R J Blair

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi request reprint Selective impairment in the recognition of anger induced by diazepam
    R J Blair
    Institute of Cognitive Neuroscience, London, UK
    Psychopharmacology (Berl) 147:335-8. 1999
  2. ncbi request reprint Impaired social response reversal. A case of 'acquired sociopathy'
    R J Blair
    Institute of Cognitive Neuroscience and Department of Psychology, University College London, UK
    Brain 123:1122-41. 2000
  3. ncbi request reprint Fractionation of visual memory: agency detection and its impairment in autism
    R J R Blair
    Institute of Cognitive Neuroscience, University College London, Alexandra House, 17 Queen Square, WC1H 3AR, London, UK
    Neuropsychologia 40:108-18. 2002
  4. pmc Neurocognitive models of aggression, the antisocial personality disorders, and psychopathy
    R J Blair
    Institute of Cognitive Neuroscience and Department of Psychology, University College London, UK
    J Neurol Neurosurg Psychiatry 71:727-31. 2001
  5. ncbi request reprint A selective impairment in the processing of sad and fearful expressions in children with psychopathic tendencies
    R J Blair
    Institute of Cognitive Neuroscience, University College London, England
    J Abnorm Child Psychol 29:491-8. 2001
  6. ncbi request reprint Somatic markers and response reversal: is there orbitofrontal cortex dysfunction in boys with psychopathic tendencies?
    R J Blair
    Institute of Cognitive Neuroscience, University College London, England
    J Abnorm Child Psychol 29:499-511. 2001
  7. ncbi request reprint Recognition of emotion in facial expressions and vocal tones in children with psychopathic tendencies
    D Stevens
    Department of Psychology, University College London, England
    J Genet Psychol 162:201-11. 2001
  8. ncbi request reprint Instrumental learning and relearning in individuals with psychopathy and in patients with lesions involving the amygdala or orbitofrontal cortex
    D G V Mitchell
    Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD 20892 2670, USA
    Neuropsychology 20:280-9. 2006
  9. ncbi request reprint Impaired recognition of fear facial expressions in 5-HTTLPR S-polymorphism carriers following tryptophan depletion
    Abigail A Marsh
    Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Psychopharmacology (Berl) 189:387-94. 2006
  10. pmc The impact of processing load on emotion
    D G V Mitchell
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Neuroimage 34:1299-309. 2007

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Selective impairment in the recognition of anger induced by diazepam
    R J Blair
    Institute of Cognitive Neuroscience, London, UK
    Psychopharmacology (Berl) 147:335-8. 1999
    ..Given this functional specialization of expression processing, it is plausible that these neurocognitive systems may also be dissociable pharmacologically...
  2. ncbi request reprint Impaired social response reversal. A case of 'acquired sociopathy'
    R J Blair
    Institute of Cognitive Neuroscience and Department of Psychology, University College London, UK
    Brain 123:1122-41. 2000
    ..Moreover, it is proposed that the orbitofrontal cortex may be implicated specifically either in the generation of these expectations or the use of these expectations to suppress inappropriate behaviour...
  3. ncbi request reprint Fractionation of visual memory: agency detection and its impairment in autism
    R J R Blair
    Institute of Cognitive Neuroscience, University College London, Alexandra House, 17 Queen Square, WC1H 3AR, London, UK
    Neuropsychologia 40:108-18. 2002
    ..The data is interpreted in terms of reduced sensitivity to agency cues in individuals with autism and general information processing capacity...
  4. pmc Neurocognitive models of aggression, the antisocial personality disorders, and psychopathy
    R J Blair
    Institute of Cognitive Neuroscience and Department of Psychology, University College London, UK
    J Neurol Neurosurg Psychiatry 71:727-31. 2001
    ....
  5. ncbi request reprint A selective impairment in the processing of sad and fearful expressions in children with psychopathic tendencies
    R J Blair
    Institute of Cognitive Neuroscience, University College London, England
    J Abnorm Child Psychol 29:491-8. 2001
    ..These results are interpreted with reference to an amygdala and empathy impairment explanation of psychopathy...
  6. ncbi request reprint Somatic markers and response reversal: is there orbitofrontal cortex dysfunction in boys with psychopathic tendencies?
    R J Blair
    Institute of Cognitive Neuroscience, University College London, England
    J Abnorm Child Psychol 29:499-511. 2001
    ..However, there were no group differences on the ID/ED task either for response reversal or extradimensional set shifting. The implications of these results for models of psychopathy are discussed...
