Research Topics
| R H BisbySummaryAffiliation: University of Salford Country: UK Publications
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Detail Information
Publications
Fluorescence lifetime imaging of E-combretastatin uptake and distribution in live mammalian cellsRoger H Bisby
School of Environment and Life Sciences, University of Salford, Salford M5 4WT, UK
Eur J Cancer 48:1896-903. 2012..Within the droplets the local concentrations may be up to two orders of magnitude higher than that of the drug in the surrounding medium...
Near infrared multiphoton-induced generation and detection of hydroxyl radicals in a biochemical systemStanley W Botchway
Biomedical Sciences Research Institute, University of Salford, Salford M5 4WT, UK
Arch Biochem Biophys 464:314-21. 2007..This method has potential applications in intracellular induction of oxidative stress using multiphoton near-infrared illumination, a technology that is gaining momentum as a research tool...- Nanoscale hydroxyl radical generation from multiphoton ionization of tryptophanRoger H Bisby
Biomedical Sciences Research Institute, University of Salford, Salford, UK
Photochem Photobiol 85:353-7. 2009..It is postulated that such multiphoton ionization of tryptophanyl residues in cellular proteins may contribute to the photodamage observed during imaging of cells and tissues using multiphoton microscopy... 
Active uptake of drugs into photosensitive liposomes and rapid release on UV photolysisR H Bisby
Division of Biological Sciences, School of Environmental and Life Sciences, University of Salford, UK
Photochem Photobiol 72:57-61. 2000..Photoinduced release of pharmacologically active materials from sensitized liposomes might provide a useful adjunct or alternative to conventional photodynamic therapy...- Wavelength-programmed solute release from photosensitive liposomesR H Bisby
Division of Biological Sciences, School of Environmental and Life Sciences, University of Salford, Salford M5 4WT, United Kingdom
Biochem Biophys Res Commun 276:169-73. 2000..It is suggested that the cholesterol-containing liposomes may be potentially useful for drug delivery and for "caging" of reagents... - Structure of the radical from one-electron oxidation of 4-hydroxycinnamateR H Bisby
Division of Biological Sciences, School of Environmental and Life Sciences, University of Salford, Salford, M5 4WT, UK
Free Radic Res 35:85-91. 2001..This contributes to the low reduction potential of the radical and the antioxidant properties of hydroxycinnamates... - Investigation of multiphoton-induced fluorescence from solutions of 5-hydroxytryptophanRoger H Bisby
Biosciences Research Institute, University of Salford, Salford, UK M5 4WT
Photochem Photobiol Sci 2:157-62. 2003..The results indicate that the fluorescence does not originate from the 5-indoxyl radical as previously suggested but from one or more other transient products which require further characterisation... - Single- and multi-photon excited fluorescence from serotonin complexed with beta-cyclodextrinRoger H Bisby
Biosciences Research Institute, University of Salford, Salford, UK
Photochem Photobiol Sci 5:122-5. 2006..The results also suggest that hyperluminescence occurs from multiphoton excitation of a single isolated serotonin molecule... - Quenching of reactive oxidative species by probucol and comparison with other antioxidantsR H Bisby
Department of Biological Sciences, University of Salford, UK
Free Radic Biol Med 20:411-20. 1996..0 x 10(8) M-1 s-1) by more than two orders of magnitude. This difference in reactivity may allow the contribution of singlet oxygen towards oxidative stress to be quantified separately... - Fast laser-induced solute release from liposomes sensitized with photochromic lipid: effects of temperature, lipid host, and sensitizer concentrationR H Bisby
Science Research Institute, University of Salford, Salford, M5 4WT, United Kingdom
Biochem Biophys Res Commun 262:406-10. 1999..The results presented are relevant to the design of photostimulated drug delivery systems and to potential applications of photosensitive liposomes as caging agents for biological effectors... - One-electron oxidation of "photo-Fenton" reagents and inhibition of lipid peroxidationDarren Tobin
Biosciences Research Institute, Peel Building, University of Salford, The Crescent, M5 4WT, Salford, UK
Biochem Biophys Res Commun 299:155-9. 2002..The more reducing properties of MPO result in its activity as an antioxidant and make it less suitable than HPO as a source of hydroxyl radicals for investigation of oxidative stress in biological systems... - Generation of superoxide and singlet oxygen from alpha-tocopherolquinone and analoguesAna G Crisostomo
Biomedical Sciences Research Institute, University of Salford, Salford, UK
Free Radic Res 41:730-7. 2007..8. Such potentially damaging reactions of alpha-TQ may in part account for the recent findings that high levels of dietary vitamin E supplementation lack any beneficial effect and may lead to slightly enhanced levels of overall mortality... - Identification and reactivity of the triplet excited state of 5-hydroxytryptophanS Dad
Biosciences Research Institute, School of Environmental and Life Sciences, University of Salford, Peel Building, The Crescent, Salford, Great Manchester M5 4WT, UK
J Photochem Photobiol B 78:245-51. 2005..3 x 10(8) dm3 mol(-1) s(-1). The results are discussed in the light of recent observations on the multiphoton-excited photochemistry of serotonin... - Formation of singlet oxygen from solutions of vitamin EShakeela Dad
Biosciences Research Institute, University of Salford, Salford M5 4WT, UK
Free Radic Res 40:333-8. 2006..The results are discussed in relation to recent reports on the deleterious effects of vitamin E dietary supplementation and pro-oxidant effects of vitamin E...