Stephen C Bishop

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. pmc On the genetic interpretation of disease data
    Stephen C Bishop
    The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Roslin, Midlothian, United Kingdom
    PLoS ONE 5:e8940. 2010
  2. doi request reprint Possibilities to breed for resistance to nematode parasite infections in small ruminants in tropical production systems
    S C Bishop
    Division of Genetics and Genomics, The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Midlothian EH25 9RG, UK
    Animal 6:741-7. 2012
  3. pmc Uses and implications of field disease data for livestock genomic and genetics studies
    Stephen C Bishop
    The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh Edinburgh, UK
    Front Genet 3:114. 2012
  4. pmc A consideration of resistance and tolerance for ruminant nematode infections
    Stephen C Bishop
    Genetics and Genomics, Royal Dick School of Veterinary Studies, The Roslin Institute, University of Edinburgh Edinburgh, UK
    Front Genet 3:168. 2012
  5. pmc Adaptation of gastrointestinal nematode parasites to host genotype: single locus simulation models
    Kathryn E Kemper
    Department of Agriculture and Food Systems, University of Melbourne, Parkville, VIC 3010, Australia
    Genet Sel Evol 45:14. 2013
  6. pmc Characterisation of QTL-linked and genome-wide restriction site-associated DNA (RAD) markers in farmed Atlantic salmon
    Ross D Houston
    The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Midlothian, UK
    BMC Genomics 13:244. 2012
  7. pmc Traits associated with innate and adaptive immunity in pigs: heritability and associations with performance under different health status conditions
    Mary Clapperton
    The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Roslin, Midlothian, EH25 9PS, UK
    Genet Sel Evol 41:54. 2009
  8. pmc Genetic parameters for somatic cell score according to udder infection status in Valle del Belice dairy sheep and impact of imperfect diagnosis of infection
    Valentina Riggio
    Dipartimento S En Fi Mi Zo Sezione Produzioni Animali, Universita degli Studi di Palermo, Palermo, Italy
    Genet Sel Evol 42:30. 2010
  9. pmc A genetic epidemiological model to describe resistance to an endemic bacterial disease in livestock: application to footrot in sheep
    Gert Jan Nieuwhof
    Meat and Livestock Commission, Milton Keynes, UK
    Genet Sel Evol 41:19. 2009
  10. pmc Association of selected SNP with carcass and taste panel assessed meat quality traits in a commercial population of Aberdeen Angus-sired beef cattle
    Jennifer L Gill
    The Roslin Institute and Royal Dick School of Veterinary Studies, The University of Edinburgh, Roslin Biocentre, Roslin, Midlothian, UK
    Genet Sel Evol 41:36. 2009

Collaborators

  • Yan C S M Laurenson
  • Tahar Ait-Ali
  • Karim Gharbi
  • Mary Clapperton
  • Joan K Lunney
  • David J Penman
  • Michael Bekaert
  • June E Swinburne
  • Ross D Houston
  • Pamela Wiener
  • Jennifer L Gill
  • Simon J More
  • Donagh P Berry
  • Kwang Hyun Baek
  • C Haley
  • E J Glass
  • Serap Gonen
  • Laura J Corbin
  • Kathryn E Kemper
  • Carolina Peñaloza
  • Zeenath U Islam
  • John A Woolliams
  • Sem Genini
  • Mairéad L Bermingham
  • Elisabetta Giuffra
  • Stefano Biffani
  • Valentina Riggio
  • Gert Jan Nieuwhof
  • Simon Gubbins
  • Andreas Kranis
  • Sarah C Blott
  • Natalie R Lowe
  • Timothé Cézard
  • Mark Vaudin
  • Derrick R Guy
  • Alastair Hamilton
  • Benjamin Trible
  • Nicholas J Savill
  • Michael E Goddard
  • Andrea B Doeschl-Wilson
  • Raymond R R Rowland
  • Ingrid Olsaker
  • Paola Cremonesi
  • Bouabid Badaoui
  • Kirsty Jensen
  • Susan Brotherstone