  7. ncbi request reprint Recognition of emotion in facial expressions and vocal tones in children with psychopathic tendencies
    D Stevens
    Department of Psychology, University College London, England
    J Genet Psychol 162:201-11. 2001
    ..The results are interpreted with reference to the suggestion that the development of psychopathic tendencies may reflect early amygdala dysfunction (R. J. R. Blair, J. S. Morris, C. D. Frith, D. I. Perrett, & R. Dolan, 1999)...
  8. ncbi request reprint Instrumental learning and relearning in individuals with psychopathy and in patients with lesions involving the amygdala or orbitofrontal cortex
    D G V Mitchell
    Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD 20892 2670, USA
    Neuropsychology 20:280-9. 2006
    ..The results are interpreted with reference to current neurocognitive models of stimulus-reinforcement learning, relearning, and developmental psychopathy...
  9. ncbi request reprint Impaired recognition of fear facial expressions in 5-HTTLPR S-polymorphism carriers following tryptophan depletion
    Abigail A Marsh
    Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Psychopharmacology (Berl) 189:387-94. 2006
    ..Acute tryptophan depletion has been associated with the processing of fear-relevant cues, such as emotional expressions, but the effect of genotype at the 5-HTTLPR has not been assessed...
  10. pmc The impact of processing load on emotion
    D G V Mitchell
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Neuroimage 34:1299-309. 2007
    ..Together, the data suggest that the processing of task-irrelevant emotional information, like neutral information, is subject to the effects of processing load and is under top-down control...
  11. ncbi request reprint Dysfunctions of medial and lateral orbitofrontal cortex in psychopathy
    R J R Blair
    Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Ann N Y Acad Sci 1121:461-79. 2007
    ..It is suggested that the impairment in the role of medial OFC in prediction error signaling and the detection of contingency change may underlie the impairments in flexible behavioral change seen in psychopathy...
  12. pmc Deficits in facial affect recognition among antisocial populations: a meta-analysis
    Abigail A Marsh
    National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Neurosci Biobehav Rev 32:454-65. 2008
    ..This impairment cannot be attributed solely to task difficulty. These results suggest dysfunction among antisocial individuals in specified neural substrates, namely the amygdala, involved in processing fearful facial affect...
  13. ncbi request reprint The role of 5-HTTLPR in choosing the lesser of two evils, the better of two goods: examining the impact of 5-HTTLPR genotype and tryptophan depletion in object choice
    K S Blair
    Department of Health and Human Services, Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, 15K North Drive, Room 300A, MSC 2670, Bethesda, MD 20892 2670, USA
    Psychopharmacology (Berl) 196:29-38. 2008
    ..The serotonin (5-HT) system is considered important for decision-making. However, its role in reward- and punishment-based processing has not yet been clearly determined...
  14. ncbi request reprint Fine cuts of empathy and the amygdala: dissociable deficits in psychopathy and autism
    R J R Blair
    Anxiety Program, National Institute of Mental Health, Bethesda, MD 20892, USA
    Q J Exp Psychol (Hove) 61:157-70. 2008
    ..It is concluded that while both conditions can be considered disorders of social cognition, fine cuts can be made dissociating the impairments associated with each...
  15. pmc The interference of operant task performance by emotional distracters: an antagonistic relationship between the amygdala and frontoparietal cortices
    D G V Mitchell
    Department of Psychiatry and Department of Anatomy and Cell Biology, The University of Western Ontario, London, Canada
    Neuroimage 40:859-68. 2008
    ....
  16. doi request reprint Reduced amygdala response to fearful expressions in children and adolescents with callous-unemotional traits and disruptive behavior disorders
    Abigail A Marsh
    Mood and Anxiety Program, NIMH, 15K North Dr, MSC 2670, Bethesda, MD 20892, USA
    Am J Psychiatry 165:712-20. 2008
    ..Moreover, despite high comorbidity of callous-unemotional traits and attention deficit hyperactivity disorder (ADHD), no research has attempted to distinguish neural correlates of pediatric callous-unemotional traits and ADHD...
  17. pmc Response to emotional expressions in generalized social phobia and generalized anxiety disorder: evidence for separate disorders
    Karina Blair
    Mood and Anxiety Program, NIMH, NIH, 15K North Dr, MSC 2670, Bethesda, MD 20892, USA
    Am J Psychiatry 165:1193-202. 2008
    ..Functional magnetic resonance imaging assessed the neural response to facial expressions in generalized social phobia and generalized anxiety disorder...
