Sciences, The University of Manchester, 131 Princess Street, Manchester M1 7DN, UK
    Appl Spectrosc 66:289-93. 2012
    ..ROA spectra are shown to provide the most sensitive diagnostic tool for phosphorylation characterization and quantification...
  10. doi request reprint A new route to carbohydrate secondary and tertiary structure using Raman spectroscopy and Raman optical activity
    Nicola R Yaffe
    Manchester Interdisciplinary Biocentre, The University of Manchester, 131 Princess Street, Manchester M1 7DN, UK
    J Am Chem Soc 132:10654-5. 2010
    ..Furthermore, we show that the hyaluronan polymer does not adopt tertiary structure under near-physiological conditions, confirming a proposed model of hyaluronan structural organization...
  11. doi request reprint Raman and ROA spectra of (-)- and (+)-2-Br-hexahelicene: experimental and DFT studies of a π-conjugated chiral system
    Christian Johannessen
    Faculty of Life Sciences and Manchester Institute of Biotechnology, John Garside Building, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK
    J Phys Chem B 117:2221-30. 2013
    ..Through electron-phonon coupling analysis, we propose a mechanism that justifies the intense ROA signals...
  12. doi request reprint Use of a hydrogel polymer for reproducible surface enhanced Raman optical activity (SEROA)
    Saeideh Ostovar Pour
    Faculty of Life Sciences, Manchester Interdisciplinary Biocentre, The University of Manchester, 131 Princess Street, Manchester, UK M1 7DN
    Chem Commun (Camb) 47:4754-6. 2011
    ..By employing a gel forming polyacrylic acid to control colloid aggregation and associated birefringent artefacts we observe the first definitive proof of SEROA through measurement of mirror image bands for the two enantiomers...
  13. ncbi request reprint Two-dimensional Raman and Raman optical activity correlation analysis of the alpha-helix-to-disordered transition in poly(L-glutamic acid)
    Lorna Ashton
    Manchester Interdisciplinary Biocentre, Faculty of Life Sciences, University of Manchester, 131 Princess Street, Manchester, UKM1 7DN
    Analyst 132:468-79. 2007
    ....