  • Richard S Clifton-Hadley
  • Eliane Foulon
  • Sara H Downs
  • Andy P Mitchell
  • Gilles Foucras
  • Cédric Cabau
  • Alessandra Stella
  • Mike Coffey
  • Giuliano Pisoni
  • Marcello Del Corvo
  • Astrid De Greeff
  • Rachel Rupp
  • Bianca Castiglioni
  • Dave Waddington
  • Hilde E Smith
  • Hans Martin Seyfert
  • Gert Sclep
  • Wolfram Petzl
  • Mari A Smits
  • Isabella M Higgins
  • Sara Botti
  • Paolo Moroni
  • Christophe Klopp
  • Marie Helene Pinard van der Laan
  • Margaret Good
  • Guro M Boman
  • Andrew R Cromie
  • Ian Ms White
  • Baldassare Portolano
  • Henk Bovenhuis
  • Eurion Thomas
  • Kay Boulton
  • Will Haresign
  • Kieran Hyder
  • Joanne Conington
  • Charlotte J Cook
  • Carol Davis
  • Rachel D Eglin
  • Beatriz Villanueva

Detail Information

Publications28

  1. pmc On the genetic interpretation of disease data
    Stephen C Bishop
    The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Roslin, Midlothian, United Kingdom
    PLoS ONE 5:e8940. 2010
    ..Our focus is on variance component estimation and we introduce epidemiological concepts to quantitative genetics...
  2. doi request reprint Possibilities to breed for resistance to nematode parasite infections in small ruminants in tropical production systems
    S C Bishop
    Division of Genetics and Genomics, The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Midlothian EH25 9RG, UK
    Animal 6:741-7. 2012
    ..There is no empirical evidence to suggest that nematodes will evolve rapidly in response to resistant hosts, and mathematical models based on genetic and biological principles also suggest that resistance should be sustainable...
  3. pmc Uses and implications of field disease data for livestock genomic and genetics studies
    Stephen C Bishop
    The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh Edinburgh, UK
    Front Genet 3:114. 2012
    ..Solving these problems would add insight to both disease genetic and epidemiological studies, as well as enabling us to better select animals for increased disease resistance...
  4. pmc A consideration of resistance and tolerance for ruminant nematode infections
    Stephen C Bishop
    Genetics and Genomics, Royal Dick School of Veterinary Studies, The Roslin Institute, University of Edinburgh Edinburgh, UK
    Front Genet 3:168. 2012
    ..This may help to customise breeding objectives, with tolerance given greater weight in heavily parasitized environments...
  5. pmc Adaptation of gastrointestinal nematode parasites to host genotype: single locus simulation models
    Kathryn E Kemper
    Department of Agriculture and Food Systems, University of Melbourne, Parkville, VIC 3010, Australia
    Genet Sel Evol 45:14. 2013
    ..We describe the requirements for adaptation and test if worm adaptation (1) is slowed by non-genetic features of worm infections and (2) can occur with little observable change in faecal worm egg count...
  6. pmc Characterisation of QTL-linked and genome-wide restriction site-associated DNA (RAD) markers in farmed Atlantic salmon
    Ross D Houston
    The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Midlothian, UK
    BMC Genomics 13:244. 2012
    ..From each family, the genomic DNA of the two heterozygous parents and seven offspring of each IPN phenotype and genotype was digested with the SbfI enzyme and sequenced in multiplexed pools...
  7. pmc Traits associated with innate and adaptive immunity in pigs: heritability and associations with performance under different health status conditions
    Mary Clapperton
    The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Roslin, Midlothian, EH25 9PS, UK
    Genet Sel Evol 41:54. 2009
    ....