  18. ncbi request reprint The emergence of psychopathy: implications for the neuropsychological approach to developmental disorders
    R J R Blair
    Mood and Anxiety Disorders Program, National Institute of Mental Health, USA
    Cognition 101:414-42. 2006
    ..However, caveats to the neuropsychological approach with reference to this disorder are noted...
  19. ncbi request reprint Divergent patterns of aggressive and neurocognitive characteristics in acquired versus developmental psychopathy
    D G V Mitchell
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Neurocase 12:164-78. 2006
    ....
  20. ncbi request reprint Theory of mind and psychopathy: can psychopathic individuals read the 'language of the eyes'?
    R A Richell
    Institute of Cognitive Neuroscience, Department of Psychology, University College, London, UK
    Neuropsychologia 41:523-6. 2003
    ..Results indicated that the psychopathic individuals did not present with any generalised impairment in ToM. The data are discussed with reference to the putative neural system mediating performance on this task and models of psychopathy...
  21. pmc Facial expressions, their communicatory functions and neuro-cognitive substrates
    R J R Blair
    Unit on Affective Cognitive Neuroscience, Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institute of Health, Department of Health and Human Services, Bethesda, MD 20892 2670, USA
    Philos Trans R Soc Lond B Biol Sci 358:561-72. 2003
    ..In acquired sociopathy, the response to angry expressions in particular is attenuated resulting in reduced regulation of social behaviour...
  22. ncbi request reprint The roles of orbital frontal cortex in the modulation of antisocial behavior
    R J R Blair
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, 15K North Drive, Room 206, MSC 2670, Bethesda, MD 20892 2670, USA
    Brain Cogn 55:198-208. 2004
    ..Impairments in response reversal are also seen in psychopathic individuals. However, it remains unclear whether impairment in response reversal per se is associated with antisocial behavior...
  23. ncbi request reprint Response reversal and children with psychopathic tendencies: success is a function of salience of contingency change
    S Budhani
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Heath, Department of Health and Human Services, Bethesda, Maryland 20892 2670, USA
    J Child Psychol Psychiatry 46:972-81. 2005
    ..Previous work has inconsistently reported difficulties with response reversal/extinction in children with psychopathic tendencies...
  24. ncbi request reprint Responding to the emotions of others: dissociating forms of empathy through the study of typical and psychiatric populations
    R J R Blair
    Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, 15K North Drive, Room 206, MSC 2670, Bethesda, MD 20892 2670, USA
    Conscious Cogn 14:698-718. 2005
    ..In contrast, individuals with psychopathy show clear difficulties with a specific form of emotional empathy but no indications of impairment with cognitive and motor empathy...
  25. ncbi request reprint Deficits on a probabilistic response-reversal task in patients with pediatric bipolar disorder
    Tristan Gorrindo
    Mood and Anxiety Program, National Institute of Mental Health, Bldg 10, Rm 4N 208, 10 Center Dr MSC 1255, Bethesda, MD 20892 1255, USA
    Am J Psychiatry 162:1975-7. 2005
    ....
  26. ncbi request reprint Applying a cognitive neuroscience perspective to the disorder of psychopathy
    R J R Blair
    Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD 20892 2670, USA
    Dev Psychopathol 17:865-91. 2005
    ..Some directions for future work are considered...
  27. ncbi request reprint The development of psychopathy
    R J R Blair
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Heath, Department of Health and Human Services, Bethesda, MD, USA
    J Child Psychol Psychiatry 47:262-76. 2006
    ..These impairments disrupt the impact of standard socialization techniques and increase the risk for frustration-induced reactive aggression respectively...
  28. ncbi request reprint Differentiating among prefrontal substrates in psychopathy: neuropsychological test findings
    K S Blair
    National Institute of Mental Health and University College, London, UK
    Neuropsychology 20:153-65. 2006
    ..In contrast, the 2 groups did not show impairment on the measures preferentially sensitive to the functioning of the DLPFC or ACC. These results are interpreted with reference to executive dysfunction accounts of the disorder...
  29. pmc Amygdala and ventrolateral prefrontal cortex function during anticipated peer evaluation in pediatric social anxiety
    Amanda E Guyer
    Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, 15K North Dr, Room 208, Bethesda, MD 20892 2670, USA
    Arch Gen Psychiatry 65:1303-12. 2008
    ..Such fear-circuitry dysfunction may also manifest when anticipated social evaluation leads socially anxious adolescents to misperceive peers as threatening...