  8. pmc Genetic parameters for somatic cell score according to udder infection status in Valle del Belice dairy sheep and impact of imperfect diagnosis of infection
    Valentina Riggio
    Dipartimento S En Fi Mi Zo Sezione Produzioni Animali, Universita degli Studi di Palermo, Palermo, Italy
    Genet Sel Evol 42:30. 2010
    ....
  9. pmc A genetic epidemiological model to describe resistance to an endemic bacterial disease in livestock: application to footrot in sheep
    Gert Jan Nieuwhof
    Meat and Livestock Commission, Milton Keynes, UK
    Genet Sel Evol 41:19. 2009
    ..g. 2-5 generations)...
  10. pmc Association of selected SNP with carcass and taste panel assessed meat quality traits in a commercial population of Aberdeen Angus-sired beef cattle
    Jennifer L Gill
    The Roslin Institute and Royal Dick School of Veterinary Studies, The University of Edinburgh, Roslin Biocentre, Roslin, Midlothian, UK
    Genet Sel Evol 41:36. 2009
    ....
  11. pmc Associations between lamb survival and prion protein genotype: analysis of data for ten sheep breeds in Great Britain
    Simon Gubbins
    Centre for Epidemiology and Risk Analysis, Veterinary Laboratories Agency, Woodham Lane, New Haw, Addlestone, Surrey, KT15 3NB, UK
    BMC Vet Res 5:3. 2009
    ..In addition, the reasons for lamb deaths were examined in order to identify any associations between these and PrP genotype...
  12. pmc Using SNP array data to test for host genetic and breed effects on Porcine Reproductive and Respiratory Syndrome Viremia
    Stefano Biffani
    Parco Tecnologico Padano Loc, Cascina Codazza, Via A, Einstein, 26900 Lodi Italy
    BMC Proc 5:S28. 2011
    ..A binomial logistic model was used to investigate the relationship between breed-clusters and PRRSV susceptibility. Breed-clusters were defined using the matrix of genomic kinship between all pairs of piglets...
  13. pmc Evidence for genetic variance in resistance to tuberculosis in Great Britain and Irish Holstein-Friesian populations
    Mairéad L Bermingham
    The Roslin Institute, Roslin Biocentre, Roslin, Midlothian EH25 9RG, UK
    BMC Proc 5:S15. 2011
    ....
  14. pmc Report from the second international symposium on animal genomics for animal health: critical needs, challenges and potential solutions
    Steve C Bishop
    Office of National Programs, ARS, REE, USDA, 5601 Sunnyside Ave, Beltsville, MD 20705, USA
    BMC Proc 5:S1. 2011
    ..This report captures key points made by symposium participants during the roundtable discussion and serves as a roadmap to steer future research priorities in animal genomics research...
  15. pmc Strengthening insights into host responses to mastitis infection in ruminants by combining heterogeneous microarray data sources
    Sem Genini
    Parco Tecnologico Padano CERSA, Via Einstein, 26900 Lodi, Italy
    BMC Genomics 12:225. 2011
    ..aureus. We combined different time points from those studies, testing different responses to mastitis infection: overall (common signature), early stage, late stage, and cattle-specific...
  16. doi request reprint Modelling the short- and long-term impacts of drenching frequency and targeted selective treatment on the performance of grazing lambs and the emergence of anthelmintic resistance
    Yan C S M Laurenson
    The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Midlothian EH25 9RG, UK
    Parasitology 140:780-91. 2013
    ..TST and frequency of drenching may lead to different benefits in the short versus long term...
  17. doi request reprint Can we use genetic and genomic approaches to identify candidate animals for targeted selective treatment
    Yan C S M Laurenson
    The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Midlothian EH25 9RG, UK
    Vet Parasitol 197:379-83. 2013
    ....
  18. doi request reprint Host inhibits replication of European porcine reproductive and respiratory syndrome virus in macrophages by altering differential regulation of type-I interferon transcriptional response
    Tahar Ait-Ali
    The Roslin Institute and Royal Dick School of Veterinary Studies, The University of Edinburgh, Roslin, Midlothian EH25 9RG, UK
    Immunogenetics 63:437-48. 2011
    ....
  19. doi request reprint Functional analysis of the porcine USP18 and its role during porcine arterivirus replication
    Tahar Ait-Ali
    The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Roslin, Midlothian EH25 9PS, UK
    Gene 439:35-42. 2009
    ....
  20. pmc Linkage maps of the Atlantic salmon (Salmo salar) genome derived from RAD sequencing
    Serap Gonen
    The Roslin Institute, University of Edinburgh, Midlothian EH25 9RG, Scotland, UK
    BMC Genomics 15:166. 2014
    ..This paper describes the development and characterisation of a high density SNP linkage map based on SbfI RAD-Seq SNP markers from two Atlantic salmon reference families...
  21. ncbi request reprint Innate immune responses to replication of porcine reproductive and respiratory syndrome virus in isolated Swine alveolar macrophages
    Tahar Ait-Ali
    Roslin Institute, Roslin, Midlothian, United Kingdom
    Viral Immunol 20:105-18. 2007
    ....
  22. pmc Development and validation of a high density SNP genotyping array for Atlantic salmon (Salmo salar)
    Ross D Houston
    The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Midlothian EH25 9RG, UK
    BMC Genomics 15:90. 2014
    ..In Atlantic salmon (Salmo salar), these goals are currently hampered by the lack of a high-density SNP genotyping platform. Therefore, the aim of the study was to develop and test a dense Atlantic salmon SNP array...
  23. pmc The utility of low-density genotyping for imputation in the Thoroughbred horse
    Laura J Corbin
    Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK
    Genet Sel Evol 46:9. 2014
    ..In this study, we investigated the potential for low-density genotyping and subsequent imputation to address this problem...
  24. ncbi request reprint A SNP in the 5' flanking region of the myostatin-1b gene is associated with harvest traits in Atlantic salmon (Salmo salar)
    Carolina Peñaloza
    Division of Genetics and Genomics, The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Edinburgh, Midlothian EH25 9RG, UK
    BMC Genet 14:112. 2013
    ....
  25. pmc Quantitative Analysis of Porcine Reproductive and Respiratory Syndrome (PRRS) Viremia Profiles from Experimental Infection: A Statistical Modelling Approach
    Zeenath U Islam
    The Roslin Institute and R D SVS, University of Edinburgh, Edinburgh, Midlothian, United Kingdom
    PLoS ONE 8:e83567. 2013
    ..Our study provides novel insights into the nature and degree of variation of hosts' responses to infection as well as new informative traits for subsequent genomic and modelling studies. ..
  26. doi request reprint In silico exploration of the mechanisms that underlie parasite-induced anorexia in sheep
    Yan C S M Laurenson
    The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Midlothian EH25 9RG, UK
    Br J Nutr 106:1023-39. 2011
    ..In conclusion, available experimental data and model predictions were consistent with anorexia having an impact directly on food intake, and with impacts of anorexia increasing with decreasing protein content...
  27. pmc Major quantitative trait loci affect resistance to infectious pancreatic necrosis in Atlantic salmon (Salmo salar)
    Ross D Houston
    Division of Genetics and Genomics, Roslin Institute and Royal Dick School of Veterinary Studies, Roslin Biocentre, Midlothian, United Kingdom
    Genetics 178:1109-15. 2008
    ..The identified QTL can be applied in marker-assisted selection programs to improve the resistance of salmon to IPN and reduce disease-related mortality...
  28. pmc Genetic management strategies for controlling infectious diseases in livestock populations
    Stephen C Bishop
    Roslin Institute Edinburgh, Roslin, Midlothian, EH25 9PS, Scotland, UK
    Genet Sel Evol 35:S3-17. 2003
    ..Wherever possible a combination of genotypes should be used to minimise the invasion possibilities of pathogens that have mutated to overcome the effects of specific resistance alleles...